Similar Clinical and Surgical Outcomes Achieved with Early Compared to Late Anti-TNF Induction in Mild-to-Moderate Ulcerative Colitis: A Retrospective Cohort Study by Christopher Ma, Candace L. Beilman, Vivian W. Huang, Darryl K. Fedorak, Karen Wong, Karen I. Kroeker, Levinus A. Dieleman, Brendan P. Halloran, Richard N. Fedorak

“…Biologic agents targeting tumor necrosis factor alpha are effective in the management of ulcerative colitis (UC), but their use is often postponed until after failure of other treatment modalities. …”
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Parameter Uncertainty Analysis for Streamflow Simulation Using SWAT Model in Nashe Watershed, Blue Nile River Basin, Ethiopia by Megersa Kebede Leta, Dessalegn Geleta Ebsa, Motuma Shiferaw Regasa

“…The results show that CN_2, GW_DELAY, ALPHA_BNK, CH_N2, and SOL_AWC were the most sensitive parameter for the monthly period and had a great impact on the streamflow simulation. …”
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Analysis of the Multilevel Impact of Social Network Quality on Personality Dimensions in Purchasing by Maryam Akhavan Kharazian, Sona Shafieirad

“…The reliability of the questionnaire was confirmed using Cronbach’s alpha and the CR index, while its validity was confirmed using content, convergent, and discriminant validity methods. …”
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Reliability, validity, and minimal clinically important differences for the Thai-version of the Aberdeen Varicose Vein Questionnaire (AVVQ-Thai) in patients with chronic venous dis... by Suchat Wongsuwanich, Chaowanun Pornwaragorn, Chumpon Wilasrusmee, Termpong Reanpang, Pinit Noorit, Boonying Siribumrungwong, Kittipan Rerkaserm, Andrew Malcolm Garratt, Thoetphum Benyakorn, Saritphat Orrapin, Kanoklada Srikuea

“…The AVVQ-Thai had good internal consistency with Cronbach’s alpha of 0.783 and moderate reliability with the intraclass correlation coefficient of 0.67 (95%CI: 0.50, 0.79). …”
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PPARGC1A regulates transcriptional control of mitochondrial biogenesis in early bovine embryos by Muhammad Idrees, Muhammad Idrees, Zaheer Haider, Chalani Dilshani Perera, Safeer Ullah, Seo-Hyeon Lee, Seung Eun Lee, Sung-Sik Kang, Sung Woo Kim, Il-Keun Kong, Il-Keun Kong, Il-Keun Kong

“…Early embryos express peroxisome proliferator-activated receptor gamma co-activator alpha (PPARGC1A/PGC-1a), a protein essential for mitochondrial biogenesis. …”
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Survival and Its Predictors Among Patients Receiving Transarterial Chemoembolization for Hepatocellular Carcinoma in Ethiopia: A 6-Year Follow-Up Study by Abigia Ashenafi, Soliyana Demelash, Efrata Melaku, Haymanot Abe, Meron Yitna, Fisseha Tekle, Jiksa Dabessa, Biniam Araya, Yared Nigussie, Wondmagegn Demsiss, Ashenafi Zelalem, Song Jung Kim, Nebiyu Dereje

“…Data were extracted from patients' medical records, and vital status was ascertained from the patients' charts or by phone call to the next of kin. We used Kaplan-Meier estimator to determine survival functions and log-rank test to compare the survival functions in different groups. …”
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Anti-arthritic potential of crude sulfated polysaccharide from marine macroalgae Sargassum ilicifolium (Turner) C. Agardh: Regulation of cytokine cascade by Ramamoorthi Lavanya, Jeyabalan Srikanth, Sankar Seethalakshmi, Begum M. Yasmin, Duraipandian Chamundeeswari, Sekar Mahendran, Wong Ling Shing, Subramaniyan Vetriselvan

“…CSP was from the marine brown algae Sargassum ilicifolium from the Gulf of Mannar. …”
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Combination of Mangosteen (Garcinia mangostana L.) Pericarp Extract and Physical Exercise Decreases Atherosclerotic Lesions in Atherogenic Diet-Fed Rats by Andreas Arie Setiawan, . Sugiri, Awal Prasetyo, Eirin Yovita Kurniawan, Dominikus Evano Putra

“…The mangosteen pericarp (MP) has xanthone compounds, particularly alpha-mangostin (α-MG), which have been shown to exhibit potent antioxidant and anti-inflammatory activities. …”
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Contact-dependent growth inhibition (CDI) systems deploy a large family of polymorphic ionophoric toxins for inter-bacterial competition. by Tiffany M Halvorsen, Kaitlin A Schroeder, Allison M Jones, Disa Hammarlöf, David A Low, Sanna Koskiniemi, Christopher S Hayes

“…These CdiA-CT toxins are composed of two distinct domains based on AlphaFold2 modeling. The C-terminal ionophore domains are all predicted to form five-helix bundles capable of spanning the cell membrane. …”
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Measuring effective indicators for waste disposal in order to assess the sustainable environment: application of fuzzy approach by Mohammad Hossein Kabgani

“…., economic, technical, environmental, and social, based on their respective propensity.In the second step, a statistical analysis questionnaire was distributed among the study population, and Cronbach's alpha was explained for all four main factors of the study. …”
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Development and validation of the health education demand scale for HPV infected patients based on KANO model. by Yuying Zhang, Li Luo, Shuaihui Du, Die Hou, Yaling Zhang, Limin He, Lihua Zhou

“…In stage 2, Exploratory factor analysis formed a scale of 28 items in 5 factors: disease information demand, social support, emotional demand, family support and health education style demand. Cronbach's alpha was 0.940 for the entire scale and 0.763~0.908 for the five subscales in the positive items, 0.955 for the entire scale and 0.739~0.946 for the five subscales in reverse items. …”
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Validación psicométrica de la Escala de Premisas Histórico SocioCulturales de la Monogamia (EPHSCM) by Giovanna Escobar-Mota, Rozzana Sánchez-Aragón

“…Siguiendo el orden establecido en el procedimiento propuesto por Reyes Lagunes & García y Barragán (2008), el presente estudio describe el diseño y la validación de una escala confiable para la medición de las premisas histórico socioculturales de la monogamia en una muestra de 346 personas adultas mexicanas, conformada por 44 reactivos tipo Likert, mostrando cuatro factores con un alpha de Cronbach entre α = .74 y .93 que explican el 50.7% de la varianza, KMO = .94, prueba de esfericidad de Bartlett X2(44) = 9025.781, gl = 1128, p = .000.  …”
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The Inhibitory Effect of Connective Tissue Growth Factor Antibody on Postoperative Fibrosis in a Rabbit Model of Trabeculectomy by Kiana Hassanpour, Mozhgan Rezaei Kanavi, Narsis Daftarian, Azadeh Samaeili, Fatemeh Suri, Mohammad Pakravan, Azadeh Doozandeh, Sasha Afsar Aski, Maryam Fakhri, Afrooz Moghaddasi, Hamid Ahmadieh, Hamed Esfandiari

“…All nine rabbits were euthanized on day 14; the globes were stained with hematoxylin & eosin, Masson's Trichrome, and immunohistochemistry for detecting alpha-smooth muscle (α-SMA) actin. RNA extraction was performed on five eyes of the remaining rabbits which included one eye without any surgery, one eye 5 hr after trabeculectomy without any injection, one eye five days after trabeculectomy without any injection, and two eyes five days after trabeculectomy with administration of MMC and BSS, respectively. …”
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An untargeted metabolomic analysis of acute AFB1 treatment in liver, breast, and lung cells. by Heidi H Cao, Sabrina Molina, Susan Sumner, Blake R Rushing

“…Finally, analysis of treated MDA-MB-231 cells found spermidine and spermine biosynthesis, carnitine synthesis, plasma membrane-related pathways (phosphatidylcholine synthesis and alpha linolenic acid and linoleic acid metabolism), and various amino acid metabolism pathways to be most affected. …”
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The causal relationship between serum metabolites and the risk of psoriasis: a Mendelian randomization and meta-analysis study by Yujie Yang, Xuwei Zheng, Haiying Lv, Bin Tang, Bin Tang, Bin Tang, Bin Tang, Bin Tang, Yiyuan Zhong, Qianqian Luo, Yang Bi, Kexin Yang, Haixin Zhong, Haiming Chen, Haiming Chen, Haiming Chen, Haiming Chen, Haiming Chen, Chuanjian Lu, Chuanjian Lu, Chuanjian Lu, Chuanjian Lu, Chuanjian Lu

“…The metabolites associated with psoriasis risk in the two stages are mainly enriched in the following metabolic pathways: Glutathione metabolism, Alpha Linolenic Acid and Linoleic Acid Metabolism, Biosynthesis of unsaturated fatty acids, Arachidonic acid metabolism, Glycerophospholipid metabolism.ConclusionCirculating metabolites may have a potential causal relationship with psoriasis risk, and targeting specific metabolites may benefit psoriasis diagnosis, disease assessment, and treatment.…”
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Análisis multidimensional de la voz en usuarios con enfermedad de Parkinson: Un estudio de casos by Gerson Jara Cabrera, Carolina Peralta Castillo, Dafna Gallegos Lobos, Carlos Sepúlveda Ordiqueo, Paula Carrasco Currín, Cristianne Higuera Seguel, Catalina Gálvez Pino

“…Cuatro sujetos arrojaron un valor de shimmer aumentado y dos presentaron un aumento del nivel de ruido. La relación alpha ratio se encontraba con valores negativos en todos los participantes.  …”
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The Impact of Silymarin on Inflammation and Oxidative Stress: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Mahdi Vajdi, Shaghayegh Adeli, Arash Karimi, Vahid Asghariazar, Arezoo Moini Jazani, Ramin Nasimidoost Azgomi

“…The effect of silymarin on inflammation and oxidative stress was investigated using the keywords “milk thistle” OR “Silybum marianum” OR “Silybum” OR “silymarin” OR “Silibinin” AND “MDA” OR “Malondialdehyde” OR “TAC” OR “total antioxidant capacity” OR “IL-10” OR “Interleukin-10” OR “IL-6” OR “Interleukin-6” OR “TNF-α” OR “tumor necrosis factor alpha” on the Web of Science, Scopus, Embase, PubMed, and Cochrane Library, up until March 2023. …”
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Situational analysis of the quality of maternal, child, and adolescent health data in the health districts of Thiès, Mbour, Kédougou, and Saraya in Senegal by Fatoumata Binetou Diongue, Adama Faye, Cheikh Loucoubar, Ndèye Marème Sougou, Ibrahima Sy, Adama Tall, Youssoupha Ndiaye, Samba Cor Sarr

“…Data were collected using Performance of Routine Information Systems Management (PRISM) data collection tools and the ODK application and analyzed (univariate and bivariate) using R and Stata with an alpha risk of 5%. The following data quality indicators (accuracy, completeness, and promptness) were estimated. …”
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Distinctive Gut Microbiota Alteration Is Associated with Poststroke Functional Recovery: Results from a Prospective Cohort Study by Yini Dang, Xintong Zhang, Yu Zheng, Binbin Yu, Dijia Pan, Xiaomin Jiang, Chengjie Yan, Qiuyu Yu, Xiao Lu

“…Relationships between discriminant bacteria and poststroke functional outcomes were estimated. Results. Higher alpha diversity of gut microbiota was observed in poststroke patients as compared to the healthy controls (p<0.05). …”
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Modulatory effects of selenium nanoparticles on gut microbiota and metabolites of juvenile Nile tilapia (Oreochromis niloticus) by microbiome-metabolomic analysis by Jing Ni, Lirong Ren, Ying Liang, Ying Ma, Hejian Xiong

“…In group M, the growth-promoting intestinal metabolite alpha-tocotrienol was significantly upregulated, whereas some essential amino acids were significantly downregulated in groups Y and H. …”
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