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4581
Immunoregulatory programs in anti‐N‐methyl‐D‐aspartate receptor encephalitis identified by single‐cell multi‐omics analysis
Published 2025-01-01“…Additionally, activation of Toll‐like receptor 2 (TLR2) in myeloid cells was noted, which may connect to tumor necrosis factor‐alpha (TNF‐α) secretion. This cytokine may contribute to the activation of B and T cells, thereby perpetuating immune dysregulation. …”
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4582
Psychometric properties of the health literacy questionnaire tested in Vietnamese adults with chronic diseases
Published 2025-01-01“…Confirmatory factor analyses (CFA) testing nine one-factor models were fitted to test the structure of each scale, and a nine-factor model tested the hypothesized structure of the HLQ, followed by the calculation of scale reliability using Cronbach’s alpha. Results No item had floor effects, and only eight items showed ceiling effects. …”
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4583
The Collection of Rhizosphere Microorganisms: its importance for the study of associative plant-bacterium interactions
Published 2020-05-01“…This group includes nitrogen-fixing soil alpha-proteobacte-ria of the genus Azospirillum, which form the core of the IBPPM collection. …”
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4584
Validity and reliability of the brief form of the normative male alexithymia scale among Chinese patients after radical prostatectomy
Published 2025-01-01“…Additionally, Pearson’s correlation, t-tests, and analysis of variance (ANOVA) were used to identify factors influencing the NMAS-BF. The Cronbach’s alpha coefficient for the Chinese version of the NMAS-BF was 0.856. …”
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4585
Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavi...
Published 2022-01-01“…Betaine decreased the expression of the NLRP3 inflammasome, decreased the expression of M1 polarization markers, tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β), COX-2, and iNOS and promoted the expression of M2 polarization marker CD206. …”
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4586
Lipids as key biomarkers in unravelling the pathophysiology of obesity-related metabolic dysregulation
Published 2025-02-01“…A stepwise logistic regression revealed three metabolites associated with increased risk of obesity (14-methylheptadecanoic acid, 4′-apo-beta,psi-caroten-4'al and 6E,9E-octadecadienoic acid), and three with lower risk of obesity (19:0(11Me), 7,8-Dihydro-3b,6a-dihydroxy-alpha-ionol 9-[apiosyl-(1->6)-glucoside] and 4Z-Decenyl acetate). …”
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4587
Navigating the fear: assessing nursing students’ concerns and preventive practices in response to Monkeypox in Egypt
Published 2025-01-01“…Reliability was confirmed with Cronbach’s alpha values ranging from 0.87 to 0.94. Data analysis included descriptive statistics, Spearman correlation, and multiple linear regression using SPSS Version 23. …”
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4588
Effects of Aerobic Exercise on Rats with Hyperandrogenic Polycystic Ovarian Syndrome
Published 2021-01-01“…Compared with the NC group, the levels of testosterone (T), estradiol (E2), follicle-stimulating hormone (FSH), LP, anti-Müllerian hormone (AMH), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and free fatty acids (FFA) were all significantly augmented in the PC group (all p<0.05). …”
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4589
Karakter Güçlerinin Sınıflandırılması ve Ölçülmesi: VIA-IS-P ve GACS-24 Yetişkin Formlarının Türkçeye Uyarlanması
Published 2024-12-01“…VIA Karakter Güçleri Envanteri'nin 24 alt boyutuna ait Cronbach Alpha iç tutarlılık katsayısı, birinci örneklem için .63 ile .89 arasında (X̄ = .75), ikinci örneklem için ise .62 ile .85 arasında (X̄ = .73) değişmektedir. …”
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4590
Serum metabolic profiles in quails: Effects of age, breed, and sex
Published 2025-01-01“…At 20 days of age (D20), quails had high levels of serum thymidine and alpha-D-glucose, while at 70 days of age (D70), the lipids, including 3-isothujone, 15-deoxy-d-12,14-PGJ2, and 2-aminobut-2-enoate dominated the serum. …”
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4591
Structural Disruption of Cilia and Increased Cytoplasmic Tubulin in Biliary Atresia—An Exploratory Study Focusing on Early Postoperative Prognosis Following Portoenterostomy
Published 2025-01-01“…The detrimental effect of HIF-1alpha pathway activation over early native liver survival was confirmed, although independently from PC or cytoplasmic tubulin features.…”
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4592
A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant
Published 2024-01-01“…The data revealed that anti-inflammatory compounds from this plant suppress iNOS, myeloperoxidase, COX, LOX, and cytokines (like TNF-alpha, IL-1ß, LTB4, IL-12, and IL-6) to reduce inflammation. 5-O-Butyl-embelin, 2-hydroxy-5-ethoxy-3-nonyl1, 4-benzoquinone, 5-O-methylembelin, 5-O-methyl-rapanone, s-saponin, and 5-O-ethylembelin are some phytochemicals of A. corniculatum with anticancer properties, although their mechanism is unclear. …”
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4593
uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease
Published 2025-02-01“…Results Single-cell sequencing revealed a significant reduction in the expression of NFKBIA, encoding NF-κB inhibitor alpha (IkBa), which facilitates the nuclear translocation of p65, a key NF-κB component. uN2CpolyG directly interacted with and sequestered p65 in nuclear inclusions, leading to reduced phosphorylated p65 (p-p65) levels. …”
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4594
Evaluating strategies for global respiratory pandemic control at ports: a modelling study
Published 2025-01-01“…To assess different infection parameters, we explored three variants (Alpha, Delta and Omicron), four prevalences (0.1%, 0.5%, 1% and 2%) and three quarantine compliances (50%, 90% and 100%).Results Across the prevalences with no intervention, our modelled simulations estimate that approximately 3%, 15%, 28% and 47% of crews are infected, totalling around 9400, 44 900, 82 600 and 141 300 infections. …”
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4595
Development of a novel instrument to measure Japanese psychiatric nurses’ technological competency as caring in nursing
Published 2025-01-01“…Results: The developed instrument comprises 22 items with a 4-factor structure: competency to practice caring and person-centered care (Factor 1); competency to recognize and respond to ethical issues in psychiatry (Factor 2); competency to utilize technology in psychiatry (Factor 3); and competence to practice care for the preservation of human dignity and shared decision making (Factor 4). Cronbach’s alpha for the entire scale was 0.864, while that for factors 1-4 was 0.911, 0.814, 0.773, and 0.64, respectively. …”
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4596
Association between time consumption of electronic screens with eating behaviors and academic performance for pupils in elementary schools
Published 2025-01-01“…A pilot study was conducted to measure reliability from December 28 to 30, 2023. By Cronbach’s Alpha measurement, the results were 0. 815 at SPSS version 26. …”
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4597
Optimal dietary vitamin E level facilitates ovarian development of female largemouth bass (Micropterus salmoides) broodstock
Published 2025-04-01“…Dietary vitamin E supplementation significantly upregulated the expression of genes involving vitamin E transfer, ovarian development, and hormone, including alpha-tocopherol transfer protein, luteinizing hormone, follicle-stimulating hormone, vitellogenin receptor (vgr), vitellogenin (vg), 17-beta-hydroxysteroid dehydrogenase (17β-hsd), cyclin-dependent kinase 2 (cdk2), and cytochrome P450 family 17 (cyp-17), with the highest expression levels detected in the 209.31 mg/kg group (P < 0.05). …”
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4598
Prediction of Immune Infiltration Diagnostic Gene Biomarkers in Kawasaki Disease
Published 2022-01-01“…KD diagnostic biomarkers, including the alkaline phosphatase (ALPL), endoplasmic reticulum degradation-enhancing alpha-mannosidase-like protein 2 (EDEM2), and histone cluster 2 (HIST2H2BE), were discovered (AUC=1.000) and verified utilizing the GSE73461 dataset (AUC=1.000). …”
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4599
Col1A1 as a new decoder of clinical features and immune microenvironment in ovarian cancer
Published 2025-01-01“…BackgroundsCollagen type I alpha 1 chain (COL1A1) is a key protein encoding fibrillar collagen, playing a crucial role in the tumor microenvironment (TME) due to its complex functions and close association with tumor invasiveness. …”
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4600
Multiple intracerebral hematomas during SEEG recording and intradural hemorrhage after spinal tap: A case report prompting more research on collagen IV gene mutation and oral nicot...
Published 2025-02-01“…(Trp1566Cys) in COL4A2 (NM_001846.4) encoding a collagen type‐IV alpha‐2 chain inherited from his seemingly healthy mother. …”
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