Focal therapy of prostate cancer: Use of artificial intelligence to define tumour volume and predict treatment outcomes by Wayne G. Brisbane, Alan M. Priester, Anissa V. Nguyen, Mark Topoozian, Sakina Mota, Merdie K. Delfin, Samantha Gonzalez, Kyla P. Grunden, Shannon Richardson, Shyam Natarajan, Leonard S. Marks

“…Secondary outcomes were MRGB at 18 months and failure‐free survival, that is, lack of metastasis or salvage whole gland therapy. …”
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Rare Mental Health Disorders Affecting Urologic Care: A Comprehensive Review by Abrahim N. Razzak, Nicholas A. Orlando, Alexis Angelette, Vinay Kumar, Danyon J. Anderson, Jamal Hasoon, Omar Viswanath, Alan D. Kaye, Joseph S. Fitz-Gerald, Nazih Khater, Ivan Urits

“…Additionally, as these mental health illnesses may carry a rare incidence compared to other well-known mental health illness such as generalized depression or generalized anxiety disorder, we have found that the lack of provisions and recognition of the diseases can prolong the timeline for diagnosis and lead to an increased cost in both healthcare and quality of life of patients with these mental health illnesses. …”
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Production, Transport, and Destruction of Dust in the Kuiper Belt: The Effects of Refractory and Volatile Grain Compositions by Thomas Corbett, Alex Doner, Mihály Horányi, Pontus Brandt, Will Grundy, Carey M. Lisse, Joel Parker, Lowell Peltier, Andrew R. Poppe, Kelsi N. Singer, S. Alan Stern, Anne J. Verbiscer

“…The Venetia Burney Student Dust Counter (SDC) on board the New Horizons spacecraft measures the spatial and size distributions of dust along its trajectory. Models based on early SDC measurements predicted a peak dust number density at a heliocentric distance of ∼40 au, followed by a rapid decline. …”
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Canadian Thoracic Society Recommendations for Management of Chronic Obstructive Pulmonary Disease – 2003 by Denis E O’donnell, Shawn Aaron, Jean Bourbeau, Paul Hernandez, Darcy D Marciniuk, Meyer Balter, Gordon Ford, Andre Gervais, Roger Goldstein, Rick Hodder, Francois Maltais, Jeremy Road

“…Long acting anticholinergics and beta2-agonist inhalers should be prescribed for patients who remain symptomatic despite short-acting bronchodilator therapy. …”
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Mutational Profile and Retinal Phenotypes of PCARE-Related Cone-Rod Dystrophies in a Mexican Cohort by Víctor R. López-Rodríguez, Rocío Arce-González, Alan Martínez-Aguilar, Carlos E. Rodríguez-López, Sergio Groman-Lupa, M. Isabel Neria-González, Genaro Rodríguez-Uribe, Juan C. Zenteno

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Ecological-based insights into bat populations in the Yucatán Peninsula under a One Health approach: coexistence or biophobia by Ma. Fernanda Sánchez-Soto, Osiris Gaona, Ricardo Mercado-Juárez, Ricardo Mercado-Juárez, Alfredo Yanez-Montalvo, Arit de León-Lorenzana, Gabriela Borja-Martínez, Gabriela Borja-Martínez, Daniela Zaldívar, Stephany Rodríguez-González, Erika N. Hernández-Villegas, Andres Moreira-Soto, Jan Felix Drexler, Gerardo Suzán, Ella Vázquez-Domínguez, Luisa I. Falcón

“…Findings suggest that land use differences in the YP are a factor affecting bat diversity, as well as bat microbiome diversity. …”
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In-situ probing of the Fischer-Tropsch reaction on Co single crystal surfaces up to 1 bar by Patrick Lömker, David Degerman, Christopher M. Goodwin, Mikhail Shipilin, Peter Amann, Gabriel L. S. Rodrigues, Fernando Garcia-Martinez, Raffael Rameshan, Jörgen Gladh, Hsin-Yi Wang, Markus Soldemo, Alexander Holm, Steffen Tober, Jan-Christian Schober, Leon Jacobse, Vedran Vonk, Robert Gleißner, Heshmat Noei, Zoltan Hegedues, Andreas Stierle, Christoph Schlueter, Anders Nilsson

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Experiencia en DAC cardiaca en la Comunidad Valenciana: programa de extracción cardiaca extrahospitalaria by Audelio Guevara-Bonilla, Eduardo Tébar-Botí, Claudia Aguirre-Ramón, Alexandra Merino-Orozco, Carlos Domínguez-Massa, Manuel Pérez-Guillén, Ana Bel-Mínguez, Salvador Torregrosa-Puerta, Tomás Heredia-Cambra, Alejandro Rincón-Almanza, María J. Dalmau-Sorli, Iván Martín González, Francisco J. Valera Martínez, Ana Tur-Alonso, Juan B. Martínez León

“…Para ello se ha implementado un protocolo extracción cardiaca extrahospitalaria dentro de la Comunidad Valenciana. Material y método: Desde noviembre de 2022 a abril de 2024 se han realizado 21 valoraciones cardiacas en el contexto de la DAC.Criterios de inclusión: donante < 55 años; consentimiento familiar de donación; previsión de tiempo de isquemia caliente funcional < 30 min.Criterios de exclusión del donante, los propios de una donación cardiaca más: infusión de adrenalina; infusión de dobutamina; infusión de noradrenalina > 0,3 μg/kg/min.Es un estudio descriptivo retrospectivo. …”
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Population Genomics Reveals Elevated Inbreeding and Accumulation of Deleterious Mutations in White Raccoon Dogs by Yinping Tian, Yu Lin, Yue Ma, Jiayi Li, Sunil Kumar Sahu, Jiale Fan, Chen Lin, Zhiang Li, Minhui Shi, Fengping He, Lianduo Bai, Yuan Fu, Zhangwen Deng, Huabing Guo, Haimeng Li, Qiye Li, Yanchun Xu, Tianming Lan, Zhijun Hou, Yanling Xia, Shuhui Yang

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NKAPL facilitates transcription pause-release and bridges elongation to initiation during meiosis exit by Zhenlong Kang, Chen Xu, Shuai Lu, Jie Gong, Ruoyu Yan, Gan Luo, Yuanyuan Wang, Qing He, Yifei Wu, Yitong Yan, Baomei Qian, Shenglin Han, Zhiwen Bu, Jinwen Zhang, Xian Xia, Liang Chen, Zhibin Hu, Mingyan Lin, Zheng Sun, Yayun Gu, Lan Ye

“…NKAPL binds to promoter-associated nascent transcripts and co-localizes with DNA-RNA hybrid R-loop structures at GAA-rich loci to enhance R-loop formation and facilitate Pol II pause-release. …”
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Utilizing wastewater surveillance to model behavioural responses and prevent healthcare overload during “Disease X” outbreaks by Wenxiu Chen, Wei An, Chen Wang, Qun Gao, Chunzhen Wang, Lan Zhang, Xiao Zhang, Song Tang, Jianxin Zhang, Lixin Yu, Peng Wang, Dan Gao, Zhe Wang, Wenhui Gao, Zhe Tian, Yu Zhang, Wai-yin Ng, Tong Zhang, Ho-kwong Chui, Jianying Hu, Min Yang

“…Additionally, this approach can be applied to managing future outbreaks of unknown viruses or “Disease X”.…”
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Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOk... by Narayanaswamy Venketasubramanian, Deidre Anne De Silva, Christopher P L H Chen, Cyrus G Escabillas, John Harold Hiyadan, Johnny K Lokin, Romulo U Esagunde, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Carol Huilian Tham

“…Background MLC1501, consisting of four herbs, that is, Radix Astragali, Radix Angelicae sinensis, Rhizoma Chuanxiong, Radix Polygalae, has the same pharmacological properties as its precursors MLC601 and MLC901 which contain extracts of nine herbs and showed neuroprotective, anti-inflammatory and neurorestorative properties in non-clinical models, as well as clinical benefits in improving functional and neurological recovery after brain injuries.Aims To determine the efficacy of MLC1501 on motor recovery as measured by Fugl-Meyer motor Assessment (FMA) total score at 24 weeks in patients with ischaemic stroke (IS).Design A total of 300 patients aged &gt;18 years, diagnosed with IS in the prior 2–10 days, with National Institute of Health Stroke Scale (NIHSS) total score of 8–18 and a combined score of ≥3 on NIHSS motor items 5A, 5B, 6A and/or 6B, will be randomised in a 1:1:1 ratio to receive oral placebo, MLC1501 low dose or MLC1501 high dose for 6 months. …”
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Arthralgia and Extraintestinal Manifestations in Crohn’s Disease Elevate the Risk of IBD-Related Arthritis over Sacroiliitis by Ivan Giovannini, Nicola Cabas, Marco Marino, Annarita Tullio, Ilaria Tinazzi, Angela Variola, Carmelo Cicciò, Fabro Cinzia, Berretti Debora, Chiara Zuiani, Rossano Girometti, Luca Quartuccio, Alen Zabotti, Lorenzo Cereser

“…Magnetic resonance enterography (MRE) is used to assess small bowel disease involvement in Crohn’s disease (CD) and can detect signs of sacroiliitis in up to 23.5% of patients. …”
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Hurricane Effects on a Shallow Lake Ecosystem and Its Response to a Controlled Manipulation of Water Level by Karl E. Havens, Kang-Ren Jin, Andrew J. Rodusky, Bruce Sharfstein, Mark A. Brady, Therese L. East, Nenad Iricanin, R. Thomas James, Matthew C. Harwell, Alan D. Steinman

“…These strong velocities were associated with large-scale uplifting and horizontal transport of fine-grained sediments from the lake bottom. …”
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Meniscus Ripstop Stitches: A Useful Technique for Arthroscopic Repair of Challenging Radial Tears of the Meniscus by Fabien Meta, M.D., Alexander C. Hayden, M.D., Xuankang Pan, B.S., Mario Hevesi, M.D., Ph.D., Adam J. Tagliero, M.D., Aaron J. Krych, M.D.

“…Radial meniscal tears can be challenging to address and require advanced arthroscopic techniques for satisfactory repair. …”
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Historical Pathways for Opioid Addiction, Withdrawal with Traditional and Alternative Treatment Options with Ketamine, Cannabinoids, and Noribogaine: A Narrative Review by Amber N. Edinoff, Natalie W. Wu, Catherine A. Nix, Bryce Bonin, Rama Mouhaffel, Stephen Vining, William Gibson, Elyse M. Cornett, Kevin S. Murnane, Adam M. Kaye, Alan D. Kaye

“…Currently, the primary pharmacotherapies used to treat opioid addiction over the long term are the opioid antagonist naltrexone, the partial-agonist buprenorphine, and the full agonist methadone. …”
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Gestão do conhecimento em instituições de ensino superior: um estudo na Universidade Federal Rural do Semiárido by Priscilla Even Alves Braga, Carlos Alano Soares de Almeida, Adriana Martins de Oliveira, Maria de Fátima Nóbrega Barbosa, Francisco Carlos Carvalho de Melo, Maria Helena da Costa Silva

“…Conheceu-se ainda que as dificuldades apresentadas são consequência da transmissão do conhecimento realizada em grande parte por meio da socialização (de conhecimento tácito para tácito). …”
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Effect of sugarcane bagasse biochar on soybean germination and initial growth by Lorrana Zelia Martins de Souza, Halax Duart Martins Silva, Giovanni Uema Alcantara, Bruna Cristina Pinto, Adriana Duneya Diaz Carillo, Osania Emerenciano Ferreira, Gustavo Henrique Gravatim Costa, Alan Machado

“…The biochar exhibited a low O/C ratio (0.18) and an irregular porous surface, which promoted improvements in the soil’s physical, chemical, and biological attributes. …”
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