Biomechanical Characteristics on the Lower Extremity of Three Typical Yoga Manoeuvres by Elizabeth Whissell, Lin Wang, Pan Li, Jing Xian Li, Zhen Wei

“…One-way repeated ANOVA was used in exploring the differences amongst the three yoga movements, and the significance was set to alpha<0.05. The triangle pose performed the largest range of motion (ROM) of the hip (90.5°±22.9°), knee (68.8°±23.1°), and ankle (46.4°±11.3°) in the sagittal plane and the hip (54.8°±6.5°), knee (42.4°±12.8°), and ankle (4.8°±1.7°) in the frontal plane amongst the three manoeuvres (P<0.05). …”
Get full text

Co-occurrence of entomopathogenic nematodes and earthworms enhances enduring biocontrol activity and microbial diversity in a naturalized plant-soil system by Maryam Chelkha, Rubén Blanco-Pérez, David Labarga, María de Toro, Jorge Dueñas-Hernani, Kyle Wickings, Raquel Campos-Herrera

“…Bacterial community changes were observed 30 days post-inoculation, with increased alpha diversity in co-applications of EPNs and EWs. …”
Get full text

Ghrelin Protects Lipopolysaccharide-Induced Acute Lung Injury Rats against Pulmonary Vascular Dysfunction by Inhibiting Inflammation by Guang Li, Chen-Liang Zhou, Wen-Fang Xia, Di Zhang, Hui-Qing Lin

“…Immunohistochemical staining to detect alpha-smooth muscle actin (α-SMA) and proliferating cell nuclear antigen (PCNA) expression was performed to assess the intrapulmonary arterial wall thickness and the proliferation of smooth muscle cells, respectively. …”
Get full text

Structural analysis of the impact of learning from errors and organizational failures on innovative performance with the mediation role of knowledge absorptive capacity (case study... by Sara Mohammadi, Farajallah Rahimi, Eslam Fakher, Ilnaz Irani Behbahani

“…The validity and reliability of these questionnaires were confirmed using content validity and Cronbach's alpha (above 0.7).Findings: The results of the structural equation modeling test using SmartPLS-3 software indicated that although learning from organizational errors has a direct and significant impact on innovative performance, it also leads to a greater increase in innovative performance through employees' absorptive capacity. …”
Get full text

AI-optimized electrochemical aptasensors for stable, reproducible detection of neurodegenerative diseases, cancer, and coronavirus by Amira Elsir Tayfour Ahmed, Th.S. Dhahi, Tahani A. Attia, Fawzia Awad Elhassan Ali, Mohamed Elshaikh Elobaid, Tijjani Adam, Subash C.B. Gopinath

“…Similarly, Square Wave Voltammetry (SWV) and potentiometric sensors have detected alpha-fetoprotein (AFP) at 5 fM and epithelial cell adhesion molecule (EpCAM) at 100 fM, respectively. …”
Get full text

Mesenchymal stem cell and exosome-based therapy for liver diseases: can it overcome conventional therapeutic inconsistencies? by Zahid Hussain

“…This process activates hepatic stellate cells and myofibroblasts to produce a huge quantity of collagens, alpha-smooth muscle actin, and extracellular matrix deposition in liver parenchyma. …”
Get full text

ÖRGÜT KÜLTÜRÜ ALGISININ ÖRGÜTSEL ÇEVİKLİK ÜZERİNDEKİ ETKİSİNİN İNCELENMESİ by Suzan Basrı, Kürşad Zorlu

“…Geçerlilik testi için doğrulayıcı faktör analizi, güvenilirlik için Cronbach’s alpha değerlerine bakılmıştır. Sonuç olarak dağılımın normal olduğu görülmüştür. …”
Get full text

PPARβ/δ Agonism with GW501516 Increases Myotube PGC-1α Content and Reduces BCAA Media Content Independent of Changes in BCAA Catabolic Enzyme Expression by Caroline N. Rivera, Jason S. Hinkle, Rachel M. Watne, Trent C. Macgowan, Andrew J. Wommack, Roger A. Vaughan

“…Type 2 diabetes is characterized by reduced insulin sensitivity, elevated blood metabolites, and reduced mitochondrial metabolism with reduced expression of genes governing metabolism such as peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α). PGC-1α regulates the expression of branched-chain amino acid (BCAA) metabolism, and thus, increased circulating BCAA in diabetics may be partially explained by reduced PGC-1α expression. …”
Get full text

Shenlian (SL) Decoction, a Traditional Chinese Medicine Compound, May Ameliorate Blood Glucose via Mediating the Gut Microbiota in db/db Mice by Rui-xi Sun, Wei-jun Huang, Yao Xiao, Dou-dou Wang, Guo-hua Mu, He Nan, Bo-ran Ni, Xiao-qiang Huang, Hsuan-chuan Wang, Yi-fan Liu, Qiang Fu, Jin-xi Zhao

“…In this study, results demonstrated that SL decoction had a better hypoglycemic effect and β cell protection effect than either ginseng or Coptis chinensis. Alpha diversity analysis showed that all interventions with ginseng, Coptis, and SL decoction could reverse the increased diversity and richness of gut microbiota in db/db mice. …”
Get full text

Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach by Genbao Zhu, Genbao Zhu, Genbao Zhu, Zhiming Jiang, Niuping Zhu, Niuping Zhu, Donghui Wang, Donghui Wang, Tianpeng Guo, Tianpeng Guo, Yiqing Meng, Yiqing Meng, Yi Zhu, Yi Zhu, Kemeng Tan, Mengxue Hu, Heng Tang, Xuannian Wang, Xuannian Wang

“…Lastly, in vitro experiments were performed for validation.ResultsA least of four key targets, namely BCL2 apoptosis regulator (BCL2), estrogen receptor 1 (ESR1), hypoxia-inducible factor 1 subunit alpha (HIF1A), and signal transducer and activator of transcription 3 (STAT3) were identified in this study, and molecular docking analyses revealed that SSA stably binds to these targets. …”
Get full text

Translation, cross-cultural adaptation and validation of the composite physical function scale in Chinese community-dwelling older adults by Jiaying Qi, Jing Xu, Hui Zhang, Mingshuai Feng, Hongyan Meng, Li Wang

“…Results The C-CPF was consistent with the original version, which consisted of a single dimension with 12 items. It had a Cronbach’s alpha coefficient of 0.901, fold-half reliability of 0.831 and test–retest reliability of 0.994. …”
Get full text

Exploring patient-centered barriers to hemophilia care in Southern Nigeria: Study Protocol by Eguzo K, Ekwere T, Kirikareye B, Okoye H, Egharevba P, Oluoha C

“…Whereas the average years in practice for the HCPs was 13±6 years and had encountered about 20 patients (IQR: 6, 32) with hematologic disorders in the previous month. A Cronbach's alpha of 0.92 (PLwH Survey) and 0.91 (HCP survey) was obtained for the surveys, indicating excellent internal consistency. …”
Get full text

Outcomes of COVID-19 in the Omicron-predominant wave: large-scale real-world data analysis with a comparison to influenza by Koichi Miyashita, Hironao Hozumi, Kazuki Furuhashi, Eiji Nakatani, Yusuke Inoue, Hideki Yasui, Yuzo Suzuki, Masato Karayama, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Toshiyuki Ojima, Takafumi Suda

“…Results The mortality rates (average number of deaths/cases per week) of COVID-19 decreased over time, being 2.7% (169/6312), 2.1% (397/18,754), 0.7% (195/28,273), and 0.4% (1613/378,848) in the wild-type–, Alpha-, Delta-, and Omicron-predominant waves, respectively. …”
Get full text

Factores determinantes en la calidad del servicio sanitario en México: Caso ABC by Norma Angélica Pedraza-Melo, Jesús Lavín-Verástegui, Anahí González-Tapia, Idolina Bernal-González

“…Para el análisis de fiabilidad de la escala se determinó el Alpha de Cronbach. Con base en el análisis factorial exploratorio se identificaron cinco factores que determinan la calidad de los servicios sanitarios en el hospital ABC. …”
Get full text

Sex differences in the neuroinflammatory signaling pathway: effect of miRNAs on fatty acid synthesis in microglia by Haolin Zheng, Akiko Mizokami, Sergio Romera-Giner, Jaime Llera-Oyola, Yosuke Yamawaki, Tomomi Sano, Eijiro Jimi, Francisco García-García, Takashi Kanematsu

“…Consequently, the suppression of FASN expression led to reduced expression and secretion of tumor necrosis factor-alpha following LPS stimulation in MG6 cells. Conclusions These findings suggest that testosterone modulates inflammation in male microglia by regulating fatty acid synthesis, potentially contributing to the observed sex differences in AD pathogenesis.…”
Get full text

Pipeline for development of acylated peptide based CGRP receptor antagonist with extended half-life for migraine treatment by Jens Bjelke Kristensen, Lisbeth Elster, Morten Lundh, Borja Ballarín-González, Flora Alexopoulou, Martin Kræmer, Ditte Marie Jensen, Ulrike Leurs, Jens Christian Nielsen, Henrik H. Hansen, Kristian A. Haanes, Matilda Degn

“…The disease has neurovascular origin and migraine attacks can be elicited by vasodilative neuropeptides such as alpha calcitonin gene-related peptide (αCGRP). Antagonizing CGRP actions in migraine patients has proven clinically efficient. …”
Get full text

Unveiling the potential of spirulina algal extract as promising antibacterial and antibiofilm agent against carbapenem-resistant Klebsiella pneumoniae: in vitro and in vivo study by Mohamed I. Selim, Tarek El-banna, Fatma Sonbol, Walaa A. Negm, Engy Elekhnawy

“…The current study aimed to investigate the effectiveness of the green algae Arthrospira maxima (commercially known as Spirulina) both in vitro and in vivo against carbapenem-resistant K. pneumoniae. …”
Get full text

Lecturers' teaching competencies towards improving teaching and learning process in universities in Tanzania: Students’ perspectives by Asia Mbwebwe Rubeba

“…The study's reliability was assessed using Cronbach Alpha in which content competency = 0.889, pedagogical competency = 0.809, assessment and evaluation skills = 0.701, and technological competency = 0.777 show acceptance of theoretical constructs. …”
Get full text

scRNA-seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria by Collins M. Morang’a, Riley S. Drake, Riley S. Drake, Riley S. Drake, Riley S. Drake, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Nancy K. Nyakoe, Dominic S. Y. Amuzu, Vincent Appiah, Yaw Aniweh, Yaw Bediako, Saikou Y. Bah, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Gordon A. Awandare, Thomas D. Otto, Lucas Amenga-Etego

“…On average, patients were characterized by a higher fractional abundance of monocytes and an upregulation of innate immune responses, including those to type I and type II interferons and tumor necrosis factor-alpha signaling via NFκB. Further, in the patients, we identified more putative interactions between antigen-presenting cells and proliferating CD4 T cells, and naïve CD8 T cells driven by MHC-I and MHC-II signaling pathways, respectively. …”
Get full text

Comparative mRNA Expression of eEF1A Isoforms and a PI3K/Akt/mTOR Pathway in a Cellular Model of Parkinson’s Disease by Kawinthra Khwanraj, Suriyat Madlah, Khwanthana Grataitong, Permphan Dharmasaroja

“…Previous studies in nonneuronal cells showed that Akt regulation can be increased by eukaryotic protein elongation factor 1 alpha 2 (eEF1A2). eEF1A2 is proposed to contribute protection against apoptotic death, likely through activation of the PI3K/Akt pathway. …”
Get full text