Human Primary Monocytes as a Model for in vitro Immunotoxicity Testing: Evaluation of the Regulatory Properties of TiO2 Nanoparticles by Svadlakova T, Kolackova M, Kulich P, Kotoucek J, Rosecka M, Krejsek J, Fiala Z, Andrýs C

“…While co-exposure of monocytes to MDP and TiO2 boosted NLRP3 activity, co-exposure to LPS and TiO2 inhibited NLRP3 by enhancing IL-10 release. The inhibitory effect of TiO2 on NLRP3 based on the promotion of IL-10 was confirmed in a post-exposure model for both costimulants.Conclusion: This study confirmed a non-negligible modulatory effect on primary monocytes in their inflammasome-based response and differentiation ability.Keywords: TiO2 nanoparticles, monocytes, macrophages, NLRP3, immunomodulation, polarization…”
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Therapeutic Effect of Yijinjing Rehabilitation Training Combined with Interference Current Therapy on Patients with Knee Osteoarthritis by XU Ming, LI Ya, QIN Shuang, LU Xiaoye, AI Kun, ZHANG Hong

Subjects: “…knee osteoarthritis…”
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A predictive risk‐scoring model for survival prognosis of multiple myeloma based on gain/amplification of 1q21: Experience in a tertiary hospital in South‐Western China by Yanqiu Xiong, Shanshan Liang, Wenjiao Tang, Li Zhang, Yuhuan Zheng, Ling Pan, Ting Niu

“…The model's discriminative ability was evaluated using the AUC in both the training and validation sets. …”
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Enzymatic Activity and Horizontal Gene Transfer of Heavy Metals and Antibiotic Resistant Proteus vulgaris from Hospital Wastewater: An Insight by Manzar Alam, Nilofer Bano, Tarun Kumar Upadhyay, Reem Binsuwaidan, Nawaf Alshammari, Amit Baran Sharangi, Radhey Shyam Kaushal, Mohd Saeed

“…This investigation intends to reveal the bacteria’s ability to transmit genes and their level of resistance as well. …”
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Comparative Analysis of Mechanistic and Correlative Models for Global and Bhutan-Specific Suitability of Parthenium Weed and Vulnerability of Agriculture in Bhutan by Sangay Dorji, Stephen Stewart, Asad Shabbir, Ali Bajwa, Ammar Aziz, Steve Adkins

“…However, a comparative analysis of these two approaches for parthenium weed is lacking, leaving a gap in understanding their relative effectiveness and ability to describe habitat suitability of parthenium weed. …”
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Evaluating and Enhancing Japanese Large Language Models for Genetic Counseling Support: Comparative Study of Domain Adaptation and the Development of an Expert-Evaluated Dataset by Takuya Fukushima, Masae Manabe, Shuntaro Yada, Shoko Wakamiya, Akiko Yoshida, Yusaku Urakawa, Akiko Maeda, Shigeyuki Kan, Masayo Takahashi, Eiji Aramaki

“…Three enhancement techniques of LLMs—instruction tuning, RAG, and prompt engineering—were applied to a lightweight Japanese LLM to enhance its ability for genetic counseling. The performance of the adapted LLM was evaluated on the 120-question dataset by 2 certified genetic counselors and 1 ophthalmologist (SK, YU, and AY). …”
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THE STRUCTURE OF HAPPINESS REPRESENTATION FOR RUSSIAN AND AMERICAN REPRESENTATIVES by S. Yu. Zhdanova, A. V. Pecherkina, A. A. Strokanov

“…Emotional state of students exerts direct impact on their ability and readiness to cope with challenges when studying, gives rise to the success of educational process and its effectiveness. …”
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Comparing clinical only and combined clinical laboratory models for ECPR outcomes in refractory cardiac arrest by Chun-Chieh Chiu, Yu-Jun Chang, Chun-Wen Chiu, Ying-Chen Chen, Yung-Kun Hsieh, Shun-Wen Hsiao, Hsu-Heng Yen, Fu-Yuan Siao

“…This study aims to compare a simpler clinical-only model with a model that includes both clinical and pre-ECMO laboratory parameters, to refine patient selection and improve ECPR outcomes. …”
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Comparative Evaluation of the Effectiveness of Manual and Electric Toothbrushes in Blind Children: A Randomised Controlled Trial by PS Thanalakshme, R Ramesh

“…Although research is limited, electric toothbrushes have been proposed as a solution to help blind children remove plaque more effectively by compensating for their reduced ability to visually monitor their brushing technique. …”
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Activity of Antiseptics Against <i>Pseudomonas aeruginosa</i> and Its Adaptation Potential by Tomasz M. Karpiński, Marzena Korbecka-Paczkowska, Mark Stasiewicz, Aleksandra E. Mrozikiewicz, Donald Włodkowic, Judyta Cielecka-Piontek

“…This study evaluated the activity of eight antiseptics against <i>P. aeruginosa</i>, assessed its ability to develop adaptation to these antiseptics, and, for the first time, determined the Karpinski Adaptation Index (KAI) for this bacterium. …”
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Fetal Spinal Cord Tissue in Mini-Guidance Channels Promotes Longitudinal Axonal Growth after Grafting into Hemisected Adult Rat Spinal Cords by Norman I. Bamber, Huaying Li, Patrick Aebischer, Xiao Ming Xu

“…Solid fetal spinal cord (FSC) tissue, seeded into semipermeable mini-guidance channels, was tested for the ability to promote axonal growth across the gap created by a midthoracic (T8) hemisection in adult rats. …”
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Urban green space during the Coronavirus disease pandemic with regard to the socioeconomic characteristics by R. Setiowati, R.H. Koestoer, K. Mizuno, H.S. Hasibuan

“…The pandemic stopped humans from visiting public amenities such as urban green spaces which are one of the key components of sustainable and livable cities and have the ability to reduce the negative impact on mental health. …”
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Determination of Sequential Well Placements Using a Multi-Modal Convolutional Neural Network Integrated with Evolutionary Optimization by Seoyoon Kwon, Minsoo Ji, Min Kim, Juliana Y. Leung, Baehyun Min

“…These findings underscore the M-CNN’s effectiveness in sequential well placement optimization, striking an optimal balance between predictive accuracy and computational efficiency. The method’s ability to dramatically reduce processing time while maintaining high accuracy makes it a valuable tool for enhancing oil field productivity and streamlining reservoir management decisions.…”
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Search for biocontrol agents among endophytic lipopeptidesynthesizing bacteria <i>Bacillus</i> spp. to protect wheat plants against Greenbug aphid (<i>Schizaphis graminum</i>) by S. D. Rumyantsev, V. Y. Alekseev, A. V. Sorokan, G. F. Burkhanova, E. A. Cherepanova, I. V. Maksimov, S. V. Veselova

“…We have for the first time demonstrated the aphicidal effect of fengycin and the ability of the fengycin-synthesizing strains and isolates, B. subtilis Ttl2, Bacillus sp. …”
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Forecasting Türkiye's Paper and Paper Products Sector Import Using Artificial Neural Networks by Kamil Abdullah Eşidir, Yunus Emre Gür

“…This study's application of ANNs offers a significant advancement by utilizing models that can better handle such complexities. …”
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Clinical Efficacy and Safety of Human Mesenchymal Stem Cell Therapy for Degenerative Disc Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Baocheng Xie, Shichun Chen, Yongxiang Xu, Weichao Han, Runkai Hu, Minyi Chen, Ruirong He, Shaobo Ding

“…Degenerative disc disease (DDD) can cause severe low back pain, which will have a serious negative impact on the ability to perform daily tasks or activities. For the past few years, mesenchymal stem cell (MSC) transplantation has emerged as a promising strategy for the treatment of DDD. …”
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Effective control of southern blight and root rot of Aconitum carmichaelii Debeaux by endophytic Bacillus velezensis YN-2-6S by Qian Wang, Yujie Qiu, Siyu Wang, Yumei Gou, Hongji Hou, Tianwei Su, Lan Zou, Jing Huang

“…Southern blight and root rot were two main soil-borne diseases of Aconitum carmichaelii Debeaux, a famous medicinal plant rich in alkaloids. …”
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Phosphate-modified CpG oligonucleotides induce in vitro maturation of human myeloid dendritic cells by A. A. Ostanin, O. Y. Leplina, E. A. Burakova, T. V. Tyrinova, A. A. Fokina, A. S. Proskurina, S. S. Bogachev, D. A. Stetsenko, E. R. Chernykh

“…Interestingly, the characteristic ability of LPS to enhance the expression of the co-stimulatory molecule OX40L on DCs was revealed only for the μ-analogue SD-101M. …”
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What’s Going On With Me and How Can I Better Manage My Health? The Potential of GPT-4 to Transform Discharge Letters Into Patient-Centered Letters to Enhance Patient Safety: Prospe... by Felix Eisinger, Friederike Holderried, Moritz Mahling, Christian Stegemann–Philipps, Anne Herrmann–Werner, Eric Nazarenus, Alessandra Sonanini, Martina Guthoff, Carsten Eickhoff, Martin Holderried

“…The resulting patient letters were analyzed for medical accuracy, patient centricity, and the ability to identify and translate the learning objectives. …”
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Prediksi Detak Jantung Berbasis LSTM pada Raspberry Pi untuk Pemantauan Kesehatan Portabel by Ahmad Foresta Azhar Zen, Eko Sakti Pramukantoro, Kasyful Amron, Viera Wardhani, Putri Annisa Kamila

“…Raspberry Pi dikenal karena ukurannya yang kecil, harga yang terjangkau, kinerja yang andal, dan efisiensi komputasi yang baik. …”
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