ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer by Pingping Su, Xiaodan Mao, Jincheng Ma, Lixiang Huang, Lirui Yu, Shuting Tang, Mingzhi Zhuang, Zhonglei Lu, Kelvin Stefan Osafo, Yuan Ren, Xinrui Wang, Xite Lin, Leyi Huang, Xiaoli Huang, Elena Ioana Braicu, Jalid Sehouli, Pengming Sun

“…Estrogen-related receptor alpha (ERRα) is a central regulator of cellular energy metabolism associated with poor cancer prognosis. …”
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Functional Tests and Surveys Used to Assess Nervous System Dysfunction in Patients with Fabry Disease – A Review by Stanislaw Jesionek, Jakub Parys, Agnieszka Mikosińska, Martyna Kaźmierczak, Partycja Kałuziak, Marta Jajczak, Maciej Mossakowski, Aleksandra Witek, Mateusz Litwin, Justyna Jankowska

“… Introduction and Purpose: Fabry disease (FD) is a rare, X-linked lysosomal storage disorder caused by a deficiency of the enzyme alpha-galactosidase A, leading to progressive multi-organ damage. …”
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Nicotinamide Ameliorates Dextran Sulfate Sodium-Induced Chronic Colitis in Mice through Its Anti-Inflammatory Properties and Modulates the Gut Microbiota by Kai Kang, Yue Sun, Dan Pan, Bing Chang, Li-Xuan Sang

“…Then, 16S rRNA sequencing of the large intestinal content was performed, and analysis of alpha diversity and beta diversity showed that the richness of the gut microbiota was decreased in the DSS group compared to the control group and restored after NAM treatment. …”
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Psychometric accuracy of the Dutch Child and Adolescent Trauma Screener by Lieke H. Kooij, Irma M. Hein, Cedric Sachser, Samantha Bouwmeester, Madelief Bosse, Ramón J. L. Lindauer

“…The KJTS showed excellent reliability (alpha = .92) on both selfreport and caregiver report. …”
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RHOBTB2 Variant p.Arg511Gln Causes Developmental and Epileptic Encephalopathy Type 64 in an Infant: A Case Report and Hotspot Variant Analysis by Qian Liu, Feifei Li, Qin Ruan, Nana Wang, Zhengjun Fan

“…We used Discovery Studio software to analyze the folding free energy of variant proteins, and the AlphaFold database to analyze structural alterations in mutant proteins. …”
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Acute and chronic effects of physical exercise on atherosclerosis, kynurenine pathway, endothelial function and inflammation in patients with coronary artery disease: a clinical tr... by Eliete Bouskela, Gabriela Andrade Paz, Marcus VDS Rangel, Caio Luan Farias, André Luiz Conveniente Soares, Erica Langner, Tatiana Teixeira, Patrícia M L Dutra, Paulo Farinatti, Maria das Graças C Souza, Juliana P Borges

“…Levels of KP metabolites (TRP, KYN, kynurenic acid and quinolinic acid), inflammatory cytokines (interleukin-6, tumour necrosis factor-alpha and interferon-gamma), T-cell subpopulations and soluble adhesion molecules (soluble P-selectin, soluble vascular cell adhesion molecule-1 and soluble intercellular adhesion molecule-1) will be assessed via ELISA, flow cytometry and multiplex assays, respectively. …”
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An Autonomous Underwater Vehicle Navigation Technique for Inspection and Data Acquisition in UWSNs by Arif Wibisono, Md. Jalil Piran, Hyoung-Kyu Song, Byung Moo Lee

“…Furthermore, in the inspection and data acquisition mission in UWSN simulated as node points (o) in pink, AUV (&#x002A;) in blue effectively follows the predetermined points while acquiring data, as indicated by green lines (-) within just 5 seconds, achievable by increasing the value of <inline-formula> <tex-math notation="LaTeX">$\alpha $ </tex-math></inline-formula> (angle of attack) of the target node to reduce delay time. …”
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Mechanism of dexmedetomidine protection against cisplatin induced acute kidney injury in rats by Zeng-lu Zheng, Jun-wei Ma, Yi Luo, Gui-jin Liang, Shi-jie Lei, Ke-jin Yan, Hai-bing Meng, Xiu-juan Liu

“…In addition, four serum biochemical indices were measured: histopathological damage in rat kidneys was detected; levels of inflammatory factors, interleukin (IL)-1β, IL-18, IL-6, and tumor necrosis factor alpha, in kidney tissue homogenate of rats were assessed through enzyme-linked immunosorbent assay (ELISA); and levels of NLRP-3, caspase-1, cleaved caspase-1, gasdermin D (GSDMD), and GSDMD-N in kidney tissues of rats were determined via western blotting.Results Dex treatment reduced nephromegaly and serum clinical marker upregulation caused by CP-induced AKI. …”
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A psychometric appraisal of a revised preparedness for medication administration questionnaire in final-year undergraduate nursing students: a secondary analysis by Susan Irvine, Sharon Andrew, Christina Aggar, Nicola Whiteing, Anecita Gigi Lim, Brett Williams

“…The final revised version of the questionnaire titled the Preparedness for Medication Administration Revision2 (PMAR2) contained 16 items loading onto one of the 2 factors titled Clinical Reasoning and Confidence to Practice Safely. Cronbach alpha coefficients for the factors were .89 to .95, respectively. …”
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Fenofibrate Protects Cardiomyocytes from Hypoxia/Reperfusion- and High Glucose-Induced Detrimental Effects by Fabiola Cortes-Lopez, Alicia Sanchez-Mendoza, David Centurion, Luz G. Cervantes-Perez, Vicente Castrejon-Tellez, Leonardo del Valle-Mondragon, Elizabeth Soria-Castro, Victoria Ramirez, Araceli Sanchez-Lopez, Gustavo Pastelin-Hernandez, Wylly Ramses Garcia-Niño, Maria Sanchez-Aguilar, Luz Ibarra-Lara

“…Fenofibrate, a peroxisome proliferator-activated receptor alpha (PPARα) agonist, promotes beneficial activities counteracting cardiac injury. …”
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The Role of Invariant NKT in Autoimmune Liver Disease: Can Vitamin D Act as an Immunomodulator? by Daniel S. Smyk, Athanasios Mavropoulos, Giorgina Mieli-Vergani, Diego Vergani, Marco Lenzi, Dimitrios P. Bogdanos

“…CD1d-restricted iNKT cells are regulators of immune responses and produce cytokines that may be proinflammatory (such as interferon-gamma (IFN-γ)) or anti-inflammatory (such as IL-4). iNKT cells also appear to play a role in B cell regulation and antibody production. Alpha-galactosylceramide (α-GalCer), a derivative of the marine sponge, is a potent stimulator of iNKT cells and has been proposed as a therapeutic iNKT cell activator. …”
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Explainable correlation-based anomaly detection for Industrial Control Systems by Ermiyas Birihanu, Imre Lendák

“…This is achieved through an anomaly detection module that incorporates a threshold mechanism, utilizing alpha and epsilon values. The proposed method utilizes a novel set of input features extracted using the Shapley Additive explanation (SHAP) framework to train and evaluate the MGD model. …”
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Concepciones acerca del aprendizaje: diseño y validación de un cuestionario para profesores en formación by Silvia L. Vilanova, María B. García, Orlanda Señoriño

“…Para determinar la fiabilidad del análisis factorial y en consecuencia, la validez de constructo, se utilizó el Alpha de Cronbach. El posterior análisis de los datos muestra el uso de la teoría interpretativa del aprendizaje, basada en una concepción epistemológica vinculada con el realismo crítico.…”
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A New Functional Model for Prediction of Chaperone Activity of the Recombinant M. tb Acr (α-Crystallin) Using Insulin as Substrate by Gautam Krishnan, Utpal Roy

“…In this study, Mycobacterium alpha crystallin (acr) gene was cloned and expressed in Escherichia coli (E. coli). …”
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Establishment of a Southern catfish (Silurus meridionalis) spermatogonial stem cell line capable of sperm production in vitro by Jianeng Li, Changle Zhao, Lei Liu, Shuqing Zheng, Deshou Wang, Changwei Shao, Jing Wei

“…It exhibited expression of germ cell markers, including glial cell-derived neurotrophic factor family receptor alpha-1 (gfrα1) a and b, pou5f3, nanog, and vasa, but no expression of somatic cell markers such as amh, wt1a, and wt1b. …”
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Turning Noise Into Data: Characterization of the Van Allen Radiation Belt Using SDO Spikes Data by Spiridon Kasapis, Barbara J. Thompson, Juan V. Rodriguez, Raphael Attie, Gonzalo Cucho‐Padin, Daniel daSilva, Meng Jin, William D. Pesnell

“…As a result, we find that AIA spikes are highly correlated with the GOES‐14 electrons detected by the magnetospheric electron detector and energetic proton, electron and alpha detectors instruments at the equator (where the two satellites meet) with Spearman's Correlation values of ρ = 0.73 and ρ = 0.53, respectively, while a weaker correlation of ρ = 0.47 is shown with magnetospheric proton detector protons for the 2 year period where both missions returned data uninterruptedly. …”
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Frequency-specific changes in prefrontal activity associated with maladaptive belief updating in volatile environments in euthymic bipolar disorder by Marina Ivanova, Ksenia Germanova, Dmitry S. Petelin, Aynur Ragimova, Grigory Kopytin, Beatrice A. Volel, Vadim V. Nikulin, Maria Herrojo Ruiz

“…On a neural level, while healthy individuals exhibited an alpha-beta suppression and gamma increase during belief updating, BD participants showed dampened effects, extending across the PFC, OFC, and ACC regions. …”
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Stress factors among physiotherapy students at a university in Gauteng, South Africa by Zander I. Collins, Chané Siepker, Kelebogile J. Ralehlaka, Boitshoko C. Molefe, Tiisetso C. Phala, Simphiwe A. Vilankulu, Makwena M. Sibuyi, Thembelihle S. Ntuli

“…Data were collected through an online anonymised self-administered questionnaire. The Cronbach alpha coefficients for each subscale were 0.99 for physical, 0.72 for interpersonal relationships, 0.85 for academic and 0.81 for environment. …”
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16S rRNA sequencing-based evaluation of the protective effects of key gut microbiota on inhaled allergen-induced allergic rhinitis by Yi Tang, Yongchuan She, Danping Chen, Yibo Zhou, Dan Xie, Zhai Liu

“…Microbial diversity was assessed using alpha and beta diversity indices, and differential microbiota populations were identified through Linear discriminant analysis Effect Size (LEfSe) analysis. …”
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Re-presentations to the emergency department initial presentation with COVID-19: Insights from the omicron wave by Daniella Audish, George Braitberg, Anselm Wong

“…Conclusion: Re-presentation rates were similar to previous COVID waves with the alpha and delta variants. Respiratory symptoms and related diagnoses were common. …”
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