Prevalence and incidence of sarcopenia in Swiss postmenopausal women: findings from the OsteoLaus Cohort by Colin Vendrami, Elena Gonzalez Rodriguez, Guillaume Gatineau, Peter Vollenweider, Pedro Marques-Vidal, Olivier Lamy, Didier Hans, Enisa Shevroja

“…Agreement between definitions was predominantly “none” or “minimal” according to the Cohen Kappa score. CONCLUSION: This population-based cohort of postmenopausal women highlights an increase in sarcopenia prevalence and incidence beginning in the seventh decade of life, underscoring the accelerated decline in muscle health with age. …”
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Design, Content and Ecological Validity and Reliability of the Physical Activity and Sport Habits Questionnaire for Children Aged 8–12 Years in the Province of Gipuzkoa (Spain) by Aduna Badiola-Lekue, Irantzu Ibañez, Maite Fuentes, Javier Yanci, Oidui Usabiaga, Aitor Iturricastillo

“…Statistical analyses included the Wilcoxon test to compare expert ratings, effect size and percentage change calculations for magnitude assessment, and McNemar, McN-Bowker or Wilcoxon tests to compare differences between initial and repeat responses. Cohen’s Kappa was used to assess agreement. <b>Results:</b> The initial battery of items, submitted to the validation process, comprised 31 items across 10 dimensions, derived from validated questionnaires and published works. …”
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Influencia de actividades agropecuarias sobre la deforestación en la Zona Norte del Paraguay by Antonio Anibal Benítez Cañiza, Alicia Raquel Eisenkölbl Closs

“…La clasificación del uso de la tierra en áreas deforestadas se realizó mediante técnicas de teledetección, utilizando imágenes de los satélites Landsat 5 TM y Landsat 8 OLI, y se complementó con el análisis geoestadístico índice Kappa. El período de estudio abarco desde 2005 hasta 2018, y las variables analizadas incluyeron a la soja como por ejemplo el principal rubro de agricultura empresarial, actividad ganadera y la agricultura familiar campesina (AFC) en áreas deforestadas. …”
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Mechanism of Threshold Voltage Instability in Double Gate &#x03B1;-IGZO Nanosheet TFT Under Bias and Temperature Stress by Muhammad Aslam, Shu-Wei Chang, Yi-Ho Chen, Yao-Jen Lee, Yiming Li, Wen-Hsi Lee

“…Given the demand for CMOS-compatible, ultra-scaled, reliable, and high-performing devices, we fabricate and analyze scaled-channel a-IGZO-TFTs with an optimal double-gate structure, a thin nanosheet-based channel, and an effective high- <inline-formula> <tex-math notation="LaTeX">$\kappa$ </tex-math></inline-formula> dielectric namely HfO2. …”
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A proposal of visual assessment of serotonergic deficits in parkinsonian syndromes: An 123I-FP-CIT SPECT study by Tomoko Totsune, Toru Baba, Yoko Sugimura, Hideki Oizumi, Hiroyasu Tanaka, Toshiaki Takahashi, Masaru Yoshioka, Ken-ichi Nagamatsu, Atsushi Takeda

“…Results: The interrater agreement of the visual grading of 123I-FP-CIT uptake among the three raters was moderate (Fleiss’ Kappa 0.480 for midbrain, 0.488 for pons). The patterns of 123I-FP-CIT uptake in the pons differed significantly between patients with PD and PS (p = 0.035). …”
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Associations between contextual and compositional characteristics of early childcare facilities with health, health behaviours and well-being among young children aged 0 to 6 years... by Jennifer Hilger-Kolb, Sven Schneider, Raphael Herr, Nina Osenbruegge, Stephanie Hoffmann, Max Herke, Claudia Pischke, Leonie Sundmacher, Katharina Diehl

“…To determine inter-rater agreement between reviewers, we will calculate Cohen’s Kappa after both steps. Key characteristics (eg, country of origin, sample size, study design) of included articles will be extracted. …”
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Immunologic and inflammatory consequences of SARS-CoV-2 infection and its implications in renal disease by Hiam Naiditch, Michael R. Betts, H. Benjamin Larman, Moshe Levi, Avi Z. Rosenberg

“…Cytokines such as interleukin-1 (IL-1), IL-6, IL-12, and tumor necrosis factor α (TNFα), some of which may be produced through mechanisms involving nuclear factor kappa B (NF-κB), likely contribute to the hyperinflammatory state in patients with severe COVID-19. …”
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The diagnostic value and efficacy evaluation of lung ultrasound score in neonatal respiratory distress syndrome: a prospective observational study by Jian Dong, Yuhong Deng, Jin Tong, Tingting Du, Wenguang Liu, Yan Guo

“…Lung ultrasound was conducted and recorded at the 24th hour, the 48th hour, the 72nd hour, and the 7th day after drug administration. ROC curve analysis, Kappa statistics, and ANOVA were utilized to identify the optimal cut-off values for the lung ultrasound scores in diagnosing neonatal respiratory distress syndrome.Results89 neonates were diagnosed with respiratory distress syndrome, of whom 64 received surfactant replacement therapy. …”
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Guttiferone K Exerts the Anti-inflammatory Effect on Mycobacterium Tuberculosis- (H37Ra-) Infected Macrophages by Targeting the TLR/IRAK-1 Mediated Akt and NF-κB Pathway by Qingwen Zhang, Jinxia Sun, Yan Fu, Weigang He, Yinhong Li, Hongsheng Tan, Hongxi Xu, Xin Jiang

“…Further studies with immunoblotting and immunofluorescence revealed that Guttiferone K obviously inhibits the nuclear factor-kappa B (NF-κB) both in RAW264.7 and primary peritoneal macrophages relying on the TLR/IRAK-1 pathway. …”
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Protocol for Rhapsody: a longitudinal observational study examining the feasibility of speech phenotyping for remote assessment of neurodegenerative and psychiatric disorders by Allan H Young, Rebecca Strawbridge, Ammar Al-Chalabi, Dag Aarsland, Aleksandra Podlewska, Ray Chaudhuri, Elliot Hampsey, Marton Meszaros, Caroline Skirrow, Rosie H Taylor, Lazarus Chok, Jack Weston, Emil Fristed, Olabisi Awogbemila

“…Additionally, the study evaluates if acoustic and linguistic patterns can predict diagnostic group, as measured by the sensitivity, specificity, Cohen’s kappa and area under the receiver operating characteristic curve of the binary classifiers distinguishing each diagnostic group from each other. …”
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Prevalensi dan Tingkat Resistansi Silang Golongan Kuinolon Pada Escherichia coli Asal Usap Kloaka Ayam Layer by Nur Nur Hidayah, Maria Fatima Palupi, Novida Ariyani Ariyani, Indryana Indryana Indryana, Anna Miftahul Jannah, Siti Komariyah Komariyah, Rosana Anita Sari, Ambarwati Ambarwati Ambarwati, Emi Rusmiati Rusmiati, Nafisah Idrishanty Idrishanty, Fika Asti Fanani

“…Tingkatresistansi silang kuinolon dievaluasi dengan statistik kappa (k) berdasarkan resistansi siprofloksasin terhadap norfloksasin, enrofloksasin, flumekuin, dan marbofloksasin. …”
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Middle Cerebral Artery Pulsatility Index for Prediction of Successful Induction of Labour in Postdated Pregnancy: A Prospective Observational Study by Yashi Nagar, Rekha Bharti, Kajal Baleja, Amita Malik, Divya Pandey, Jyotsna Suri

“…MCA PI had almost perfect reliability for predicting the outcome of labour induction, Kappa=0.91 and Youden index score of 99.3. Conclusion: MCA PI is a good predictor of successful labour induction in nulliparous women with postdated pregnancy.…”
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Wetland degradation monitoring using multi-temporal remote sensing data and watershed land degradation index by I. Ridwan, S. Kadir, N. Nurlina

“…This index integrates land use land cover, vegetation coverage, soil erosion, and soil moisture content.FINDINGS: The proposed comprehensive land degradation index in this study demonstrated that (a) the land degradation index, which successfully monitored the spatio-temporal aspect of land degradation (kappa coefficient > 0.73 and overall accuracy > 86 percent), is regarded as having high accuracy. …”
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RNA m6A involves in regulation of oxidative stress and apoptosis may via NF-kB pathway in cadmium-induced lung cells by Nan Zhang, Jie Yang, Yuan Zhao, Wenhong Li, Bo Zhao, Rongxian Li, Zuoshun He, Shiyan Gu

“…Moreover, the mRNAs of Nuclear factor kappa B (NF-κB) p65 and NAD(P)H: quinone oxidoreductase 1 (NQO1), the key signaling molecules in these two signaling pathways, were predicted to contain m6A modification sites with high confidence. …”
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Ursodeoxycholic acid protects against sepsis-induced acute kidney injury by activating Nrf2/HO-1 and inhibiting NF-κB pathway by Yunpeng Lou, Hongguang Shi, Ning Sha, Feifei Li, Xiaofeng Gu, Huiyan Lin

“…Oxidative stress parameters and nuclear factor erythroid 2-related factor 2 (Nrf2)/ heme oxygenase-1 (HO-1) pathway, pro-inflammatory cytokines and nuclear factor-kappa B (NF-κB) pathway were also evaluated. Additionally, HK-2 cells were treated with LPS in vitro, and cell viability and apoptosis were detected using CCK-8 kit and flow cytometer, respectively. …”
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Targeting and editing the second exon of bmp6 gene results in a silver carp with reduced intramuscular bones by Shuang Niu, Xiaohui Li, Cui Feng, Zewen Zhang, Hang Sha, Xiangzhong Luo, Guiwei Zou, Hongwei Liang

“…DEGs identified only in CH-E2 group were significant enrichment in “osteoclast differentiation”, “NF-kappa B signaling pathway” and “cytokine-cytokine receptor interactions”, indicating a specificity unique to CH-E2 group. …”
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Study of a Deep Learning Reconstruction Algorithm for Displaying Small- and Medium-sized Blood Vessels in Upper Abdominal Energy Spectrum CT by Qin WANG, Weijie YAN, Yuan YUAN, Hehan TANG, Liping DENG

“…Differences in SNR, CNR, and background noise among the four groups of images were compared using one-way analysis of variance (ANOVA) and paired t-tests. The kappa test was used to compare differences in the consistency of the subjective evaluations. …”
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Polydatin retards the progression of osteoarthritis by maintaining bone metabolicbalance and inhibiting macrophage polarization by Qi Sun, Xin-Yu Nan, Hui Wang, Shuo Pan, Gang Ji, Ya-Feng Guo, Ya-Heng Zhao, Gao-Cen Li, Shao-Shi Guo, Lu-Feng Lin, Yu-Jie Jin, Xue Li Zhang, Chang-Cheng Liu, Guo-Bin Liu

“…MicroCT analysis was conducted to assess changes in the microstructure of subchondral bone trabeculae, and Western blot was performed to measure the expression of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway and markers of M1 polarization in macrophages.ResultsPD significantly delays the progression of osteoarthritis induced by ACLT, effectively inhibits IL-1β-induced joint inflammation, bone metabolic remodeling and extracellular matrix degradation. …”
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Analytical and clinical validation of a novel MeltPlus TB-NTM/RIF platform for simultaneous detection of Mycobacterium tuberculosis complex, Non-Tuberculous Mycobacteria and rifamp... by Zhuo Wang, Yuanwu Zou, Zihan Wei, Guanghong Bai, Xiaolin Wang, Shaoyi Qu, Jie Shi, Yaping Jiang, Cuijiao Gu

“…RIF resistance detection showed a sensitivity of 90.24% (95% CI:76.87-97.28%) and specificity of 95.98% (95% CI: 91.89-98.37%), with a high level of diagnostic agreement (Kappa: 0.8338) compared to GeneXpert. Sanger sequencing revealed that novel assay correctly classifies 98.6% of study cases as RIF resistant or susceptible, slightly higher that of GeneXpert.DiscussionThese findings indicate that the novel MeltPlus MTB-NTM/RIF platform provides a rapid and accurate method for the simultaneously detecting MTBC, NTM, and RIF resistance, making it a promising tool for clinical TB/NTM diagnosis and management, further multi-center and field studies are recommended to validate its broader applicability.…”
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Spatiotemporal analysis of oil palm land clearing by M.K. Rosyidy, E. Frimawaty

“…Accuracy assessment of classification results uses a confusion matrix taking into account overall accuracy and Kappa Hat. Within the field observation, the validation class is the oil palm class, using documentation and plotting using the global positioning system, and other classes are validated using the Region of Interest collected through Google Earth. …”
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