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3441
Hypercalcemia in Lung Cancer due to Simultaneously Elevated PTHrP and Ectopic Calcitriol Production: First Case Report
Published 2017-01-01“…We believe that the elevated calcitriol levels in this case were due to a PTHrP-independent mechanism, possibly from either ectopic production of calcitriol in tumor cells or from increased activity of 1-alpha hydroxylase in the same cells. The patient died before the effects of prednisone therapy could be assessed. …”
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3442
Yield Function of the DOSimetry TELescope Count and Dose Rates Aboard the International Space Station
Published 2021-05-01“…To describe the observations in such a complex radiation field, we follow the method by Caballero‐Lopez and Moraal (2012, Journal of Geophysical Research, 117[A12], A12103. doi:10.1029/2012JA017794) to compute the so‐called yield function using precise measurements of the proton and helium energy spectra obtained by alpha magnet spectrometer and the systematic variation of the DOSTEL measurements within the Earth's magnetosphere.…”
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3443
Differential Circulating Fungal Microbiome in Prostate Cancer Patients Compared to Healthy Control Individuals
Published 2022-01-01“…The fungal community in the plasma exhibited differences between individuals with PCa and healthy controls according to the beta diversity; there was no difference in the alpha diversity. Moreover, the relative abundance of several fungi differed between the two study groups from the class to species levels. …”
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3444
Evaluation of the effect of physical-environmental factors of public spaces on the mental health of citizens (Case study: Ardabil city)
Published 2020-12-01“…The field data collection tool was a researcher-made questionnaire whose validity was confirmed by formal validity and reliability using Cronbachchr('39')s alpha test and combined reliability. The results of this study showed that legibility and visual quality, access to urban green space, security of urban space, quality of urban furniture, mixing and variety of uses have a positive and significant effect on the mental health of citizens. …”
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3445
Intrathecal Resiniferatoxin Modulates TRPV1 in DRG Neurons and Reduces TNF-Induced Pain-Related Behavior
Published 2017-01-01“…Previous studies suggest interactions between tumor necrosis factor- (TNF-) alpha and TRPV1, resulting in a modulation of ion channel function and protein expression in sensory neurons. …”
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3446
Facilitators’ perspective towards implementation of Competency Based Medical Education (CBME) in a Government Medical College in Delhi: a cross-sectional study
Published 2025-02-01“…Data were collected using a validated self-developed questionnaire (Cronbach's alpha: 0.85). Results The median age of the faculty members was 42 years, with a median teaching experience of 10 years. …”
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3447
Molecular phylogeny of Cytospora species associated with canker diseases of fruit and nut crops in California, with the descriptions of ten new species and one new combination
Published 2018-12-01“…In this study, we employed a molecular phylogenetic framework with the inclusion of four nuclear loci (ITS, translation elongation factor 1-alpha, actin, and beta-tubulin) to unveil the biodiversity and taxonomy of this understudied important genus of plant pathogens. …”
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3448
Increased Nuclear Transporter KPNA2 Contributes to Tumor Immune Evasion by Enhancing PD-L1 Expression in PDAC
Published 2021-01-01“…Tumor immune evasion is a major stumbling block in designing effective anticancer therapeutic strategies. Karyopherin alpha 2 (KPNA2), a member of the nuclear transporter family, is elevated in multiple human cancers and accelerates carcinogenesis. …”
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3449
Dynamical systems of modified Gauss–Bonnet gravity: cosmological implications
Published 2025-01-01“…The cosmological implications are studied in $$f(R,G)=f_0R^nG^{1-n}$$ f ( R , G ) = f 0 R n G 1 - n and $$f(R,G)=f_0R^\alpha +f_1G^\beta $$ f ( R , G ) = f 0 R α + f 1 G β models to identify the qualitative evolution of universe with the flat-FRW spacetime. …”
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3450
Benchmarking of a time-saving and scalable protocol for the extraction of DNA from diverse viromes
Published 2025-01-01“…Most viral operational taxonomic units (vOTUs) were common to both methods, with only a small percentage unique to either approach. Alpha- and beta-diversity analyses showed no significant impact of the extraction method on virome composition, confirming the kit’s efficacy and versatility on sample types beyond those officially supported by the manufacturer. …”
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3451
Recent advances in nanotechnology for Parkinson’s disease: diagnosis, treatment, and future perspectives
Published 2025-01-01“…This review provides insights into the pathophysiology of Parkinson’s disease, highlighting the mechanisms of neurodegeneration, the role of alpha-synuclein, and the disruption of dopaminergic pathways. …”
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3452
Deciphering the fungal symphony: unveiling the fungal dynamics during the fermentation of traditional Chinese strong-flavor Daqu
Published 2025-01-01“…The results showed that the alpha and beta diversity of fungal community were significantly different during Daqu fermentation. …”
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3453
Spousal Presence as a Nonpharmacological Pain Management during Childbirth: A Pilot Study
Published 2015-01-01“…Internal consistency for the three questionnaires indicated Cronbach’s alpha coefficient of 0.789 (AIM), 0.802 (AIPP), and 0.860 (AIPS), while test-retest reliability was r=0.99 (AIM), r=0.99 (AIPP), and r=0.90 (AIPS). …”
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3454
Liver Transplantation for Liver-Originated Malignancy: A Single Center Experience
Published 2024-07-01“…Demographic characteristics, etiology, alpha-fetoprotein (AFP) levels, Milan Criteria compliance, pre-transplant treatments, complications, recurrence, and mortality were analyzed. …”
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3455
Intensive Treatment of Cellulite Based on Physiopathological Principles
Published 2012-01-01“…The paired t-test was utilized for statistical analysis with an alpha error of 5% (P value < 0.05). A reduction was identified at all of the measurement points (paired t-test; P value < 0.0001). …”
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3456
Flakka-Induced Prolonged Psychosis
Published 2016-01-01“…In South Florida, there has been a highly addictive new synthetic drug flooding the streets for people looking for a cheap high. Alpha-PVP, better known as Flakka, is an illegal substance that sells on the streets for as little as $5 a hit and delivers an instant high that can last from hours to days with lingering effects for weeks after it has been ingested. …”
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3457
The relationship between mindfulness, work-related stress management, and job satisfaction in a sample of Italian correctional officers
Published 2023-12-01“…Subsequently, reliability analyses were performed using Cronbach's alpha. Finally, a simple mediation analysis was conducted to define the role of work-related stress management, and the direct, indirect, and total effects were calculated. …”
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3458
Validation of the Persian Translation of the Swallowing Disturbance Questionnaire in Parkinson’s Disease Patients
Published 2014-01-01“…Aspiration during VFSS was compared with questionnaire results for each individual. Cronbach’s alpha coefficient for the questionnaire was 0.86 and based on SDQ-P 15 patients (25.4%) were dysphagic, while 10 patients (16.9%) showed aspiration during VFSS. …”
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3459
Identifying enablers for a circular healthcare supply chain: An integrated fuzzy DEMATEL-MMDE approach with hesitant information
Published 2025-02-01“…This paper identifies the enablers of a circular healthcare supply chain (CHSC) through a comprehensive analysis of cause and effect, interrelationships, and priorities using integrated alpha-level sets based on the fuzzy DEMATEL-MMDE approach with hesitant information. …”
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3460
Role of Heme Oxygenase in Inflammation, Insulin-Signalling, Diabetes and Obesity
Published 2010-01-01“…A common denominator of these chronic conditions is the enhanced the levels of cytokines like tumour necrosis factor-alpha (TNF-α), interleukin (IL-6), IL-1β and resistin, which in turn activates the c-Jun-N-terminal kinase (JNK) and NF-κB pathways, creating a vicious cycle that exacerbates insulin resistance, type-2 diabetes and related complications. …”
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