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  1. 1421

    The Effective Compound Combination of Bufei Yishen Formula III Improves the Mitochondrial Dysfunction via Inhibiting JNK/Sab Pathway in COPD Mice by Song M, Han M, Zhang H, Yang Y, Tian Y, Li J, Zhao J

    Published 2025-01-01
    “…Mengwei Song,1,2,* Mi Han,1,2,* Haoyu Zhang,1 Yifan Yang,1,2 Yange Tian,1,2 Jiansheng Li,2,3 Jie Zhao1,2 1Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, People’s Republic of China; 2Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Constructed by Henan Province and Education Ministry of P.R. …”
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  2. 1422

    Association Between Weight-Adjusted Waist Index and Cognitive Function in Older Adults Without Diabetes: A Cross-Sectional Study by Wang Q, Yin Y, Liu W, Li L, Wang Z, Tian Y, Fan J

    Published 2025-01-01
    “…Qing Wang,1,* Yishan Yin,2,* Wei Liu,3,* Lingyu Li,1 Zhen Wang,1 Yue Tian,1 Jing Fan1 1Department of Laboratory Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China; 2Department of Orthopedics, The Armed Police Forces Hospital of Shandong, Jinan, Shandong, 250000, People’s Republic of China; 3Department of Emergency Critical Care Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Fan, Department of Laboratory Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China, Email sddzfanjing@163.comBackground: This study investigates the correlation between the weight-adjusted waist index (WWI) and cognitive performance in the senior American population, focusing on those without diabetes from 2011 to 2014.Methods: We analyzed data from the 2011– 2012 and 2013– 2014 National Health and Nutrition Examination Surveys (NHANES), focusing on non-diabetic participants aged 60 and older who completed cognitive tests: Establish a Registry for Alzheimer’s disease (CERAD), the Animal Fluency test (AFT), and Digit Symbol Substitution test (DSST). …”
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  8. 1428

    Characterization of Pancreatic Infections in Patients with Severe Acute Pancreatitis: A Retrospective Study from 2019 to 2023 by Chen Y, Cui Q, Cao J, Wu Q, Lu P, Li G, Sun N

    Published 2025-01-01
    “…Yong Chen,1,* Qichao Cui,2,* Jin Cao,1 Qiuyue Wu,1 Peixuan Lu,1 Gang Li,3 Ning Sun1 1Department of Clinical Laboratory Science, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 2Department of Ultrasound Diagnosis, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 3Department of Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gang Li; Ning Sun, Email nju8icu@126.com; steamsn@163.comObjective: This study investigated the distribution and changes in pancreatic infections among patients with acute pancreatitis (AP) from 2019 to 2023, while exploring the impact of multidrug-resistant bacterial infections on the prognosis of patients with poor outcomes.Methods: This study included patients diagnosed with SAP between 2019 and 2023 and collected the demographic and clinical characteristics of all participants. …”
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  9. 1429
  10. 1430

    Application of Short Peptide Enteral Nutrition in Mechanically Ventilated Critically Ill Children with Severe Pneumonia and Its Impact on Patient Recovery by Xu Z, Ding Y, Deng XM, Mao XX, Xia PF, Li DR, Lu YP

    Published 2025-01-01
    “…Zhe Xu,1 Yi Ding,1 Xue-Mei Deng,1 Xiu-Xiu Mao,1 Ping-Fan Xia,1 Deng-Ran Li,1 Yong-Ping Lu2 1Department of Pediatrics, Guangyuan Central Hospital, Guangyuan, People’s Republic of China; 2Science & Technology Innovation Center, Guangyuan Central Hospital, Guangyuan, People’s Republic of ChinaCorrespondence: Yong-Ping Lu, Science & Technology Innovation Center, Guangyuan Central Hospital, Guangyuan, People’s Republic of China, Email luyongping_lyp@163.comObjective: To explore the application of short-peptide enteral nutrition formulation in mechanically ventilated pediatric patients with severe pneumonia and its impact on rehabilitation outcomes, providing practical clinical evidence for the nutritional support strategy in critically ill pneumonia children.Methods: This study retrospectively analyzed the clinical data of 90 neonatal pneumonia patients undergoing mechanical ventilation from May 2022 to December 2023. …”
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  11. 1431

    Effects of Food on the Pharmacokinetics and Safety of HA121-28 Tablet, a Novel Multi-Targeting Tyrosine Kinase Inhibitor, in Healthy Chinese Subjects: A Phase I Clinical Trial by Liu Y, Li X, Zhang M, Men Y, Wang Y, Zhu X, Zheng L

    Published 2025-01-01
    “…Yixian Liu,1,2,* Xiaoyu Li,1,2,* Mengyu Zhang,1,2 Yuchun Men,1,2 Ying Wang,1,2 Xiaohong Zhu,1,2 Li Zheng1,2 1Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China; 2Clinical Trial Center, NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China*These authors contributed equally to this workCorrespondence: Li Zheng, Cancer Center, West China Hospital, Sichuan University, No. 5 Telecom Road, Wuhou District, Chengdu, 610041, People’s Republic of China, Email zhengli@wchscu.cnPurpose: HA121-28, a novel multi-targeting tyrosine kinase inhibitor, has dual efficacy against tumor growth and neovascularization. …”
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    A Novel COL7A1 Mutation in a Patient With Dystrophic Epidermolysis Bullosa. Successful Treatment With Upadacitinib by Lai S, Lin C, Guo Z, Lai Y, Xie L, Wan C, Yang T, Li L

    Published 2025-01-01
    “…Shuqin Lai,* Chunli Lin,* Zimeng Guo, Yun Lai, Ling Xie, Chunlei Wan, Tao Yang, Longnian Li Department of Dermatology, Candidate Branch of National Clinical Research Centre for Skin and Immune Diseases, First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Tao Yang; Longnian Li, Department of Dermatology, Candidate Branch of National Clinical Research Centre for Skin and Immune Diseases, First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, People’s Republic of China, Email danny20021068@126.com; li_longnian@foxmail.comAbstract: Dystrophic epidermolysis bullosa (DEB) is a heterogeneous and rare genetic skin disease caused by mutations in the COL7A1 gene, which encodes Type VII collagen. …”
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  20. 1440

    Novel Clinical Insights into the Pathogenesis of Posttraumatic Elbow Stiffness: An Expression Profile Analysis of Contracted Joint Capsule in Human by Liu N, Dong J, Li L, Xu J, Yang C, Yu Z, Liu F

    Published 2025-01-01
    “…Nan Liu,1 Jinlei Dong,1 Lianxin Li,1 Jiajun Xu,1 Changhao Yang,1 Zhanchuan Yu,2 Fanxiao Liu1 1Department of Shandong Trauma Center, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jinan, Shandong, 250014, People’s Republic of China; 2Department of Shandong Trauma Center, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250014, People’s Republic of ChinaCorrespondence: Fanxiao Liu, Department of Shandong Trauma Center, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jingshi str. 9677, Jinan, Shandong, 250014, People’s Republic of China, Tel/Fax +86-0531-68773195, Email woshi631@126.com; liufanxiao@sdfmu.edu.cnBackground: Posttraumatic elbow stiffness is a complex complication with two characteristics of capsular contracture and heterotopic ossification. …”
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