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Solid Self-Microemulsifying Drug Delivery System for Improved Oral Bioavailability of Relugolix: Preparation and Evaluation
Published 2025-01-01“…Zi-Lin Li,1,* Guo-Xing Deng,1,* Chuan-Zhou Fang,1,* Yue-Qi Zhao,1 Jing Yuan,2 Liang Chen,3 Hai-Jun Zhong,1 Feng Guo1 1School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China; 2College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang, 471000, People’s Republic of China; 3Jiangxi Prozin Pharmaceutical Co., LTD, Jian, 343100, People’s Republic of China*These authors contributed equally to this workCorrespondence: Feng Guo; Hai-JunZhong, School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China, Tel +86 0791 86361839, Email fengguo@ncu.edu.cn; zhonghj@ncu.edu.cnPurpose: To improve the oral absorption of relugolix (RLGL), which has low oral bioavailability due to its low solubility and being a substrate of P-glycoprotein (P-gp). …”
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Lactate Ameliorates Kainic Acid-Induced Neuroinflammation and Cognitive Impairment via the Chemokine Signaling Pathway in Mice
Published 2025-01-01“…Xiaoqi Chu,1,2,* Yusong Ge,3,* Chao Geng,1,2 Peipei Cao,1,2 Penghu Wei,2 Bin Fu,2 Zihao Deng,4 Yuhao Li,5,6 Guoguang Zhao2,7 1Optometry Institute, School of Medicine Nankai University, Tianjin, People’s Republic of China; 2Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing Municipal Geriatric Medical Research Center, Beijing, People’s Republic of China; 3Department of Neurology, The Second Hospital of Dalian Medical University, Dalian, People’s Republic of China; 4Cancer Center, Capital Medical University, Beijing, People’s Republic of China; 5Central Laboratory, Xuanwu Hospital Capital Medical University, Beijing Municipal Geriatric Medical Research Center, Beijing, People’s Republic of China; 6Department of Pathology, School of Medicine Nankai University, Tianjin, People’s Republic of China; 7National Medical Center for Neurological Diseases, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guoguang Zhao, Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing Municipal Geriatric Medical Research Center, Beijing, People’s Republic of China, Email ggzhao@vip.sina.com Yuhao Li, Central Laboratory, Xuanwu Hospital Capital Medical University, Beijing Municipal Geriatric Medical Research Center, Beijing, People’s Republic of China, Email liyuhao@xwhosp.orgPurpose: Lactate, previously considered a metabolic waste product, has been shown to have neuroprotective potential. …”
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Association of C-Reactive Protein with Short-Term Outcomes in Spontaneous Intracerebral Hemorrhage Patients with or without Infection: From a Large-Scale Nationwide Longitudinal Re...
Published 2025-01-01“…Yang Du,1,2 Lijun Liu,1,2 Kaijiang Kang,1,2 Yijun Lin,1,2 Hongqiu Gu,1,2 Liheng Bian,1,2 Zixiao Li,1,2 Xingquan Zhao1– 4 1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, People’s Republic of China; 3Research Unit of Artificial Intelligence in Cerebrovascular Disease, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 4Center of Stroke, Beijing Institute for Brain Disorders, Beijing, People’s Republic of ChinaCorrespondence: Xingquan Zhao; Zixiao Li, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, 119 West Road, South 4th Ring, Fengtai District, Beijing, People’s Republic of China, 100070, Tel +86-10-59975835, Email lizixiao2008@hotmail.com; zxq@vip.163.comAim: To study the relationship between elevated C-reactive protein (CRP) levels, infection, and spontaneous intracerebral hemorrhage (ICH) outcomes.Methods: Patients were classified into four groups (Q1–Q4). …”
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Investigating the Use of Generative Adversarial Networks-Based Deep Learning for Reducing Motion Artifacts in Cardiac Magnetic Resonance
Published 2025-02-01“…Ze-Peng Ma,1,2,* Yue-Ming Zhu,3,* Xiao-Dan Zhang,4 Yong-Xia Zhao,1 Wei Zheng,3 Shuang-Rui Yuan,1 Gao-Yang Li,1 Tian-Le Zhang1 1Department of Radiology, Affiliated Hospital of Hebei University/ Clinical Medical College, Hebei University, Baoding, 071000, People’s Republic of China; 2Hebei Key Laboratory of Precise Imaging of inflammation Tumors, Baoding, Hebei Province, 071000, People’s Republic of China; 3College of Electronic and Information Engineering, Hebei University, Baoding, Hebei Province, 071002, People’s Republic of China; 4Department of Ultrasound, Affiliated Hospital of Hebei University, Baoding, Hebei Province, 071000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiao-Dan Zhang, Department of Ultrasound, Affiliated Hospital of Hebei University, No. 212 of Yuhua East Road, Lianchi District, Baoding, 071000, People’s Republic of China, Tel +86 17325535302, Email xiaodanzhangzxd@126.comObjective: To evaluate the effectiveness of deep learning technology based on generative adversarial networks (GANs) in reducing motion artifacts in cardiac magnetic resonance (CMR) cine sequences.Methods: The training and testing datasets consisted of 2000 and 200 pairs of clear and blurry images, respectively, acquired through simulated motion artifacts in CMR cine sequences. …”
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Lesion Location and Possible Etiology of Acute Unilateral Vestibulopathy
Published 2025-01-01“…Menglu Zhang,1,2,* Jianrong Wang,1,2,* Siru Xue,1 Shui Liu,3 Kangzhi Li,4 Tongtong Zhao,1,2 Yufei Feng,1,2 Rubo Sui,2 Bentao Yang,5 Xu Yang1 1Department of Neurology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, 100049, People’s Republic of China; 2Department of Neurology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, 121001, People’s Republic of China; 3Department of Radiology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, 100049, People’s Republic of China; 4Department of Neurology, Peking University Shougang Hospital, Beijing, 100144, People’s Republic of China; 5Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xu Yang, Department of Neurology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, 15 Yuquan Road, Haidian District, Beijing, 100049, People’s Republic of China, Tel +86010-59971978, Email yangxu2011@163.com Bentao Yang, Department of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1, Dongjiaomin Lane, Dongcheng District, Beijing, 100730, People’s Republic of China, Tel +86 13671281401, Email cjr.yangbentao@vip.163.comObjective: Acute unilateral vestibulopathy (AUVP) is quite common in clinical practice, but lesion localization and etiological diagnosis of AUVP remain the current clinical challenges, and have always been the focus for researchers. …”
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Integrated Microbiome and Metabolome Analysis Reveals Correlations Between Gut Microbiota Components and Metabolic Profiles in Mice With Mitoxantrone-Induced Cardiotoxicity
Published 2025-01-01“…Qing Zhang,1 Deshuai Liang,2 Chengfang Zhang,3 Ling Ye,4 Ping Sun,4 Hongli Zhu,4 Yongqin Zhao,4 Yuewen Li,4 Yun Guan,4 Haiguo Zhang4 1College of Clinical Medicine, Jining Medical University, Jining, 272013, People’s Republic of China; 2Department of Pharmacy, Jining NO. 1 People’s Hospital, Jining, 272000, People’s Republic of China; 3Department of Clinical Laboratory, Jining NO. 1 People’s Hospital, Jining, 272000, People’s Republic of China; 4Department of Hematology, Jining NO. 1 People’s Hospital, Jining, 272000, People’s Republic of ChinaCorrespondence: Haiguo Zhang; Yun Guan, Jining NO. 1 People’s Hospital, 6 Jiankang Road, Jining Shandong, 272000, People’s Republic of China, Tel/Fax +86-0537 2257626 ; +86-0537 2087093, Email wfmchero@126.com; gyuanun1989@163.comPurpose: Mitoxantrone (MTX) is largely restricted in clinical usage due to its significant cardiotoxicity. …”
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Prospective Single-Arm Study of Remifentanil-Propofol Anesthesia with Manual Right Hypochondrial Compression for Painless Gastroscopy in Obese Patients
Published 2025-02-01“…Mengxia Wang,1,* Jieke Tang,1,* Zhaojie Pan,2 Hongxue Jiang,1 Donghua Hu,1 Beibei Zhu,2 Zhaojia Liang,1 Xiangfeng Zhao,1 Yalan Li1 1Department of Anesthesiology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People’s Republic of China; 2Department of Digestive Endoscopy Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yalan Li, Department of Anesthesiology, The First Affiliated Hospital of Jinan University, No. 613, Huangpu West Avenue, Tianhe District, Guangzhou, Guangdong Province, 510630, People’s Republic of China, Email tyalan@jnu.edu.cnPurpose: The provision of comfortable and safe environment for painless gastroscopy in obese patients is an urgent clinical problem. …”
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Auricular Acupuncture for Perioperative Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Published 2025-01-01“…Yan Zhou,1,* Qiongnan Bao,1,* Chen Yang,1,* Shuhao Li,1,* Zihan Yin,1 Jian Xiong,1 Mingsheng Sun,1 Jiao Yang,2 Fang Liu,3 Fanrong Liang1 1Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 3Department of Integrated Chinese and Western Medicine, Sichuan Cancer Hospital, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fanrong Liang, Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610075, People’s Republic of China, Email acuresearch@126.com Fang Liu, Department of Integrated Chinese and Western Medicine, Sichuan Cancer Hospital, Chengdu, Sichuan, 610041, People’s Republic of China, Email liufang@scszlyy.org.cnPurpose: We conducted a more comprehensive systematic review and meta-analysis to evaluate the effectiveness of auricular acupuncture (AA) in perioperative pain management.Methods: Randomized controlled trials (RCTs) findings were retrieved from the Embase, Cochrane Central Register of Controlled Trials, PubMed, Web of Science, Chinese Biomedical Literature Database, Wanfang, VIP, and China National Knowledge Infrastructure databases from their inception to March 2024 using the search terms “pain”, “auriculotherapy”, and “randomized controlled trial”. …”
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Study on the Mechanism of Black Phosphorus Nanosheets Loading Sr2+ Used in Photothermal Antibacterial Treatment
Published 2025-01-01“…Gaoqiang Ma,1,* Binyang Li,1,* Jiayong Diao,1 Yongzhi Zhang,1 Bing Zhang,1 Dongni Wu,1 Houda Gui,1 Junhao Zhong,1 Hongguang Zhu,2 Dongjiao Zhang1 1Department of Implantology, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, People’s Republic of China; 2Department of Stomatology, Weifang People’s Hospital, Weifang, 261000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dongjiao Zhang; Hongguang Zhu, Email djzhang1109@sdu.edu.cn; zhuhongguang9025@126.comPurpose: Bacterial infections seriously affect the health of patients and their incidence is very high. …”
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91
A Novel Pathogenic Splicing Mutation of OFD1 is Responsible for a Boy with Joubert Syndrome Exhibiting Orofaciodigital Spectrum Anomalies, Polydactyly and Retinitis Pigmentosa
Published 2025-02-01“…Liang Chen,1,* Mei-Fang Zhao,2,* Hui-Wen Deng,1 Min Liao,1 Liang-Liang Fan,2 Qi-Bao Zhong,3 Jun Wang,1 Ke Li,1 Zheng-Hui Wu,4,* Jian-Yin Yin1 1Department of Anesthesiology, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410008, People’s Republic of China; 2Department of Cell Biology, School of Life Sciences, Central South University, Changsha, 410013, People’s Republic of China; 3Department of Facial Features, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410008, People’s Republic of China; 4Department of Child Rehabilitation, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410008, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian-Yin Yin, Department of Anesthesiology, Hunan Provincial Maternal and Child Health Care Hospital. …”
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Impact of Hyperglycemia on Tear Film and Meibomian Gland Dysfunction: A Cross-Sectional Study
Published 2025-02-01“…Fanhua Meng,1,* Yuan Zhou,2,* Tong Bao,1,* Yunlei Pang,1 Qinglei Shao,1 Lifeng Wang,1 Jing Zhao,1 Wenchao Li,1 Haiyan Xu,1 Yajun Yang,1,2 Bozhou Zhang1,2 1Department of Retinal, Chifeng Chaoju Eye Hospital, Chifeng, People’s Republic of China; 2Department of Ocular Surface, Baotou Chaoju Eye Hospital, Baotou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yajun Yang; Bozhou Zhang, Department of ocular surface, Baotou Chaoju Eye Hospital, Baotou, Inner Mongolia Autonomous Region, 014060, People’s Republic of China, Email yangyajun@chaojueye.com; zhangbozhou@chaojueye.comPurpose: Elevated blood glucose levels may disrupt tear film and meibomian gland function, contributing to dry eye disease (DED) and meibomian gland dysfunction (MGD). …”
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Molecular and Transmission Characteristics of Mycobacterium Tuberculosis Strains Among College Students in Beijing, China
Published 2025-01-01“…Xiaolong Cao,1,2,* Xinyue Li,1,3,* Zexuan Song,4 Ping He,5 Ruiqing Zhang,1,3 Chong Teng,6 Qian Sun,2 Xue Wang,2 Bing Zhao,3 Zhiguo Zhang,7 Yanlin Zhao3 1National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People’s Republic of China; 2Outpatient Department, Beijing Changping Institute for Tuberculosis Prevention and Treatment, Beijing, 102200, People’s Republic of China; 3National Tuberculosis Reference Laboratory, Chinese Center for Disease Control and Prevention, Beijing, 102206, People’s Republic of China; 4Department of Clinical Laboratory, Children’s Hospital, Capital Institute of Pediatrics, Beijing, 100020, People’s Republic of China; 5Center for Infection Biology, School of Medicine, Tsinghua University, Beijing, 100084, People’s Republic of China; 6Tuberculosis Prevention and Control Department, Beijing Dongcheng District Center for Disease Control and Prevention, Beijing, 100050, People’s Republic of China; 7Hospital Management Office, Beijing Changping Mental Health Care Hospital, Beijing, 102202, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiguo Zhang, Beijing Changping Mental Health Care Hospital, Changping District, Beijing, 102202, People’s Republic of China, Email zhgzh8689@126.com Yanlin Zhao, National Tuberculosis Reference Laboratory, Chinese Center for Disease Control and Prevention, Changping District, Beijing, 102206, People’s Republic of China, Email zhaoyl@chinacdc.cnBackground: College students are a crucial link in curbing the epidemic. …”
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94
Predictors and Prognostic Effects of Perioperative Myocardial Injury After Transcatheter Aortic Valve Replacement According to VARC-3 Criteria
Published 2025-02-01“…Xiangming Hu,1,* Zhenyan Zhao,1,* Can Wang,1,* Dejing Feng,1 Yang Chen,2 Guannan Niu,1 Zheng Zhou,1 Hongliang Zhang,1 Zhe Li,1 Yunqing Ye,1 Moyang Wang,1 Yongjian Wu1 1Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; 2Department of Cardiology, Peking University People’s Hospital, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Moyang Wang; Yongjian Wu, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, People’s Republic of China, Email wangmoyang1983@vip.sina.com; fuwaiwyj@163.comPurpose: The impact of periprocedural myocardial injury (PPMI) according to VARC-3 criteria in patients undergoing transcatheter aortic valve replacement (TAVR) remains unclear. …”
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Progress in the Study of Intratumoral Microorganisms in Hepatocellular Carcinoma
Published 2025-01-01“…Yagang Song,1,2 Shuo Tian,1,2 Zhanzhan Li,1,2 Jinxin Miao,1,2 Mingming Wu,1,2 Tingli Xu,1,2 Xiangxiang Wu,1,2 Jingyi Qiao,1,2 Xialei Zhang,1,3 Hui Zhao,1,2 Le Kang,1,3 Lihua Cao,1,2 Pingsheng Zhu,4 Mingsan Miao1 1Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China; 2Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China; 3School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China; 4College of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of ChinaCorrespondence: Mingsan Miao, Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China, Tel/Fax +86-371-65962546, Email miaomingsan@163.comAbstract: The intratumoral microbiota, an integral part of liver tumors, has garnered significant attention from researchers due to its role in tumor development regulation and impact on cancer treatment. …”
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Association Between Diurnal Temperature Range and Risk of Cardiomyopathy-Induced Hospitalisation in Henan, China: A Time-Series Study
Published 2025-01-01“…Zhaolin Zhang,1,* Yongbin Wang,2,* Yifeng Zhou,1 Jiachao Pei,1 Guoan Zhao,1,3 Pingshuan Dong,4 Kan Yang,5 Hui Liu,6 Na Xie,7 Xuefang Li,3 Xiayan Zang,3 Fei Lin,1,3 Zhigang Chen1 1Department of Cardiology,The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, People’s Republic of China; 2Department of Epidemiology and Health Statistics, Xinxiang Medical University, Xinxiang, 453003, People’s Republic of China; 3Henan Engineering Technology Research Center of Environmental Meteorological Medicine, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, People’s Republic of China; 4Department of Cardiology,The First Affiliated Hospital of Henan University of Science and Technology, Luoyan, 471000, People’s Republic of China; 5Department of Cardiology,Nanyang Central Hospital, Nanyang, 473005, People’s Republic of China; 6Department of Cardiology,Anyang District Hospital, Anyang, 455000, People’s Republic of China; 7Department of Cardiology,The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, 453003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fei Lin; Zhigang Chen, Department of Cardiology,The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui, Henan, People’s Republic of China, Tel +86 18567557937, Email 1fy2000129@xxmu.edu.cn; 1fy2015157@xxmu.edu.cnPurpose: The effect of the diurnal temperature range (DTR) on human health in diverse geographic areas and the potential confounding factors are not fully understood. …”
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TRACE Model: Predicting Treatment Response to Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma
Published 2025-01-01“…Weilang Wang,1,* Qi Zhang,2,* Ying Cui,1,* Shuhang Zhang,1 Binrong Li,1 Tianyi Xia,1 Yang Song,3 Shuwei Zhou,1 Feng Ye,4 Wenbo Xiao,5 Kun Cao,6 Yuan Chi,7 Jinrong Qu,8 Guofeng Zhou,9,10 Zhao Chen,11 Teng Zhang,12 Xunjun Chen,13 Shenghong Ju,1 Yuan-Cheng Wang1 1Department of Radiology, Zhongda Hospital, Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology, School of Medicine, Southeast University, Nanjing, 210009, People’s Republic of China; 2Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, People’s Republic of China; 3MR Scientific Marketing, Siemens Healthineers Ltd, Shanghai, People’s Republic of China; 4Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; 5Department of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 6Department of Radiology, Peking University Cancer Hospital and Institute, Beijing, People’s Republic of China; 7Department of Radiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China; 8Department of Radiology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, Henan, People’s Republic of China; 9Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China; 10Shanghai Institute of Medical Imaging, Shanghai, People’s Republic of China; 11Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China; 12Institute for Artificial Intelligence in Medicine, School of Artificial Intelligence, Nanjing University of Information Science and Technology, Nanjing, People’s Republic of China; 13Department of Radiology, The People’s Hospital of Xuyi County, Huaian, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuan-Cheng Wang, Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology, Department of Radiology, Zhongda Hospital, School of Medicine, Southeast University, 87 Ding Jia Qiao Road, Nanjing, Jiangsu, 210009, People’s Republic of China, Tel +086 25 83272121, Fax +086 25 83311083, Email yuancheng_wang@seu.edu.cnPurpose: To develop and validate a predictive model for predicting six-month outcome by integrating pretreatment MRI features and one-month treatment response after TACE.Methods: A total of 108 patients with 160 hCCs from a single-arm, multicenter clinical trial (NCT03113955) were analyzed and served as the training cohort. …”
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Intralesional Spesolimab: A Novel and Effective Approach for Palmoplantar Pustulosis Treatment – A Case Report
Published 2025-01-01“…Si-Ning Wang,* Yi-Zhou Lu,* Yujuan Zhao, Wei Cao, Rui-Li Zhang Department of Dermatology, The Second Affiliated Hospital Nanjing Medical University, Nanjing Medical University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Rui-Li Zhang, Department of Dermatology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, 210003, People’s Republic of China, Email rellyzhang@njmu.edu.cnAbstract: Palmoplantar pustulosis (PPP) is a chronic condition characterized by the presence of sterile pustules on the palms and soles of the feet. …”
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Cucurbitacin IIa Alleviates Colitis via Promoting the Release of Host-Derived Extracellular Vesicles Encapsulating microRNA-30b-5p
Published 2025-01-01“…Yinyin Zhao,1 Binyuan Jiang,2 Shengnan Zuo3 1Ningbo Institute of Innovation for Combined Medicine and Engineering (NIIME), The Affiliated LiHuiLi Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Medical Research Center of the Affiliated Changsha Central Hospital of Hengyang Medical School, University of South China, Changsha, People’s Republic of China; 3Clinical Laboratory Department, Hunan Guangxiu Hospital, Changsha, People’s Republic of ChinaCorrespondence: Binyuan Jiang; Shengnan Zuo, Email 2018050871@usc.edu.cn; shengnanzuo123@sina.comPurpose: Cucurbitacins have demonstrated anti-inflammatory effects and show promise for inflammatory bowel diseases. …”
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Special issue: Proceedings of the 15th ISIC - The Information Behaviour Conference, Aalborg, Denmark, August 26-29, 2024
Published 2024-06-01“…Preliminary findings from a cross-sectional study of online medical consultation Siqi Luo, Hongyi Qin, Hanlin Li, Cui Huang Mapping the road ahead: understanding social factors that shape vehicle residents’ information grounds Kaitlin E. …”
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