Evaluation of Interleukin-23 and Creatine Kinase –MB (CK-MB) Levels in Acute Coronary Syndrome Patients with COVID-19 in Baghdad City by Zahraa kareem Yaseen, Farhan Abood Risan, Suhad Hassan Aubaid

Subjects: Get full text

Genome analysis uncovers an inverse correlation between alterations in P21‐activated kinases and patient survival across multiple cancer types by Jessie M. Vo, Linh M. La, Ananda V. Anderson, Abdulaziz H. Alanazi, Payaningal R. Somanath

Subjects: Get full text

Fatty Acid Composition and Anticancer Activity of Neutral and Polar Lipids of Pacific Oyster ( Crassostrea gigas ) Cultured in Khanh Hoa Coast in Vietnam by Minh Van Nguyen, Derrick Kakooza, Thi Hong Tuoi Do, Anh Phuong Thi Tran, Han The Nguyen, Ngoc Quang Tran

“…In this study, we investigated the fatty acid composition and anticancer activity of neutral and polar lipid fractions extracted from Crassostrea gigas oysters cultured in Nha Phu Lagoon, Khanh Hoa Coast, harvested during the five months of January, April, May, September, and November. …”
Get full text

Christian Fuchs and Klaus Unterberger (eds.): The public service media and public service internet manifesto, University of Westminster Press, London, 2021 by Kljajić Sanja

Get full text

Focal Adhesion Kinase and ROCK Signaling Are Switch-Like Regulators of Human Adipose Stem Cell Differentiation towards Osteogenic and Adipogenic Lineages by Laura Hyväri, Miina Ojansivu, Miia Juntunen, Kimmo Kartasalo, Susanna Miettinen, Sari Vanhatupa

“…This study examined the significance of focal adhesion kinase (FAK), Rho-Rho-associated protein kinase (Rho-ROCK), and their downstream target extracellular signal-regulated kinase 1/2 (ERK1/2) on hASCs differentiation towards osteoblasts and adipocytes. …”
Get full text

Wharton’s Jelly-Derived Mesenchymal Stem Cells with High Aurora Kinase A Expression Show Improved Proliferation, Migration, and Therapeutic Potential by Sun Jeong Kim, Sang Eon Park, Jang Bin Jeong, Shin Ji Oh, Alee Choi, Yun Hee Kim, Suk-joo Choi, Soo-young Oh, Gyu Ha Ryu, Hong Bae Jeon, Jong Wook Chang

“…This study is aimed at identifying the upregulated genes in human Wharton’s jelly-derived MSCs (WJ-MSCs) with high proliferation potential using mRNA sequencing. Aurora kinase A (AURKA) and dedicator of cytokinesis 2 (DOCK2) were selected as the upregulated genes, and their effects on proliferation, migration, and colony formation of the WJ-MSCs were verified using small interfering RNA (siRNA) techniques. mRNA expression levels of both the genes were positively correlated with the proliferation capacity of WJ-MSCs. …”
Get full text

Sequential Kinase Inhibition (Idelalisib/Ibrutinib) Induces Clinical Remission in B-Cell Prolymphocytic Leukemia Harboring a 17p Deletion by H. Coelho, M. Badior, T. Melo

“…A reduced-intensity conditioning allo-HSCT from a HLA-matched unrelated donor was performed, and, thereafter, the patient has been in complete remission for 10 months now. …”
Get full text

Inhibitory effects of limonin on the proliferation of non-small cell lung cancer cells via targeting S-phase kinase-associated protein 2 by Zhu Jiaxian, Zhang Mengting, Li Shengqing, Liu Yongqiang

Subjects: Get full text

Placental Growth Factor, Soluble fms-Like Tyrosine Kinase 1, Soluble Endoglin, IL-6, and IL-16 as Biomarkers in Preeclampsia by Carmen Rădulescu, Anca Bacârea, Adina Huțanu, Rozalia Gabor, Minodora Dobreanu

Get full text

Evaluation of Real-World Evidence to Assess Effectiveness Outcomes of Janus Kinase Inhibitors for Rheumatoid Arthritis: A Systematic Review of US Studies by Gandy C, Bazzazzadehgan S, Bruera S, Huang Y

Subjects: Get full text

Les jardins littéraires de Michel Goulet ou Comment un artiste fait asseoir des textes sur des chaises by Marc André Brouillette

Get full text

3D-QSAR Study on a Series of VEGFR-2 Kinase Inhibitors: 3-Pyrrole Substituted Indolin-2-Ones Compounds by Shunlai Li, Rutao Zhang, Hongguang Du

“…The vascular endothelial growth factor receptor-2 kinases (VEGFR-2) are attractive targets for the development of anticancer agents. …”
Get full text

Cost-effectiveness Analysis of Lorlatinib in Patients Previously Treated with Anaplastic Lymphoma Kinase Inhibitors for Non-small Cell Lung Cancer in Greece by George Gourzoulidis, Oresteia Zisimopoulou, Nadia Boubouchairopoulou, Christina Michailidi, Chrissy Lowry, Charalampos Tzanetakos, Georgia Kourlaba

“…**Conclusion:** The present analysis suggests that lorlatinib may be considered as a cost-effective option compared with P-ChT in Greece for the treatment of patients with advanced, ALK-positive NSCLC whose disease has progressed after at least one second-generation ALK tyrosine kinase inhibitor. …”
Get full text

Christopher Conway, Marek Paryż and David Rio, editors. The Western in the Global Literary Imagination. by Alessandra Magrin Haas

Get full text

Icaritin alleviates motor impairment and osteoporosis in Parkinson’s disease mice via the ER-PI3K/Akt pathway by Xianmei Lin, Xinyu Zhou, Xingman Liu, Lingqiong Xia, Jing Cai, Nanqu Huang, Yong Luo, Weidong Wu

Subjects: Get full text

Wnętrze salonu – wnętrze piekieł? „Anioł zagłady” Luisa Buñuela (1962) by Krzysztof Lipka

Subjects: Get full text

Reinterpretation of the Words Falyanzur and Tha'am in Qs 'Abasa Verse 24 to Build Public Nutrition Awareness by Annisa Nur Hanifah, Belqes Al Sowaidi, Andri Nirwana AN

Subjects: Get full text

Palbociclib-induced Toxic Epidermal Necrolysis: A Case Report with Review of All Cases Secondary to Cyclin-dependent Kinase 4/6 Inhibitors by Aurore Devoldere, Clélia Vanhaecke, Pauline Soibinet, Brahim Azzouz, Manuelle Viguier

Get full text

DYRK1A (Dual-Specificity Tyrosine-Phosphorylated and -Regulated Kinase 1A): A Gene with Dosage Effect During Development and Neurogenesis by M. Dierssen, M. Martínez de Lagrán

“…DYRKs (dual-specificity tyrosine-regulated kinases) are an emerging family of evolutionarily conserved dual-specificity kinases that play key roles in cell proliferation, survival, and development. …”
Get full text

Evaluating the Effectiveness of Cyclin-Dependent Kinase 4/6 Inhibitors in Early- and Very Early-Onset Metastatic Breast Cancer: A Multicenter Study by Akif Doğan, Nurullah İlhan, Goncagül Akdağ, Sedat Yıldırım, Mustafa Seyyar, Zeynep Yüksel Yaşar, Hande Nur Erölmez, Heves Sürmeli, Buğra Öztosun, Özlem Nuray Sever, Hatice Odabaş, Mahmut Emre Yıldırım, Devrim Çabuk, Nedim Turan, Mahmut Gümüş

“…<i>Materials and Methods</i>: This multicenter, retrospective study evaluated the efficacy and safety of cyclin-dependent kinase 4 and 6 (CDK 4/6) inhibitors, ribociclib, and palbociclib, in combination with endocrine therapy in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative metastatic breast cancer. …”
Get full text