Reliability of the Second and Third Iterations of the Sensory–Motor Dysfunction Questionnaire in a Subclinical Neck Pain Population by Ushani Ambalavanar, Heidi Haavik, Nitika Kumari, Imran Amjad, Nooshin Khobzi Rotondi, Bernadette Ann Murphy

“…Reliability statistics (quadratic weighted kappa (K_w) and Cronbach’s alpha (α)) were calculated for all items (V2) and total scores (V2 and V3). …”
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Pituitary Adenylate Cyclase-Activating Polypeptide Protects Glomerular Podocytes from Inflammatory Injuries by Kenichi Sakamoto, Kyoko Kuno, Minoru Takemoto, Peng He, Takahiro Ishikawa, Shunichiro Onishi, Ryoichi Ishibashi, Emiko Okabe, Mayumi Shoji, Akiko Hattori, Masaya Yamaga, Kazuki Kobayashi, Harukiyo Kawamura, Hirotake Tokuyama, Yoshiro Maezawa, Koutaro Yokote

“…PACAP also had downregulated the expression of MCP-1 through the protein kinase A signaling pathway; this led to the attenuation of the activation of extracellular signal-regulated kinase and nuclear factor-kappa B signaling. Our results suggested that PACAP could be a possible treatment option for DN through the use of anti-inflammation effects on glomerular podocytes.…”
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GV1001, hTERT Peptide Fragment, Prevents Doxorubicin-Induced Endothelial-to-Mesenchymal Transition in Human Endothelial Cells and Atherosclerosis in Mice by Wei Chen, Seojin Kim, Sharon Y. Kim, Cheyenne Beheshtian, Naryung Kim, Ki-Hyuk Shin, Reuben H. Kim, Sangjae Kim, No-Hee Park

“…By mitigating mitochondrial damage, GV1001 reduced the accumulation of mitochondrial and cellular reactive oxygen species (ROS), repressed the activation of nuclear factor kappa B (NF-κB), and reduced the production of proinflammatory cytokines in endothelial cells. …”
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Cross-cultural adaptation and validation of the Spanish version of the Prevent for Work questionnaire by Julia Blasco-Abadía, Pablo Bellosta-López, Víctor Doménech-García, Thorvaldur Skuli Palsson, Steffan Wittrup McPhee Christensen, Steffan Wittrup McPhee Christensen, Morten Hoegh, Pedro Berjano, Francesco Langella

“…Furthermore, the P4Wq showed good to excellent item response stability (weighted kappa = 0.75–0.96) and good for the total score (ICC = 0.98).ConclusionThe Spanish version of the P4Wq was face-valid and exhibited a similar structure as the original version. …”
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A Large-Scale Agricultural Land Classification Method Based on Synergistic Integration of Time Series Red-Edge Vegetation Index and Phenological Features by Huansan Zhao, Chunyan Chang, Zhuoran Wang, Gengxing Zhao

“…The study yielded three significant findings: (1) The synergistic application of NDRE₇₀₅ and PSRI significantly outperformed single-index approaches, demonstrating the effectiveness of our dual-index strategy; (2) The integration of SFPs and PFPs with time series REVI markedly enhanced feature discrimination at crucial growth stages, with PFPs showing superior capability in distinguishing agricultural land types through amplified phenological signatures; (3) Our optimal classification scheme (FC6), leveraging both enhanced spatial and phenological features, achieved remarkable accuracy (93.21%) with a Kappa coefficient of 0.9159, representing improvements of 4.83% and 0.0538, respectively, over the baseline approach. …”
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AI-Driven Plant Health Assessment: A Comparative Analysis of Inception V3, ResNet-50 and ViT with SHAP for Accurate Disease Identification in Taro by Valeria Maeda-Gutiérrez, Juan José Oropeza-Valdez, Luis C. Reveles-Gómez, Cristian Padron-Manrique, Osbaldo Resendis-Antonio, Luis Octavio Solís-Sánchez, Hector A. Guerrero-Osuna, Carlos Alberto Olvera Olvera

“…The model’s efficacy was evaluated through multi-class statistical metrics, including accuracy, precision, F1 score, recall, specificity, Chohen’s kappa, and area under the curve. Among the architectures, Inception V3 exhibited superior performance in accuracy (0.9985), F1 score (0.9985), recall (0.9985), and specificity (0.9992). …”
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Protective Effects of Baicalein on Lipopolysaccharide-Induced AR42J PACs through Attenuation of Both Inflammation and Pyroptosis via Downregulation of miR-224-5p/PARP1 by Ming-Wei Liu, Chun-Hai Zhang, Shou-Hong Ma, De-Qiong Zhang, Li-Qiong Jiang, Yang Tan

“…The RNA and protein expression of miR-224-5p, poly ADP-ribose polymerase-1 (PARP1), nuclear transcription factor-κB65 (NF-κB65), phospho-kappa B alpha(p-IκB-α), interleukin(IL)-18R, NOD-like receptor thermal protein domain-associated protein 3 (NLRP3), gasdermin D (GSDMD), apoptosis-associated speck-like protein containing a CARD (ASC), and caspase-1 was detected based on the WB and RT-PCR assays. …”
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NF-κB-Specific Suppression in Cardiomyocytes Unveils Aging-Associated Responses in Cardiac Tissue by Letícia Aparecida Lopes Morgado, Larissa Maria Zacarias Rodrigues, Daiane Cristina Floriano Silva, Bruno Durante da Silva, Maria Claudia Costa Irigoyen, Ana Paula Cremasco Takano

“…Cellular mechanisms such as senescence, telomere shortening, and DNA damage contribute to these processes. Nuclear factor kappa B (NF-κB) has been implicated in mediating cellular responses in aging tissues, and increased NF-κB expression has been observed in the hearts of aging rodents. …”
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Comparação entre os Critérios GLIM, o Consenso de Caquexia do Câncer e a ASG-PPP VR para o Diagnóstico Nutricional de Pacientes com Câncer Avançado em Cuidados Paliativos by Emanuelly Varea Maria Wiegert, Gabriella da Costa Cunha, Larissa Calixto-Lima

“…Foram analisados os valores de concordância pelo coeficiente de Kappa (k) e calculadas as medidas de acurácia entre os métodos. …”
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Curcumin and α/β-Adrenergic Antagonists Cotreatment Reverse Liver Cirrhosis in Hamsters: Participation of Nrf-2 and NF-κB by José Roberto Macías-Pérez, Bruno Jesús Vázquez-López, Martin Humberto Muñoz-Ortega, Liseth Rubí Aldaba-Muruato, Sandra Luz Martínez-Hernández, Esperanza Sánchez-Alemán, Javier Ventura-Juárez

“…In addition, liver fibrosis may be associated with a decrease of the antioxidant response of the nuclear factor erythroid 2-related factor 2 (Nrf-2) and the overregulation of the proinflammatory pathway of nuclear factor kappa B (NF-κB). Therefore, in the present work, the capacity of doxazosin (α1 antagonist), carvedilol (nonselective beta-adrenoceptor blocker with alpha 1-blocking properties), and curcumin (antioxidant and anti-inflammatory compound) to reverse liver cirrhosis and studying the possible modulation of Nrf-2 and NF-κB were evaluated. …”
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Evaluación del rol del equipo de coordinación de nefrología en la consulta externa específica de acceso vascular. ¿Qué podemos aportar de nuevo? by Néstor Fontseré, Gaspar Mestres, Xavi Yugueros, Daniel Gil, Carla Blanco, Valentín Lozano, Lidia María Rodas, Arantxa Gelabert, Paula Escarcena, Rosa Ramos, Francisco Maduell

“…Of the total number of procedures, nephrology obtained an adequate degree of agreement in 93.6% of the cases (kappa index: 0.886). The preoperative factors associated with greater discrepancies in assessments were age (P=.022) and arterial diameter (P =.032). …”
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İlk trimester doppler ultrasonografinin kromozomal anomaliler ve gebelik prognozunu tahmin etmedeki etkinliği by Aykut Barut, Görker Sel, Özgür Volkan Akbulut

“…Amaç: 11-13+6 gebelik haftalarında yapılan Doppler ultrasonografik muayene bulgularının, fetal kromozomal anomaliler, gebelik-doğum prognozu ve yeni doğan yoğun bakım ihtiyacını tahmin etmedeki etkinliğinin araştırılması.Gereç ve Yöntem: Çalışma Mart 2005 -Mart 2006 tarihleri arasında, BEÜ Kadın Doğum gebe polikliniğine başvuran sağlıklı gebeler ile yapılmıştır. 11-13+6 haftalık, fetal kalp aktivitesi pozitif, tekil gebeliği mevcut olan 130 gebe çalışmaya alınmıştır. …”
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The Effect of Innovative Technology Benefits and E-Commerce Using Motivations on Customer Experience and Customer Information by Zahra Bigdelou, Alireza Rousta, Farzad Asayesh

“…The statistical population of the study was all customers of Digi Kala Co. Due to the uncertainty of these customers, based on Cochran's formula at a level of 5% error, 384 people were selected as a sample. …”
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Gazzâlî’nin İhyâ’sında Hz. Ali’nin Tasavvufa Kaynaklık Eden Sözleri Üzerine Bir Değerlendirme by Muhammed Veysel Akkaya

“…Fehmin öğrenmekle değil kalb ile keşfî olacağını belirtmiştir. Ayrıca fehmin hikmetle doğrudan ilişkisine değinmiştir. …”
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Okuma Üzerine Sanat Temelli Boylamsal Bir Araştırma: İlkokul Öğrencileri Okurken Nasıl Hissediyor? by Dilek Bilhan, Hülya Kartal

“…Araştırma bulgularına göre, öğrencilerin büyük çoğunluğu hem ikinci hem de dördüncü sınıftayken okurken olumlu duygular hissetmekte; ikinci sınıftayken öğrencilerin sadece altısı dördüncü sınıftayken ise on ikisi okurken “farklı duygular” hissetmekte; kız öğrenciler erkek öğrencilere göre hem ikinci hem de dördüncü sınıftayken duygularını ifade ederken “kalp” figürlerine daha fazla yer vermekte; hem kız hem de erkek öğrencilerin yaklaşık olarak yarısı hem ikinci sınıfta hem de dördüncü sınıfta okurken hissettiklerine yönelik duygu durumlarını ifade ederken çizimlerinde açık kitap figürlerine yer vermekte; düşünme ve konuşma baloncuğu figürlerine yer vermeleri bakımından sınıf düzeylerine göre farklılık bulunmakta ve öğrenciler okudukları veya okumak istedikleri eserlerin isimlerine hem ikinci hem de dördüncü sınıfta çizimlerinde yer vermektedir. …”
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IV. MURAT’I KONU ALAN İKİ OYUNDA SANAT - İKTİDAR ÇATIŞMASI by Sena Küçük

“…Murat 1988 ve Savaş Aykılıç Bir Kalem, Bir Kılıç, Bir de Kalp 2003 adlı oyunlarında bu konuyu ele almışlardır.Makale, bu oyunların incelenerek, aynı tarihî konunun sanat eserlerinde aldığı farklı biçimleri, sanatın sınırsızlığını, tarihin tiyatroya geniş imkânlar sunduğunu vurgulamayı, iki eserin kesişen ve ayrışan yönlerini ortaya koymayı amaçlamaktadır. …”
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Investigation of the Mechanism Underlying Calcium Dobesilate-Mediated Improvement of Endothelial Dysfunction and Inflammation Caused by High Glucose by Yijun Zhou, Chaojun Qi, Shu Li, Xinghua Shao, Zhaohui Ni

“…Western blot and real-time PCR analyses were used to detect PTX3, p-IKBa/IKBa (I-kappa-B-alpha), and p-eNOS/eNOS (endothelial nitric oxide synthase) expression in mice and HUVECs. …”
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良恶性病变食管组织及其邻近组织中HOXA5 蛋白 和mRNA的表达

“…④HOXA5 蛋白表达与其mRNA的表达一致性程度良好(Kappa = 0.718, P < 0.05)。【结论】 HOXA5 蛋白和mRNA的表达在癌旁不典型增生组织、食管鳞癌组织中明显升高,它可能是食管鳞癌发生过程中的早期事件。…”
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Curva de aprendizaje de la ecografía renal en una unidad docente pluriprofesional by Laura Redón-Gálvez, Nuria Juárez-Ruperto, Carlos E. León-Solano, Marcos Luján-Galán, Álvaro Páez-Borda

“…Resultados: El coeficiente kappa de concordancia entre el experto y los estudiantes fue bueno (&ge; 0,67) en el 58,3% de los casos. …”
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Dietary Chitosan Supplementation Increases Microbial Diversity and Attenuates the Severity of Citrobacter rodentium Infection in Mice by Guiping Guan, Hongbing Wang, Shuai Chen, Gang Liu, Xia Xiong, Bie Tan, Veeramuthu Duraipandiyan, Naif Abdullah Al-Dhabi, Jun Fang

“…Furthermore, mice in COS group were also found to experience inhibited activation of nuclear factor-kappa B (NF-κB) in the colonic tissue. Overall, the findings revealed that adding 300 mg/kg COS to the diet changed the composition of the intestinal microflora of mice, resulting in suppressed NF-κB activation and less production of TNF-α and IL-6; and these changes led to better control of inflammation and resolution of infection with C. rodentium.…”
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