Bone marrow mesenchymal stem cells derived cytokines associated with AKT/IAPs signaling ameliorate Alzheimer’s disease development by Yalan Lu, Yanfeng Xu, Li Zhou, Siyuan Wang, Yunlin Han, Kewei Wang, Chuan Qin

“…Bone marrow-derived mesenchymal stem cells (BMMSCs) have emerged as a promising source for cellular therapy due to their ability to differentiate into multiple cell types and their paracrine effects. …”
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Anti-arthritic potential of crude sulfated polysaccharide from marine macroalgae Sargassum ilicifolium (Turner) C. Agardh: Regulation of cytokine cascade by Ramamoorthi Lavanya, Jeyabalan Srikanth, Sankar Seethalakshmi, Begum M. Yasmin, Duraipandian Chamundeeswari, Sekar Mahendran, Wong Ling Shing, Subramaniyan Vetriselvan

“…Seaweeds have been utilized as food, fodder, fertilizer, and medicine since ancient times; nevertheless, they have received only a little attention. …”
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Combination of Mangosteen (Garcinia mangostana L.) Pericarp Extract and Physical Exercise Decreases Atherosclerotic Lesions in Atherogenic Diet-Fed Rats by Andreas Arie Setiawan, . Sugiri, Awal Prasetyo, Eirin Yovita Kurniawan, Dominikus Evano Putra

“…Following eight weeks of treatment, the animals were sacrificed and the aortic tissues were taken for histological study. …”
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Serotype distribution and antimicrobial susceptibility of Streptococcus suis isolates from porcine diagnostic samples in Hungary, 2020–2023 by Ervin Albert, István Emil Kis, Krisztián Kiss, Katalin K-Jánosi, Tamás Révész, Imre Biksi

“…The brain, spleen, endocardial valve thrombus and lung proved to be the most frequent site of S. suis strain isolation, and animals 29–75 days of age were affected in the highest proportion. …”
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Spatial transcriptomics combined with single-nucleus RNA sequencing reveals glial cell heterogeneity in the human spinal cord by Yali Chen, Yiyong Wei, Jin Liu, Tao Zhu, Cheng Zhou, Donghang Zhang

“…Despite the greater understanding of glial cell types and functional heterogeneity achieved through single-cell and single-nucleus RNA sequencing in animal models, few studies have investigated the transcriptomic profiles of glial cells in the human spinal cord. …”
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US-guided high-intensity focused ultrasound in pancreatic cancer treatment: a consensus initiative between Chinese and European HIFU centers by Kun Zhou, Holger Strunk, Dobromir Dimitrov, Joan Vidal-Jove, Maria A. Gonzalez-Carmona, Markus Essler, Chengbin Jin, Zhechuan Mei, Hui Zhu, Milka Marinova

“…However, the current body of evidence is constrained by a lack of randomized controlled trials. The utilization of USgHIFU is primarily indicated for patients with unresectable, locally advanced, or metastatic pancreatic cancer, particularly those experiencing symptoms due to a locally advanced primary tumor.Methods: This collaborative consensus paper, involving European and Chinese HIFU centers treating pancreatic cancer, delineates criteria for patient selection, focusing on those most likely to benefit from USgHIFU treatment. …”
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The Inhibitory Effect of Connective Tissue Growth Factor Antibody on Postoperative Fibrosis in a Rabbit Model of Trabeculectomy by Kiana Hassanpour, Mozhgan Rezaei Kanavi, Narsis Daftarian, Azadeh Samaeili, Fatemeh Suri, Mohammad Pakravan, Azadeh Doozandeh, Sasha Afsar Aski, Maryam Fakhri, Afrooz Moghaddasi, Hamid Ahmadieh, Hamed Esfandiari

“…RNA extraction was performed on five eyes of the remaining rabbits which included one eye without any surgery, one eye 5 hr after trabeculectomy without any injection, one eye five days after trabeculectomy without any injection, and two eyes five days after trabeculectomy with administration of MMC and BSS, respectively. …”
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Rapid and noninvasive assessment of adductor muscle performance through shell-closing strength of Zhikong scallop Chlamys farreri by Xiangyi Zeng, Zujing Yang, Mingyi Sui, Zhi Liu, Qiang Xing, Liping Hu, Liming Jiang, Zhenmin Bao, Xiaoting Huang

“…Shell-closing strength (SCS) is a crucial trait of adductor muscle closely associated with the bivalve's swimming ability and health status. However, the investigation and practical application of SCS have been seriously hampered due to the limited availability and complexity of current measurement methodologies. …”
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Recombinant Anti-PF4 Antibodies Derived from Patients with Vaccine-Induced Immune Thrombocytopenia and Thrombosis (VITT) Facilitate Research and Laboratory Diagnosis of VITT by Luisa Müller, Venkata A. S. Dabbiru, Lucy Rutten, Rinke Bos, Roland Zahn, Stefan Handtke, Thomas Thiele, Marta Palicio, Olga Esteban, Marta Broto, Tom Paul Gordon, Andreas Greinacher, Jing Jing Wang, Linda Schönborn

“…Conclusions: The six rAbs derived from VITT patients reflect VITT-typical binding capacities and the ability to activate platelets. Therefore, these rAbs offer an attractive new option to study VITT pathophysiology.…”
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Imprint of ancestral and modern threats in human mind – experience of fear, disgust, and anger by Eva Landová, Eva Landová, Jakub Polák, Jakub Polák, Markéta Janovcová, Iveta Štolhoferová, Šárka Peterková, Aleksandra Chomik, Daniel Frynta

“…IntroductionThreats to our survival are often posed by the environment in which humans have evolved or live today. Animal and human ancestors developed complex physiological and behavioral response systems to cope with two types of threats: immediate physical harm from predators or conspecifics, triggering fear, and the risk of infections from parasites and pathogens leading to the evolution of the behavioral immune system (BIS) with disgust as the key emotion. …”
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Corticostriatal maldevelopment in the R6/2 mouse model of juvenile Huntington's disease by Carlos Cepeda, Sandra M. Holley, Joshua Barry, Katerina D. Oikonomou, Vannah-Wila Yazon, Allison Peng, Deneen Argueta, Michael S. Levine

“…There is a growing consensus that brain development in Huntington's disease (HD) is abnormal, leading to the idea that HD is not only a neurodegenerative but also a neurodevelopmental disorder. …”
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Wykorzystanie wskaźników altmetrycznych w Repozytorium Otwartych Danych Badawczych Uczelni Krakowskich (międzyuczelnianej platformie deponowania danych) by Leszek Szafrański, Marta Urbaniec

“…Artykuł ma zasadniczo dwa cele: analizę repozytoriów danych badawczych pod kątem wykorzystania w nich wskaźników altmetrycznych oraz ocenę, czy w repozytoriach działających na systemie do zarządzania danymi badawczymi Dataverse są uruchamiane metryki altmetryczne. …”
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The novel CD16A/anti-CD3 bifunctional protein, eCD16A/anti-CD3-BFP, redirects T cell cytotoxicity toward antibody-bound target cells by Chien-Ting Lin, Shang-Ju Wu, Cheng Hao Liao, Reyhung Roc Weng, Chun-Ming Lin

“…Functional characterization of eCD16A/anti-CD3-BFP was performed using in vitro, ex vivo, and in vivo animal assays. Combination treatments of eCD16A/anti-CD3-BFP with rituximab (anti-CD20), cetuximab (anti-EGFR), trastuzumab (anti-HER2) or anti-PD-L1 IgG1 led to specific killing of antigen-expressing tumor cells. …”
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LA GEOPEDOLOGIA COMO BASE PARA ZONIFICAR LA APTITUD FORESTAL EN UNA CUENCA DEL NOROESTE DE LA PATAGONIA ARGENTINA by Maria Cristina Frugoni, Romina González Musso, Gabriel Falbo, Dolores Zapiola

Subjects: “…Soil-Landscape relationships…”
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Climate-smart livestock nutrition in semi-arid Southern African agricultural systems by Felix Fushai, Teedzai Chitura, Oyegunle Emmanuel Oke

“…The keystone potential climate-smart alternative feedstuffs are identified to be the small cereal grains, such as sorghum (Sorghum bicolor) and pearl millet (Pennisetum glaucum) as dietary energy sources, the native legumes, such as the cowpea (Vigna unguiculata) and the marama bean (Tylosema esculentum) as protein sources, wild browse Fabaceae trees such as Vachellia spp. and Colophospermum mopane, which provide dry season and drought supplementary protein, minerals, and antioxidants, the non-fabaceous tree species such as the marula tree (Sclerocarya birrea), from which animals consume the energy and electrolyte-rich fresh fruit or processed pulp. …”
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Evaluating the Performance of Artificial Intelligence-Based Large Language Models in Orthodontics—A Systematic Review and Meta-Analysis by Farraj Albalawi, Sanjeev B. Khanagar, Kiran Iyer, Nora Alhazmi, Afnan Alayyash, Anwar S. Alhazmi, Mohammed Awawdeh, Oinam Gokulchandra Singh

“…Patients and health professional students commonly utilize these models due to their accessibility. The increasing use of LLMs in healthcare necessitates an evaluation of their ability to generate accurate and reliable responses. …”
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Diagnostic Accuracy of Detective Flow Imaging Endoscopic Ultrasonography for Evaluating Blood Flow Within Mural Nodules of Intraductal Papillary Mucinous Neoplasms by Kazuki Endo, Haruo Miwa, Kazuya Sugimori, Kozue Shibasaki, Shoichiro Yonei, Yugo Ishino, Shotaro Tsunoda, Hayato Yoshimura, Akihiro Funaoka, Hiromi Tsuchiya, Ritsuko Oishi, Yuichi Suzuki, Satoshi Komiyama, Takashi Kaneko, Manabu Morimoto, Kazushi Numata, Shin Maeda

“…This retrospective study evaluated the diagnostic accuracy of DFI-EUS and its ability to evaluate the blood flow of MNs in IPMNs. …”
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Deciphering of differences in gut microbiota and plasma metabolites profile between non-obese and obese Golden Retrievers dogs by Yazhen Cai, Huayu Tang, Guilin Xiang, Hongyu Yi, Jie Zhong, Zhaoxi Xie, Qinfeng Hu, Romaissaa El Bouhi, Pan Zhou, Yong Zhang, Honglin Yan

“…IntroductionGolden Retrievers have a high risk of obesity, which is prevalent in dogs and is associated with inflammation and cancer, impairing the health and life expectancy of companion animals. Microbial and metabolite biomarkers have been proposed for identifying the presence of obesity in humans and rodents. …”
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Regionalne zróżnicowanie polskiego rolnictwa a możliwości wdrażania polityk wspólnotowych by Stanisław Krasowicz

“…Niezbędna jest również bieżąca analiza zmian w politykach wspólnotowych, umożliwiająca podejmowanie działań dostosowawczychRealną oceną możliwości dostosowania produkcji roślinnej do wymogów i standardów Unii Europejskiej można uzyskać prowadząc analizę w mniejszych jednostkach administracyjnych niż województwo (subregiony, powiaty, gminy). …”
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Real-Time Neuropsychological Testing for Hydrocephalus: Ultra-Fast Neuropsychological Testing During Infusion and Tap Test in Patients with Idiopathic Normal-Pressure Hydrocephalus by Ilaria Guarracino, Sara Fabbro, Daniele Piccolo, Serena D’Agostini, Miran Skrap, Enrico Belgrado, Marco Vindigni, Francesco Tuniz, Barbara Tomasino

“…To select shunt-responsive patients, infusion and tap tests can be used. Only gait is evaluated after the procedure to establish a potential improvement. …”
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