A randomized controlled interventional study for analgesic effects of intrathecal versus intravenous dexmedetomidine on subarachnoid anesthesia with hyperbaric bupivacaine by Manu Dadhwal, Anupama Gupta, Ajay Kurian

“…Background: Various pharmacologic agents such as opioids, benzodiazepines, ketamine, and alpha2 adrenergic agonists are commonly used to increase the duration of subarachnoid block. …”
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Infusion of Autologous Retrodifferentiated Stem Cells into Patients with Beta-Thalassemia by Ilham Saleh Abuljadayel, Tasnim Ahsan, Huma Quereshi, Shakil Rizvi, Tamseela Ahmed, Sabiha Mirza Khan, Jawaid Akhtar, Ghazi Dhoot

“…This results in excess accumulation of unpaired alpha-chain gene products leading to reduced red blood cell life span and the development of severe anemia. …”
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Communicative health literacy with physicians in healthcare services– results of a Hungarian nationwide survey by Frederico Epalanga Albano Israel, Ferenc Vincze, Róza Ádány, Éva Bíró

“…Results Both the value of Cronbach’s alpha and the Spearman-Brown correlation were 0.87. …”
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Identification of common and specific fibrosis-related genes in three common chronic kidney diseases by Zhangning Fu, Xiaodong Geng, Chao Liu, Wanjun Shen, Zheyi Dong, Guannan Sun, Guangyan Cai, Xiangmei Chen, Quan Hong

“…Quantitative real-time PCR (qRT-PCR) was performed to validate the expression of the selected genes.Results Protein tyrosine phosphatase receptor type C (PTPRC), intercellular cell adhesion molecule-1 (ICAM1), vascular cell adhesion molecule-1 (VCAM1), interleukin 10 receptor alpha (IL10RA) and CC chemokine receptor 2 (CCR2) were identified as the potential common genes for kidney fibrosis in different types of CKD, while peroxisome proliferator-activated receptor alpha (PPARA), lactate oxidase (LOX), secreted phosphoprotein 1 (SPP1) were identified as the specific fibrosis-associated genes for DN, IgAN and MN respectively. qRT-PCR demonstrated that the expression levels of these selected genes were consistent with the NanoString analysis.Conclusions There were both commonalities and differences in the mechanisms of fibrosis in different types of CKD, the commonalities might be used as the common therapeutic targets for kidney fibrosis in CKD, while the differences might be used as the diagnostic markers for DN, IgAN and MN respectively. …”
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Factores asociados al conocimiento sobre la COVID-19 y salud mental en médicos residentes by Christian Mejía, Fiorella Inga-Berrospi, José Antonio Grández-Urbina, Marcos Saavedra-Velasco, Rainer Echeverría-Ibazeta, Renzo Peñalva-Saji, Palmer José Hernández-Yépez

“…Se empleó la escala "Perception of Knowledge in Health Workers" (alpha de Cronbach: 0,77). También, se empleó la escala "Mental Health COVID-19" (alpha de Cronbach: 0,88). …”
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Different Approaches to requesting Consent for Routine data linkage in Neonatal follow-up (ACORN): protocol for a 2×2 factorial randomised trial by Jane E Harding, Barry Milne, Jenny Rogers, Greg Gamble, Jane Marie Alsweiler, Christopher McKinlay, Gavin Brown, Aakash Bajirao Rajay, Caroline Anne Crowther, Nike Franke, Trecia Wouldes

“…A pilot study indicates the potentially available cohort size of 2110 (80% follow-up of the neonatal trial cohorts) would be adequate to detect an absolute difference of 6%–5%–4% from a baseline consent rate of 70%–85%–90%, respectively (2-tailed alpha 0.05, 90% power). With at least 1136 participants, the ACORN trial would have 90% power to detect an absolute difference of 5% in the primary outcome for each factor, assuming a consent rate of 90% in the control groups and alpha 0.05. …”
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Chemical Constituents, Antioxidant Activities, and Element Concentrations of Rusa Deer Velvet Antler Extracts by Chutima Limmatvapirat, Potcharet Rodhetbhai, Krittaphas Somsakraksanti, Pitcha Danpongprasert, Soranun Poonsub, Wantanwa Krongrawa, Sontaya Limmatvapirat, Maneerat Meepan

“…In TLC, FTIR, 1H NMR, and HPLC analysis, HE and EE showed the presence of oleic acid, linoleic acid, alpha-linolenic acid, and testosterone. EE showed the highest concentration of testosterone and the strongest antioxidant activity in DPPH and FRAP assays. …”
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Survey of factors affecting religious beliefs in physical education students by Mohammadbagher Forghani Ozrudı, Somayeh Rahimi Alıabadı

“…Its validity and reliability was obtained (α=0.82) by using Cronbach Alpha test. The results showed that the impact of family, University environment, instructors' educational method, University teachers' performance, and community may greatly affect the internalization of religious values in students.…”
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Morphological and phylogenetic analyses reveal two new species of the Fusarium fujikuroi (Hypocreales, Nectriaceae) species complex in China by Mingwei Zhang, Cheng Peng, Shuji Li, Chengming Tian

“…We employ morphological and phylogenetic analyses based on partial gene fragments of the translation elongation factor 1-alpha (tef1), beta-tubulin (tub2), calmodulin (CaM), RNA polymerase largest subunit (rpb1), and RNA polymerase II second largest subunit (rpb2), as well as the pairwise homoplasy index tests. …”
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Homocysteine May Involve in the Pathogenesis of Behcet's Disease by Inducing Inflammation by Selda Pelin Kartal Durmazlar, Ahmet Akgul, Fatma Eskioglu

“…Untreated 70 patients with BD and 33 healthy individuals were included into the study. Hcy, tumor necrosis alpha (TNF-𝛼), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) were evaluated with respect to activity and specific individual clinical manifestations of the disease. …”
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Primary orbital yolk sac tumor in an infant: A rare entity by Varsha Mishra, Sandeep Jain, Payal Malhotra, Garima Durga, Gauri Kapoor

“…Biopsy of the lesion revealed pure YST histology. Serum alpha-fetoprotein (AFP) was markedly raised at 76900 ng/mL. …”
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Cytokines and Liver Diseases by Herbert Tilg

“…Among the various cytokines, the proinflammatory cytokine tumour necrosis factor-alpha (TNF-a) has emerged as a key factor in various aspects of liver disease, such as cachexia and/or cholestasis. …”
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The development of Anthropocene Awareness Scale. by Donghun Kang, Moon Choi

“…After a series of reliability and factor analyses, the Anthropocene Awareness Scale was optimized into a unidimensional scale comprising eight items (Cronbach's alpha = 0.88). Designed to explore individual attitudes, the scale could provide quantitative researchers with an entry point into the Anthropocene discourse and facilitate empirical studies that generate evidence for environmental policies and education in the Anthropocene.…”
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Fiber-optic system for monitoring stability of quarry slopes by P. Sh. Madi, А. D. Аlkina, A. V. Yurchenko, A. D. Mekhtiyev, R. Zh. Aimagambetova

“…The experimental data obtained are processed using the Wolfram Alpha computer program. A hardware-software control complex has also been developed with a wide range of elements that allows you to adjust sensitivity and has machine learning elements.…”
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Characterization and comparison of gut microbiota in patients with acute pancreatitis by metagenomics and culturomics by Liang Gong, Xue Li, Li Ji, Guorong Chen, Ziying Han, Lei Su, Dong Wu

“…Compared to healthy controls, patients with AP exhibited a significant decrease in alpha diversity; a higher abundance of unclassified Enterococcus species (sp), Enterococcus faecium, and Enterococcus faecalis; and a lower abundance of Eubacterium rectale. …”
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Two novel species of Aspergillus section Nigri from indoor air by Željko Jurjević, Stephen W. Peterson, Gaetano Stea, Michele Solfrizzo, János Varga, Vit Hubka, Giancarlo Perrone

“…To describe the species we used phenotypes from 7-d Czapek yeast extract agar culture (CYA), creatine agar culture (CREA) and malt extract agar culture (MEA), with support by molecular analysis of the β-tubulin, calmodulin, RNA polymerase II (RPB2), and translation elongation factor-alpha (TEF) gene amplified and sequenced from 56 air isolates and one isolate from almonds belonging to Aspergillus section Nigri. …”
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Salivary Biomarkers: Noninvasive Ways for Diagnosis of Parkinson’s Disease by Sanaz Salaramoli, Hamid Reza Joshaghani, Seyed Isaac Hashemy

“…The salivary concentration of DJ-1 and alpha-amylase is lower in PD patients. Also, substance P level is more moderate in PD patients. …”
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Potential anti-ageing effects of probiotic-derived conditioned media on human skin cells by Hong Yoo Kyung, An Sungkwan, Lee Yun Hee, Yang Seung Ah, Yoon Yoo Kyung, Lee Joonil, Lee Gwasoo, Chung Myung Jun, Bae Seunghee

“…Further exa mination of potential anti-pigmentation effects revealed that the B. lactis-derived conditioned media significantly inhibited tyrosinase activity and alpha-melanocyte-stimulating hormone-induced melanin production in human epidermal melanocytes. …”
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Masked Hypotension due to Elevated Venous Pressure in a Patient with Complex Adult Congenital Heart Disease by Wytch Rigger, Sean P. Javaheri, Gyanendra K. Sharma, Norris Stanley Nahman, Mark Sheynshteyn, Neal L. Weintraub

“…After reversible causes of low SVR state were excluded, the patient was successfully managed with oral alpha-adrenergic agents. While typically negligible under physiologic conditions, elevated CVP can artificially increase mean arterial pressure. …”
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Structural model of a bacterial focal adhesion complex by Christian Cambillau, Tâm Mignot

“…In this study, we utilize AlphaFold to generate models based on the known interactions and dynamics of gliding motility proteins. …”
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