Spontaneous Recovery of Paraplegia in a Polytrauma Patient following Spinal Cord Ischemia due to Type B Traumatic Aortic Dissection by Pedro Ramos Jurado, Fernando Hernández Aragón, Víctor Aaron Miranda González, Jesús Antonio Loya Silva, Edgar Azael Pérez Gutiérrez, Nadia Karina Portillo Ortiz, Adriana Cristina Quintana Vázquez, Luisa Fernanda Trujillo Venzor, Eduardo Enrique Gámez Aponte, Arturo Aguirre Madrid, Edmundo Berumen Nafarrate

“…In this case study, a 65-year-old male engaged in a car accident is admitted to urgent care with a traumatic aortic dissection diagnosis that included the aortic arch, a segmental exposed fracture of 1/3 distal of the right femur AO 32C3k, and an intertrochanteric fracture AO 31A1.3. …”
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Safety of influenza vaccination during pregnancy: a systematic review by Brian Hutton, David Moher, Danielle B Rice, Claire Butler, Andrea C Tricco, Becky Skidmore, Candyce Hamel, Chantelle Garritty, Paul A Khan, Marco Ghassemi, Charlene Soobiah, Leila Esmaeilisaraji, Dianna M Wolfe, Deshayne Fell, Mona Hersi, Nadera Ahmadzai, Alan Michaud, Angela Sinilaite

“…All evidence was of very low certainty.Conclusions Evidence of very low certainty suggests that seasonal influenza vaccination during pregnancy is not associated with adverse birth outcomes or maternal non-obstetric SAEs. …”
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Water-mediated ion transport in an anion exchange membrane by Zhongyang Wang, Ge Sun, Nicholas H. C. Lewis, Mrinmay Mandal, Abhishek Sharma, Mincheol Kim, Joan M. Montes de Oca, Kai Wang, Aaron Taggart, Alex B. Martinson, Paul A. Kohl, Andrei Tokmakoff, Shrayesh N. Patel, Paul F. Nealey, Juan J. de Pablo

“…It plays a central role in ion transport in electrochemical systems. Gaining a better understanding of molecular transport and conductivity in AEMs has been challenged by the lack of a general methodology capable of capturing and connecting water dynamics, water structure, and ionic transport over time and length scales ranging from those associated with individual bond vibrations and molecular reorientations to those pertaining to macroscopic AEM performance. …”
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Exploring the experiences of healthcare professionals in South Africa and Uganda around communicating with children about life-threatening conditions: a workshop-based qualitative... by Sue Ziebland, Julia Ambler, Julia Downing, Alan Stein, Elizabeth Namukwaya, Elizabeth Nabirye, Louise Walker, Elizabeth Rapa, Jeffrey R Hanna, Louise J Dalton, Teresa Pollard, Stephanie Santos-Paulo, Yasmin Gogay, David Kavuma, Ruth Mary Kemigisha, Juliet Namyeso, Tracey Brand, Beverley G Neethling

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Research progress and perspectives on the application of tyramide signal amplification-based multiplex immunohistochemistry/immunofluorescence: a bibliometrics analysis by Xiaotong Yu, Xiaotong Yu, Chen Huang, Chen Huang, Yan Song, Yan Song, Chun Zhang, Chun Zhang, Debo You, Debo You, XuRan Dong, XuRan Dong, DeFu Wu, DeFu Wu, Alan Keith Meeker, Hao Feng, Yuqing Wang, Yuqing Wang

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Impact of individual, household, and area characteristics on health and social care outcomes for people with multimorbidity: Protocol for a multilevel analysis. by Clare MacRae, Stewart W Mercer, Andrew Lawson, Alan Marshall, Jamie Pearce, Eleojo Abubakar, Chunyu Zheng, Marjan van den Akker, Thomas Williams, Olivia Swann, Louisa Pollock, Anna Rawlings, Rich Fry, Ronan A Lyons, Jane Lyons, Amy Mizen, Chris Dibben, Bruce Guthrie

“…This study protocol presents a plan for the examination of associations between individual, household, and area characteristics with important health and social care outcomes.…”
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Post COVID glaucoma service redesign utilising electronic patient triage and community optometry clinics (Fife, Scotland 2020—2022) by Niharika Nalagatla, Shameela Parveen, Kelvin KW Cheng, Caroline Styles, Andrew Blaikie, Peter Wilson, Bhavani Karri, David J Chinn, Roshini Sanders, Glaucoma Team, Lisa Wong, Alan Ramsay, Steven Halstead, Michelle Boulton, David Cummins, Colin Ferrier, Gavin Galloway, Elizabeth Embrey, Duncan Preston

“…Conclusion Glaucoma patients in Scotland can be appropriately triaged to glaucoma accredited community optometry clinics. …”
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The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques. by Alexander M Cole, Dorothy L Patton, Lisa C Rohan, Amy L Cole, Yvonne Cosgrove-Sweeney, Nicole A Rogers, Deena Ratner, Alexandra B Sassi, Carol Lackman-Smith, Patrick Tarwater, Bharat Ramratnam, Piotr Ruchala, Robert I Lehrer, Alan J Waring, Phalguni Gupta

“…<h4>Background</h4>RC-101 is a congener of the antiretroviral peptide retrocyclin, which we and others have reported is active against clinical HIV-1 isolates from all major clades, does not hemagglutinate, and is non-toxic and non-inflammatory in cervicovaginal cell culture. …”
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Building a Community-Centered Clinical Research Center in an Underserved New York City Neighborhood to Enhance Access to Research, Equity, and Quality of Care by Amin Yakubov, James Holahan, Aaron Lord, Melanie Jay, Rachel Gross, Celia Engelson, Zariya Alvarez, Miguel Rodriguez, Leomaris Caba Caceres, Michael Reyes, Emily Drum, Xiaoting Xing, Rosario Medina, Shilpa Londhe, Brita Roy, Imad Alsayed, Gabrielle Gold-von Simson, Miriam A. Bredella

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Intranigral Administration of β-Sitosterol-β-D-Glucoside Elicits Neurotoxic A1 Astrocyte Reactivity and Chronic Neuroinflammation in the Rat Substantia Nigra by Claudia Luna-Herrera, Irma A. Martínez-Dávila, Luis O. Soto-Rojas, Yazmin M. Flores-Martinez, Manuel A. Fernandez-Parrilla, Jose Ayala-Davila, Bertha A. León-Chavez, Guadalupe Soto-Rodriguez, Victor M. Blanco-Alvarez, Francisco E. Lopez-Salas, Maria E. Gutierrez-Castillo, Bismark Gatica-Garcia, America Padilla-Viveros, Cecilia Bañuelos, David Reyes-Corona, Armando J. Espadas-Alvarez, Linda Garcés-Ramírez, Oriana Hidalgo-Alegria, Fidel De La Cruz-lópez, Daniel Martinez-Fong

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Meeting Report on “The International Congress on Autoimmune Pre-disease (2024)” by Justus Ohmes, Afsaneh Mehrpouyan, Julia Wimmer-Groß, Abdul Razzaque Ahmed, Kyle T. Amber, Swayanka Biswas, Angela Christiano, Shirin Emtenani, Stephanie Goletz, Jennifer Elisabeth Hundt, Laura Kirchhoff, Khalaf Kridin, Julie Lasselin, Matthias Laudes, Wing Yu Lee, Ralf J. Ludwig, Sripriya Murthy, Sadegh Mousavi, Tamas Nemeth, Mareike Neumann, Isa Popken, Rochi Saurabh, Alessia Maria Sbaraglia, Jovan Schanzenbacher, Carolin Schmidt, Leon F. Schmidt-Jimènez, Christian Willi Scheiner, Mareile Schlotfeldt, Nora Schoell, Farbod Bahreini, Sarah Stenger

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ALMA Observations of Massive Clouds in the Central Molecular Zone: External-pressure-confined Dense Cores and Salpeter-like Core Mass Functions by Zhenying Zhang, Xing Lu, Tie Liu, Sheng-Li Qin, Adam Ginsburg, Yu Cheng, Hauyu Baobab Liu, Daniel L. Walker, Xindi Tang, Shanghuo Li, Qizhou Zhang, Thushara Pillai, Jens Kauffmann, Cara Battersby, Siyi Feng, Suinan Zhang, Qi-Lao Gu, Fengwei Xu, Wenyu Jiao, Xunchuan Liu, Li Chen, Qiu-yi Luo, Xiaofeng Mai, Zi-yang Li, Dongting Yang, Xianjin Shen, Meizhu Liu, Zhiqiang Shen

“…We present Atacama Large Millimeter/submillimeter Array Band 6 (1.3 mm) observations of dense cores in three massive molecular clouds within the central molecular zone (CMZ) of the Milky Way, including the Dust Ridge cloud e, Sgr C, and the 20 km s ^−1 cloud, at a spatial resolution of 2000 au. …”
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Cortical AAV-CNTF Gene Therapy Combined with Intraspinal Mesenchymal Precursor Cell Transplantation Promotes Functional and Morphological Outcomes after Spinal Cord Injury in Adult... by Stuart I. Hodgetts, Jun Han Yoon, Alysia Fogliani, Emmanuel A. Akinpelu, Danii Baron-Heeris, Imke G. J. Houwers, Lachlan P. G. Wheeler, Bernadette T. Majda, Sreya Santhakumar, Sarah J. Lovett, Emma Duce, Margaret A. Pollett, Tylie M. Wiseman, Brooke Fehily, Alan R. Harvey

“…Ciliary neurotrophic factor (CNTF) promotes survival and enhances long-distance regeneration of injured axons in parts of the adult CNS. …”
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Health and social care use, costs, and satisfaction among key workers accessing Resilience Hub support during the COVID-19 pandemic by Aleix Rowlandson, Filippo Varese, Linda M. Davies, Paul French, Kate Allsopp, Lesley-Anne Carter, Daniel Hind, Katherine McGuirk, Alan Barrett, Gita Bhutani, Fay Huntley, Joanne Jordan, May Sarsam, Hein Ten Cate, Holly Walker, Ruth Watson, Jack Wilkinson, Jenni Willbourn, Gemma E. Shields

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Piloting an automated query and scoring system to facilitate APDS patient identification from health systems by Amy M. FitzPatrick, Aaron T. Chin, Sharon Nirenberg, Charlotte Cunningham-Rundles, Keith Sacco, Jesse Perlmutter, Joseph F. Dasso, Athanasios Tsalatsanis, Jay Maru, Jessica Creech, Jolan E. Walter, Nicholas Hartog, Neema Izadi, Mandy Palmucci, Manish J. Butte, Klaus Loewy, Anurag Relan, Nicholas L. Rider

“…We ran the query across EHRs from 7 large, US-based medical centers encompassing approximately 17 million patients. …”
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Tailored topotactic chemistry unlocks heterostructures of magnetic intercalation compounds by Samra Husremović, Oscar Gonzalez, Berit H. Goodge, Lilia S. Xie, Zhizhi Kong, Wanlin Zhang, Sae Hee Ryu, Stephanie M. Ribet, Shannon S. Fender, Karen C. Bustillo, Chengyu Song, Jim Ciston, Takashi Taniguchi, Kenji Watanabe, Colin Ophus, Chris Jozwiak, Aaron Bostwick, Eli Rotenberg, D. Kwabena Bediako

“…However, crystallographic incommensurability and atomic-scale interfacial disorder can severely limit the types of materials amenable to this strategy, as well as the performance of these systems. …”
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Review of Interventional Therapies for Refractory Pediatric Migraine by Jacquelin Peck, Justin Zeien, Megha Patel, Elyse M. Cornett, Amnon A. Berger, Jamal Hasoon, Hisham Kassem, Jai Won Jung, Giovanni F. Ramírez, Paola Colon Fugueroa, Neil R. Singhal, Jaehong Song, Adam M. Kaye, Alan D. Kaye, Sarang S. Koushik, Natalie H. Strand, Latha Ganti

“…Blocking the sphenopalatine ganglion can be achieved through nasal approach, and achieves a similar action by blocking the entire ganglion. …”
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Heterogeneity of Intermediate Care Organization Within a Single Healthcare System by Aaron S. Case, MD, MHS, Chad H. Hochberg, MD, MHS, Binu Koirala, PhD, MGS, BSN, RN, Eleni Flanagan, DNP, MBA, Souvik Chatterjee, MD, William N. Checkley, MD, PhD, Ayse P. Gurses, PhD, MS, MPH, David N. Hager, MD, PhD

“…Six IC settings (50%) were embedded within acute care wards, four (33%) were stand-alone units, and two (17%) were embedded within an ICU. …”
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CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair by Luc Provencher, Wilson Nartey, Peter M. Brownlee, Austin W. Atkins, Jean-Philippe Gagné, Lou Baudrier, Nicholas S. Y. Ting, Cortt G. Piett, Shujuan Fang, Dustin D. Pearson, Shaun Moore, Pierre Billon, Zachary D. Nagel, Guy G. Poirier, Gareth J. Williams, Aaron A. Goodarzi

“…Abstract To tolerate oxidative stress, cells enable DNA repair responses often sensitive to poly(ADP-ribose) (PAR) polymerase 1 and 2 (PARP1/2) inhibition—an intervention effective against cancers lacking BRCA1/2. Here, we demonstrate that mutating the CHD6 chromatin remodeler sensitizes cells to PARP1/2 inhibitors in a manner distinct from BRCA1, and that CHD6 recruitment to DNA damage requires cooperation between PAR- and DNA-binding domains essential for nucleosome sliding activity. …”
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Acute Myocardial Infarction Reduces Respiration in Rat Cardiac Fibers, despite Adipose Tissue Mesenchymal Stromal Cell Transplant by Camila I. Irion, Eduarda L. Martins, Michelle L. A. Christie, Cherley B. V. de Andrade, Alan C. N. de Moraes, Raphaela P. Ferreira, Cibele F. Pimentel, Grazielle D. Suhett, Antonio Carlos C. de Carvalho, Rafael S. Lindoso, Adalberto Vieyra, Antonio Galina, Regina C. S. Goldenberg

“…Female rats were subjected to AMI by permanent left anterior descending coronary (LAD) ligation and were then treated with AD-MSCs or PBS in the border zone (BZ). …”
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