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4421
Immunopathological Changes of Streptococcus pneumoniae Causing Respiratory Infection in Lambs
Published 2024-12-01“…The blood samples were collected from all animal groups at day zero before pneumoniae induction and 3, 6, and 14 days post infection for total and differential white blood cell count (WBCs) and tumor necrosis factor-alpha (TNF-α) assessments. Additionally, on days 6 and 14 post-exposure, trachea and lung tissue samples were harvested for macroscopic and microscopic pathological changes evaluation. …”
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4422
Chronic restraint stress affects the diurnal rhythms of gut microbial composition and metabolism in a mouse model of depression
Published 2025-01-01“…Results CRS mice exhibited depressive-like behaviours after 4 weeks of restriction. Alpha- and beta-diversity analyses revealed that the microbial composition in control and CRS mice oscillated throughout the day. …”
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4423
Simultaneous Pheochromocytoma, Paraganglioma, and Papillary Thyroid Carcinoma without Known Mutation
Published 2018-01-01“…Urine metanephrines was elevated. After preoperative alpha-blockade, patient underwent total right adrenalectomy. …”
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4424
Prognostic Value of CXCL13, CCL11, and CCL20 Chemokines in Multiple Sclerosis
Published 2024-12-01Subjects: “…macrophage inflammatory protein 3-alfa…”
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4425
Catheter ablation versus antiarrhythmic drugs with risk factor modification for treatment of atrial fibrillation: a protocol of a randomised controlled trial (PRAGUE-25 trial)
Published 2022-06-01“…An AF freedom of 65% in the RFM+AAD and of 60% in the CA is expected; therefore, 202 patients will be enrolled to achieve the non-inferiority with 80% power, 5% one-sided alpha and a non-inferiority margin of 12%.Ethics and dissemination The PRAGUE-25 trial will determine if modern non-invasive AF treatment strategies are non-inferior to CA. …”
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4426
A Research on Professıonal Anxıety Levels of 3and 4 Grade Students of Faculty of Sport Scıences of Selcuk Unıversıty
Published 2018-12-01“…For this study, the Cronbach Alpha coefficent was calculated as 0.88. Significance level in the study was taken as 0.05. …”
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4427
Isolation and Evaluation of Potential Use of Prebiotics—Utilizing Butyrate-Producing Bacteria in Nibea coibor
Published 2025-01-01“…Contents of IL-6 (PS and PSGS groups), tumor necrosis factor-alpha (TNF-α) (CB, PS, and PSGS groups), total antioxidant capacity (T-AOC) (CB and PS groups), total superoxide dismutase (T-SOD) (PS group), catalase (CAT) (CB and PSGS groups), and activities of amylase (PS and PSGS groups), trypsin (CB group), and lipase (CBIG group) were increased. …”
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4428
Regulation of miRNAs in obesity and diabetes
Published 2023-12-01“…Transforming Growth Factor-beta (TGF-β), Tumour Necrosis Factor-alpha (TNF-α) and Vascular Endothelial Growth Factor A (VEGFA) were differentially expressed across each of the cell cohorts investigated. …”
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4429
Systemic Inflammation and Oxidative Stress in Childhood Obesity: Sex Differences in Adiposity Indices and Cardiovascular Risk
Published 2024-12-01“…We also aimed to assess the potential of the interferon-inducible T-cell alpha chemoattractant (I-TAC/CXCL11) as a novel biomarker. …”
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4430
Knockdown of PTEN promotes colon cancer progression and induces M2 macrophage polarization in the colon cancer cell environment
Published 2023-07-01“…Si-PTEN reduced the expression of tumor necrosis factor-alpha (TNF-α), interleukin-1beta (IL-1β), and inducible nitric oxide synthase (iNOS), which upregulated the expression of Arg-1, CD206, CD163, p-p38, JNK, and AP-1 (P-values < 0.05). …”
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4431
Petrological controls on the engineering properties of carbonate aggregates through a machine learning approach
Published 2024-12-01“…., r = 0.998, R² = 997, Root mean square error = 0.075, Variance Accounted For = 99.50%, Mean Absolute Percentage Error = 0.385%, Alpha 20 Index = 100, and performance index = 0.975). …”
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4432
Instrumentos y escalas para medir la cultura organizacional: una revisión sistemática de la literatura en el período 2013-2023.
Published 2024-08-01“…El 92,8 % de los instrumentos analizados supera el Alpha de Cronbach de 0,70, y para la validación, el 85,7 % empleó la validez de constructo. …”
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4433
Development and Validation of the Pediatric Well-Being Picture Scale© Using a Mixed-Methods Research Design
Published 2025-01-01“…The test/retest reliability demonstrated strong correlations, with an ICC of 0.823 (95% CI [0.690, 0.905]). The Cronbach’s alpha for all the administrations was 0.74, 0.74, 0.84, and 0.89. …”
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4434
Cerebrospinal fluid metabolites as potential biomarkers for epilepsy: Insights from genome‐wide association studies
Published 2025-02-01“…After False Discovery Rate (FDR) multiple testing correction, two metabolites (Methylmalonate and Gamma‐glutamyl‐alpha‐lysine) were found to have robust causal links to epilepsy (p < 0.05 and FDR<0.05). …”
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4435
Tailored exercise and manual therapy versus standardised exercise for patients with shoulder subacromial pain: a feasibility randomised controlled trial (the Otago MASTER trial)
Published 2022-06-01“…Since this is a feasibility study, we did not adjust alpha for multiple comparisons, and considered 75% CI as the probability threshold at 3-month follow-up. …”
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4436
Comparison of Finasteride and Dutasteride on Risk of Prostate Cancer in Patients with Benign Prostatic Hyperplasia: A Pooled Analysis of 15 Real-world Databases
Published 2025-01-01“…Finasteride blocks only the type 2 form of 5-alpha-reductase, whereas dutasteride blocks both type 1 and 2 forms of the enzyme. …”
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4437
Distinct roles of Constitutive Photomorphogenesis Protein 1 homolog (COP1) in human hepatocyte models
Published 2025-02-01“…COP1 downregulation reduced hepatic nuclear factor-4 alpha (HNF4A) abundance and function, as assessed by a lower abundance of key HNF4A targets, reduced APOB secretion, and reporter assays. …”
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4438
Fatty Acid Profile and Chemical Composition of Three Populations of Southern Cattail (Typha domingensis) from South of Iran
Published 2025-01-01“…In roots and rhizomes, the maximum proportion of unsaturated fatty acids including oleic acid (ω-9), linoleic acid (ω-6), alpha- linolenic acid (ω-3) was 65.85±1.51%, whereas in stems and leaves, it was 41.10±0.09%. …”
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4439
Study of the neuroprotective properties of metformin in rats with type 2 diabetes mellitus and brain injury induced by intracerebral hemorrhage
Published 2024-06-01“…Histopathological examination was performed using general histological staining techniques and immunohistochemical methods for assessment of expression of endothelial NO-synthase (eNOS), Growth Associated Protein 43 (GAP43), Hypoxia-inducible factor 1-alpha (HIF-1α), neural cadherine (N-cadherine) and vascular endothelial cadherine (VE-cadherine). …”
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4440
Association between fluoride exposure and the risk of serum CK and CK-MB elevation in adults: a cross-sectional study in China
Published 2025-01-01“…This study found that there was a positive association between urinary fluoride concentration and the risk of CK-MB elevation in participants under the age of 60 years(OR = 2.18 [95% CI: 1.39–3.42]), those who were of female gender (OR = 1.53 [95% CI: 1.07–2.19]), those who were overweight/obese (OR = 1.96 [95% CI: 1.28–2.99]), those who had central obesity (OR = 1.59 [95% CI: 1.12–2.25]), consumed alcohol (OR = 1.49 [95% CI: 1.09–2.05]), and smoked (OR = 1.50 [95% CI: 1.10–2.04]).ConclusionOur study suggests that fluoride exposure is associated with the risk of serum CK and CK-MB elevation; however, it is not associated with myocardial ischemia, arrhythmia, serum lactate dehydrogenase (LDH), serum alpha-hydroxybutyrate dehydrogenase (α-HBD), or serum aspartate aminotransferase (AST). …”
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