The Potentials of Integration in the Historical Khan of Al-Exandria-Babylon by Shaker Fatima Sadiq, Musa Rashaa Malik

Subjects: Get full text

Malomunski kodicil iz 18. stoljeća - crtica iz prošlosti svakodnevice Opatijskoga krasa by Robert Doričić, Marko Medved

“…Osim što daje uvid u prošlost nasljednopravnih odnosa, ona predstavlja višestruko vrijedan izvor za istraživanje novovjekovne prošlosti na području Opatijskoga krasa kojemu selo Male Mune pripada, osobito uzimajući u obzir rijetkost takvoga arhivskoga gradiva. …”
Get full text

Kriminalitet og klasse: Selvrapportert kriminalitet og annen problemetferd blant norsk ungdom by Ketil Skogen, Lars Wichstrøm

Get full text

Biophysical and biochemical evidence for the role of acetate kinases (AckAs) in an acetogenic pathway in pathogenic spirochetes. by Ranjit K Deka, Shih-Chia Tso, Wei Z Liu, Chad A Brautigam

“…We established that the enzyme exists as a dimer in solution, and then determined its crystal structure at a resolution of 1.36 Å, showing that the protein has a similar fold to other known acetate kinases. …”
Get full text

Tomato mitogen-activated protein kinase: mechanisms of adaptation in response to biotic and abiotic stresses by Yumei Shi, Zhifang Zhang, Zhenghao Yan, Honglong Chu, Changxin Luo

Subjects: “…mitogen-activated protein kinases…”
Get full text

The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium by Coral Pardo-Esté, Coral Pardo-Esté, Francisca Urbina, Nicolas Aviles, Nicolas Pacheco, Alan Briones, Carolina Cabezas, Vicente Rojas, Valentina Pavez, Yoelvis Sulbaran-Bracho, Yoelvis Sulbaran-Bracho, Alejandro A. Hidalgo, Juan Castro-Severyn, Juan Castro-Severyn, Claudia P. Saavedra

Subjects: Get full text

Did selective kinase inhibitors change the management of patients with radioiodine-refractory thyroid cancer? by Tommaso Porcelli, Cristina Luongo, Anna Cerbone, Carmine Di Luccio, Mariantonia Nacchio, Maria Angela De Stefano, Martin Schlumberger, Domenico Salvatore

Subjects: Get full text

Kho Gaye Hum Kahan – A valuable narration on losing ourselves in this digital world by Tanu Singla, Nikhil Gautam

Get full text

VÂKIDÎ’NIN FUTÛHU’Ş-ŞAM ISIMLI ESERINDE GEÇEN HAMÂSE ŞIIRLERININ ANALIZI by Bekir Yıldırım

Get full text

Altered Forebrain Functional Connectivity and Neurotransmission in a Kinase-Inactive Mouse Model of Autism by Shiyu Tang PhD, Elizabeth M. Powell PhD, Wenjun Zhu MS, Fu-Sun Lo MD, Reha S. Erzurumlu PhD, Su Xu PhD

“…MET , the gene encoding the tyrosine kinase receptor for hepatocyte growth factor, is a susceptibility gene for autism spectrum disorder (ASD). …”
Get full text

Machine Learning-Assisted Drug Repurposing Framework for Discovery of Aurora Kinase B Inhibitors by George Nicolae Daniel Ion, George Mihai Nitulescu, Dragos Paul Mihai

Subjects: Get full text

Unveiling the Anti-Angiogenic Potential of Small-Molecule (Kinase) Inhibitors for Application in Rheumatoid Arthritis by Fatemeh Khodadust, Eva M. L. Philippon, Maarten M. Steinz, Jan Piet van Hamburg, Johan van Meerloo, Judy R. van Beijnum, Gerrit Jansen, Sander W. Tas, Conny J. van der Laken

“…This study evaluated potential anti-angiogenic effects of several compounds including small-molecule kinase inhibitors, such as sunitinib (pan-kinase inhibitor), tofacitinib (JAK-inhibitor), NIKi (NF-κB-inducing kinase inhibitor), and the integrin-targeting peptide fluciclatide, using a scratch assay and 3D spheroid-based models of angiogenesis. …”
Get full text

Tirosin Kinase Inhibitors in Chronic Graft versus Host Disease: From Bench to Bedside by Jacopo Olivieri, Sabrina Coluzzi, Imma Attolico, Attilio Olivieri

“…In many inflammatory fibrotic diseases, such as Systemic Scleroderma (SSc) and cGVHD with fibrotic features, an abnormal activation of transforming growth factor (TGFβ) and platelet-derived growth factor receptor (PDGF-R) pathways have been observed. Tyrosin Kinase Inhibitors (TKIs), which are currently used for treatment of patients with Chronic Myeloid Leukemia (CML), share potent antifibrotic and antiinflammatory properties, being powerful dual inhibitors of both PDGF-R and TGFβ pathways. …”
Get full text

Stiff Substrates Enhance Endothelial Oxidative Stress in Response to Protein Kinase C Activation by Rebecca Lownes Urbano, Swathi Swaminathan, Alisa Morss Clyne

“…The objective of this study was to determine if substrate stiffness increased endothelial monolayer reactive oxygen species (ROS) in response to protein kinase C (PKC) activation and if this oxidative stress then impacted adherens junction integrity. …”
Get full text

The Role of Beta-hCG Progesterone and Creatine Kinase in the Early Diagnosis of Ectopic Pregnancies by Nagihan Sarı, Hatice Işık, Hatice Başar, Ali Seven, Ahmet Bostancı

Subjects: Get full text

Crosstalk between Substrates and Rho-Associated Kinase Inhibitors in Cryopreservation of Tissue-Engineered Constructs by Arindam Bit, Awanish Kumar, Abhishek Kumar Singh, Albert A. Rizvanov, Andrey P. Kiassov, Pradeep Kumar Patra, Munish Kumar, Akalabya Bissoyi

“…Several natural and synthetic materials are extensively used as substrates for tissue engineering constructs and cryopreservation because they promote cell attachment and proliferation. Rho-associated kinase (ROCK) inhibitors can improve the physiological function and postthaw viability of cryopreserved MSCs. …”
Get full text

Clinical relevance and druggability of sole reciprocal kinase fusions: A large‐scale study by Jiao Feng, Tonghui Ma, Chunyang Wang, Baoming Wang, Qian Liu, Zhengchuang Liu, Houquan Tao, Zaiyuan Ye

“…Abstract Background Building on our prior work that RNA alternative splicing modulates the druggability of kinase fusions, this study probes the clinical significance of sole reciprocal fusions. …”
Get full text

Janus kinase inhibitor treatment for inflammatory diseases: excess or no excess risk of venous thromboembolism? by Yachar Dawudi, Samuel Benarroch, Hélène Helfer, David M. Smadja, Isabelle Mahé

Subjects: Get full text

High Expression of Polo-Like Kinase 1 Is Associated with Early Development of Hepatocellular Carcinoma by Wei Sun, Qi Su, Xiankui Cao, Bin Shang, Aishan Chen, Hongzhuan Yin, Baolin Liu

“…Polo-like kinase 1 (PLK1), one of serine/threonine-protein kinase, has been demonstrated to play pivotal roles in malignant transformation. …”
Get full text

FDA-approved kinase inhibitors: a promising therapeutic avenue for traumatic brain injury by Dezhu Gao, Yu Shi, Zhiliang Wang, Weiming Liu

Subjects: Get full text