Clasificación supervisada, evaluación multicriterio y modelos de localización-asignación para instalaciones de destilación de aceite esencial de Cistus ladanifer by Carlos Pérez-Izquierdo, Fernando Pulido

“…Los clasificadores Máxima Probabilidad, máquinas de vector soporte y redes neuronales lograron precisiones de clasificación superiores al 90 % en fiabilidad global y coeficiente Kappa. La superficie total de jaras potencialmente explotable obtenida en la clasificación fue de 20 889 ha, de las cuales 15 241 ha (72,96 %) eran viables para la recolección. …”
Get full text

HDST 技术应用于卵巢癌新辅助化疗中的效果分析 by 饶群仙, 韦苑, 林少丹, 彭永排, 林荣春, 何远桥, 林仲秋, 陈青松

“…HDST    结果与临床疗效间一致性较好（Kappa=1.000，P<0.05），灵敏度、特异度和正确指数为100%；患者Fagotti 评分变化和HDST 有效率间存在显著正相关（rs=0.678，P<0.05），而CA125、HE4 总下降率和HDST 有效率间无相关（P>0.05）。…”
Get full text

Staging of Primary Abdominal Lymphomas: Comparison of Whole-Body MRI with Diffusion-Weighted Imaging and 18F-FDG-PET/CT by Alessandro Stecco, Francesco Buemi, Martina Quagliozzi, Mariangela Lombardi, Alberto Santagostino, Gian Mauro Sacchetti, Alessandro Carriero

“…There were no statistically significant differences between the two techniques p=0.05. The weighted kappa agreement statistics with a 95% confidence interval were 0.97 (0.95–0.99) between the two MRI readers and 0.87 (0.82–0.92) between the two methods. …”
Get full text

Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis by Wenchang Yang, Yaxin Wang, Peng Zhang, Tao Wang, Chengguo Li, Xin Tong, Xiangyu Zeng, Yuping Yin, Kaixiong Tao, Ruidong Li

“…In addition, OI inhibited Con A-induced activation of nuclear factor-kappa B (NF-𝜅B) and the expression of proinflammatory cytokines in macrophages. …”
Get full text

Neuroprotective Role of Transchalcone in Parkinson‘s Disease through AMP-activated Protein Kinase-mediated Signaling Pathway by Yao Cheng, Shaik Althaf Hussain, Turki Mayudh Alrubie, Xiaomin Zhang

“…Striatal dopamine and cytokines (interleukin 1-beta [IL-1 β], IL-10) and p65-nuclear factor kappa-B (NF-κB) levels were measured with enzyme-linked immunosorbent assay. …”
Get full text

Cardiovascular Risk Assessment: A Comparison of the Framingham, PROCAM, and DAD Equations in HIV-Infected Persons by Max Weyler Nery, Celina Maria Turchi Martelli, Erika Aparecida Silveira, Clarissa Alencar de Sousa, Marianne de Oliveira Falco, Aline de Cássia Oliveira de Castro, Jorge Tannus Esper, Luis Carlos Silva e Souza, Marília Dalva Turchi

“…The agreement between the CVD risk equations was assessed using Cohen's kappa coefficient. The participants' mean age was 36.8 years (SD = 10.3), 76.9% were men, and 66.3% were on antiretroviral therapy. 47.8% of the participants had abdominal obesity, 23.1% were current smokers, 20.0% had hypertension, and 2.0% had diabetes. …”
Get full text

PD-L1 Immunohistochemistry Comparability and Their Correlation with Clinical Characteristics in NSCLC by Chiao-En Wu, Ching-Fu Chang, Liao Kou-Sheng, Ju Chiang, Shih-Wei Lee, Yu-Chi Chiu

“…The above findings were confirmed by Cohen’s kappa. In addition, we found that PD-L1 expression was significantly associated with advanced N stage but not with T and M stages. …”
Get full text

Initial use of supplementary oxygen for trauma patients: a systematic review by Trine Grodum Eskesen, Josefine Stokholm Baekgaard, Jacob Steinmetz, Lars S Rasmussen

“…Two independent reviewers screened and identified studies and extracted data from included studies.Results 6142 citations were screened with an inter-rater reliability (Cohen’s kappa) of 0.88. One interventional trial of intubated trauma patients was included. 68 trauma patients were randomised to receive an FiO2 of 0.80 (intervention group) or 0.50 (control group) during mechanical ventilation (first 6 hours). …”
Get full text

Kronik Hastalıkların Yol Açtığı Bazı Toplumsal Problemler by Oya Eryiğit Günler

“…Kronik hastalıkların uzun dönemli olmaları, kişilerin sosyal problemlere maruz kalma olasılığını artırabilmektedir. Sadece kronik hastalıklara sahip olan kişiler değil, onların yakın çevrelerinde bulunan kişiler de birtakım toplumsal sorunlar yaşayabilmektedirler. …”
Get full text

Near-infrared light reflection for the early detection of proximal caries in posterior teeth: an in vivo study by Liheng Shen, Xiqun Yang, Chengzhi Dong, Xiaodong Tang, Simin Zheng, Tingting Wang, Linhong Wang, Fan Yang, Yuchen Zheng

“…Results For posterior teeth, the accuracy of near-infrared light reflection was 0.78, with a sensitivity of 0.44 and a specificity of 0.83. Cohen’s kappa showed poor consistency between the two diagnostic methods, near-infrared light reflection and bitewing radiography. …”
Get full text

Fine-scale forest classification with multi-temporal sentinel-1/2 imagery using a temporal convolutional neural network by Rongfei Duan, Chunlin Huang, Peng Dou, Jinliang Hou, Ying Zhang, Juan Gu

“…Results show that TempCNN achieves the best performance (overall accuracy = 91.67%, Kappa = 0.895) and is particularly effective at handling complex data and mixed forests. …”
Get full text

Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice by Hongxing Zhang, Chi Shang, Zhao Tian, Hatem K. Amin, Rami B. Kassab, Ahmed E. Abdel Moneim, Yingang Zhang

“…Carrageenan injection potentiated an inflammatory reaction as presented by the elevated serological C-reactive protein (CRP) levels and transcription of tumor necrosis factor-alpha (TNF-α, Tnfα), interleukin-1 beta (IL-1β, Il1b), interleukin-2 (IL-2, Il2), inducible nitric oxide synthase (iNOS), nitric oxide (NO), cyclooxygenase-2 (COX-2, Ptgs2), prostaglandin E2 (PGE2), monocyte chemoattractant protein-1 (MCP-1, Ccl1), nuclear factor kappa B (NF-κB), and myeloperoxidase (MPO) activity, while interleukin-10 (IL-10) was declined in the injured paw tissue. …”
Get full text

Forskolin Inhibits Lipopolysaccharide-Induced Modulation of MCP-1 and GPR120 in 3T3-L1 Adipocytes through an Inhibition of NFκB by Jeanne Durendale Chiadak, Tatjana Arsenijevic, Kevin Verstrepen, Françoise Gregoire, Nargis Bolaky, Valérie Delforge, Véronique Flamand, Jason Perret, Christine Delporte

“…The aim of this study was to determine the signaling pathway by which Forskolin (FK), a cyclic adenosine monophosphate- (cAMP-) promoting agent causing positive changes in body composition in overweight and obese adult men, affects MCP-1 and GPR120 expression during an inflammatory response induced by lipopolysaccharide (LPS) in adipocytes, such as in an obese state. 3T3-L1 cells differentiated into adipocytes (DC) were stimulated with LPS in the absence or presence of FK and inhibitors of TLR-4 and inhibitor of kappa B (IκBα). In DC, LPS increased MCP-1, TLR-4, and nuclear factor-κB1 (NFκB1) mRNA levels, whereas it decreased GPR120 mRNA levels. …”
Get full text

DualTransAttNet: A Hybrid Model with a Dual Attention Mechanism for Corn Seed Classification by Fei Pan, Dawei He, Pengjun Xiang, Mengdie Hu, Daizhuang Yang, Fang Huang, Changmeng Peng

“…Compared to typical machine learning and deep learning models, the proposed model exhibits superior performance with an overall accuracy, F1-score, and Kappa coefficient of 90.01%, 88.9%, and 88.4%, respectively. …”
Get full text

Identification and Validation of the Pyroptosis-Related Hub Gene Signature and the Associated Regulation Axis in Diabetic Keratopathy by Yi Cui, Li Wang, Wentao Liang, Li Huang, Shuting Zhuang, Hong Shi, Nuo Xu, Jianzhang Hu

“…Gene Set Enrichment Analysis highlighted significant enrichment of the NOD-like receptor, Toll-like receptor, and NF-kappa B signaling pathways. Intersection of DEGs and pyroptosis-related datasets showed 33 differentially expressed pyroptosis-related genes (DEPRGs) associated with pathways such as IL-17, NOD-like receptor, TNF, and Toll-like receptor signaling. …”
Get full text

Sequential testing with Xpert MTB/RIF assay for diagnosis of tuberculous meningitis in Maharaj Nakorn Chiang Mai University Hospital by Poramed Winichakoon, Kanokwan Watcharasaksilp, Sunisa Butphet, Kanlaya Wongworapat, Chansom Pantip, Phadungkiat Khamnoi, Khuanchai Supparatpinyo, Parichat Salee

“…Agreement between Xpert MTB/RIF and MGIT culture was 93.85% (p < 0.001), with a kappa score of 0.80 (95% CI 0.60–0.99). Sequential testing with a TBM score cut-off of 6, followed by Xpert MTB/RIF improved specificity from 96.23 to 97.15%. …”
Get full text

The Impact of (DEM) Accuracy and (LC/LU) Resolution on the Watersheds Areas by Alaa Qais Muttar, Mustafa Tariq Mustafa, Muntasir Abdl Hameed Abdl Shareef

“…The optimum most accurate image for (LC/LU) thematic map production in the selected area is (Sentinel-2 l0 m) satellite at overall Classification accuracy (97%) and the overall kappa statistics (95%). The optimum remote sensing data (sentinel-2 image and Copernicus DEM) are mapped, 3D simulated and analyzed by GIS to calculate the areas of (LC/LU) main layers and to find that the considerable part of the selected watersheds is the area of green lands 404.32676 km2 was about 54.396% of the total area in the study, and these areas are vary depending on many factors such as remote sensing data, precipitation, cultivation, season, and human activities. …”
Get full text

Sorbitol Destroyed Intestinal Microfold Cells (M Cells) Development through Inhibition of PDE4-Mediated RANKL Expression by Li Xiang, Wenxu Pan, Huan Chen, Wenjun Du, Shuping Xie, Xinhua Liang, Fangying Yang, Rongwei Niu, Canxin Huang, Minan Luo, Yuxin Xu, Lanlan Geng, Sitang Gong, Wanfu Xu, Junhong Zhao

“…Herein, in comparison to the mannitol group (control group), we found that intestinal M-cell development was inhibited in response to sorbitol treatment as evidenced by impaired enteroids accompanying with decreased early differentiation marker Annexin 5, Marcksl1, Spib, sox8, and mature M-cell marker glycoprotein 2 expression, which was attributed to downregulation of receptor activator of nuclear factor kappa-В ligand (RANKL) expression in vivo and in vitro. …”
Get full text

Correlation between axial and coronal common bile duct diameters in computed tomography: a retrospective study of 1064 patients by Adisak Kasemassawachanont, Natinee Chuangsuwanich, Wanicha Lertpipopmetha, Nutthanun Panrong, Kittipott Thusneyapan, Sasima Tongsai, Napakadol Noppakunsomboon, Rathachai Kaewlai

“…When a cutoff value of 7 mm was used to predict an abnormal axial diameter, the agreement between axial and coronal CBD diameters was substantial (Kappa = 0.715) with discordance between the two measurements identified in 6.2% of cases (66/1064) when a) coronal diameter < 7 mm but axial measurement  ≥ 7 mm (39/1064; 3.7%) and b) coronal diameter  ≥ 7 mm but axial measurement < 7 mm (27/1064; 2.5%). …”
Get full text

Decoding nature: multi-target anti-inflammatory mechanisms of natural products in the TLR4/NF-κB pathway by Yue Zhao, Yue Zhao, Jiacai Wu, Xiaolan Liu, Xiaolan Liu, Xu Chen, Xu Chen, Juan Wang, Juan Wang

“…Research has demonstrated that many natural products exert notable anti-inflammatory effects by modulating the Toll-like receptor 4 (TLR4) and nuclear factor kappa B (NF-κB) signaling pathways. The research on related signal transduction mechanisms and pharmacological mechanisms is increasingly being discovered and validated. …”
Get full text