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  1. 721

    G-quadruplex-forming small RNA inhibits coronavirus and influenza A virus replication by Ryoya Sekine, Kouki Takeda, Tsukasa Suenaga, Satsuki Tsuno, Takumi Kaiya, Maki Kiso, Seiya Yamayoshi, Yoshihide Takaku, Shiho Ohno, Yoshiki Yamaguchi, Seiichi Nishizawa, Kazuhiro Sumitomo, Kazufumi Ikuta, Teru Kanda, Yoshihiro Kawaoka, Hidekazu Nishimura, Shusuke Kuge

    Published 2025-01-01
    “…Abstract Future pandemic threats may be caused by novel coronaviruses and influenza A viruses. Here we show that when directly added to a cell culture, 12mer guanine RNA (G12) and its phosphorothioate-linked derivatives (G12(S)), rapidly entered cytoplasm and suppressed the propagation of human coronaviruses and influenza A viruses to between 1/100 and nearly 1/1000 of normal virus infectivity without cellular toxicity and induction of innate immunity. …”
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  2. 722

    Preparation of specific components of Elisa test-system for detection of Schmallenberg desease virus antigens by O. G. Gubenko, O. P. Bjadovskaya, S. V. Kononova, Yu. Yu. Babin, N. A. Soloukhina, A. V. Kononov

    Published 2018-04-01
    “…Preparation of purified and concentrated antigens of Schmallenberg disease virus as well as specific hyperimmune sera in laboratory animals used for the development of indirect sandwich enzyme-linked immunosorbent assay (ELISA) is described in the paper.…”
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    Comparative Evaluation of Permissiveness to Dengue Virus Serotype 2 Infection in Primary Rodent Macrophages by Jeanette Prada-Arismendy, Verónica Rincón, Jaime E. Castellanos

    Published 2012-01-01
    “…Infection with dengue virus presents a broad clinical spectrum, which can range from asymptomatic cases to severe cases that are characterised by haemorrhagic syndrome and/or shock. …”
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    Immunomodulatory effect of hepatitis B virus (HBV) antigens and MRSA antigens on immune response by Entidhar A. Hadi, Mohammad Abd-Kadhum Al-Saadi, Kaiser N. Madlum

    Published 2024-01-01
    “…Objectives: This study aimed to illustrate the immune response of purified human peripheral blood mononuclear cells against somatic antigens of methicillin-resistant S. aureus (MRSA) and to study the immunomodulatory effect of hepatitis B virus (HBV) antigens on this immune response. Materials and Methods: A case–control study was applied on 75 peripheral blood mononuclear cells (PBMCs) samples. …”
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    Antiviral effect of polyphenol rich plant extracts on herpes simplex virus type 1 by Sayed A. El-Toumy, Josline Y. Salib, Walaa A. El-Kashak, Christel Marty, Gilles Bedoux, Nathalie Bourgougnon

    Published 2018-03-01
    “…The antiviral activity against Herpes Simplex Virus type 1 (HSV-1) was done on Vero cell lines by cell viability. …”
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    SERINC5 counters retroviruses and non-retroviruses by Jinghua Yu, Jinghua Yu, Jinghua Yu, Chunyu Liu, Xinglong Qu, Xinglin Gao, Yue Liu

    Published 2025-01-01
    Subjects: “…human immunodeficiency virus 1…”
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