Dietary protein requirement of Chinese hook snout carp (Opsariichthys bidens) and transcriptomic analysis of the liver in response to different protein diets by Yijiang Bei, Linqiang He, Jin Jing, Xiaoming Chen, Fan Yuan, Gaohua Yao, XueYan Ding, Lei Wang, Fan Zhou

“…., carboxypeptidases, elastase 2, trypsin-2, and bile salt-activated lipase) and immune response (e.g., NF-kappa B inhibitor alpha, tumor necrosis factor alpha-induced protein 3, complement C3, and C7) were significantly upregulated in the P47 group. …”
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The value of MRI in differentiating ovarian clear cell carcinoma from other adnexal masses with O-RADS MRI scores of 4–5 by Lingling Lin, Le Fu, Huawei Wu, Saiming Cheng, Guangquan Chen, Lei Chen, Jun Zhu, Yu Wang, Jiejun Cheng

“…CA125, HE4, CEA, ROMA, endometriosis, shape, parity, unilocular, component, the growth pattern of mural nodules, high signal on T1WI, number of nodules, the ratio of signal intensity, and the ADC value were significantly different between CCCs and non-CCCs. The kappa and interobserver correlation coefficient of each MRI feature exceeded 0.85. …”
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UHPLC-QTOF-MS/MS profiling, molecular networking, and molecular docking analysis of Gliricidia sepium (Jacq.) Kunth. ex. Walp. stem ethanolic extract and its gastroprotective effect on gastritis in rats by Aya A. Wafaey, Seham S. El-Hawary, Osama G. Mohamed, Sahar S. Abdelrahman, Alaa M. Ali, Ahmed A. El-Rashedy, Mohamed F. Abdelhameed, Farid N. Kirollos

Subjects: “…Gliricidia sepium (Jacq.) Kunth. ex. Walp.…”
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RETRACTED: Long non‐coding RNA Sox2OT promotes coronary microembolization‐induced myocardial injury by mediating pyroptosis by Liying Xuan, Danni Fu, Dong Zhen, Dongsong Bai, Lijun Yu, Guohua Gong

“…Results Rat CME disrupted the cardiac functions and induced inflammatory responses and oxidative stress, and activated the nuclear factor‐kappa B (NF‐κB) pathway and pyroptosis (all P < 0.05). …”
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Ultra-low dose dual-layer detector spectral CT for pulmonary nodule screening: image quality and diagnostic performance by Li Ding, Mingwang Chen, Xiaomei Li, Yuting Wu, Jingxu Li, Shuting Deng, Yikai Xu, Zhao Chen, Chenggong Yan

“…Quantitative and qualitative image analysis, nodule detectability, and Lung-RADS evaluation were compared using repeated one-way analysis of variance, Friedman test, and weighted kappa coefficient. Results A total of 249 participants (mean age ± standard deviation, 50.0 years ± 12.9; 126 male) with 637 lung nodules were included. …”
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Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa) by Jinhua He, Geng Zhao, Mingxia Chen, Ximing Ren, Peizhi Zhu, Zhizhong Liu, Jiayi Zhou, Hanwei Chen, Chuqiao Xiao, Xiang-Guang Li

“…Further analysis revealed that the up-regulated DEGs were enriched in tumor necrosis factor, nuclear factor kappa-B, mitogen-activated protein kinases, and Janus kinase/signal transducer and activator of transcription-related signaling pathways. …”
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TC2N maintains stem cell-like characteristics to accelerate lung carcinogenesis by blockade of dual specificity protein phosphatase 3 by Jing Gu, Yang-fan Lv, Ji-ying Xia, Fu-hai Bai, Ji Gong, Guang-qiang Pan, Bo Liu, Lu Huang, Qiao-nan Guo, Xiang-lin Hao

“…In previous studies, we have uncovered the oncogenic role and mechanisms of TC2N in lung cancer: TC2N achieves this by inhibiting the p53 signaling pathway and activating the NF-kappaB signaling pathway. Beyond that, its precise function in tumorigenesis is not fully understood. …”
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Synergy of Remote Sensing and Geospatial Technologies to Advance Sustainable Development Goals for Future Coastal Urbanization and Environmental Challenges in a Riverine Megacity by Minza Mumtaz, Syed Humayoun Jahanzaib, Waqar Hussain, Sadia Khan, Youssef M. Youssef, Saleh Qaysi, Abdalla Abdelnabi, Nassir Alarifi, Mahmoud E. Abd-Elmaboud

“…The framework integrates LULC analysis with SDG metrics, achieving an overall accuracy greater than 97%, with user and producer accuracies above 77% and a Kappa coefficient approaching 1, demonstrating a high level of agreement. …”
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Hyperbaric oxygen potentiates platelet-rich plasma composition and accelerates bone healing by Wen-Shuo Chang, Chien-Cheng Huang, Tzu-Hao Chen, Ssu-Han Chao, Cheng-Hsien Lin, Ching-Ping Chang, Chi-Sheng Chien

“…Bone healing was assessed weekly by X-ray, while histological and immunofluorescence analyses evaluated inflammatory status, osteoprotegerin (OPG), receptor activator of nuclear factor kappa-B ligand (RANKL) expression, and the presence of osteoblasts, osteoclasts, and osteocytes during healing. …”
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Mechanisms of wogonoside in the treatment of atherosclerosis based on network pharmacology, molecular docking, and experimental validation by Zhaohui Gong, Haixin Yang, Li Gao, Yi Liu, Qingmin Chu, Chuanjin Luo, Liang Kang, Huiqi Zhai, Qiang Xu, Wei Wu, Nan Li, Rong Li

“…Results Predictions were obtained that wogonoside treatment of atherosclerosis has 31 core targets, which are mainly focused on pathways such as Toll-like receptor (TLR) signaling pathway and NF-kappa B (NF-κB ) signaling pathway. Molecular docking and molecular dynamics simulations showed that wogonoside has good binding properties to the core targets. …”
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Implementation of prehospital point-of-care ultrasound using a novel continuous feedback approach in a UK helicopter emergency medical service by Salman Naeem, Shadman Aziz, Thomas Hirst, Johannes Strobel, Jamin M. Mulvey, Ailidh Lang, Jankee Patel, Alexander Smith, Ka Jun Cheng, Michael Palmer, Jonas Schlautmann, Michael D. Christian, Daniel Nevin

“…In-hospital diagnosis was sought for patients having the full Pump, Pleura and Pouring blood (PPPB) protocol. Cohen’s Kappa (ƙ) was calculated for inter-rater reliability. …”
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Validade Preliminar da Escala Perfil do Estilo de Vida Individual para uso online em tempos de distanciamento social by Sueyla Ferreira da Silva dos Santos, Thiago Ferreira de Sousa, Silvio Aparecido Fonseca, Mauro Virgílio Gomes de Barros, Gildeene Silva Farias, Markus Vinicius Nahas

“…A reprodutibilidade foi estimada via coeficiente Kappa. O nível de significância adotado foi de 5%. …”
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Lignans are the main active components of Schisandrae Chinensis Fructus for liver disease treatment: a review by Ke Fu, Shu Dai, Cheng Ma, Yafang Zhang, Shenglin Zhang, Cheng Wang, Lihong Gong, Honglin Zhou, Yunxia Li

“…The mechanism mainly involved adenosine 5’-monophosphate-activated protein kinase, endoplasmic reticulum stress, sterol regulatory element binding protein 1c, autophagy, transforming growth factor-β, mitogen-activated protein kinase, microRNA, nuclear factor kappa-B, nuclear factor erythroid-2-related factor 2, heat shock proteins and pregnane X receptor signaling pathways. …”
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Combination of Metformin and Magnesium Citrate Reduces TNF-α, NF-κB p65, IL-6, CD4, and MMP-9 Expressions in Diabetic Model Rats by Rachmi Fauziah Rahayu, Adi Prayitno, Bambang Purwanto, Widiastuti Soewondo, Ida Nurwati, Eti Poncorini Pamungkasari, Paramasari Dirgahayu

“…BACKGROUND: Diabetes, which causes various complications, involves pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), nuclear factor kappa B p65 (NF-κB p65), interleukin-6 (IL-6), cluster of differentiation 4 (CD4), and matrix metalloproteinase-9 (MMP-9). …”
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Attention to Monkeypox: An Interpretable Monkeypox Detection Technique Using Attention Mechanism by Avi Deb Raha, Mrityunjoy Gain, Rameswar Debnath, Apurba Adhikary, Yu Qiao, Md. Mehedi Hassan, Anupam Kumar Bairagi, Sheikh Mohammed Shariful Islam

“…Finally, to comprehensively assess the performance of our model, we employed a range of evaluation metrics, including Cohen&#x2019;s Kappa, Matthews Correlation Coefficient, and Youden&#x2019;s J Index, alongside traditional measures like accuracy, F1-score, precision, recall, sensitivity, and specificity. …”
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Identification of dominant species of submerged vegetation based on Sentinel-2 red-edge band: A case study of Lake Erhai, China by Xiaohan Wang, Yu Zhang, Yanhong Yu, Yunmei Li, Heng Lyu, Junda Li, Xiaolan Cai, Xianzhang Dong, Gaolun Wang, Jianzhong Li, Mengmeng Song, Lanlan Chen

“…The ensuing species identification exhibited a commendable overall accuracy rate of 96.8%, underscored by a Kappa coefficient of 0.95. Geospatial distribution revealed the prevalence of P. maackianus in the northern lake bay, counterbalanced by the dominance of V. natans in the southern lake bay. …”
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Classification performance and reproducibility of GPT-4 omni for information extraction from veterinary electronic health records by Judit M. Wulcan, Kevin L. Jacques, Mary Ann Lee, Samantha L. Kovacs, Nicole Dausend, Lauren E. Prince, Jonatan Wulcan, Sina Marsilio, Stefan M. Keller

“…GPT-4o demonstrated greater reproducibility than human pairs, with an average Cohen's kappa of 0.98 (IQR 0.98–0.99) compared to 0.80 (IQR 0.78–0.81) with humans. …”
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Comparación entre el Índice de Precipitación Estandarizado (SPI) y el Índice de Evapotranspiración Estandarizado (SPEI) para la sequía agrícola en el valle del Mantaro, Perú... by Víctor Antonio Ángeles Clemente, Del Piero R. Arana-Ruedas, Steve Dann Camargo Hinostroza, Oketta Onafuje

“…Además, el SPEI fue capaz de identificar eventos de sequía mayores en un +-3% para todas las estaciones meteorológicas y aplicando el análisis estadístico Kappa de Cohen, se puede evidenciar una concordancia sustancial pero no perfecta con un valor de no concordancia de +-40%. …”
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Application and comparison of five risk assessment methods in ferrous metal foundry enterprises with silica dust concentration exceeding the limit posts by Qimeng Li, Xiaoying Li, Ge Qin, Yuanmeng Qi, Jie Liu, Xiaocui Tang, Di Wu, Changfu Hao, Sihua Wang

“…The results obtained from the synthesis index method showed relatively lower levels, except for the index method, there was a certain correlation (r: 0.541–0.798, P &lt; 0.05) and consistency (kapa: 0.521–0.561, P &lt; 0.05) with the remaining four methods.ConclusionThis study shows that although there are some differences in the results of different OHRA methods, there is also some correlation between them, which can corroborate each other and enhance the reliability of the assessment results. …”
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Ginseng exhibits adaptogenic-like activity in mice exposed to hypoxic-anoxic stress through activation of antioxidant/BDNF protective mechanisms and inhibition of pro-inflammatory... by James Olukayode Oni, Divine Oluwaferanmi Oyenekan, Yetunde Olamide Olayemi, Osarugue Christabel Irabor, Precious Ogbuji, McCarthy Oritseweyinmi Tova, Paul Ademola Adeleke, Gbemisayo Adetomiwa Abbas, Solomon Umukoro

“…Blood glucose and corticosterone levels alongside brain contents of malondialdehyde, nitrites, antioxidant profiles, pro-inflammatory cytokines (tumor necrosis factor–alpha and interleukin-6), glutamate, brain derived neurotrophic factor (BDNF), and nuclear factor kappa B (NF-κB) were determined. …”
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