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A Bidirectional Mendelian Randomization Study Investigating the Causal Relationship Between Ankylosing Spondylitis and Chronic Obstructive Pulmonary Disease
Published 2025-02-01“…Di Pan,1,2 Xiaoling Dai,3 Pan Li,4 Luan Xue1 1Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3Shanghai Putuo Traditional Chinese Medicine Hospital, Shanghai, People’s Republic of China; 4Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of ChinaCorrespondence: Luan Xue; Xiaoling Dai, Email 610725556@qq.com; 553137182@qq.comBackground: Previous studies have found an association between ankylosing spondylitis (AS) and chronic obstructive pulmonary disease (COPD); however, no research has investigated this relationship using Mendelian randomization (MR).Methods: This study employed a bidirectional two-sample MR approach to assess the causal connection between AS and COPD. …”
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