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3961
Structural basis for the interaction between the Drosophila RTK Sevenless (dROS1) and the GPCR BOSS
Published 2025-01-01“…Our mutagenesis studies, coupled with AlphaFold complex predictions, support a binding interaction mediated by a hydrophobic interaction and beta-strand augmentation between these regions. …”
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3962
Presenting an Evaluation Model of Digital Libraries (Iran)
Published 2025-01-01“…Based on the statistical findings of Cronbach's alpha, convergent validity, reliability coefficient, variance, standard deviation, and pebble diagrams with exploratory factor analysis by rotating the set according to the internal correlation between the items, 13 components were obtained in each element of the item, with significant correlations. …”
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3963
Peptide nucleic acid (PNA) clamps reduce amplification of host chloroplast and mitochondria rRNA gene sequences and increase detected diversity in 16S rRNA gene profiling analysis...
Published 2025-01-01“…In root tissues, where host oak chloroplast and mitochondria contamination were low, alpha and beta diversity did not change, suggesting the PNA clamps did not bias the bacterial community. …”
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3964
Comparative Analyses of Diversity and Similarity Indices of West Bank Forest and Block A Forest of the International Institute of Tropical Agriculture (IITA) Ibadan, Oyo State, Nig...
Published 2020-01-01“…West bank forest had higher values of all the diversity indices and Gamma diversity except Margalef’s community diversity index and alpha diversity index which were high in block A forest. …”
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3965
Precision fetal cardiology detects cyanotic congenital heart disease using maternal saliva metabolome and artificial intelligence
Published 2025-01-01“…Pathway analysis showed significant alterations in Arachidonic Acid, Alpha-linoleic acid, and Tryptophan metabolism indicating significant lipid dysfunction in cyanotic CHD. …”
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3966
Promoting ER stress in a plasmacytoid dendritic cell line drives fibroblast activation
Published 2025-02-01“…Results Direct contact of CAL-1 and IMR-90 cells under ER stress conditions led to increased expression of fibronectin and alpha-smooth muscle actin (α-SMA). This effect required expression of the ER stress signaling sensor protein kinase R-like ER kinase (PERK) in pDCs and was observed only upon direct contact between both cell types. …”
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3967
The Impact of Green Human Resource Management on IT Employees’ Environmentally Eco-friendly Performance and Behavior: The Mediating Role of Organizational Commitment
Published 2025-02-01“…Data normality and questionnaire internal consistency and reliability were assessed measuring Chronbach’s alpha statistic, which reveals the data were normally distributed, and the questionnaire maintained internal consistency and reliability. 500 valid responses were analyzed and four reflective constructs, organizational commitment, green human resource management, organizations’ environmental performance, and employees’ eco-friendly behavior, were assessed via exploratory, confirmatory factor analysis, and hypotheses were tested via structural equation modeling analysis. …”
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3968
The relaxant effect of Tamsulosin in the vascular reactivity of goat isolated renal artery
Published 2019-08-01“…Alpha-blockers including tamsulosin, are medications that relax muscles in the urinary tract to facilitate stone passage into the bladder. …”
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3969
Examining the impact of environmental product innovation on perceived brand value considering the mediating role of ethical- aspects in the home appliance industry
Published 2025-02-01“…To collect data, a standardized questionnaire was used, whose validity was confirmed by calculating content, convergent, and divergent validity, and its reliability was confirmed through the Cronbach's alpha index. In statistical analysis, the structural equation modeling approach was used.Findings: Based on the research results, environmental product innovations have a positive and significant impact on perceived brand value, open-mindedness, and customer privacy. …”
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3970
Achieving chronic hepatitis B functional cure: Factors and potential mechanisms
Published 2025-01-01“…Achieving the loss of hepatitis B surface antigen (HBsAg), either with or without seroconversion to hepatitis B surface antibody (HBsAb), is regarded as a functional cure and the optimal goal for addressing CHB, and can be achieved through various approaches, including induction with nucleos(t)ide analogues (NAs), induction with pegylated interferon alpha (PegIFNα), and spontaneous clearance of HBsAg. …”
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3971
Serum Neuropeptide Y Levels Are Associated with TNF-α Levels and Disease Activity in Rheumatoid Arthritis
Published 2020-01-01“…Therefore, we evaluate if NPY levels are markers of disease activity in RA and if there is a correlation between NPY levels and tumor necrosis factor-alpha (TNF-α), leptin, and interleukin 6 (IL-6) levels. …”
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3972
Obesity and Cytokines in Childhood-Onset Systemic Lupus Erythematosus
Published 2014-01-01“…To evaluate the association between obesity, measures of body fat content, serum tumor necrosis factor alpha (TNF-α), and interleukin (IL)-6 and -10 levels in childhood-onset SLE (cSLE). …”
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3973
Case Report: Nephrotic syndrome as the primary manifestation of Alport syndrome in a Chinese pediatric patient
Published 2025-01-01“…BackgroundAlport syndrome (AS) is a genetically heterogeneous disorder resulting from variants in genes coding for the alpha-3/4/5 chains of Collagen IV, leading to defective basement membranes in the kidney, cochlea, and eye. …”
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3974
Osteoblast-Specific Overexpression of Nucleolar Protein NO66/RIOX1 in Mouse Embryos Leads to Osteoporosis in Adult Mice
Published 2023-01-01“…Here, we generated osteoblast-specific transgenic mice overexpressing a FLAG-tagged NO66 transgene driven by the 2.3 kB alpha-1type I collagen (Col1a1) promoter. We found that overexpression of NO66 in cells of the osteoblast lineage did not cause overt defects in developmental bones but led to osteoporosis in the long bones of adult mice. …”
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3975
Testcross performance of Striga-resistant maize inbred lines and testers with varying levels of Striga reaction
Published 2024-04-01“…The experiment was laid out in a 23 × 4 alpha-lattice design with two replications in each location. …”
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3976
In vitro comparison of the marginal adaptation of cold ceramic sealer with the single-cone obturation technique versus AH-26 sealer with the lateral compaction technique in single-...
Published 2025-01-01“…Comparisons were made by the Mann‒Whitney test (alpha = 0.05). Results The mean linear distance (gap) was significantly smaller in the CC sealer/single-cone group than the AH-26/lateral compaction group (6.72 ± 2.57 vs. 12.94 ± 4.82 μm, P = 0.001). …”
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3977
Assessing the quality of life in informal settlements in Miandoab
Published 2024-09-01“…The validity of the instrument and its reliability were confirmed by Cronbach's alpha greater than 0.70. The statistical population of the study consists of 11545 citizens living in informal settlements in Miandoab. …”
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3978
Relationship of Dietary Intake of Omega-3 and Omega-6 Fatty Acids with Risk of Prostate Cancer Development: A Meta-Analysis of Prospective Studies and Review of Literature
Published 2012-01-01“…A significant negative association between high dietary intake of alpha-linolenic acid (ALA) and prostate cancer risk (pooled RR: 0.915; 95% CI: 0.849, 0.985; ) was noted. …”
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3979
Mechanical properties and durability against the dry termite attacks of particleboard made from bamboo with citric acid as adhesive
Published 2015-03-01“…Chemical characteristics of petung bamboo were analyzed for its extractive, lignin, holocellulose and alpha cellulose. Factors used in this research were citric acid content (0 - 40 %) based on dry weight particles and pressing temperature (200 oC dan 220 oC). …”
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3980
In silico characterisation of the avocado WAK/WAKL gene family with a focus on genes involved in defence against Phytophthora cinnamomi
Published 2025-01-01“…The predicted proteins from these genes were modelled with AlphaFold2, and structural similarity across different rootstocks, as well as their binding affinity for oligogalacturonides, were assessed. …”
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