Cost-effectiveness of tyrosine kinase inhibitor treatment strategies for chronic myeloid leukemia in South Africa by Rochelle Woudberg, Edina Sinanovic

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Overall survival of patients with KIT-mutant metastatic GIST in the era of multiple kinase inhibitor availability by Valerie Haller, Carina Reiff, Rainer Hamacher, Karina Kostbade, Moritz Kaths, Juergen Treckmann, Stefanie Bertram, Yasmin Zaun, Sebastian Bauer, Johanna Falkenhorst

“…Abstract Purpose The prognosis of patients with metastatic GIST and imatinib-sensitive primary mutations has significantly improved. However, limited data are available to inform patients about outcomes across different lines of treatment. …”
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Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation by Giuseppe Vassalli, Giuseppina Milano, Tiziano Moccetti

“…The four best-characterized MAPK subfamilies are the c-Jun NH2-terminal kinase (JNK), extracellular signal- regulated kinase-1/2 (ERK1/2), p38 MAPK, and big MAPK-1 (BMK1/ERK5). …”
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MAP4 kinase-regulated reduced CLSTN1 expression in medulloblastoma is associated with increased invasiveness by Ece Sönmez, Shen Yan, Meng-Syuan Lin, Martin Baumgartner

“…We previously identified CLSTN1 as a putative target of the pro-invasive kinase MAP4K4, which we found to reduce CLSTN1 surface expression. …”
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The Multi‐Kinase Inhibitor GZD824 (Olverembatinib) Shows Pre‐Clinical Efficacy in Endometrial Cancer by Dongli Liu, Dylan Glubb, Tracy O'Mara, Caroline E. Ford

“…GZD824, also known as olverembatinib, is a multi‐kinase inhibitor previously investigated in clinical trials for chronic myeloid leukaemia and Ph+ acute lymphoblastic leukaemia as a BCR‐ABL inhibitor. …”
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Gambaran Kadar Troponin T dan Creatinin Kinase Myocardial Band pada Infark Miokard Akut by Rendi Dwi Prasetyo, Masrul Syafri, Efrida .

“…Diagnosis IMA dapat dilakukan dengan cara: anamnesis, abnormalitas Elektrokardiogram (EKG), peningkatan Creatinin Kinase Myocardial Band (CKMB), dan cardiac specific troponin (cTn)T. …”
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Spatial Downscaling and Simulation of TRMM Data at High Altitudes — A Case Study of Lhasa River by DAWA Ciren, ZHAO Keke, GU Yu, LUO Xiaoyu, CIWANG Dunzhu

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Metabolic Basis for Thyroid Hormone Liver Preconditioning: Upregulation of AMP-Activated Protein Kinase Signaling by Luis A. Videla, Virginia Fernández, Pamela Cornejo, Romina Vargas

“…In this context, adenosine-monophosphate- (AMP-) activated protein kinase (AMPK) constitutes an intrahepatic energy sensor regulating physiological energy dynamics by limiting anabolism and stimulating catabolism, thus increasing ATP availability. …”
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Cerebrovascular stenosis related to tyrosine kinase inhibitor for chronic myeloid leukemia: two illustrative cases by Nozomi Sasaki, Yukiko Enomoto, Takamitsu Hori, Hirofumi Matsubara, Yusuke Egashira, Tsuyoshi Izumo

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Nuevos datos sobre Aj Ch’aaj Naah, Aj K’uhuun de Toniná by Ángel A. Sánchez Gamboa, Alejandro Sheseña, Guido Krempel

“…The figure of Aj Ch’aaj Naah is undoubtedly one of the most outstanding in the history of the Aj K’uhuun officials of Tonina. …”
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Two Cysteines in Raf Kinase Inhibitor Protein Make Differential Contributions to Structural Dynamics In Vitro by Hyun Sang Cho, Mohammad Faysal Al Mazid, Eun-Young Lee, Md Abu Rayhan, Hyoun Sook Kim, Byung Il Lee, Hye Jin You

Subjects: “…Raf kinase inhibitor protein…”
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ERK1/2 mitogen‐activated protein kinase dimerization is essential for the regulation of cell motility by Dalia de laFuente‐Vivas, Vincenzo Cappitelli, Rocío García‐Gómez, Sara Valero‐Díaz, Camilla Amato, Javier Rodriguéz, Santiago Duro‐Sánchez, Alexander vonKriegsheim, Michael Grusch, José Lozano, Joaquín Arribas, Berta Casar, Piero Crespo

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Glena bipennaria bipennaria and Apatelodes pandara (Lepidoptera): new defoliating insects associated with Khaya in Brazil by Luana de Souza Covre, Robert A. Haack, Carlos Alberto Hector Flechtmann

“… The expansion of African mahogany (Khaya spp.) plantations in Brazil has led to an increase in the number of associated insect pests. …”
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Sickling Cells, Cyclic Nucleotides, and Protein Kinases: The Pathophysiology of Urogenital Disorders in Sickle Cell Anemia by Mário Angelo Claudino, Kleber Yotsumoto Fertrin

“…The authors review what is known about the deleterious effects of sickling on the genitourinary tract and how the role of cyclic nucleotides signaling and protein kinases may help understand the pathophysiology underlying these manifestations and develop novel therapies in the setting of urogenital disorders in sickle cell disease.…”
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Les collections composites du musée de la Chasse et de la Nature by Marie-Christine Prestat

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Oral Trypanosoma cruzi Transmission Resulting in Advanced Chagasic Cardiomyopathy in an 11-Month-Old Male by Melissa S. Nolan, Joseane Elza Tonussi Mendes, Andres Ricardo Perez Riera, Gabriel Zorello Laporta

“…This practice could place infants at an increased risk of oral Trypanosoma cruzi infection and severe Chagasic cardiac disease.…”
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Evaluation of Three Adolescent Sexual Health Programs in Ha Noi and Khanh Hoa Province, Vietnam by Van Pham, Hoang Nguyen, Le Huu Tho, Truong Tan Minh, Porntip Lerdboon, Rosemary Riel, Mackenzie S. Green, Linda M. Kaljee

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Kontestasi Kuasa Kepemimpinan Formal dengan Informal dalam Kebijakan Publik dan Politik Keseharian by Yeby Ma'asan Mayrudin, Nabilla Amalia Husna, Fanny Rosye Yuliati

“…Persoalan tersebut menunjukkan adanya persilangan kontestasi kuasa antara aktor. Interseksi ini memunculkan pertarungan kuasa dominatif di antara kedua aktor tersebut. …”
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Pengaruh Likopen terhadap Kadar Soluble FMS-Like Tyrosine Kinase 1 pada Preeklamsi by Vaulinne Basyir, Prima Nanda Fauziah, Akhmad Yogi Pramatirta, Yanwirasti Yanwirasti, Johanes C. Mose, Fadil Oenzil

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Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles by Chunying Li, Wenwen Wang, Junyi Shao, Sen Zhou, Xiaolin Ji, Youxia Xi, Qiuyang Xu, Yuhan Huang, Jingle Wang, Yilin Wan, Zhiming Li

“…Additionally, the accumulated CD8+ T cells release interferon-γ (IFN-γ) to activate janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway in keratinocytes. …”
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