What was Killing Babies in Ipswich Between 1872 and 1909? by Eilidh Garrett, Alice Reid

“…While water-food borne diseases killed large numbers in the summer months, it was the ever-present airborne diseases which carried off a greater number of small victims. …”
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SOMATIC AND PSYCHIATRIC MORBIDITY OF ELDERLY DRIVERS KILLED IN MOTOR VEHICLE ACCIDENTS IN FINLAND DURING 22-YEAR FOLLOW-UP by JENNY TYNI, PIRKKO RIIPINEN, HELINÄ HAKKO, NIINA SIHVOLA, LIISA KANTOJÄRVI

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Does a biological invasion modify host immune responses to parasite infection? by Gregory P. Brown, Richard Shine, Lee A. Rollins

“…Infected toads also exhibited lower bacteria-killing ability, perhaps reflecting a trade-off of resources towards defences that are more specifically anthelminthic. …”
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Concentration-dependent effects of immunomodulatory cocktails on the generation of leukemia-derived dendritic cells, DCleu mediated T-cell activation and on-target/off-tumor toxici... by Hazal Aslan Rejeski, Hazal Aslan Rejeski, Anne Hartz, Anne Hartz, Elias Rackl, Elias Rackl, Lin Li, Lin Li, Christoph Schwepcke, Christoph Schwepcke, Kai Rejeski, Kai Rejeski, Christoph Schmid, Christoph Schmid, Andreas Rank, Andreas Rank, Jörg Schmohl, Doris Kraemer, Peter Bojko, Helga Maria Schmetzer, Helga Maria Schmetzer

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Off-the-shelf CAR-NK cells targeting immunogenic cell death marker ERp57 execute robust antitumor activity and have a synergistic effect with ICD inducer oxaliplatin by Jichao Sun, Dinglan Wu, Liuhai Zheng, Huifang Wang, Jihao Zhou, Guangwei Shi, Jingbo Ma, Yuke Jiang, Zhiyu Dong, Jiexuan Li, Yuan-Qiao He, Chengchao Xu, Zhijie Li, Jigang Wang

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Pan-caspase inhibitors induce secretion of HIV-1 latency reversal agent lymphotoxin-alpha from cytokine-primed NK cells by Zamaneh Hajikhezri, Ioannis Zygouras, Anders Sönnerborg, Robert van Domselaar

“…Abstract The persistence of HIV-1 latency reservoirs in CD4+ T cells is a significant obstacle for curing HIV-1. Shock-and-kill strategies, which aim to reactivate latent HIV-1 followed by cytotoxic clearance, have shown limited success in vivo due to insufficient efficacy of latency reversal agents (LRAs) and off-target effects. …”
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Passive Outdoor Host Seeking Device (POHD): Designing and Evaluation against Outdoor Biting Malaria Vectors by Stella T. Kessy, Ladslaus L. Mnyone, Bruno A. Nyundo, Issa N. Lyimo

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Toxicity Assessment of the Xanthid Crab Demania cultripes from Cebu Island, Philippines by Manabu Asakawa, Gloria Gomez-Delan, Shintaro Tsuruda, Michitaka Shimomura, Yasuo Shida, Shigeto Taniyama, Mercy Barte-Quilantang, Jo Shindo

“…The activity was expressed in mouse unit (MU) being defined as the amount of TTX to kill a 20 g ddY male mice in 30 min after i.p. injection. …”
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Biochemical, ecological and molecular characterization of Xenorhabdus anantnagensis associated with Steinernema anantnagense from India: evaluating nematode efficacy against Helico... by Krishnapriya Okram, Aashaq Hussain Bhat, Ladoi Drema

“…The strain KP_CU could kill the wax moth larvae with 38, 16 and 9 IJs at 24, 36 and 48 h, respectively. …”
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Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen by Yu-Chan Chih, Amelie C. Dietsch, Philipp Koopmann, Xiujian Ma, Dennis A. Agardy, Binghao Zhao, Alice De Roia, Alexandros Kourtesakis, Michael Kilian, Christopher Krämer, Abigail K. Suwala, Miriam Stenzinger, Halvard Boenig, Agnieszka Blum, Victor Murcia Pienkowski, Kuralay Aman, Jonas P. Becker, Henrike Feldmann, Theresa Bunse, Richard Harbottle, Angelika B. Riemer, Hai-Kun Liu, Nima Etminan, Felix Sahm, Miriam Ratliff, Wolfgang Wick, Michael Platten, Edward W. Green, Lukas Bunse

“…The validated vaccine-induced TCR recognizes the endogenously processed antigen without off-target cross-reactivity. PTPRZ1-specific TCR-T (PTPRZ1-TCR-T) kill target cells antigen-specifically, and in murine experimental brain tumors, their combined intravenous and intracerebroventricular administration is efficacious. …”
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Semifield Evaluation of Improved Passive Outdoor Host Seeking Device (POHD) for Outdoor Control of Anopheles arabiensis Mosquitoes by Stella T. Kessy, Bruno A. Nyundo, Ladslaus L. Mnyone, Issa N. Lyimo

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The Use of Granular Cyclopentanone as Alternative to Artificial Source of Carbon Dioxide in Improved Passive Outdoor Host Seeking Device (POHD) by Stella T. Kessy, Bruno A. Nyundo, Ladslaus L. Mnyone, Issa N. Lyimo

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Editorial by Jörg Tremmel, Markus Rutsche

“…This policy paper starts off with a historical overview on how pandemics have afflicted humanity in the past. …”
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Iconic Celebration of Charms and Friendship in Poetry: Fálétí’s “Adébímpé Ọ̀jẹ́dòkun” by Michael Oladejo Afoláyan

“…The second hunter finished off the animal with the shot right on target with a sniper’s propensity. …”
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Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies by Yan-Ruide Li, Ying Fang, Siyue Niu, Yichen Zhu, Yuning Chen, Zibai Lyu, Enbo Zhu, Yanxin Tian, Jie Huang, Valerie Rezek, Scott Kitchen, Tzung Hsiai, Jin J. Zhou, Pin Wang, Wanxing Chai-Ho, Sunmin Park, Christopher S. Seet, Caspian Oliai, Lili Yang

“…Furthermore, CAR-NKT cells synergize with hypomethylating agents, enhancing tumor-killing efficacy. These cells also show minimal off-tumor toxicity, reduced graft-versus-host disease and cytokine release syndrome risks, and resistance to allorejection, highlighting their substantial therapeutic potential for treating myeloid malignancies.…”
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PREVENTING VIOLENCE CRIMES (KIDNAPPING, ARMED ROBBERY, BRIGANDAGE OR COMMUNITY MASSACRE) WITH DRONES: AN EFFECTIVE ALTERNATIVE TO VEHICULAR PATROLS IN NIGERIA by GABRIEL SALIFU, DANIEL OLASUNKANMI OLADAPO

“…In the 21st century, the families off springs are endangered with multiple social vices that range from internet fraud (yahoo yahoo), kidnapping, lesbianism, drug abuse, homosexuality, bestiality, incest, ritual killing and others. …”
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The Molecular Imaging of Natural Killer Cells by Mariya Shapovalova, Sean R. Pyper MD, PhD, Branden S. Moriarity PhD, Aaron M. LeBeau PhD

“…Natural killer cells are cytotoxic lymphocytes that mediate the direct killing of transformed cells with reduced or absent major histocompatibility complex (MHC) and are the effector cells in antibody-dependent cell-mediated cytotoxicity. …”
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Transition Yet Energy Consuming for Tumor Growth Regulated by the Colored Microenvironment by Leiyan Chen, Yan Wang, Qingqing Li, Haohua Wang

“…Moreover, by reconstructing the reaction network from the mesoscopic scale, we further show that AT of multiplicative noise can increase energy consumption, and there exists a trade-off between NS and AT of additive noise. We also show that the energy consumption is monotonically decreasing with increasing the CT but the CS can amplify the difference of this dependence. …”
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Study of an arginine- and tryptophan-rich antimicrobial peptide in peri-implantitis by Qian Zhang, Yalei Jiang, Xiaotong He, Liwei Liu, Xi Zhang

“…Therefore, VR-12 may be a good option for both warding off and treatmenting peri-implantitis.…”
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Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy by Amelia C. McCue, Stephen J. Demarest, Karen J. Froning, Michael J. Hickey, Stephen Antonysamy, Brian Kuhlman

“…We demonstrate with binding experiments and in vitro T-cell activation and killing assays that our designed prodrug TCE is capable of tumor-selective T-cell activity that is dependent upon MMP-2. …”
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