Scalable Manufacturing Method for Model Protein-Loaded PLGA Nanoparticles: Biocompatibility, Trafficking and Release Properties by Selin Akpinar Adscheid, Marta Rojas-Rodríguez, Salma M. Abdel-Hafez, Francesco S. Pavone, Marc Schneider, Akif E. Türeli, Martino Calamai, Nazende Günday-Türeli

“…Among DDSs, polymeric nanoparticles (NPs), particularly poly(lactic-co-glycolic acid) (PLGA) NPs, hold an outstanding position due to their biocompatible and biodegradable qualities. …”
Get full text

Optimizing Bacterial Protectant Composition to Enhance Baijiu Yeast Survival and Productivity During Spray Drying by Jingyu Li, Fengkui Xiong, Zhongbin Liu, Jia Zheng, Guangzhong Hu, Zheng Feng

“…The results showed that the addition of “TGase-treated soybean isolate protein (SPI) + lactic protein (LP)” as an in vitro bacterial protectant and “14.15% trehalose + 7.10% maltose + 14.04% sucrose” TGase treatment can promote the cross-linking of protective proteins, reduce the distance between <i>MSJA</i> bacteria and protective proteins, and increase the glass transition temperature to enhance the protective effect of protective proteins, so as to improve the survival rate of <i>MSJA</i> during spray drying.…”
Get full text

Extracorporeal membrane oxygenation for Chinese neonates with severe respiratory and cardiac failure by Xiao-Juan Zhang, Ying-Yue Liu, Hui Wang, Xiao-Yang Hong

“…The survivors exhibited a significant reduction in lactic acid levels within the first 24 h. In the 15 successful weaning neonates, four neonates died at the end of the study; one was for the cardiac function failure; two were for the respiratory failure; one was given up for Bipedal necrosis; the other 11 neonates were successful discharge. …”
Get full text

Quality of Cattle Meat and Its Compositional Constituents by Umer Seid Geletu, Munera Ahmednur Usmael, Yesihak Yusuf Mummed, Abdulmuen Mohammed Ibrahim

“…Meat quality can be evaluated according to the following parameters: pH, amount of lactic acid, volatile fatty acids, bounded water, solubility of proteins, color, and tenderness. …”
Get full text

Types of dietary sugars and carbohydrates, cardiometabolic risk factors, and risk of diabetes: a cohort study from the general Danish population by Marta Trius-Soler, Maja Bramming, Majken K. Jensen, Janne S. Tolstrup, Marta Guasch-Ferré

“…This study aims to examine the prospective association between types of dietary carbohydrates (fiber, starch, total sugar, glucose, fructose, lactose, maltose, and added sugar) and the risk of diabetes. …”
Get full text

Research note: Protective effects of compound mycotoxin detoxifier in broiler chicken fed aflatoxins-contaminated diets by Kourosh Gholami Ahmadabadi, Mahsa Rahimi, Hamid Raei, Reza Majedifar, Mohammad Amir Karimi Torshizi

“…Feeding broilers with AFs decreased villus height, villus width, and crypt depth compared to the NC (P < 0.05). The increasing lactic acid bacteria population in HCTB was recorded compared to the PC (P < 0.05). …”
Get full text

Chemical Fingerprint Analysis for Discovering Markers and Identifying Saussurea involucrata by HPLC Coupled with OPLS-DA by Qingdong Ma, Xiaoxiang Chen, Ke Zhang, Dahong Yao, Lu Yang, Hangyu Wang, Santai Bulemasi, Jian Huang, Jinhui Wang

“…Among them, peaks 9, 11, 16 (zaluzanin C), and 18 (dehydrocostus lactone) have been identified as fingerprint markers of S. involucrata via S-plots and VIP values (>1). …”
Get full text

Metformin and Probiotics Interplay in Amelioration of Ethanol-Induced Oxidative Stress and Inflammatory Response in an In Vitro and In Vivo Model of Hepatic Injury by Farhin Patel, Kirti Parwani, Dhara Patel, Palash Mandal

“…Therefore, we investigated the effectiveness of combination therapy using a mixture of eight strains of lactic acid-producing bacteria, commercialized as Visbiome® (V) and Met in preventing the ethanol-induced hepatic injury using in vitro and in vivo models. …”
Get full text

Effect of probiotics on the growth, blood profile, and nutritional-metabolic profile of feedlot cattle by Flavia I. Mansilla, María C. Aristimuño Ficoseco, María H. Miranda, Marcela D’Urso Villar, Graciela M. Vignolo, María E. F. Nader-Macías

“…In addition, the multistrain probiotic formulation exhibited higher numbers of cultivable lactic acid bacteria and a slight decrease in the number of enterobacteria in feces at the end of the trial. …”
Get full text

Probiotics Fermented Bitter Melon Juice as Promising Complementary Agent for Diabetes Type 2: Study on Animal Model by Laksmi Hartajanie, S. Fatimah-Muis, K. Heri-Nugroho HS, Ign Riwanto, M. Sulchan

“…Bitter melon (Momordica charantia/MC) contains charantin that has antidiabetic properties as an α-glucosidase inhibitor and antioxidative properties. Lactic acid fermentation using Lactobacillus fermentum LLB3 increased its antioxidative properties. …”
Get full text

Incorporation of recombinant proteins into extracellular vesicles by Lactococcus cremoris by Tina Vida Plavec, Kristina Žagar Soderžnik, Giulia Della Pelle, Špela Zupančič, Robert Vidmar, Aleš Berlec

“…This study aimed to investigate the production of EVs by lactic acid bacterium Lactococcus cremoris NZ9000 and to examine the impact of recombinant protein expression on their formation and protein content. …”
Get full text

Carbon Monoxide Poisoning with Neurological, Ocular, and Myocardial Damage: A Case Report by Duc Nguyen, Sinh Nguyen, Anh Lam

“…CO has a high affinity with hemoglobin because it reduces oxygen transport causing tissue hypoxia, lactic acidosis, and cell death.Case report: A 32-year-old female patient entered Poison Control Center of Bach Mai Hospital, Ha Noi, Vietnam, because of decreased consciousness, loss of vision in the right eye. …”
Get full text

Exploring Anti-Breast Cancer Effects of Live Pediococcus acidilactici and Its Cell-Free Supernatant Isolated from Human Breast Milk by Naa N. Adumuah, Jude T. Quarshie, Harry Danwonno, Anastasia R. Aikins, Elmer N. Ametefe

“…Thus, this study aimed at exploring the effect of lactic acid bacteria isolated from human breast milk on MDA-MB 231 breast cancer cells. …”
Get full text

Impact of Commercial Protective Culture on Manouri PDO Cheese by Thomas Bintsis, Maria A. Kyritsi

“…The application of the CPC resulted in cheeses with higher pH than the control cheese, probably due to the growth of acidifying lactic acid bacteria in the microbiota of the S2 and S3 cheeses. …”
Get full text

Hirelings and Laborers: Biblical Parable in Blake’s Milton by Leslie Tannenbaum

“…Dans son poème, Blake prend comme point de départ la distinction biblique de Milton entre le vrai travailleur et le mercenaire, et fait de cette distinction le fondement de l’énigmatique Chant du Barde qui déclenche l’action du poème. Le Chant du Barde est, entre autres, une parabole concernant le travail qui rejoint la plupart des préoccupations exprimées dans la Bible ou développées par Milton. …”
Get full text

IL-6-mediated MHC class II induction on RIN-5AH insulinoma cells by IFN-γ occurs via the G-protein pathway by S. Vassiliadis, G. K. Papadopoulos

“…Signal transduction analysis reveals that IL-6-induced MHC class II expression is specifically mediated by the G-protein system (activation of p21ras by IL-6) since mevalonic acid lactone (a Gprotein inhibitor) abolishes the action of IL-6. …”
Get full text

Severe central nervous system injury in 9 children with COVID-19 by Peipei Zhang, Meiyun Xin, Yingge Bai, Xueyun Ren, Na Li

“…Most of the children had elevated interleukin-6 (100%), lactic acid (100%), alanine transaminase (87.5%), aspartate transaminase (87.5%), creatine kinase MB (87.5%), and lactate dehydrogenase (85.7%) levels. …”
Get full text

Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer by Abhishek Chauhan, Hemant Joshi, Divya Kandari, Diwakar Aggarwal, Ritu Chauhan, Hardeep Singh Tuli, Arpit Mehrotra, Abhilasha Sood, Ujjawal Sharma, Darin Mansor Mathkor, Shafiul Haque, Naveen Chandra Joshi, Laurent Dufossé

“…Background: Oridonin, a diterpenoid lactone derived from medicinal plants, has drawn considerable attention due to its therapeutic potential, particularly its anticancer properties. …”
Get full text

ACCREDIT: Validation of clinical score for progression of COVID-19 while hospitalized by Vinicius Lins Costa Ok Melo, Pedro Emmanuel Alvarenga Americano do Brasil, PhD

“…After model development and cross-validation, the Random Forest regression was considered the best approach, and the following eight predictors were retained: D-dimer, Urea, Charlson comorbidity index, pulse oximetry, respiratory frequency, Lactic Dehydrogenase, RDW, and Radiologic RALE score. …”
Get full text

The quality and technological parameters of milk obtained from dairy cows with subclinical mastitis by Magdalena Zalewska, Paulina Brzozowska, Magdalena Rzewuska, Ewelina Kawecka-Grochocka, Daria M. Urbańska, Tomasz Sakowski, Emilia Bagnicka

“…Bacterial contamination did not appear to significantly affect the yield of milk or its main components, namely protein, casein, lactose, fat, TS, solid nonfat, free fatty acid, or citric acid. …”
Get full text