Trafficking in cancer: from gene deregulation to altered organelles and emerging biophysical properties by Julie Patat, Kristine Schauer, Kristine Schauer, Hugo Lachuer

“…This complex and deadly disease stays a heavy burden for society, despite years of intense research activity. …”
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Intensité du travail et santé dans un organisme administratif : une enquête statistique à l’Agence nationale pour l’emploi by Anne-Françoise Molinié, Serge Volkoff

“…Participants mentioned insufficient workspace and heavy time pressure, and commented on the "lack of distance" in their everyday work. …”
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Analysis of Feature Fusion Based on HIK SVM and Its Application for Pedestrian Detection by Song-Zhi Su, Shu-Yuan Chen

“…Although neural network (NN) is an efficient tool for classification, the time complexity is heavy. Hence, we choose support vector machine (SVM) with the histogram intersection kernel (HIK) as a classifier. …”
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Immunoinformatic Analysis of Calcium-Dependent Protein Kinase 7 (CDPK7) Showed Potential Targets for Toxoplasma gondii Vaccine by Ali Taghipour, Sanaz Tavakoli, Mohamad Sabaghan, Masoud Foroutan, Hamidreza Majidiani, Shahrzad Soltani, Milad Badri, Ali Dalir Ghaffari, Sheyda Soltani

“…The aliphatic index with 68.78 and grand average of hydropathicity (GRAVY) with -0.331 score were estimated. The outcomes of current research showed that the CDPK7 protein included 502 alpha-helix, 1311 random coils, and 320 extended strands with GOR4 method. …”
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Strength Theory Model of Unsaturated Soils with Suction Stress Concept by Pan Chen, Changfu Wei, Jie Liu, Tiantian Ma

“…Once the new model is used to predict the change of shear strength, lots of time could be saved due to avoiding heavy and complicated strength tests of unsaturated soils. …”
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Modeling Spatial Social Complex Networks for Dynamical Processes by Shandeepa Wickramasinghe, Onyekachukwu Onyerikwu, Jie Sun, Daniel ben-Avraham

“…We develop a Spatial Social Complex Network (SSCN) model that captures not only essential connectivity features of real-life social networks, including a heavy-tailed degree distribution and high clustering, but also the spatial location of individuals, reproducing Zipf’s law for the distribution of city populations as well as other observed hallmarks. …”
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Probes for 4th Generation Constituents of Dark Atoms in Higgs Boson Studies at the LHC by M. Yu. Khlopov, R. M. Shibaev

“…The nonbaryonic dark matter of the Universe can consist of new stable charged species, bound in heavy neutral “atoms” by ordinary Coulomb interaction. …”
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Comparison and Analysis of Calculation Methods for Rated Static Load of Planetary Roller Screw Mechanism by Kang Xinhong, Wei Peitang, Hu Rui, Zhou Pengliang, Du Xuesong, Zhu Caichao

“…Planetary roller screw mechanism (PRSM) is a new type of heavy duty transmission devices. Rated static load is a key indicator to reflect its carrying capacity. …”
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Aliphatic, Cyclic, and Aromatic Organic Acids, Vitamins, and Carbohydrates in Soil: A Review by Valerie Vranova, Klement Rejsek, Pavel Formanek

“…Aliphatic, cyclic, and aromatic organic acids play important roles in rhizosphere ecology, pedogenesis, food-web interactions, and decontamination of sites polluted by heavy metals and organic pollutants. Carbohydrates in soils can be used to estimate changes of soil organic matter due to management practices, whereas vitamins may play an important role in soil biological and biochemical processes. …”
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Undigested Pills in Stool Mimicking Parasitic Infection by Fazia Mir, Ilyas Achakzai, Jamal A. Ibdah, Veysel Tahan

“…This pain was not associated with any trauma or recent heavy lifting. Upon presentation, the patient reported that for the last two months he started to notice pearly oval structures in his stool accompanying his chronic abdominal pain. …”
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A Synchronous Machine Transient Model Based upon an Algebraic Loop Accounting for Nonlinearity and Cross-Magnetization by R. Felicetti, U. Lundin

“…., of lookup tables). This can spare a heavy computational task, especially with very large lookup tables. …”
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Intent-driven cloud-network convergence on-demand orchestration by Lulu ZHANG, Chungang YANG, Dong WANG, Ying OUYANG, Tong LI, Junjie GUO, Ru DONG

“…With the rapid development of cloud computing and Internet technology, user service demands show a diversified development trend, and cloud-network convergence has become an important choice for the development of the current information and communication industry.At present, cloud-network convergence only achieves simple cloud-network interconnection, which can not overcome the heavy problems of diversified service demands and massive heterogeneous resource supply.Therefore, promoting cloud-network convergence still requires strengthening the on-demand delivery capability of cloud services.Intent-driven network, as a new networking paradigm, becomes a viable option to solve this dilemma.The research status of cloud-network convergence was sorted out, and the research necessity of intention-driven cloud-network convergence business on-demand orchestration was summarized.Furthermore, the intent-driven cloud-network convergence architecture and its key technologies were proposed and analyzed, and on this basis, an on-demand orchestration model of cloud business was proposed.Finally, in the hybrid cloud interconnection and industrial Internet scenarios, the intent-driven on-demand orchestration model of cloud business was analyzed, and the future prospects were introduced.…”
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MULTI-OBJECTIVE OPTIMIZATION DESIGN OF ROADHEADER’S CUTTING HEAD BASED ON THE GA by ZHAO LiJuan, FAN JiaYi

“…In order to improve the dynamic reliability of the roadheader,the roadheader’s rigid-flexible coupled model was established based on virtual prototyp,dynamic reliability analysis was done on the rotary table of different structural parameters,evaluation function was established based on mechanical optimization design theory,the function’s design variables was half cone angle,helix Angle and cutting line spacing, the function’s objective function was the minimization of maximum equivalent stress as the objective function.The cutting head’s optimal structural parameters was obtained by genetic algorithm.Based on the cutting productivity and rotary table equivalent stress, the optimal yawing speed was obtained by optimized multi-objective.The results shows that after two optimizations,rotary table maximum stress is decreased 18.495 MPa,the fatigue life is improved from 3.067 E4 to 3.326 E6,productivity is improved 18.6 t/h,prediction error is less than 1.3%,meet the design requirement.This method provides data support for the structure and kinematic parameters of cutting head,provides a new method for the optimization design of heavy complicated mechanical equipment.…”
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Simultaneous Adsorption and Degradation of Cr(VI) and Cd(II) Ions from Aqueous Solution by Silica-Coated Fe0 Nanoparticles by Yongchao Li, Hongpu Ma, Bozhi Ren, Tielong Li

“…Overall, the simply prepared Fe@SiO2 were potential material for the heavy metals removed from water.…”
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Ignoring Gender-Based Immunometabolic Reprograming, a Risky Business in Immune-Based Precision Medicine by Vijay Kumar

“…However, further research has indicated sex/gender-based immune differences, which further increase higher incidences of various autoimmune diseases (AIDs), such as systemic lupus erythematosus (SLE), myasthenia gravis, and rheumatoid arthritis (RA) in females. …”
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Economic impacts of floods in China and adaptation strategies under climate change by Ying Xue, Jun Xia, Yuan Liu, Lei Zou

“…Climate change has intensified the frequency and severity of heavy rainfall and flooding in China, posing serious threats to economic and social stability. …”
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In Situ Phytoremediation of Mine Tailings with High Concentrations of Cadmium and Lead Using <i>Dodonaea viscosa</i> (Sapindaceae) by Luis Fernando Acosta-Núñez, Patricia Mussali-Galante, María Luisa Castrejón-Godínez, Alexis Rodríguez-Solís, Joel Daniel Castañeda-Espinoza, Efraín Tovar-Sánchez

“…The waste generated during metal mining activities contains mixtures of heavy metals (HM) that are not biodegradable and can accumulate in the surrounding biota, increasing risk to human and environmental health. …”
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Perspectives and experiences regarding pre-exposure prophylaxis (PrEP) in a community sample of Veterans with unhealthy alcohol use: overall and across sexual orientation and gende... by Olivia V. Fletcher, Kristine Beaver, Elizabeth J. Austin, Jenna van Draanen, E. Jennifer Edelman, Emily C. Williams

“…Similar patterns were observed for severe unhealthy alcohol use and past-year frequent heavy episodic drinking. Generally, sexual/gender minoritized Veterans with unhealthy alcohol use reported more PrEP-affirming responses than those without but associations with unhealthy alcohol use were similar. …”
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Study of water pollution parameters in the dry and rainy seasons on the pollution index of the Mesuji River, Lampung, Indonesia by Abu Rosid Istomi, Suharso, Buhani, Tugiyono, Heri Satria, Emi Artika, Annisaa Siti Zulaicha

“…Phosphate levels were between 0.25 ± 0.11 and 0.47 ± 0.45 mg/L, while fecal coliform and total coliform ranged from 12.91 ± 4.22 to 22.97 ± 30.94 NPM/100 mL and 16.74 ± 6.61 to 25.43 ± 11.73 NPM/100 mL, respectively. Heavy metals were detected at concentrations between (4 × 10−4) ± (5 × 10−4) mg/L and 0.02 ± (8 × 10−4) mg/L. …”
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Soil moisture partitioning strategies in blowouts in the Hulunbeier grassland and response to rainfall by Zhixin Bao, Limin Yuan, Limin Yuan, Limin Yuan, Zhongju Meng, Ezhen Zhang, Lei Zhu, Jinwang Liu

“…The volumetric water content of soil in various parts of the blowouts under different rainfall amounts had significant differences, with rainstorms and heavy rainfall effectively recharging the blowouts to a depth of 200 cm, and the blowouts responded strongly to heavy rainfall (71.5 mm). …”
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