Shift work schedules alter immune cell regulation and accelerate cognitive impairment during aging by Karienn A. de Souza, Morgan Jackson, Justin Chen, Jocelin Reyes, Judy Muayad, Emma Tran, William Jackson, M. Karen Newell-Rogers, David J. Earnest

“…These alterations in light-dark entrainment were closely associated with dramatic impairment in the Barnes maze test for the entire group of shifted LD mice at middle age, well before cognitive decline was first observed in aged (18-22mo) animals maintained on fixed LD cycles. In conjunction with the effects of circadian dysregulation on cognition, shifted LD mice at middle age were distinguished by significant expansion of splenic B cells and B cell subtypes expressing the activation marker CD69 or inflammatory marker MHC Class II Invariant peptide (CLIP), differential increases in CLIP+, 41BB-Ligand+, and CD74 + B cells in the meningeal lymphatics, alterations in splenic T cell subtypes, and increased number and altered functional state of microglia in the dentate gyrus. …”
Get full text

Effect of SOCO–SAP on moisture of different graded coal gangue and Elymus Dahuricus growth in alpine mining area by Zhilong SUN, Jianying YANG, Changqing SHI, Cheng LI, Ruijie LI, Xiaozhan WANG, Chunyan YANG, Monan DENG, Xinrui YANG, Jiajing LI

“…The higher the amount of SAP used, the stronger the ability to inhibit water infiltration. At the same mass fraction, the wetting front of different graded coal gangue reaches the bottom of the soil column. …”
Get full text

Bacteriological and Physicochemical Qualities of Ebutte River in Ebutte Community, Uhunmwonde Local Government Area, Edo State, Nigeria by Fred Osaro Ekhaise

“…The Ebutte River water quality studied based on the bacteriological and physicochemical parameters revealed that the human, animal and agricultural activities plays significant role in the contamination of the water source. …”
Get full text

PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection by Hao Jiang, Jiwei Gu, Haiyang Zhao, Sumit Joshi, Joel S. Perlmutter, Robert J. Gropler, Robyn S. Klein, Tammie L. S. Benzinger, Zhude Tu

“…The specificity of [18F]TZ4877 was assessed using S1PR1-specific antagonist, NIBR-0213, and S1PR1-specific DsiRNA pretreated the animals. Immunohistochemical studies were performed to confirm the increase of S1PR1 expression in response to infection. …”
Get full text

Altered functional brain connectivity in Dyt1 knock-in mouse models by R. Z. Adury, B. J. Wilkes, P. Girdhar, Y. Li, D. E. Vaillancourt, D. E. Vaillancourt, D. E. Vaillancourt

“…We also hypothesized that EMX mice would exhibit altered functional connectivity and activation patterns, supporting the idea that TorsinA dysfunction in the sensorimotor cortex alone can induce network abnormalities. In dGAG animals, we observed significantly lower functional connectivity between key sensorimotor nodes, such as the globus pallidus, somatosensory cortex, thalamus, and cerebellum. …”
Get full text

miR-9-5p/HMMR regulates the tumorigenesis and progression of clear cell renal cell carcinoma through EMT and JAK1/STAT1 signaling pathway by Xinyang Niu, Dingheng Lu, Weitao Zhan, Jiazhu Sun, Yuxiao Li, Yuchen Shi, Kai Yu, Suyuelin Huang, Xueyou Ma, Xiaoyan Liu, Ben Liu

“…Knocking down HMMR inhibited the proliferative and migratory abilities of ccRCC cells, while its overexpression amplified these oncogenic properties. …”
Get full text

Spotted fever group rickettsiae in black rats, pets, and humans in Zungarococha community, A rural area in the surroundings of Iquitos, Peru by Cusi Ferradas, Guillermo Salvatierra, David Payahuanca, Winnie Contreras, Andrés M. López-Pérez, Therangika A. Hangawatte, Diana León, Bruno M. Ghersi, Ricardo Gamboa, Katia Manzanares Villanueva, Viviana Pinedo-Cancino, Risa Pesapane, Gabriela Salmón-Mulanovich, Andrés G. Lescano, Janet Foley

“…There are scarce data on rickettsial ecology in rural areas of the Peruvian Amazon basin, where seroprevalence has not been determined, and the identities of animals acting as reservoirs of these bacteria are not known. …”
Get full text

Efficacy of carbonyl cyanide-3-chlorophenylhydrazone in combination with antibiotics against Mycobacterium abscessus by Jifang Zheng, Qiang Liu, Haoran Wang, Fengmin Huo, Junnan Jia, Hairong Huang, Suting Chen

“…The simultaneous use of CCCP with traditional antibiotics shows a synergistic effect across a wide range, significantly boosting the ability to inhibit the growth of M. abscessus throughout its growth phases. …”
Get full text

A Single-Mode 852-nm Faraday Laser by Zhiyang Wang, Zijie Liu, Jianxiang Miao, Hangbo Shi, Xiaomin Qin, Xiaolei Guan, Jia Zhang, Pengyuan Chang, Tiantian Shi, Jingbiao Chen

“…A single-mode Cs atom 852 nm Faraday laser, utilizing a corner cube retroreflector as the feedback element, is demonstrated and termed as a corner-cube-feedback Faraday laser. …”
Get full text

Assessment of the variability and correlation of biometric measurements in eyes with cataracts by Jian-Feng Zhao, Chen Yang, Jie Zhou, Hai-Yan Zhang, Yu Geng

“…Mean values for ACD, LT, Km, CCT, WTW, and angle kappa were found to vary with both age and gender. …”
Get full text

Efficacy of small-diameter core decompression with platelet-rich plasma in early osteonecrosis of the femoral head: a retrospective study by Haiwei Tang, Yahao Lai, Enze Zhao, Kai Zhou, Gang Chen, Zongke Zhou

“…Hip radiographs (X-rays and MRI) were evaluated using various ONFH staging systems (Preserved Angles, ARCO, JIC, and CHFJ stages). X-rays were performed at each follow-up to assess femoral head collapse and the rate of total hip arthroplasty (THA). …”
Get full text

Impacts of environmental quality and employment resilience during the coronavirus disease 2019 recession and recovery by D.O. Ayuningsih, L. Hakim, A. Suryantoro, I. Mafruhah, S. Hassan, E. Gravitiani, N.Q. Fathoni, A.I. Hakim

“…BACKGROUND AND OBJECTIVES: The unanticipated effects of the economic decline resulting from the coronavirus create both challenges and opportunities for assessing the ability of regions to achieve a balance between their economic demands and the preservation of the environment amidst the upheaval brought about by the pandemic. …”
Get full text

Gramíneas indicadores de condición en sitios de pastizal del sudoeste de Santiago del Estero by C. Kunst, R. Ledesma, E. Monti, J. Casillo, J. Godoy

“…Los datos de campo fueron complementados con información sobre preferencia animal extraída de la bibliografía. En las dos unidades de pastizal estudiadas, las especies Setaria lachnea, Trichloris pluriflora, Gouinia latifolia y Digitaria insularis indicaron, generalmente, condición buena-regular en los sitios alto y media loma, mientras que Pappophorum pappipherum, Paspalum spp y Trichloris pluriflora indicaron la misma condición en el sitio bajo. …”
Get full text

Reconstruction and computer analysis of the structural and functional organization of the gene network regulating cholesterol biosynthesis in humans and the evolutionary characteri... by A. D. Mikhailova, S. A. Lashin, V. A. Ivanisenko, P. S. Demenkov, E. V. Ignatieva

“…Cholesterol is an essential structural component of cell membranes and a precursor of vitamin D, as well as steroid hormones. Humans and other animal species can absorb cholesterol from food. Cholesterol is also syn­thesized de novo in the cells of many tissues. …”
Get full text

RNA m6A involves in regulation of oxidative stress and apoptosis may via NF-kB pathway in cadmium-induced lung cells by Nan Zhang, Jie Yang, Yuan Zhao, Wenhong Li, Bo Zhao, Rongxian Li, Zuoshun He, Shiyan Gu

“…It is also noteworthy that the results based on animals indicate that the relevant indicators and biological changes are partially similar to cell experiments. …”
Get full text

Pronuotos pėdos padėties sąsaja su vaikų dinamine laikysena. Vienmomentinis skerspjūvio tyrimas by Daiva Lenčiauskienė, Lina Levickienė, Roberta Bikuličienė, Jurgita Boltutienė, Monika Pocienė, Liudmila Kornejevienė

“…Tyrimo metu buvo taikomi šie tyrimo metodai: dinaminės laikysenos vertinimas, naudojant pritūpimų su iškeltomis virš galvos rankomis testą bei pėdos padėties vertinimas, naudojant pėdos padėties indekso apskaičiavimą, statistinė duomenų analizė, naudojant „Microsoft Office Excel 2020“ ir „IBM SPSS Statistics“ V 27.0 programas, požymių nepriklausomumo vertinimas, naudojant Chi-kvadrato kriterijaus skaičiavimą. …”

Social learning in bonobos: Learning of individual food preferences and copying despite better knowledge by Gladez Shorland, Emilie Genty, Klaus Zuberbühler

“…Over the past few decades there has been a growing interest into social learning in animals. The importance of social influence on food choice has been demonstrated across a number of species including humans. …”
Get full text

Co-Infection of <i>Culex tarsalis</i> Mosquitoes with Rift Valley Fever Phlebovirus Strains Results in Efficient Viral Reassortment by Emma K. Harris, Velmurugan Balaraman, Cassidy C. Keating, Chester McDowell, J. Brian Kimble, Alina De La Mota-Peynado, Erin M. Borland, Barbara Graham, William C. Wilson, Juergen A. Richt, Rebekah C. Kading, Natasha N. Gaudreault

“…This can have severe implications in areas where RVFV is endemic and convolutes our ability to anticipate transmission and circulation in novel geographic regions. …”
Get full text

Synthesis of novel titania nanoparticles using corn silky hair fibres and their role in developing a smart restorative material in dentistry by Afsheen Mansoor, Emaan Mansoor, Ezza Mansoor, Efrah Mansoor, Atta Ullah Shah, Uzma Asjid, João Filipe Brochado Martins, Sami Ullah Khan, Paulo J. Palma

“…Clinical significance: A new smart material containing titania-enriched glass ionomer cement showed its ability to significantly improve enamel shear bond strength and extend its storage life. …”
Get full text

A murine model of acute and prolonged abdominal sepsis, supported by intensive care, reveals time-dependent metabolic alterations in the heart by Bart Jacobs, Inge Derese, Sarah Derde, Sarah Vander Perre, Lies Pauwels, Greet Van den Berghe, Jan Gunst, Lies Langouche

“…For comparison, we included acutely septic mice killed at 30 h (acute sepsis, n = 15) and healthy controls animals (HC, n = 15). …”
Get full text