Neuroprotective role of epigallocatechin-3-gallate, albeginin and melanoxetin in alzheimer's disease by Arif Malik, Mehreen Hassan, Sulayman Waquar, Muhammad Wasim, Anam Naz, Faryal M. Awan, Muhammad T. Khan, Ali I. Khawaja, Sumera Zaib, Jamshed Iqbal, Ayesha Zahid, Marvi Marvi, Javeid Iqbal, Heng Wang, Dong-Qing Wei

“…Melanoxetin, a phenolic molecule, chelates toxic metals, lowers ROS, and protects neurons at 15–40 mg/kg/day in animal models and 50–150 mg/day in humans. These chemicals show promise for Alzheimer's treatment. …”
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Unveiling the role of ASPP1 in cancer progression: pan-cancer bioinformatics and experimental validation in colorectal cancer by Keyuan Xiao, Xiang Li, Ihsan Ullah, Wenqing Hu, Kaiqiang Wang, Fan Yang, Chengyu Yang, Chunqi Feng, Liang Zong, Xinghua Li

“…In vitro assays with colorectal cancer cell lines revealed significantly lower ASPP1 expression levels compared to normal colon cells (HCM460), and ASPP1 overexpression experiments showed a marked reduction in colorectal cancer cell proliferation, colony formation, invasion, and migration abilities. These cellular findings align with the bioinformatics predictions, highlighting ASPP1’s role as a suppressor of metastatic traits in colorectal cancer.ConclusionThis study highlights ASPP1 as a forecasting biomarker in the colorectal cancers and potentially across other cancers. …”
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Tyrosine hydroxylase of the brain and it’s regulation by glucocorticoids by E. V. Sukhareva, T. S. Kalinina, V. V. Bulygina, N. N. Dygalo

“…Moreover, our treatment led to increase in TH mRNA levels in 25- and 70-day-old animals, as well as an increase in enzyme activity in the brainstem and cerebral cortex of adult rats. …”
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The in ovo screening of 27 single essential oils showed selective effects on hatchability, performance and gene expression relevant to gut functions in broilers at hatch by Asad A. Khaskheli, Shahram Niknafs, Mila M.Y. Meijer, Xinle Tan, Peter R. Ferket, Eugeni Roura

Subjects: “…Essential oils…”
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Functional differentiation of human dental pulp stem cells into neuron-like cells exhibiting electrophysiological activity by B. Pardo-Rodríguez, A. M. Baraibar, I. Manero-Roig, J. Luzuriaga, J. Salvador-Moya, Y. Polo, R. Basanta-Torres, F. Unda, S. Mato, Gaskon Ibarretxe, Jose Ramon Pineda

“…For that, ex vivo differentiation protocols must be refined, especially to avoid the use of fetal animal serum. The aim of our study is to improve existing differentiation protocols of hDPSCs into neuron-like cells. …”
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Lactosuero, estabilizantes comerciales y fécula de maíz en la producción de helados artesanales by María Nelly Salazar Cerda, Jorge Antonio Gómez Martínez, Steven Paul Tablada Dávila, Robin Trinidad Flores Reyes, Roberto Carlos Larios González, Donald Alonso Juárez Gámez

“…Las variables evaluadas fueron pH, grasa (%), proteínas (%) solidos totales (%), solidos no grasos (%) y ceniza (%), sobre la base del análisis bromatológico según los procedimientos del laboratorio de bromatología de la Dirección de Ciencia Animal de la Universidad Nacional Agraria. El color, sabor, olor y textura se evaluó según una escala hedónica, con la participación de un panel no entrenado conformado por 53 personas. …”
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Super Dosing of IP6 Phytase in Phosphorus-Deficit Diets to Replace Added Phosphorus and Evaluate Growth Performance, Nutrient Digestibility and Bone Mineralization of Broiler Chick... by Bahadur Ali, Muhammad Irfan

“… Phosphorus in phytate is poorly available to monogastric animals due to their lack of the phytase enzyme, leading to increased phosphorus excretion and environmental pollution. …”
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Genetic variability and population structure analysis of Protostrongylus oryctolagi (Nematoda: Protostrongylidae) in Lepus europaeus from Central and Northern Italy. by Ilaria Guarniero, Laura Stancampiano, Rafaella Franch, Elisa Armaroli, Fabio Macchioni, Enrico Negrisolo

“…Nematodes are abundant and ubiquitous animals which are poorly known at intraspecific level. …”
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Furry neighbours: Acceptability of feeding and managing free‐ranging dogs and cats in an urban area by Danial Nayeri, Pourya Sardari, Fateme Zahra Raisi, Zahra Ghorbanian, Jenny Anne Glikman

“…We found that more than half of the respondents fed FRDs and FRCs (63% and 59%, respectively), and among those who fed FRDs and FRCs, 74.8% and 78.2% respectively used food leftovers from home to feed these animals. Furthermore, around half and one‐third of respondents provided FRDs and FRCs outside their neighbourhoods, respectively. …”
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Farklı sagittal yön iskeletsel paterne sahip bireylerde hava yolu hacminin değerlendirilmesi: Retrospektif pilot çalışma by Mukadder Orhan Gür, Mehmet Uğurlu

“…Yumuşak doku ve kraniyofasiyal iskeletin anatomik anomalileri, faringeal hava yolu boşluğunun hacmini ve morfolojisini değiştirebilir. Bu çalışmanın amacı, konik ışınlı bilgisayarlı tomografi (KIBT) ile sefalometrik analize dayalı sınıf I, II ve III iskeletsel paterne sahip hastaların hava yolu hacimlerinin karşılaştırılmasıdır.Gereç ve Yöntemler: Bu çalışma ortodontik tedavi amacıyla başvuran 46 bireyin KIBT kesitleri üzerinde yapıldı. …”
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Medio-Lateral Hamstring Muscle Activity in Unilateral vs. Bilateral Strength Exercises in Female Team Handball Players – A Cross-Sectional Study by Brian Sørensen, Per Aagaard, Lasse Malchow-Møller, Mette Kreutzfeldt Zebis, Jesper Bencke

“…Positive correlations were observed between knee joint angle and ST activity in kettlebell swing and deadlift…”
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The palmitoyl-CoA ligase Fum16 is part of a Fusarium verticillioides fumonisin subcluster involved in self-protection by Fabio Gherlone, Katarina Jojić, Ying Huang, Sandra Hoefgen, Vito Valiante, Slavica Janevska

“…ABSTRACT Fusarium verticillioides produces the mycotoxin fumonisin B1 (FB1), which disrupts sphingolipid biosynthesis by inhibiting ceramide synthase and affects the health of plants, animals, and humans. The means by which F. verticillioides protects itself from its own mycotoxin are not completely understood. …”
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CT45A1‐mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell‐in‐cell structure, potentiating the progression of microsatellite... by Hao‐Wei Teng, Hsiang‐Yueh Huang, Chun‐Chi Lin, Yuh‐Ching Twu, Wen‐Hao Yang, Wen‐Chun Lin, Hsin‐Yi Lan, Yen‐Yu Lin, Wei‐Lun Hwang

“…CT45A1‐expressing microsatellite stable (MSS) CRC cells showed enhanced migratory ability. However, CT45A1‐expressing MSI‐H CRC cells, but not MSS CRC cells, showed higher resistance to natural killer (NK) cell cytotoxicity and served as outer cells in homotypic CIC structures, preventing exogenous or therapeutic antibody access to inner CRC cells. …”
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Catabolic pathway acquisition by rhizosphere bacteria readily enables growth with a root exudate component but does not affect root colonization by Stephan Christel, Alyssa A. Carrell, Leah H. Hochanadel, Manuel I. Villalobos Solis, Paul E. Abraham, Sara S. Jawdy, Julie E. Chaves, Nancy L. Engle, Timkhite-Kulu Berhane, Tao Yao, Jin-Gui Chen, Wellington Muchero, Timothy J. Tschaplinski, Melissa A. Cregger, Joshua K. Michener

“…We find that pathway acquisition enables rapid catabolism of salicyl alcohol with only minor disruptions to the existing metabolic and regulatory networks of the new host. …”
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The probability of detecting host-specific microbial source tracking markers in surface waters was strongly associated with method and season by Claire M. Murphy, Daniel L. Weller, Tanzy M. T. Love, Michelle D. Danyluk, Laura K. Strawn

“…While many methods for understanding fecal contamination cannot differentiate between human and animal sources, microbial source tracking (MST) marker methods are used to identify fecal sources. …”
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Piloting creative engagement strategies to explore themes of parenthood with fathers by Iryna Culpin, Iryna Culpin, Catherine Lamont-Robinson, Mark Billington, Matthew James, James Prewett, Gareth Ward, Mireia Bes Garcia, Giovanni Biglino, Giovanni Biglino

“…Two further shorter sessions followed as fathers' key messages emerged, and the final forms of their own creative expressions crystallised.ResultsThe final pieces included a musical composition around sharing vulnerability as a new father, a word cloud to represent gendered language of parenthood, an animated graphic image representing the bond between father and child, a combination of short poetic stanzas highlighting assumptions around fatherhood, an experiential photographic record of a father and a son in the early years, and a cartoon strip around emotional intelligence in parenting.DiscussionArts-based participatory engagement enabled to capture deep-rooted experiences of being a father in modern society, illuminating common cultural and intergenerational perspectives, while also tapping into unique individual experiences. …”
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A generative whole-brain segmentation model for positron emission tomography images by Wenbo Li, Zhenxing Huang, Hongyan Tang, Yaping Wu, Yunlong Gao, Jing Qin, Jianmin Yuan, Yang Yang, Yan Zhang, Na Zhang, Hairong Zheng, Dong Liang, Meiyun Wang, Zhanli Hu

“…Additionally, clinical tolerance rates, which are determined by the tumor background ratio, have confirmed the ability of the method to distinguish highly metabolic regions accurately from normal regions, reinforcing its clinical applicability. …”
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Effects of Mixing Tree Species on Soil Enzyme Activity and Carbon-Use Efficiency in Eroded Masson Pine Forest by WANG Man, JIANG Yongmeng, ZHANG Shiliang, ZHANG Jinxiu, ZHENG Linmin, ZENG Zhiwei, LYU Maokui, XIE Jinsheng

“…However, it is unclear how tree species mixture affects soil extracellular enzyme stoichiometry and microbial carbon-utilization efficiency in single Pinus massoniana plantation in the eroded red soil area. …”
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Delivery of dendritic cells targeting 3M2e-HA2 nanoparticles with a CpG adjuvant via lysosomal escape of Salmonella enhances protection against H9N2 avian influenza virus by Futing Jia, Wenfeng Wang, Yawen Tian, Ainul Zahra, Yingkai He, Chongbo Ge, Tongyu Zhang, Mingyue Wang, Jingshuo Gong, Gerui Zhang, Guilian Yang, Wentao Yang, Chunwei Shi, Jianzhong Wang, Haibin Huang, Xin Cao, Yang Zeng, Nan Wang, Zhannan Wang, Chunfeng Wang, Yanlong Jiang

“…All the constructed plasmids were then transformed into the sifA gene-deficient Salmonella vector χYL56 for oral immunization.The results showed that sifA-deficient Salmonella could efficiently increase antigen-specific mucosal sIgA antibody titers, especially in alveolar lavage samples, whereas the presence of the phage-54 nanobody could dramatically increase intracellular IFN-γ mRNA levels, indicating its ability to enhance the Th1-type immune response. Finally, the presence of the CpG adjuvant clearly increased T-cell proliferation and promoted DC activation, with elevated splenic TLR21 levels observed. …”
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Effect of lethal yellow (AY) mutation and photoperiod alterations on mouse behavior by E. Y. Bazhenova, D. V. Fursenko, N. V. Khotskin, I. E. Sorokin, A. V. Kulikov

“…Six weeks old mouse males of AY/a and a/a lines were divided into four groups eight animals each and exposed to long- (14 h light and 10 h darkness) or short- (4 h light and 20 h darkness) day conditions for 28 days. …”
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