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32661
Defibrillation pad placement accuracy among Advanced Life Support instructors: A manikin-based observational study examining experience, self-evaluation, and actual performance
Published 2025-03-01“…Our novel analysis of pad angles and anterior-posterior analysis demonstrates that a significant portion of pads are incorrectly placed. …”
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32662
Characteristics and multi-omics analysis of spontaneous spondyloarthritis in non-human primates: Case report
Published 2025-01-01“…Its intricate pathological mechanisms have led to a scarcity of animal models capable of replicating the disease progression in humans, making it a prominent area of research interest in the field. …”
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32663
Maternal exposure to dim light at night induces behavioral alterations in the adolescent and adult offspring Wistar rat
Published 2025-01-01“…These results demonstrate that DLAN exposure induces intergenerational behavioral alterations that persist until adulthood.…”
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32664
2′-O-Methylperlatolic Acid Enhances Insulin-Regulated Blood Glucose-Lowering Effect through Insulin Receptor Signaling Pathway
Published 2022-01-01“…The purpose of this study was to determine whether 2-O-M functions as an activator of the insulin signaling pathway, regulating glucose hemostasis through the InsR and exerting a glucose-lowering effect in an animal model of diabetes. Methods. SPR-based analyses were used to detect the binding of different concentrations of 2-O-M to the InsR. …”
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32665
Influence of food availability on the diet and activity budget of two western lowland gorilla (Gorilla gorilla gorilla) groups of differing size in the Dzanga-Ndoki National Park,...
Published 2014-01-01“…We measured gorilla activity over six months by continuous focal sampling of 16 target animals rotated daily from both groups (N=9 and N=15). …”
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32666
Decreased SynMuv B gene activity in response to viral infection leads to activation of the antiviral RNAi pathway in C. elegans.
Published 2025-01-01“…Many synMuv B genes encode dREAM complex chromatin-regulatory proteins found in nearly all animals and plants. We show that mRNAs which are highly induced in synMuv B mutants are congruent with those induced by Orsay RNA virus infection, suggesting that the enhanced RNAi of synMuv B mutants may also be triggered by down-regulation of synMuvB gene activity in an Orsay virus infection of wild type. …”
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32667
Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence
Published 2025-02-01Subjects: Get full text
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32668
Functional Characteristics and Lipid Lowering Activity of Auricularia heimuer Soluble Dietary Fiber
Published 2025-01-01“…The obese animal model was constructed by high fat diet (HFD) C57BL/6J mice, and treated with A. heimuer soluble dietary fiber. …”
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32669
IMU Sensor-Based Worker Behavior Recognition and Construction of a Cyber–Physical System Environment
Published 2025-01-01“…In particular, methods such as using accelerometers and gyroscopes within MEMS sensors to acquire data based on workers’ angles, utilizing three-axis accelerometers and barometric pressure sensors to improve the accuracy of fall detection systems, and measuring the wearer’s gait using the x-, y-, and z-axis data from accelerometers and gyroscopes are being studied. …”
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32670
Optimal aspiration pressure of suction pump for oocyte retrieval in infertile patients undergoing in vitro fertilization.
Published 2025-01-01“…Existing studies, primarily in vitro and on animals, suggest that inappropriate aspiration pressures can impair oocyte quality. …”
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32671
Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice
Published 2025-01-01“…Additionally, the expression of Th2 cytokines (IL-4, IL-5 and IL-13) were found to be reduced, while the activation of dendritic cells (DCs) was inhibited. …”
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32672
The Śāriputra and Raudrākṣa – On the Identity of the Bronze Drum in the Dunhuang Murals
Published 2025-01-01“…The drum’s depiction in the contest scene reflects the clash between Buddhism and indigenous religious practices, symbolising the transition from animism and shamanism to Buddhist dominance. The broader cultural significance of this transformation highlights how Buddhism absorbed and transformed the religious symbols of local traditions, with the bronze drum serving as a metaphor for this shift. …”
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32673
HDAC and MEK inhibition synergistically suppresses HOXC6 and enhances PD-1 blockade efficacy in BRAFV600E-mutant microsatellite stable colorectal cancer
Published 2025-01-01“…Moreover, the combination therapy demonstrated the ability to enhance antitumor immunity by synergistically upregulating the expression of immune activation-related genes, activating the cyclic guanosine monophosphate–adenosine monophosphate synthase/stimulator of interferon genes (cGAS/STING) pathway, and diminishing the tumor cells’ DNA mismatch repair capacity. …”
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32674
Darnus tekstilės gaminių vartojimas tarp Lietuvos jaunimo
Published 2024-05-01“…Atlikus mokslinės literatūros analizę, buvo nustatyta, kad darnios tekstilės įgalinimo modeliai sietini su žiedinės ekonomikos vystymu. …”
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32675
Predicting pediatric patient rehabilitation outcomes after spinal deformity surgery with artificial intelligence
Published 2025-01-01“…., lordosis, sagittal vertical axis) and patient self-image beyond major Cobb angles to improve surgical decision-making for AIS patients. …”
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32676
Biochemical, Histological, and Multi-Omics Analyses Reveal the Molecular and Metabolic Mechanisms of Cold Stress Response in the Chinese Soft-Shelled Turtle (<i>Pelodiscus sinensis...
Published 2025-01-01“…The Chinese soft-shelled turtle (<i>Pelodiscus sinensis</i>), a type of warm-water reptile, is frequently chosen as the model animal to understand how organisms respond to environmental stressors. …”
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32677
Identification of Three Significant Genes Associated with Immune Cells Infiltration in Dysfunctional Adipose Tissue-Induced Insulin-Resistance of Obese Patients via Comprehensive B...
Published 2021-01-01“…Moreover, we verified the predicted hub genes by performing RT qPCR analysis in animals and human samples. Besides, the relative fraction of 22 immune cell types in adipose tissue was detected by using the deconvolution algorithm of CIBERSORT (Cell Type Identification by Estimating Relative Subsets of RNA Transcripts). …”
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32678
Power-sharing and Identity-Politics Transformation in Zanzibar, Tanzania
Published 2023-02-01“…This situation resulted in turbulent politics for many years with violence, killings, and hostility. In 2010, Zanzibar inters in the negotiation to solve the political problem that marred the island for a long time. …”
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32679
Effects of Iron and Vitamin C on Growth Performance, Iron Utilization, Antioxidant Capacity, Nonspecific Immunity, and Disease Resistance to Aeromonas hydrophila in Chinese Mitten Crab (Eriocheir sinensis)
Published 2023-01-01“…Iron is an essential trace element with an abroad physiological function, and iron deficiency can impair animal health. Vitamin C (VC) has the potential to release iron from diets and increase iron uptake. …”
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32680
Erbin Regulates Tissue Factors Through Ras/Raf Pathway in Coagulation Disorders in Sepsis
Published 2025-02-01“…However, the role of Erbin in coagulation disorders in sepsis and the relationship between Erbin and macrophage regulation of coagulation function are still unclear.Methods: At the cellular level, macrophages were treated with lipopolysaccharide (LPS) or MEK inhibitor (PD98059), protein expression levels were detected by Western blot, co-immunoprecipitation (Co-IP), and immunofluorescence, mRNA expression levels were detected by quantitative real-time polymerase chain reaction (qPCR), and the concentration of tissue factor (TF) in cell supernatant was detected by enzyme linked immunosorbent assay (ELISA). At the animal level, the cecal ligation and perforation (CLP) model was constructed in mice, and the inflammatory response and coagulation disorder of mice were observed by hematoxylin-eosin (HE) staining, immunohistochemistry, ELISA, and automatic hemagglutination analyzer. …”
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