Showing 581 - 600 results of 2,809 for search 'Khaas~', query time: 2.52s Refine Results
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    Sentiment analysis of the Hamas-Israel war on YouTube comments using deep learning by Ashagrew Liyih, Shegaw Anagaw, Minichel Yibeyin, Yitayal Tehone

    Published 2024-06-01
    “…Moreover, we have used the SMOTE data balancing technique and used different data splits, but the 80/20 train-test split ratio has the highest accuracy. For classification model building, commonly used classification algorithms LSTM, Bi-LSTM, GRU, and Hybrid of CNN and Bi-LSTM were applied, and their performance is compared. …”
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    Inflammatory adhesion mediates myocardial segmental necroptosis induced by mixed lineage kinase domain-like protein in acute myocardial infarction by Lijiang Wei, Naifu Wan, Wentong Zhu, Chenchen Liu, Zeyu Chen, Wuwei Rong, Lujun Zhang, Meifeng Xie, Yueqi Qin, Ting Sun, Qing Jing, Ankang Lyu

    Published 2025-01-01
    “…Although existing reports indicating that mixed lineage kinase domain-like protein (MLKL) is involved in macrophage necroptosis and inflammasome activation, the downstream mechanism of MLKL in necroptosis remain poorly characterized in AMI. …”
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  8. 588

    Determinants Present in the Receptor Carboxy Tail Are Responsible for Differences in Subtype-Specific Coupling of β-Adrenergic Receptors to Phosphoinositide 3-Kinase by Julie Simard, Matthieu Boucher, Rachel Massé, Terence E. Hébert, Guy Rousseau

    Published 2009-01-01
    “…An agonist-occupied β2-adrenergic receptor (β2-AR) recruits G protein receptor kinase-2 (GRK2) which is recruited to the membrane. …”
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  9. 589

    Detection of the Extended γ-Ray Emission around TeV Source 1LHAASO J0249+6022 with Fermi-LAT by Yunlu Gong, Liancheng Zhou, Qi Xia, Shan Chang, Jun Fang, Li Zhang

    Published 2025-01-01
    “…1LHAASO J0249+6022 is an extended very-high-energy γ -ray source discovered by the Large High-Altitude Air Shower Observatory. …”
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    Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers by Daehwan Kim, Heekyung Chung, Wen Liu, Kangjin Jeong, Tugba Y. Ozmen, Furkan Ozmen, Matthew J. Rames, Sangyub Kim, Xiao Guo, Nathan Jameson, Petrus R. de Jong, Steven Yea, Laurie Harford, Jiali Li, Cara A. Mathews, Deborah B. Doroshow, Vincent J. Charles, Doris Kim, Kimberlee Fischer, Ahmed A. Samatar, Adrian Jubb, Kevin D. Bunker, Kimberly Blackwell, Fiona Simpkins, Funda Meric-Bernstam, Gordon B. Mills, Olivier Harismendy, Jianhui Ma, Mark R. Lackner

    Published 2025-01-01
    “…Abstract Upregulation of Cyclin E1 and subsequent activation of CDK2 accelerates cell cycle progression from G1 to S phase and is a common oncogenic driver in gynecological malignancies. WEE1 kinase counteracts the effects of Cyclin E1/CDK2 activation by regulating multiple cell cycle checkpoints. …”
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    Constitutive activation of the Src-family kinases Fgr and Hck enhances the tumor burden of acute myeloid leukemia cells in immunocompromised mice by Sherry T. Shu, Li Chen, Giancarlo Gonzalez-Areizaga, Thomas E. Smithgall

    Published 2025-01-01
    “…Abstract Overexpression of the myeloid Src-family kinases Fgr and Hck has been linked to the development of acute myeloid leukemia (AML). …”
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    Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis by Yajun Deng, Liang Yang, Qiqi Xie, Fengbiao Yang, Guoqiang Li, Guangzhi Zhang, Shaoping Li, Zuolong Wu, Jing Wang, Xuewen Kang

    Published 2020-01-01
    “…This study is aimed at investigating protein kinase A (PKA) expression in neuropathic pain and its possible mechanisms of involvement. …”
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    Imaging Expression of Cytosine Deaminase-Herpes Virus Thymidine Kinase Fusion Gene (CD/TK) Expression with [I]FIAU and PET by Trevor Hackman, Michail Doubrovin, Julius Balatoni, Tatiana Beresten, Vladimir Ponomarev, Bradly Beattie, Ronald Finn, William Bornmann, Ronald Blasberg, Juri Gelovani Tjuvajev

    Published 2002-01-01
    “…Double prodrug activation gene therapy using the Escherichia coli cytosine deaminase (CD)herpes simplex virus type 1 thymidine kinase ( HSV1-tk ) fusion gene ( CD/TK ) with 5-fluorocytosine (5FC), ganciclovir (GCV), and radiotherapy is currently under evaluation for treatment of different tumors. …”
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    Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion. by Dominique Dorin-Semblat, Jean-Philippe Semblat, Romain Hamelin, Anand Srivastava, Marilou Tetard, Graziella Matesic, Christian Doerig, Benoit Gamain

    Published 2025-01-01
    “…Here, we aimed to identify the kinases mediating this phosphorylation. We report that Human and Plasmodium falciparum Casein Kinase 2α are involved in the phosphorylation of the extracellular region of VAR2CSA. …”
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    Coronary Artery and Peripheral Vascular Disease in a Patient with Poorly Differentiated Thyroid Cancer Treated with the Tyrosine Kinase Inhibitor Lenvatinib by Vineeth Sukrithan, Lisa Kim, Jennifer A. Sipos, Ashima Goyal, Ye Zhou, Daniel Addison, Manisha Shah, Bhavana Konda, Ajay Vallakati

    Published 2023-01-01
    “…A subset of patients with differentiated thyroid carcinoma develop radioiodine refractory (RAIR) incurable disease, which typically has a poor prognosis. The multitargeted tyrosine kinase inhibitor lenvatinib has demonstrated significant improvements in progression-free survival in RAIR thyroid cancers compared to placebos. …”
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