GATA1-mediated macrophage polarization via TrkB/cGMP–PKG signaling pathway to promote the development of preeclampsia by Wushan Li, Fei Hou, Di Cheng, Fengchun Gao, Jin Wang, Baoxia Cui

“…Transcriptomic sequencing, bioinformatics analysis, animal experiments, and clinical sample collection were conducted to validate the role of GATA1 in PE. …”
Get full text

Amoeba plate test with Acanthamoeba castellanii as an innovative tool for Nocardia recovery from sputum samples: a proof-of-concept study by Coralie Espinasse, Ghislaine Descours, Marine Ibranosyan, Laetitia Beraud, Christophe Ginevra, Joelle Chastang, Oana Dumitrescu, Frédéric Laurent, Verónica Rodriguez Nava, Sophie Jarraud, Camille Allam

“…This study reports Nocardia’s ability to grow in amoebic coculture, with some growth kinetic differences depending on the species, presumably implying their intra-amoebic multiplication. …”
Get full text

Orally administered prednisolone decreases plasma arginine vasopressin and serum copeptin concentrations in healthy dogs by Mathieu Victor Paulin, Dorsa Mehrabanpour, Suraj Unniappan, Elisabeth C. R. Snead

“…Objective Investigate plasma AVP (pAVP) and serum CoP (sCoP) concentrations in healthy dogs before, during, and after abrupt discontinuation of a long‐term course of orally administered prednisolone. Animals Eight healthy neutered young adult research Beagles. …”
Get full text

The Neosartorya (Aspergillus) fischeri antifungal protein NFAP2 has low potential to trigger resistance development in Candida albicans in vitro by Gábor Bende, Nóra Zsindely, Krisztián Laczi, Zsolt Kristóffy, Csaba Papp, Attila Farkas, Liliána Tóth, Szabolcs Sáringer, László Bodai, Gábor Rákhely, Florentine Marx, László Galgóczy

“…Genome analysis revealed non-silent mutations in only two genes in NFAP2-tolerant strains and in several genes in FLC-resistant strains. …”
Get full text

Choice white grease used for manufacturing a protein-encapsulated fat blend source for neonatal calves by David P. Casper, Mark F. Scott

“…The study objective was to evaluate CWG PEF as an alternative to a standard animal lard–tallow (ALT) PEF blend to mix a MR to be fed to Holstein calves. …”
Get full text

Performance of RIS-Secured Short-Packet NOMA Systems With Discrete Phase-Shifter to Protect Digital Content and Copyright Against Untrusted User by Nguyen Quang Sang, Hye-Young Kim, Tan N. Nguyen, Minh Bui Vu, Phuong T. Tran, Tran Trung Duy, Byung-Seo Kim, Miroslav Voznak

“…Meanwhile, to meet high spectrum utilization, Non-Orthogonal Multiple Access (NOMA) has emerged as a potential technology in the last decade, for its ability to serve multi-user communication simultaneously by exploiting power-domain rather than time or frequency domains. …”
Get full text

Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors by Romain Pacaud, Scott Thomas, Sibapriya Chaudhuri, Ann Lazar, Luika A. Timmerman, Pamela N. Munster

“…We hypothesized that benefit for this drug combination would only be specific to HRR deficient tumors, due to their inability to enact high fidelity DNA repair with subsequent cell death. …”
Get full text

Efficient Hydrolysis of Sugar Beet Pulp Using Novel Enzyme Complexes by Maria I. Komarova, Margarita V. Semenova, Pavel V. Volkov, Igor A. Shashkov, Alexandra M. Rozhkova, Ivan N. Zorov, Sergei A. Kurzeev, Aidar D. Satrutdinov, Ekaterina A. Rubtsova, Arkady P. Sinitsyn

“…Every year, tens of millions of tons of beet pulp are produced around the world. However, only a fraction of it is currently used, mainly as animal feed. …”
Get full text

Dietary Solid-state-fermentation product of Bacillus velezensis T23 alleviate hepatic steatosis, oxidative stress, gut barrier damage, and microbiota dysbiosis in juvenile genetica... by Qiang Hao, Rolf Erik Olsen, Einar Ringø, Qianwen Ding, Tsegay Teame, Yuanyuan Yao, Chao Ran, Yalin Yang, Zhen Zhang, Zhigang Zhou

“…The application of commensal probiotic bacteria is one of the preferable green feed additives for antibiotic substitution in aquaculture, while the application methods and detailed action mechanisms of commensal bacteria isolated from aquatic animals are not consistent with normal mammalian-derived probiotics. …”
Get full text

Development of standardized green coffee bean extract (Coffea canephora) into effervescent granules as an antioxidant supplement by Andre Wijaya, Farida Lanawati Darsono, Kuncoro Foe

“…The pH value of resulting EG-GCE products was within the range of 5.46-6.07, moisture content: 3.12-3.67%, flow rate: 25.78-28.53 g/s, angle of repose: 25.65-30.130, Hausner ratio: 1.14-1.22, Carr's index: 12.50–17.83%, dissolving effervescent granule time test: 1.00-1.33 min. …”
Get full text

Understanding phage BX-1 resistance in Vibrio alginolyticus AP-1 and the role of quorum-sensing regulation by Xiaoyu Li, Xin Liu, Tianyi Ma, Haochen Su, Bingrui Sui, Lili Wang, Bilal Murtaza, Yongping Xu, Na Li, Demeng Tan

“…The propagation of phages is primarily limited by their ability to adsorb to host cells and is further challenged by various bacterial defense mechanisms. …”
Get full text

Reverse Active Modification Method of Tooth Profile for RV Reducer Cycloidal Gear by Xiaotao An, Tianxing Li, Chunrong Xing, Guofeng Wang, Meng Tian

“…Through the contact analysis of the cycloidal pin wheel of RV transmission, the modification coefficient <italic>a_c</italic>, constant coefficient <italic>b</italic> and mismatch reference point meshing phase angle <inline-formula><alternatives><math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M2"><msub><mrow><mi>φ</mi></mrow><mrow><mn mathvariant="normal">0</mn></mrow></msub></math><graphic specific-use="big" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="alternativeImage/1C1259F9-6A00-465d-BC49-C413EFBA94A6-M002.jpg"><?…”
Get full text

Effect of concentric exercise-induced fatigue on proprioception, motor control and performance of the upper limb in handball players. by Stelios Hadjisavvas, Michalis A Efstathiou, Irene-Chrysovalanto Themistocleous, Katerina Daskalaki, Paraskevi Malliou, Christoforos D Giannaki, Jeremy Lewis, Manos Stefanakis

“…Although fatigue reduces reflex reaction time the effect is only marginal.…”
Get full text

Novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models by Shohei Koyama, Yujiro Naito, John D Minna, David E Gerber, Ryan R Kowash, Manoj Sabnani, Laura T Gray, Qing Deng, Nusrat U A Saleh, Luc Girard, Kentaro Masahiro, Zhiqian Lucy Liu, Hemanta Baruah, Esra A Akbay

“…Our antibody also effectively binds and stabilizes MICA/B expression in additional tumor types and demonstrates broad specificity. We show that in two KL mutant NSCLC xenograft models and a KL mutant PDX model, treatment with AHA-1031 monotherapy significantly inhibits tumor growth compared with vehicle-treated animals with no observable toxicity. …”
Get full text

İşletmelerin Malmquist-TFV Endeksi İle Verimliliklerinin Analizi: Tekstil Sanayi Örneği by Vural Çağlıyan, Emel Gelmez, Ramazan Göral

“…Çalışmada işletmelerin 2014-2016 dönemi Toplam Faktör Verimliliği ayrı ayrı değerlendirilmiş ve dönemler bazında değişimin kaynakları tespit edilmeye çalışılmıştır. Analize ilişkin hesaplamalar DEAP 2.1yazılımı ile gerçekleştirilmiştir. …”
Get full text

Transcriptomic and metabolomic analysis of recalcitrant phosphorus solubilization mechanisms in Trametes gibbosa by Yulan Chen, Akasha Farooq, XieLuyao Wei, Leitao Qin, Yong Wang, Lingzi Zhang, Quanju Xiang, Ke Zhao, Xiumei Yu, Qiang Chen, Xue Gao, Tashi Nyima, Petri Penttinen, Yunfu Gu

“…Although the phosphorus-solubilizing mechanisms of phosphate-solubilizing bacteria (PSB) have been well characterized, the mechanisms utilized by phosphate-solubilizing fungi (PSF) remain largely unexplored.MethodsThis study isolated a PSF strain, Trametes gibbosa T-41, from soil and evaluated its phosphorus solubilizing capacity with organic (calcium phytin; Phytin-P) and inorganic (tricalcium phosphate; Ca-P) phosphorus sources. …”
Get full text

SOCIALINIO DARBO SU PABĖGĖLIAIS IR PRIEGLOBSČIO PRAŠYTOJAIS YPATUMAI by Martyna Giedrimaitė, Aristida Čepienė

“…Vis dėlto pastebėta, kad kai kurios įstaigos yra linkusios bendradarbiauti, o iš kai kurių jaučiama bendradarbiavimo stoka. …”
Get full text

CYP3A5 promotes glioblastoma stemness and chemoresistance through fine-tuning NAD+/NADH ratio by Wentao Hu, Xiaoteng Cui, Hongyu Liu, Ze Li, Xu Chen, Qixue Wang, Guolu Zhang, Er Wen, Jinxin Lan, Junyi Chen, Jialin Liu, Chunsheng Kang, Ling Chen

“…Further in silico and patient tissue analyses validated the predictive ability of the GScore and identified a potential target, CYP3A5. …”
Get full text

Maternal Macronutrient Intake and Associated Risk for Gestational Diabetes Mellitus: Results from the BORN2020 Study by Antigoni Tranidou, Ioannis Tsakiridis, Emmanuela Magriplis, Aikaterini Apostolopoulou, Violeta Chroni, Eirini Tsekitsidi, Ioustini Kalaitzopoulou, Nikolaos Pazaras, Michail Chourdakis, Themistoklis Dagklis

“…Changes from pre-pregnancy to pregnancy showed significant increases in dietary fiber intake (aOR = 1.07, 95%CI: 1.04–1.10), protein (aOR = 1.00, 95%CI: 1.00–1.01), fat (aOR = 1.00, 95%CI: 1.00–1.01), vegetable protein (aOR = 1.01, 95%CI: 1.00–1.03), animal protein (aOR = 1.00, 95%CI: 1.00–1.01), and monounsaturated fatty acid (MUFA) intake (aOR = 1.01, 95%CI: 1.00–1.02), all of which were associated with increased GDM risk. …”
Get full text

Supplementation of Mulberry (Morus indica) and Vernonia (V. amygdalina) leaves as protein source on morphometric measurement, weight change, and carcass characteristics of sheep by Gezahegn Mengistu, Getnet Assefa

“…The design was randomized complete block design (RCBD) with five animals in each treatment and replication. Results The total DM intake (g day− 1) was significantly higher in D3 (771.4) than in D1 (722.8) and D5 (642.8) but similar to D2 (754.9) and D4 (759.7). …”
Get full text