Prevalence and Characterization of Psychological Trauma in Patients with Fibromyalgia: A Cross-Sectional Study by Itxaso Gardoki-Souto, Diego Redolar-Ripoll, Marta Fontana, Bridget Hogg, María José Castro, Josep M. Blanch, Fabiola Ojeda, Aleix Solanes, Joaquim Radua, Alicia Valiente-Gómez, Roser Cirici, Víctor Pérez, Benedikt L. Amann, Ana Moreno-Alcázar

“…Traumatic events predict both poor quality of life and a level of pain in adulthood. All patients showed clinically relevant levels of anxiety, depression, insomnia, suicidal thoughts, and pain, as well as somatic comorbidities and poor quality of life. …”
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Curve progression in non-surgically treated patients with idiopathic scoliosis: a cohort study with 40-year follow-up by Casper Dragsted, Lærke Ragborg, Søren Ohrt-Nisse, Thomas Andersen, Martin Gehrchen, Benny Dahl

“…Results: Mean follow-up was 41 years (standard deviation [SD] 2.5 years). 21 patients underwent surgery in adolescence or early adulthood leaving 70 patients for analysis of curve progression, of whom 61 had complete radiographs. …”
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Optimal Adaptation Period for Metabolic Cage Experiments in Mice at Different Developmental Stages by TAN He, YANG Xiaohui, ZHANG Daxiu, WANG Guicheng

“…Methods A total of 80 male C57BL/6J mice at three developmental stages (weaning period M1, adolescent M2, and adulthood M3) were subjected to a 7-day metabolic cage experiment. …”
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Brief exposure to (-) THC affects zebrafish embryonic locomotion with effects that persist into the next generation by Md Ruhul Amin, Lakhan Khara, Joshua Szaszkiewicz, Andrew M. Kim, Trevor J. Hamilton, Declan W. Ali

“…Prenatal exposure to THC can alter neural and behavioral development, but it is unknown how exposure to (-) trans-THC ((-)THC) during very early stages of development impacts fetal growth and movement, and whether effects persist to adulthood, or into the next generation. Here we exposed zebrafish (Danio rerio) to a single exposure of (-)THC (0.001 mg/L (3.2 nM) to 20 mg/L (63.6 µM), for 5 h) during gastrulation (5.25 hpf to 10.75 hpf) when key neurons involved in locomotion such as the primary motor neurons and Mauthner cell first appear. …”
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How climate change is shaping young people’s health: a participatory, youth co-led study from Bangladesh, Guatemala and Nigeria by Jessie Pinchoff, Karen Austrian, Eno-Obong Etetim, Damilola Babatunde, Eleanor Blomstrom, Sigma Ainul, Toyin Olamide Akomolafe, Brian Medina Carranza, Angel Del Valle

“…Introduction Climate change is shaping adolescent and young people’s (AYP) transitions to adulthood with significant and often compounding effects on their physical and mental health. …”
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Family caregiver frailty in adult congenital heart disease is overlooked: A call to action by Arianna Magon, Serena Francesca Flocco, Laura Schianchi, Massimo Chessa, Daniele Ciofi, Salvatore Angileri, Maddalena De Maria, Gianluca Conte, Silvia Favilli, Cristina Arrigoni, Rosario Caruso

“…The evidence gathered in this regard identifies three key domains affecting FCs: psychological stress and childcare, physical health decline, and the challenges of caregiving during transitions to adulthood. These findings underscore the urgent need for family-centered care models that incorporate tailored frailty assessments and targeted interventions to support FCs throughout their caregiving journey. …”
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Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3 by Han Chu, Qi-Fei Deng, Yuan Fang

“…IntroductionCryptorchidism can damage cells in the cryptorchid testes due to elevated local temperatures, potentially impacting the fertility of the child in adulthood. Research indicates that vitamin D enhances sperm quality in adult males. …”
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Tyrosine hydroxylase of the brain and it’s regulation by glucocorticoids by E. V. Sukhareva, T. S. Kalinina, V. V. Bulygina, N. N. Dygalo

“…Early life stress events can produce long-lasting changes in neurochemistry and behaviors related to monoamine systems, with increased risks of cardiovascular, metabolic, neuroendocrine, psychiatric disorders, generalized anxiety and depression in adulthood. Tyrosine hydroxylase (TH), the key enzyme for catecholamine synthesis, also plays an important role in the activity of the noradrenergic system and may be a target for glucocorticoids during the perinatal programming of physiological functions and behavior. …”
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SOME ASPECTS OF TEETH ERUPTION. A LITERATURE REVIEW by L.V. Smaglyuk, Н.V. Voronkova, A.Y. Karasiunok

“…Altered passive eruption (APE) (also known as delayed passive eruption) occurs when the edge of the gums is incorrectly (occlusively) located on the anatomical crown in adulthood and does not approach the CEJ. The "normal" position of the gingival margin to the CEJ is usually considered to be on or near the CEJ in the fully incised teeth of adults. …”
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Factors Associated with Anemia among Children Aged 6–23 Months Attending Growth Monitoring at Tsitsika Health Center, Wag-Himra Zone, Northeast Ethiopia by Haile Woldie, Yigzaw Kebede, Amare Tariku

“…Anemia during infancy and young childhood period is associated with poor health and impaired cognitive development, leading to reduced academic achievement and earnings potential in their adulthood life. However, there is scarcity of information showing the magnitude of iron deficiency anemia among young children in Ethiopia. …”
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Prevalence and Risk Factors of Childhood Hypertension in Urban-Rural Areas of China: A Cross-Sectional Study by Xiaohua Liang, Lun Xiao, Yetao Luo, Jiapei Xu

“…The increased blood pressure level in children and adolescents is recognized as an essential predictor of adulthood cardiovascular disease. This study aimed to ascertain the prevalence and the urban-rural disparity of childhood hypertension in the southwest of China. …”
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The association of dietary approaches to stop hypertension measured by the food frequency questionnaire with metabolic syndrome and some inflammatory biomarkers in adolescents with... by Maryam Behrooz, Alireza Ostadrahimi, Samaneh Hajjarzadeh, Mirhadi Mousavi, Afshin Ghalegolab Behbahani, Siamak Shiva

“…Adolescent obesity is associated with cardiometabolic risk and metabolic disorders in adolescence and may persist into adulthood. The current study was designed to explore the Dietary Approaches to Stop Hypertension (DASH) in adolescents and its relationship with obesity, insulin resistance, metabolic syndrome (MetS), and some inflammatory biomarkers. …”
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A novel framework to predict ADHD symptoms using irritability in adolescents and young adults with and without ADHD by Saeedeh Komijani, Dipak Ghosal, Manpreet K. Singh, Julie B. Schweitzer, Julie B. Schweitzer, Prerona Mukherjee, Prerona Mukherjee

“…ADHD persists for many into adulthood. While irritability is not a diagnostic symptom of ADHD, temper outbursts and irritable moods are common in individuals with ADHD. …”
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Anxiety, Depression, and Their Related Factors Among Parents/Guardians of Students Affected by Nigerian University Staff Strikes by Patrick Ayi Ewah, Idoo Womboh, Peter Agba Awhen, Felicia Agbor-Obun Dan

“…Results: Most of the participants were in mid-late adulthood (78%) and female (57%). The prevalence of anxiety and depression was 62.1% and 27.6%, respectively. …”
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Implementation of a program to strengthen oral hygiene in patient with cleft deformities: a prospective randomized controlled clinical trial by Camille Boeffard, Justine Loin, Roselyne Clouet, Alexis Gaudin, Pierre Corre, Tony Prud’Homme

“…Cleft patients are treated by a multidisciplinary team that aims to provide comprehensive care from pre- or post-natal diagnosis to early adulthood and the end of growth. We aim to assess, through a single-center, prospective, randomized and controlled clinical trial conducted at the Nantes Cleft Centre, the impact of an enhanced dental program on oral hygiene and dental health in cleft patients. …”
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Edge-centric connectome-genetic markers of bridging factor to comorbidity between depression and anxiety by Zhiyi Chen, Yancheng Tang, Xuerong Liu, Wei Li, Yuanyuan Hu, Bowen Hu, Ting Xu, Rong Zhang, Lei Xia, Jing-Xuan Zhang, Zhibing Xiao, Ji Chen, Zhengzhi Feng, Yuan Zhou, Qinghua He, Jiang Qiu, Xu Lei, Hong Chen, Shaozheng Qin, Tingyong Feng

“…In an independent twin cohort, we found that these patterns were moderately heritable, and identified their genetic connectome-transcriptional markers that were associated with the neurobiological enrichment of vasculature and cerebellar development, particularly during late-childhood-to-young-adulthood periods. Our findings revealed a general factor of bridging symptoms and its neurobiological architectures, which enriched neurogenetic understanding of depression-anxiety comorbidity.…”
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Effects of early neonatal proinflammatory stress on the expression of BDNF transcripts in the brain regions of prepubertal male rats by D. I. Peregud, S. V. Freiman, A. O. Tishkina, L. S. Sokhranyaeva, N. A. Lazareva, M. V. Onufriev, M. Y. Stepanichev, N. V. Gulyaeva

“…Early postnatal proinflammatory stress provokes behavioral impairments in adulthood; however, underlying mechanisms are still elusive. …”
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Mobile health in communication disorders: willingness to use, attitude, advantages, and challenges from the perspective of patients by Taleb Khodaveisi, Hamid Bouraghi, Soheila Saeedi, Marjan Ghazisaeedi, Mohammad-Sadegh Seifpanahi, Shokofeh Ahsanifar, Sara Vafaeeyan

“…Abstract Introduction Communication disorders are one of the most common disorders that, if not treated in childhood, can cause many social, educational, and psychological problems in adulthood. One of the technologies that can be helpful in these disorders is mobile health (m-Health) technology. …”
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Targeting of retrovirus-derived Rtl8a/8b causes late-onset obesity, reduced social response and increased apathy-like behaviour by Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii, Ryuichi Ono, Tsutomu Endo, Hiroshi Kiyonari, Yoshikazu Hirate, Hikaru Ito, Masami Kanai-Azuma, Takashi Kohda, Tomoko Kaneko-Ishino, Fumitoshi Ishino

“…Here, we demonstrate that Rtl8a and Rtl8b play important roles in the brain: their double knockout (DKO) mice not only exhibit reduced social responses and increased apathy-like behaviour, but also become obese from young adulthood, similar to patients with late Prader–Willi syndrome (PWS), a neurodevelopmental genomic imprinting disorder. …”
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Utilities Associated with the Treatment of Growth Hormone Deficiency (GHD): A Time Trade-off (TTO) Study in the UK and Canada by Kirsch S, Butler G, Jensen LDF, Okkels A, Yssing C, Håkan-Bloch J

“…Susan Kirsch,1 Gary Butler,2 Lasse de Fries Jensen,3 Anna Okkels,4 Cecilie Yssing,4 Jonas Håkan-Bloch3 1Department of Pediatric Endocrinology, Hospital for Sick Children, Toronto and Oak Valley Health Hospital, Markham, Ontario, Canada; 2Department of Paediatric Endocrinology, University College London Hospitals, and UCL Great Ormond Street Institute of Child Health, London, UK; 3Novo Nordisk, Søborg, 2860, Denmark; 4EY Godkendt Revisionspartnerselskab, Frederiksberg, 2000, DenmarkCorrespondence: Lasse de Fries Jensen, Novo Nordisk, Vandtårnsvej 108-110, Søborg, 2860, Denmark, Tel +45 34482020, Email LDFJ@novonordisk.comPurpose: Growth hormone deficiency (GHD) causes decreased growth rate in children, resulting in short stature in childhood and adulthood. Daily subcutaneous injections with growth hormone (GH) have been standard treatment. …”
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