A novel oncolytic Vaccinia virus armed with IL-12 augments antitumor immune responses leading to durable regression in murine models of lung cancer by Lijuan Chen, Lijuan Chen, Pengju Wang, Carmela Di Gioia, Ming Yuan, Zhe Zhang, Jinxin Miao, Wenli Yan, Guanghao Zhao, Yangyang Jia, Na Wang, Zhongxian Zhang, Haoran Guo, Giulia Marelli, Louisa Chard Dunmall, Nicholas R. Lemoine, Nicholas R. Lemoine, Yaohe Wang, Yaohe Wang

“…Importantly, rational combination of VVL-m12 and PD-1 blockade worked synergistically to significantly enhance survival of animals and safely cured lung cancer with no evidence of recurrence. …”
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The quality of Tibetan sheep meat from pastures was synergistically regulated by the rumen microbiota and related genes at different phenological stages by Xiaowei Chen, Yuzhu Sha, Xiu Liu, Yanyu He, Wenhao Li, Liangwei Yao, Jiqing Wang, Wenxin Yang, Qianling Chen, Min Gao, Wei Huang, Bin Ma, Bin Ma

“…Studies have shown that animal meat quality is related to the gut microbiota. …”
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Effect of daily alcohol intake on sex hormone levels among postmenopausal breast cancer survivors on aromatase inhibitor therapy: a randomized controlled crossover pilot study by Elizabeth Mostofsky, Julie E. Buring, Steven E. Come, Nadine M. Tung, Cancan Zhang, Kenneth J. Mukamal

“…Abstract Background Alcohol intake is associated with a higher risk of estrogen receptor-positive (ER+) breast cancer (BC), presumably through its confirmed ability to increase sex hormone levels. Whether consuming alcohol within the recommended limit of one serving per day increases sex hormone levels among postmenopausal women taking aromatase inhibitors (AI) to inhibit estrogen production remains unknown. …”
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SOCIALINIŲ PASLAUGŲ POREIKIO VERTINIMAS IŠ PASIŪLOS PERSPEKTYVOS: PANEVĖŽIO MIESTO SAVIVALDYBĖS ATVEJIS by Diana Micevičienė

“…Šia prasme minėtas ir augantis miesto savivaldybės – kaip pokyčių iniciatorės – vaidmuo. Kita vertus, tam tikrų sričių specialistų trūkumas, darbo krūvis, emocinis perdegimas, personalo motyvacijos stoka, neefektyvus socialinių paslaugų administravimas ir tarpinstitucinio bendradarbiavimo bei veiklos koordinavimo stoka įvadinti kaip spręstini pamatiniai klausimai, atsiremiantys į kvestionuotiną paslaugų kokybę. …”
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“If that would have lessened my symptoms, that would have been great...”: a qualitative study about the acceptability of tecovirimat as treatment for mpox by Sara Paparini, Rosalie Hayes, Benjamin Weil, Will Nutland, Ismael Maatouk, Teodora Wi, Chloe M. Orkin, Rosamund Lewis

“…Approval was granted under “exceptional circumstances” based on effectiveness found in pre-clinical challenge studies in animals and safety studies in humans showing minimal side effects. …”
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Qualitative evaluation of the Rehabilitation Exercise and psycholoGical support After COVID-19 InfectioN (REGAIN) randomised controlled trial (RCT): ‘you are not alone’ by Gordon McGregor, Susanne Finnegan, Martin Underwood, Joyce Yeung, James Mason, Peter Heine, Nigel Edwards, Julie Bruce, Kate Seers, Harbinder Kaur Sandhu, Helen Atherton, Sharisse Alleyne, Katie Booth, Ranjit Lall, Vivien P Nichols, Stuart Ennis, Scott McGuire, Rachel Potter, Jessica Smith, Chen Ji, Shilpa Patel, Henry Nwankwo, Kate Evans, Susie Hennings, Alastair Canaway, Grace Lobley, David Mcwilliams, Christina Jones, Emma Padfield, David Montgomery, Beatriz Lara, Becky Haley, Francesca Denton, Bartholomew Sheehan, Mariam Ratna, Elaine Fairbrother, Zoe Noakes, Bogdan Zutic, Lee Austin, Tom Forsyth, Anne Bush, Alan Bush, Patrick Sawdon, Jonathon Prosser, Lee Tompkins, Jonathon Guck, Danielle Hale, Juwairia Said, Georgie Ray, Rowena Williams, Gail Evans, Thillini Hettiarachchi, Abeesh Panicker

“…The themes from group exercise were: (1) monitoring and modification of the online exercise; (2) catering for differing abilities; (3) feeling safe and confident to exercise; (4) progression of fitness; (5) optimal timing in the recovery trajectory; (6) group effect; (7) initial apprehension about exercise group; (8) gauging exercise capabilities; (9) translating exercises into life; and (10) on-demand supplementary videos. …”
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Association between remnant cholesterol (RC) and endometriosis: a cross-sectional study based on NHANES data by Zeru Chen, Ruixuan Li, Jiajie Guo, Xiaorong Ye, Yang Zhou, Mingzhu Cao

“…In particular, an increase of one unit in RC was linked to a 135% rise in the likelihood of developing EMs. …”
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Nutritional and antioxidative characterization, antimicrobial and sensorial stability of flaxseed powder supplemented mutton patties by Raheel Suleman, Hira Choudhary, Muhammad Waseem, Jaza Maqbl Alshammari, Muhammad Muzamil, Huan Liu, Tariq Ismail, Muhammad Ammar Khan, Muhammad Qamar, Crossby Osei Tutu

“…Conclusively, owing to better potential of FP in improving the nutritional and microbial quality of mutton patties, the study further suggests its ability to act as a novel functional ingredient of choice in shelf-life extension of other food products.…”
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Genomic and mutational analysis of Pseudomonas syringae pv. tagetis EB037 pathogenicity on sunflower by Jude E. Maul, John Lydon, Dilip Lakshman, Colin Willard, Hyesuk Kong, Daniel P. Roberts

“…Transposon mutagenesis identified an additional 22 genes in loci, including two more plasmid-bound loci, involved in apical chlorosis on sunflower; some with known importance in other plant or animal pathosystems. Conclusions Apical chlorosis disease caused by Pstag EB037 is the result of a complex set of mechanisms. …”
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A novel LC-MS/MS analysis of vitamin D metabolites in mice serum and hair: impact of diet and light exposure by Muhammad K. Hakeem, Asma Al-Menhali, Sampath K. Elangovan, Iltaf Shah

“…Further research in this area has the potential to unveil additional factors influencing vitamin D metabolism, offering valuable insights into strategies for optimizing vitamin D levels in both animal models and human subjects.…”
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Analysis of the effect of cutting depth under thick immediate roof on gob-side entry retaining stability by WANG Fei, WANG Xuqiang, SHI Xinyu, XU Huicong

“…Field monitoring results showed that after entering the stable gob-side entry retaining section, the maximum subsidence of the roadway was 252 mm, the maximum load of the pressure-relief anchor cable was 412 kN, and the maximum working resistance of the stacking support was 41.9 MPa. …”
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One-Step Solid Extraction for Simultaneous Determination of Eleven Commonly Used Anticancer Drugs and One Active Metabolite in Human Plasma by HPLC-MS/MS by Shouhong Gao, Zhengbo Tao, Jingya Zhou, Zhipeng Wang, Yunlei Yun, Mingming Li, Feng Zhang, Wansheng Chen, Yejun Miao

“…Chromatographic separation was achieved on an Atlantis T3-C18 column (2.1 × 100 mm, 3.0 μm) with gradient elution using a mobile phase consisting of acetonitrile and 10 mM ammonium acetate plus 0.1% formic acid in water, and the flow rate was 0.25 mL/min. The Agilent G6410A triple quadrupole liquid chromatography-mass spectrometry system was operated under the multiple reaction monitoring mode with an electrospray ionization in the positive mode. …”
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Synbiotics effects of d-tagatose and Lactobacillus rhamnosus GG on the inflammation and oxidative stress reaction of Gallus gallus based on the genus of cecal bacteria and their me... by Yuanqiang Lv, Jie Chu, Xiaoxiao Zhang, Xuan Li, Aijiao Yin, Industrial Microbiology Laboratory

“…<h4>Results and conclusion</h4>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group's SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …”
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The first application of flush probe arrays on HL-3 tokamak by Z.H. Huang, L.W. Yan, K.Y. Yi, Na Wu, W.J. Chen, W.C. Wang, Yu He, J. Chen, J. Cheng, W. Zhao, J.M. Gao, L. Nie, Z.B. Shi, X.Q. Ji, W.L. Zhong

“…Forty-three signal wires at the same toroidal angle are combined into a manifold copper tube to vacuum feedthrough, which can dramatically shield noise and resist the high baking temperature of 300 °C. …”
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Early one-stage posterior-only surgery for congenital cervicothoracic scoliosis in children: medium- and long-term follow-up by Cefei Zhang, Fuyun Liu, Ke Xu, Weiming Hu, Bing Xia, Yufeng Zhao

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Evaluación de la calidad de subproductos de la soja by I. SEIJAS NOYA, G. JAURENA, M. WAWRZKIEWICZ, M. GAGGIOTTI, L.A. ROMERO, M. MÉNDEZ

“…Esto resulta problemático al momento de utilizarlos en dietas destinadas a producción animal. En el presente trabajo se analizó mediante ensayos químicos, in sacco y encuestas el perfil nutricional y la variabilidad de expellers y harinas de soja provenientes de la región de Rafaela, Santa Fe. …”
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Sustained Intraocular Pressure Rise after the Treat and Extend Regimen at 3 Years: Aflibercept versus Ranibizumab by Alper Bilgic, Laurent Kodjikian, Jay Chhablani, Anand Sudhalkar, Megha Trivedi, Viraj Vasavada, Vaishali Vasavada, Shail Vasavada, Samaresh Srivastava, Deepak Bhojwani, Aditya Sudhalkar

“…No significant visual field and RNFL changes were seen. The overall incidence was 8.91%. …”
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Optimal Inflow Performance Relationship Equation for Horizontal and Deviated Wells in Low-Permeability Reservoirs by Liqiang Wang, Zhengke Li, Mingji Shao, Yinghuai Cui, Wenbo Jing, Wei Zhang, Maoxian Wang

“…However, it is still unclear whether these inflow performance models (such as the Cheng, Klins-Majcher, Bendakhlia-Aziz, and Wiggins-Russell-Jennings types) are suitable for productivity evaluations of horizontal and deviated wells in low-permeability reservoirs. …”
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Protein kinases MpkA and SepH transduce crosstalk between CWI and SIN pathways to activate protective hyphal septation under echinocandin cell wall stress by Alexander G. Doan, Jessica E. Schafer, Casey M. Douglas, Matthew S. Quintanilla, Meredith E. Morse, Harley Edwards, Walker D. Huso, Kelsey J. Gray, JungHun Lee, Joshua K. Dayie, Steven D. Harris, Mark R. Marten

“…Previous studies have demonstrated that echinocandins fail against highly polarized fungi because they target only apical septal compartments. …”
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Genetic diversity of the Central European wild boar (Sus scrofa scrofa) population and domestic pig (Sus scrofa domesticus) breeds based on a microsatellite DNA locus by E. A. Snegin, V. M. Makeeva, A. P. Kaledin, A. M. Ostapchuk, I. D. Alazneli, A. V. Smurov

“…The low effective size of the wild boar population (Ne = 21.8, Neb = 4.0) is probably caused by the death and shooting of animals due to Pestis africana suum.…”
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