Molecular Characterization of a Multidrug-Resistant Klebsiella pneumoniae Strain R46 Isolated from a Rabbit by Fei Wu, Yuanyuan Ying, Min Yin, Yi Jiang, Chongyang Wu, Changrui Qian, Qianqian Chen, Kai Shen, Cong Cheng, Licheng Zhu, Kewei Li, Teng Xu, Qiyu Bao, Junwan Lu

“…The whole genome encoded 34 antibiotic resistance genes including a newly identified chromosome-encoded florfenicol resistance gene named mdfA2. pR46-270, besides encoding 26 antibiotic resistance genes, carried four clusters of heavy metal resistance genes and several virulence-related genes or gene clusters. …”
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Diacylglycerol kinase δ is required for skeletal muscle development and regeneration by Hiromichi Sakai, Chiaki Murakami, Mayumi Takechi, Takeshi Urano, Fumio Sakane

“…Notably, skeletal muscle injury induced by a cardiotoxin highly up‐regulated DGKδ protein expression, and the DGKδ deficiency significantly reduced the thickness of myofibers, the expression levels of myogenic differentiation markers such as embryonic myosin heavy chain and myogenin, and the number of newly formed myofibers containing multiple central nuclei during muscle regeneration. …”
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Concentration and health risk assessment of toxic metals in giblets of free-range chickens in Lokoja, Nigeria by Jude Ehwevwerhere Emurotu, Tenimu Adogah Abubakar, Loveth Chukwu, Queen Ese Umudi, Victory Imokan Imumorin, Gloria D. Paul, Grace Unekwuojo Oboni

“…To monitor the quality of giblets consumed and to evaluate the risk to the public's health, this study aimed to determine the residual concentrations of heavy metals (Al, As, Cd, Cr, Mn, Ni, Pb and Zn) in the gizzard, kidney, and liver of free-range chickens. …”
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The Protective Role of HLA-DRB113 in Autoimmune Diseases by Andreia Bettencourt, Cláudia Carvalho, Bárbara Leal, Sandra Brás, Dina Lopes, Ana Martins da Silva, Ernestina Santos, Tiago Torres, Isabel Almeida, Fátima Farinha, Paulo Barbosa, António Marinho, Manuela Selores, João Correia, Carlos Vasconcelos, Paulo P. Costa, Berta Martins da Silva

“…We genotyped for HLA-DRB1 locus 1228 patients with AIDs-213 with Systemic Lupus Erythematosus (SLE), 166 with Psoriasis or Psoriatic Arthritis (Ps + PsA), 153 with Rheumatoid Arthritis (RA), 67 with Systemic Sclerosis (SSc), 536 with Multiple Sclerosis (MS), and 93 with Myasthenia Gravis (MG) and 282 unrelated controls. We confirmed previously established associations of HLA-DRB115 (OR = 2.17) and HLA-DRB103 (OR = 1.81) alleles with MS, HLA-DRB103 with SLE (OR = 2.49), HLA-DRB101 (OR = 1.79) and HLA-DRB104 (OR = 2.81) with RA, HLA-DRB107 with Ps + PsA (OR = 1.79), HLA-DRB101 (OR = 2.28) and HLA-DRB108 (OR = 3.01) with SSc, and HLA-DRB103 with MG (OR = 2.98). …”
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Exploring the potential of buckwheat hull-based biosorbents for efficient water pollutant removal by Maja Adamović, Marija Stjepanović, Natalija Velić

“…It highlights the use of both native (unmodified) and chemically or physically modified buckwheat hulls in adsorption processes to remove a range of waterborne pollutants, including heavy metals and synthetic dyes. Based on the existing body of literature, it is evident that buckwheat hulls, in their various forms, represent a sustainable and efficient alternative to conventional non-renewable adsorbents. …”
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Air Quality Assessment by Moss Biomonitoring and Trace Metals Atmospheric Deposition by Pranvera Lazo, Alda Kika, Flora Qarri, Lirim Bekteshi, Shaniko Allajbeu, Trajce Stafilov

“…Fe, Cd, Cu, Pb, and Zn were mostly higher between a few regions with few obvious anomalies positioned in the center of the country with high industrial activity, in the areas with heavy traffic, and in the cross-borders of Albania with Monte Negro and Greece mostly emerging from the local contribution of anthropogenic activities, local lithology, and transboundary pollution sources. …”
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Incidence and Mechanisms of Coronary Perforations during Rotational Atherectomy in Modern Practice by Yen-Hsiang Wang, Wei-Jhong Chen, Yu-Wei Chen, Chih-Hung Lai, Chieh-Shou Su, Wei-Chun Chang, Chi-Yen Wang, Kae-Woei Liang, Tsun-Jui Liu, Wen-Lieng Lee

“…Objective. Heavy calcifications remain formidable challenges to PCI, even for well-experienced operators. …”
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Characterization of an Endemic Plant Origanum grosii from Morocco: Trace Element Concentration and Antihyperglycemic Activities by H. El hassouni, M. Bouhrim, R. El hajji, M. Bnouham, A. Ziyyat, A. Romane

“…The results showed that the leaves exhibited a high concentration of trace elements (Ca, Mg, and K) and total absence of heavy metals, which were found in small quantities (Cr, Ni, and B) on the stems, and this makes the plant safe to use. …”
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PD-1/PD-L1 inhibitors related adverse events: A bibliometric analysis from 2014 to 2024 by Qingya Song, Zongliang Yu, Wenping Lu, Zhili Zhuo, Lei Chang, Heting Mei, Yongjia Cui, Dongni Zhang

“…Common adverse events included pneumonitis, myasthenia gravis, and vitiligo. There was a significant increase in multi-phase clinical trials and studies related to biomarkers. …”
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miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure by Yuran Wang, Zeming Wang, Han Hao, Yuwei Zhao, Jian Wang, Weixuan Wang

“…As a traditional neurotoxic heavy metal, Pb exposure results in neuroinflammation as well as neurodegenerative diseases. …”
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Development of Downscaled Climate Projections: A Case Study of the Red River Basin, South-Central U.S. by Darrian Bertrand, Renee A. McPherson

“…This area is prone to drought conditions and heavy precipitation events, and studies have consistently estimated that this will continue in the future. …”
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Field-based evidence for the prevalence of soil antibiotic resistomes under long-term antibiotic-free fertilization by Yuhao Fu, Fang Hu, Fang Wang, Min Xu, Zhongjun Jia, Wulf Amelung, Zhi Mei, Xiaozeng Han, Marko Virta, Xin Jiang, James M. Tiedje

“…Despite the influence of various factors like bacterial communities, soil properties, heavy metals, and MGEs, the MGEs had the most significant standardized effects on shaping ARGs through both direct and indirect pathways. …”
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A wireless sensor network for coal mine safety powered by modified localization algorithm by Hafiz Zameer ul Hassan, Anyi Wang, Ghulam Mohi-ud-din

“…According to some reports, there is heavy loss of life and money due to the occasional accidents in the coal mining area. …”
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A Node-Regulated Deflection Routing Framework for Contention Minimization by Bakhe Nleya, Andrew Mutsvangwa

“…However, the buffer-less nature of the interior nodes makes such networks prone to data burst contention occurrences that lead to a degradation in overall network performance as a result of sporadic heavy burst losses. Such drawbacks can be partly countered by appropriately dimensioning available network resources and reactively by way of deflecting excess as well as contending data bursts to available least-cost alternate paths. …”
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Public Finance and Debt Crises in Southern Africa: A Push for Central Banks over Parliaments by Dunia Zongwe

“…Instead, this paper proposes that SADC reallocates to central banks the heavy responsibility to act as stewards of sovereign debt management because the 2009 SADC Central Bank Model Law and the municipal laws that domesticated it have entrenched the independence of central banks from external interference and political pressure. …”
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Dye removal from textile wastewater using scoria-based of vertical subsurface flow constructed wetland system by Ribika Etana, Kenatu Angassa, Tolesa Getu

“…Abstract Textile wastewater poses significant risks if discharged untreated, especially due to the presence of synthetic dyes, salts, and heavy metals. As a result, constructed wetlands have emerged as a promising solution for sustainable textile wastewater management. …”
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Service users’ perception and attitude toward telemedicine-based treatment for substance use disorders: A qualitative study from India by Abhishek Ghosh, Tathagata Mahintamani, P. V. Aswathy, Debasish Basu, Surendra K. Mattoo, B. N. Subodh, Renjith R. Pillai, Manpreet Kaur

“…Results: Most participants were middle-aged men (40.5 years, 86.7%), dependent on two or more substances (86.7%), and had a history of chronic, heavy substance use (use ~16 years, dependence ~11.5 years). …”
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Ground Testing of a Miniature Turbine Jet Engine for Specific Flight Conditions by Ryszard Chachurski, Łukasz Omen, Andrzej J. Panas, Piotr Zalewski

“…The test program assumed and considered the acting loads and forces in both standard and specific flight conditions, including scenarios for a heavy rain. The preliminary evaluation of the investigation results provided data and insights required for further analysis. …”
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Maternal betel quid use during pregnancy and child growth: a cohort study from rural Bangladesh by Mohammad Redwanul Islam, Shaki Aktar, Jesmin Pervin, Syed Moshfiqur Rahman, Monjur Rahman, Anisur Rahman, Eva-Charlotte Ekström

“…Longitudinal studies following up those born to heavy users beyond childhood are warranted for capturing long-term implications of prenatal BQ exposure.…”
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Structural, Electronic, Elastic, Mechanical, and Opto-Electronic Properties for ZnAg2SnS4 and ZnAg2Sn0.93Fe0.07S4 Photocatalyst Effort on Wastewater Treatment through the First Pri... by Mohammad Jahidul Islam, Md. Sabbir Hasan Sohag, Unesco Chakma, Ajoy Kumer, Md. Monsur Alam, Mohammed Nazrul Islam Khan

“…First and foremost, the geometry optimization was performed by density functional theory (DFT) of the generalized gradient approximation (GGA) with Perdew–Burke–Ernzerhof (PBE)-ballpark figured as the successful candidate for computational screening containing heavy metal complexes. The structural geometry parameters were determined along with the electronic band structure, density of state (DOS), partial density of state (PDOS), Mulliken charge population, elastic constant, and optical characteristics. …”
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