Scent of COVID-19: Whole-Genome Sequencing Analysis Reveals the Role of <i>ACE2</i>, <i>IFI44</i>, and <i>NDUFAF4</i> in Long-Lasting Olfactory Dysfunction by Beatrice Spedicati, Alessandro Pecori, Maria Pina Concas, Aurora Santin, Romina Ruberto, Giuseppe Giovanni Nardone, Andrea D’Alessandro, Giancarlo Tirelli, Paolo Boscolo-Rizzo, Giorgia Girotto

“…COVID-19-related persistent olfactory dysfunction (OD) presents remarkable interindividual differences, and little is known about the host genetic factors that are involved in its etiopathogenesis. …”
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Advances of wearable silicone rubber-based triboelectric nanogenerators: from manufacturing to application by Dianlong Shen, Taili Du, Fangyang Dong, Hu Cai, Aziz Noor, Xiannan Du, Yongjiu Zou, Chengkuo Lee, Minyi Xu

“…Wearable bioelectronic devices are rapidly evolving towards miniaturization and multifunctionality, with remarkable features such as flexibility and comfort. …”
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Small-scale land use effects on plant communities in Mediterranean urban ecosystems by Vincenzo Baldi, Alessandro Bellino, Daniela Baldantoni

“…Overall, results indicate a remarkable heterogeneity of plant communities, even at scales in the order of few meters, with land use and margin effect differentially affecting their structural and functional biodiversity. …”
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Comparison of chicoric acid, and its metabolites caffeic acid and caftaric acid: In vitro protection of biological macromolecules and inflammatory responses in BV2 microglial cells by Qian Liu, Fan Liu, Liling Zhang, Yajie Niu, Zhigang Liu, Xuebo Liu

“…Moreover, CA, CTA and CFA all exerted remarkable inhibition capacities on linoleic acid and soybean lecithin liposomes peroxidation in a dose-dependent manner, and restrained the oxidation of herring sperm DNA, as well as the breakage of pBR322 plasmid DNA. …”
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A Novel Secretory Vesicle from Deer Antlerogenic Mesenchymal Stem Cell-Conditioned Media (DaMSC-CM) Promotes Tissue Regeneration by Minkoo Seo, Jin-Chul Kim, Hyung-Ki Kim, Eun wook Choi, Suyeong Jeong, Ki Chang Nam, Mihue Jang

“…In addition, DaMSC-CM had regenerative potential in damaged skin tissue through induction of skin regeneration-related genes. Remarkably, we identified round vesicles derived from DaMSC-CM, with an average diameter of ~120 nm that were associated with hair follicle formation, suggesting that secretory vesicles may act as paracrine mediators for modulation of local cellular responses. …”
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PD-L1 Expression and CD8+ T Cell Infiltration Predict a Favorable Prognosis in Advanced Gastric Cancer by Yangyang Wang, Chunchao Zhu, Wei Song, Jun Li, Gang Zhao, Hui Cao

“…Programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors have exhibited remarkable activity in clinical trials and were approved by the FDA for clinical therapy in several types of tumors. …”
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Digital twin-centered hybrid data-driven multi-stage deep learning framework for enhanced nuclear reactor power prediction by James Daniell, Kazuma Kobayashi, Ayodeji Alajo, Syed Bahauddin Alam

“…By leveraging a combination of feed-forward neural networks with both classification and regression stages, and training on a unique dataset that integrates real-world measurements of reactor power and controls state from the Missouri University of Science and Technology Reactor (MSTR) with noise-enhanced simulated data, our approach achieves remarkable accuracy (96% classification, 2.3% MAPE). …”
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Associations between neutrophil percentage to albumin ratio and rheumatoid arthritis versus osteoarthritis: a comprehensive analysis utilizing the NHANES database by Wenquan Ding, Rui La, Shenghao Wang, Zhiyuan He, Dinghua Jiang, Zhigang Zhang, Hao Ni, Wu Xu, Lixin Huang, Qian Wu, Qian Wu

“…This association was remarkably consistent across subgroups by age, sex, body mass index (BMI), alcohol consumption, hypertension, diabetes, and smoking status. …”
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The first cases of collagenous sprue successfully treated with thioguanine by Chris J J Mulder, Gerd Bouma, Tom van Gils, Tine van de Donk, Foke van Delft, E Andra Neefjes-Borst

“…All patients improved remarkably. Normalisation of the thickened basement membrane was found in 2 patients and complete histological improvement including full recovery of villi was found in 1 patient. …”
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Therapeutic Effect of Zataria Multiflora Essential Oil on Burn Wound Infected by Pseudomonas aeruginosa by Maryam Zare, Elahe Sattarinezhad, Ali Karimi Akhormeh, Maryam Motevasel, Marzieh Ashrafmansouri, Maral Mokhtari, Omid Koohi Hosseinabadi, Aida Iraji, Azar Purkhosrow

“…The results showed that on the 7th day, while a significant healing of the wounds was observed in the ZMEO group, the other groups did not show remarkable wound healing (P<0.05). Therefore, ZMEO showed an accelerating effect on the healing process of burn wounds and could be considered for further evaluations in order to develop new medications for the treatment of burn wounds infected with P. aeruginosa.…”
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Enhancing sulfide stress cracking resistance of a Cu-bearing high strength low alloyed steel through decreasing austenitizing temperature by Tianyi Zeng, Qingzhan Zhang, Shuzhang Zhang, Yong Zhou, Yinghui Zhao, Xianbo Shi, Wei Yan

“…Moreover, although dislocations remarkably decreased the effective hydrogen diffusion coefficient (D0), these trapped hydrogen atoms could readily detrap, increasing the apparent hydrogen solubility (Capp). …”
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Winter tick sharing between ungulates in the Greater Yellowstone Ecosystem and implications for apparent competition by Troy Koser, Alynn Martin, Alyson Courtemanch, Laura Thompson, Benjamin Wise, Gary Fralick, Sarah Dewey, Amy Girard, Brandon Scurlock, Jared Rogerson, Kennan Oyen, Paul Cross

“…We found that winter tick infestation loads did not vary remarkably between both host species and winter ticks sourced from elk and moose produced similar numbers of larvae which activated within 5 days of each other. …”
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Photoirradiation Caused Controllable Wettability Switching of Sputtered Highly Aligned c-Axis-Oriented Zinc Oxide Columnar Films by P. W. Chi, C. W. Su, B. H. Jhuo, D. H. Wei

“…After exposing to photoirradiation under ultraviolet (UV) environment, all the ZnO samples showed remarkable transition from hydrophobic to superhydrophilic surfaces and could return to their original hydrophobicity after being placed in the dark. …”
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Effects of IQW and IRW on Inflammation and Gut Microbiota in ETEC-Induced Diarrhea by Naiyuan Liu, Lingsi Zhou, Jun Fang, Hongmei Jiang, Gang Liu

“…The active triple peptides, lle-Gln-Trp (IQW) and lle-Arg-Trp (IRW), cause remarkable changes to gut microbiota. The effects of the triple peptides IQW and IRW in gut-damage treatment were explored in this study via an enterotoxigenic Escherichia coli- (ETEC-) induced mouse model. …”
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Deletion of the waaf gene affects O antigen synthesis and pathogenicity in Vibrio parahaemolyticus from shellfish by Feng Zhao, Guoying Ding, Qilong Wang, Huihui Du, Guosheng Xiao, Deqing Zhou

“…Growth curves showed no remarkable differences between the WT and Δwaaf strains. …”
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Regeneration of Tracheal Tissue in Partial Defects Using Porcine Small Intestinal Submucosa by Nelson Bergonse Neto, Lianna Ferrari Jorge, Julio C. Francisco, Bruna Olandoski Erbano, Barbara Evelin Gonçalves Barboza, Larissa Luvison Gomes da Silva, Marcia Olandoski, Katherine Athayde Teixeira de Carvalho, Luiz Felipe Pinho Moreira, Jose Rocha Faria Neto, Eltyeb Abdelwahid, Luiz Cesar Guarita-Souza

“…Although tracheal SIS engraftment could not prevent stenosis in a rabbit model of tracheal injury, it produced some remarkable changes, efficiently facilitating neovascularization, reepithelialization, and neoformation of immature cartilage.…”
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Seasonal Variation in Vitamin D in Association with Age, Inflammatory Cytokines, Anthropometric Parameters, and Lifestyle Factors in Older Adults by Leticia Elizondo-Montemayor, Elena C. Castillo, Carlos Rodríguez-López, José R. Villarreal-Calderón, Merit Gómez-Carmona, Sofia Tenorio-Martínez, Bianca Nieblas, Gerardo García-Rivas

“…Age (>74 years) combined with WC (>88 cm) and BMI (>32.7) showed a high probability (90%) of vitamin D deficiency. Remarkably, an increase in one centimeter in WC decreased 25(OH)D by 0.176 ng/mL, while an increase in one point BMI decreased 25(OH)D by 0.534 ng/mL. …”
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Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Lear... by Zhilu Zou, Yin Chen, Qinqin Shen, Xiaoyan Guo, Yuxuan Zhang, Gang Chen

“…Repeated administration of Yueju following chronic LH remarkably alleviated all of depressive-like symptoms measured, whereas conventional antidepressant fluoxetine only showed a minor improvement. …”
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GEN-27, a Newly Synthetic Isoflavonoid, Inhibits the Proliferation of Colon Cancer Cells in Inflammation Microenvironment by Suppressing NF-κB Pathway by Yajing Wang, Ping Lu, Weifeng Zhang, Qianming Du, Jingjing Tang, Hong Wang, Jinrong Lu, Rong Hu

“…Further mechanistic study revealed that GEN-27 remarkably inhibited the nuclear translocation of NF-κB and phosphorylation of IκB and IKKα/β in both HCT116 and THP-1 cells. …”
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99mTc-labeled benzenesulfonamide derivative-entrapped gold citrate nanoparticles as an auspicious tumour targeting by Adli A. Selim, Tamer M. Sakr, Basma M. Essa, Galal H. Sayed, Kurls E. Anwer

“…Compound 3 (4-((3-cyano-4-(2,4-dichlorophenyl)-6-phenylpyridin-2-yl)amino)-N-(diaminomethylene)benzenesulfonamide) exhibited remarkable anti-cancer activity against MCF-7 cells. …”
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