Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus by Haoyi Yang, Yuwen Zhang, Yuxin Hong, Yuan Wei, Yuning Zhu, Lei Huang, Yuanxun Yang, Runbin Sun, Runbin Sun, Runbin Sun, Juan Li, Juan Li, Juan Li

“…ContextAs a novel SGLT1 inhibitor, SY-009 has been preliminarily confirmed in a phase Ib clinical study for its ability to reduce postprandial blood glucose in patients with type 2 diabetes mellitus (T2DM). …”
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The Quality of Functional Movements and the Back Squat in Amateur and Professional Bodybuilders by VERONIKA ILJINAITĖ, LAIMONAS ŠIUPŠINSKAS, KRISTINA BERŠKIENĖ

“…Greater experience in bodybuilding is associated with the compliance with several BSA criteria: trunk position, frontal knee alignment, tibial translation angle, foot position in all three back squat variations with different external loads, and descent with the training weight…”
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Pseudovibriamides from Pseudovibrio marine sponge bacteria promote flagellar motility via transcriptional modulation by Yitao Dai, Vitor Lourenzon, Laura P. Ióca, Dua Al-Smadi, Lydia Arnold, Ian McIntire, Roberto G. S. Berlinck, Alessandra S. Eustáquio

“…This gene cluster is also present in Pseudomonas bacteria that interact with terrestrial plants and animals. Here, we first assign functions to pseudovibriamide biosynthetic genes using reverse genetics. …”
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Evolutionary constrained genes associated with autism spectrum disorder across 2,054 nonhuman primate genomes by Yukiko Kikuchi, Mohammed Uddin, Joris A. Veltman, Sara Wells, Christopher Morris, Marc Woodbury-Smith

“…Rhesus macaques (Macaca mulatta) have been extensively used for preclinical neurobiological research because of remarkable similarities to humans across biology and behaviour that cannot be captured by other experimental animals. Methods We used the macaque Genotype and Phenotype (mGAP) resource consisting of 2,054 macaque genomes to examine patterns of evolutionary constraint in known human neurodevelopmental genes. …”
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Impact of maternal prenatal stress by glucocorticoids on metabolic and cardiovascular outcomes in their offspring: A systematic scoping review. by Claudia Eberle, Teresa Fasig, Franziska Brüseke, Stefanie Stichling

“…Peer-reviewed articles from January 2000 until August 2020 were included.<h4>Results</h4>Overall, n = 2.634 citations were identified, n = 45 eligible studies were included and synthesized according to their key findings. …”
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Occurrences and characteristics of forced marriages among girls married before the age of 16 in a Northern Nigerian State by Felix O. Sanni, Olumide F. Ajani, Elizabeth A. Sanni, Zachary T. Gwa, Michael O. Dada, Yemisi B. Alabi, Donald C. Udah, Jubril A. Kareem

“…Moreover, a considerable portion of respondents with no formal education (28.6%) and those who attended Qur’anic schools (25.5%) were compelled into marriage. …”
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Assessing and evaluating human-wildlife interactions for coexistence in shared landscapes by Katia Maria Paschoaletto Micchi de Barros Ferraz, Isabella de Freitas Bento, Anna Beatriz Queiroz Di Souza, Caio da Silveira Nunes, Maria Augusta de Mendonça Guimarães, Monicque Silva Pereira, Monicque Silva Pereira, Livia Lima da Silva, Letícia Keiko Nunes de Campos, Anita Seneme Gobbi, José Caio Quadrado Alves, Loisa Fabrícia Prates Alvarez, Silvio Marchini, Ana Carla Medeiros Morato de Aquino, Vinicius Kenji de Moraes Sato, Roberta Montanheiro Paolino, Roberta Montanheiro Paolino

“…We had a total of 570 events, of which 297 were characterized as encounters and 273 as HWI. We recorded 42 animal taxa related to the events, of which 36 interacted with humans, being Nasua nasua, Cairina moschata, and Didelphis albiventris the most frequent ones. …”
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Prediction and Evaluation of Water Resource Ecological Footprint in Beijing under the Influence of Changing Environment by QIN Huanhuan, HUANG Lixiang, WANG Jianquan

Subjects: “…sustainable water resource utilization…”
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Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine by Farhang H. Awlqadr, Kithar Rasheed Majeed, Ammar B. Altemimi, Arkan Mohammed Hassan, Syamand Ahmed Qadir, Mohammed N. Saeed, Aryan Mahmood Faraj, Tablo H. Salih, Alaa Jabbar Abd Al‐Manhel, Mazin A.A. Najm, Efstathia Tsakali, Jan F.M. Van Impe, Ahmed A. Abd El-Maksoud, Tarek Gamal Abedelmaksoud

“…Biodistribution, metabolism and the coccion of long-term effects studies must confirm safe and sustainable usage. To stimulate full utilization of nanotechnology in medicine and food science, further study must be undertaken to clear the existing drawbacks and discover other fields of the most appropriate applications of nanotechnology. …”
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The active roles of Rhodotorula mucilaginosa ZTHY2 in regulating antioxidant capacity and immune function of Leizhou black ducks by Jiang Wu, Yingxin Hu, Namula Zhao, Wei Yang, Zhibao Chen, Zhibao Chen

“…Previous studies in mice have demonstrated that Rhodotorula mucilaginosa ZTHY2 can promote animal growth, enhance antioxidant and immune functions, and regulate intestinal flora in our laboratory. …”
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In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei by Aboagye Kwarteng Dofuor, Temitayo Samson Ademolue, Karen Nana Akua Kuampah, Frederick Ayertey, Theresa Manful Gwira

“…At their maximum tested concentrations, the prepared fractions exhibited antioxidant absorbance intensities comparable to the reference antioxidant, Trolox, in contrast to the oxidant intensity of an animal antitrypanosomal drug, diminazene (Trolox, 0.11 A; diminazene, 0.65 A; AH-HEX, 0.20 A, AH-DCM, 0.20 A, AH-EA, 0.13 A, AH-AQ, 0.22 A). …”
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INTERRELATION OF PRIONS WITH NON-CODING RNAS by R. N. Mustafin, E. K. Khusnutdinova

“…As a result, the number of PrPSc increases exponentially. In the brain of animals and humans, transposon activity has been observed, which has a regulatory effect on the differentiation of neuronal stem cells. …”
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Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model by Sanghee Lim, Minhye Kwak, Jeonghan Kang, Melissa Cesaire, Kayen Tang, Robert W. Robey, William J. E. Frye, Baktiar Karim, Donna Butcher, Martin J. Lizak, Mahalia Dalmage, Brandon Foster, Nicholas Nuechterlein, Charles Eberhart, Patrick J. Cimino, Michael M. Gottesman, Sadhana Jackson

“…These findings indicate ibrutinib’s ability to increase brain endothelial permeability via junctional disruption and efflux inhibition, to increase BTB drug entry and prolong rodent glioma model survival. …”
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Socialinių tinklų galimybių taikymas Lietuvos viešojo transporto įmonių komunikacijoje by Adomas Taraskevičius

“…Taip pat pateikiami konkretūs siūlymai ir sprendimai, kaip būtų galima keleivių vežėjų komunikaciją socialiniuose tinkluose tobulinti.…”

Estimación de la digestibilidad in vitro mediante la técnica propuesta por Theodorou et al. (1994) by D. BOCANEGRA, D. ROCHINOTTI

“…Pasado este período se obtuvieron, por medio de una sonda nasogástrica, aproximadamente 300 centímetros cúbicos de fluido ruminal del animal que consumió sólo heno y 300 centímetros cúbicos de fluido ruminal de cada uno de los que consumió heno más suplemento. …”
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EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury by Shuangfei Ni, Bo Yang, Lei Xia, Huafeng Zhang

“…We used lipopolysaccharide (LPS) to induce inflammation of microglia, and we constructed the ASCI animal model. qRT-PCR detected the relative expression levels of EZH2, HIF-1α, miR-146a-5p, IL-6, TNF-α, IL-17, PKM2, GLUT1, and HK2 in cells and tissues. …”
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Early Changes in [18F]FDG Uptake as a Readout for PI3K/Akt/mTOR Targeted Drugs in HER-2-Positive Cancer Xenografts by Yanina Dockx, Christel Vangestel, Tim Van den Wyngaert, Manon Huizing, Sven De Bruycker, Patrick Pauwels, Steven Staelens, Sigrid Stroobants

“…CD-1 nude mice were inoculated with HER-2-overexpressing JIMT1 (trastuzumab-resistant) or SKOV3 (trastuzumab-sensitive) human cancer cells. Animals were treated with trastuzumab, everolimus (mTOR inhibitor), PIK90 (PI3K inhibitor), saline, or combination therapy. [18F]FDG scans were performed at baseline, two, and seven days after the start of the therapy. …”
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Fecal microbiota is more stable during degradation and more diverse for ex situ cheetahs in Namibia compared to the USA by Morgan A. Maly, Morgan A. Maly, Morgan A. Maly, Morgan A. Maly, Reade B. Roberts, Mia M. Keady, Anne Schmidt-Küntzel, Meagan Maxwell, Laurie Marker, Matthew Breen, Carly R. Muletz-Wolz, Adrienne E. Crosier

“…The relationships between gut microbiota and animal health are an important consideration increasingly influential in the management of wild and ex situ endangered species, such as the cheetah (Acinonyx jubatus). …”
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Clinical-grade extracellular vesicles derived from umbilical cord mesenchymal stromal cells: preclinical development and first-in-human intra-articular validation as therapeutics for knee osteoarthritis by Aliosha I. Figueroa-Valdés, Patricia Luz-Crawford, Yeimi Herrera-Luna, Nicolás Georges-Calderón, Cynthia García, Hugo E. Tobar, María Jesús Araya, José Matas, Darío Donoso-Meneses, Catalina de la Fuente, Jimena Cuenca, Eliseo Parra, Fernando Lillo, Cristóbal Varela, María Ignacia Cádiz, Rolando Vernal, Alexander Ortloff, Gino Nardocci, Verónica Castañeda, Catalina Adasme-Vidal, Maximiliano Kunze-Küllmer, Yessia Hidalgo, Francisco Espinoza, Maroun Khoury, Francisca Alcayaga-Miranda

“…In vitro studies evaluated the efficacy, safety, and potency of sEV; animal studies confirmed their effectiveness and safety. …”
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PASYVIOSIOS MAGISTRALĖS PANAUDOJIMAS OPTINĖS PRIEIGOS TINKLUOSE by Rimantas Plėštys, Jurgita Dabulytė-Bagdonavičienė, Gintaras Butkus

“…Interneto plėtra neatsiejama nuo informacijos perdavimo spartos didinimo tarp kompiuterių tinklo įrenginių, signalų perdavimui panaudojant optinius kabelius, kuriuose gali būti kelios dešimtys ar keli šimtai optinių skaidulų. Atskira optine skaidula, tuo pačiu metu, gali būti perduodama skirtingų informacijos šaltinių informacija panaudojant signalus, kurių bangų ilgiai yra skirtingi. …”
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