Exploring the interaction between the gut microbiota and cyclic adenosine monophosphate-protein kinase A signaling pathway: a potential therapeutic approach for neurodegenerative diseases by Fengcheng Deng, Dan Yang, Lingxi Qing, Yifei Chen, Jilian Zou, Meiling Jia, Qian Wang, Runda Jiang, Lihua Huang

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M2 Macrophages Mediate the Resistance of Gastric Adenocarcinoma Cells to 5-Fluorouracil through the Expression of Integrin β3, Focal Adhesion Kinase, and Cofilin by Daniel Ngabire, Irvine Niyonizigiye, Maheshkumar Prakash Patil, Yeong-Ae Seong, Yong Bae Seo, Gun-Do Kim

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Relationship of the gene pool of the Khants with the peoples of Western Siberia, Cis-Urals and the Altai-Sayan Region according to the data on the polymorphism of autosomic locus and the Y-chromosome by V. N. Kharkov, N. A. Kolesnikov, L. V. Valikhova, A. A. Zarubin, M. G. Svarovskaya, A. V. Marusin, I. Yu. Khitrinskaya, V. A. Stepanov

“…Variants of different haplogroups of the Y-chromosome in the Khanty, Khakas and Tuvans go back to their common ancestral lines. …”
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Klaus Berger, Wolfgang Beinert, Christoph Wetzel, Bilder des Himmels: die geschichte des Jenseits von der Bibel bis zur gegenwart by Christoph Stenschke

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MicroRNA-122 protects against interferon-α-induced hepatic inflammatory response via the Janus kinase–signal transducer and activator of transcription pathway by Fanwei Liu, Bowen Liu, Shanshan Xu, Yinhua Ni, Xiaoli Liu

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4,6-Disubstituted pyrimidine-based microtubule affinity-regulating kinase 4 (MARK4) inhibitors: synthesis, characterization, in-vitro activity and in-silico studies by Ashanul Haque, Khalaf M. Alenezi, Mohd. Saeed Maulana Abdul Rasheed, Md. Ataur Rahman, Saleha Anwar, Shahzaib Ahamad, Dinesh Gupta

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Genome-wide identification of the wall-associated kinase gene family and their expression patterns under various abiotic stresses in soybean (Glycine max (L.)... by Xiangnan Li, Sifei Qi, Lingzhi Meng, Peisen Su, Yongwang Sun, Nan Li, Dan Wang, Yinglun Fan, Yong Song

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Nouveaux fossiles néandertaliens et réinterprétation stratigraphique des collections classiques de La-Chaise-de-Vouthon (vallée de La Tardoire, Charente) by Diego López-Onaindia, Kim Genuite, Edgar Téllez, Mónica Villalba de Alvarado, Elle Liagre, Laure Thimon, Juliette Hantrais, Ana Pantoja-Pérez, Nohemi Sala, Asier Gómez-Olivencia, Christine Couture-Veschambre

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Hubungan Explosive Power Otot Lengan dan Koordinasi Mata-Tangan Terhadap Kemampuan Servis Atas Atlet Bolavoli Kuansing Kabupaten Kuantan Singingi by Dupri

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Protective Effects of Intravitreal Injection of the Rho-Kinase Inhibitor Y-27632 in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rAION) by Zuohuizi Yi, Liao Chen, Xiaoling Wang, Changzheng Chen, Yiqiao Xing

“…We sought to explore the effects of intravitreal injection of the Rho-kinase inhibitor Y-27632 in a rodent model of nonarteritic anterior ischemic optic neuropathy (rAION). …”
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The activation of Chlamydomonas reinhardtii alpha amylase 2 by glutamine requires its N‐terminal aspartate kinase–chorismate mutase–tyrA (ACT) domain by Lisa Scholtysek, Ansgar Poetsch, Eckhard Hofmann, Anja Hemschemeier

“…This activating effect required the enzyme's N‐terminal aspartate kinase–chorismate mutase–tyrA domain. Gln is the first N assimilation product and not only a central compound for the biosynthesis of N‐containing molecules but also a recognized signaling molecule for the N status. …”
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The Lck Paradox: Because of Inconsistent Experimental Evidence, the Role of the Protein Tyrosine Kinase p56lck in Early Thymic Development Remains Poorly Defined by Klaus Eichmann

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Adjuvant endocrine therapy with cyclin-dependent kinase 4/6 inhibitor, ribociclib, for localized hormone receptor-positive/HER2– breast cancer (LEADER) by Laura M. Spring, Lauren Scarpetti, Arielle J. Medford, Andrzej Niemierko, Amy Comander, Therese Mulvey, Lowell Schnipper, Steven J. Isakoff, Beverly Moy, Seth A. Wander, Jennifer Shin, Zanta Ephrem, Anneke R. Laposta, Elyssa Denault, Elizabeth Abraham, Gayle Calistro, Ekaterina Kalashnikova, Angel Rodriguez, Minetta C. Liu, Alexey Aleshin, Jeffrey Peppercorn, Leif W. Ellisen, Aditya Bardia

“…Abstract Optimal timing and dosing of adjuvant cyclin-dependent kinase (CDK) 4/6 inhibitor in early breast cancer is controversial. …”
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Induction of MAP Kinase Homologues during Growth and Morphogenetic Development of Karnal Bunt (Tilletia indica) under the Influence of Host Factor(s) from Wheat Spikes by Atul K. Gupta, J. M. Seneviratne, G. K. Joshi, Anil Kumar

“…Signaling pathways that activate different mitogen-activated protein kinases (MAPKs) in response to certain environmental conditions, play important role in mating type switching (Fus3) and pathogenicity (Pmk1) in many fungi. …”
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Upregulation of Cardiac IL-10 and Downregulation of IFN-γ in Balb/c IL-4−/− in Acute Chagasic Myocarditis due to Colombian Strain of Trypanosoma cruzi by Marcos Vinicius da Silva, Vera Lúcia de Almeida, Wendyson Duarte de Oliveira, Natália Carasek Matos Cascudo, Pollyana Guimarães de Oliveira, Crislaine Aparecida da Silva, Aline Cristina Souza da Silva, Maria Luíza Gonçalves dos Reis Monteiro, Rosana Rosa Miranda Correa, Milton Adriano Pelli Oliveira, Ruy de Sousa Lino-Júnior, Mara Rúbia Nunes Celes, Juliana Reis Machado

“…However, immune system regulation has not been fully elucidated. Thus, this study is aimed at evaluating IL-4 influence on acute phase of Trypanosoma cruzi experimental infection through dosage of cytokine levels in cardiac homogenate of infected Balb/c WT and Balb/c IL-4−/− as well as its histopathological repercussions. …”
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Deletion of cyclin dependent kinase inhibitor 2a gene as a marker of oropharyngeal carcinomas non-associated with human papillomavirus and its prognostic value by I.S. Shponka, Bondarenko O.O. Bondarenko ч, O.V. Kovtunenko, V.V. Rakhmanov

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Adiponectin Inhibits LPS-Induced HMGB1 Release through an AMP Kinase and Heme Oxygenase-1-Dependent Pathway in RAW 264 Macrophage Cells by Mohamed Elfeky, Ryuji Kaede, Yuko Okamatsu-Ogura, Kazuhiro Kimura

“…Adiponectin, an adipokine, has potent anti-inflammatory properties. However, possible effects of adiponectin on lipopolysaccharide- (LPS-) induced HMGB1 release are unknown. …”
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Translations of Yarliqs of the Crimean khans to the Je­wish Community of Kyrk-Yer (Chufut-Kale) in the Archives of the Russian Federation (According to the Materials of the State Archive of the Republic of Crimea and the Russian State Historical Archive) by Prokhorov D.A.

Subjects: “…crimean khanate…”
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Nitric Oxide Activates Apoptosis Signal - Regulating Kinase 1 (ASK 1) Forming S-Nitrosothiols with Reactive Thioredoxin SH-Groups.... by Vadim V. Sumbayev, Inna M. Yasinska

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A semi-synchronous federated learning framework with chaos-based encryption for enhanced security in medical image sharing by Animesh Roy, Deva Raj Mahanta, Lipi B. Mahanta

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