A new risk assessment model of venous thromboembolism by considering fuzzy population by Xin Wang, Yu-Qing Yang, Xin-Yu Hong, Si-Hua Liu, Jian-Chu Li, Ting Chen, Ju-Hong Shi

“…Many studies using machine learning (ML) models to predict VTE risk overlook the impact of class-imbalance problem due to the low incidence rate of VTE, resulting in inferior and unstable model performance, which hinders their ability to replace the Padua model, a widely used linear weighted model in clinic. …”
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Effect of a Vibration System on Pain Reduction during Injection of Dental Anesthesia in Children: A Randomized Clinical Trial by Muhanad AlHareky, Jehan AlHumaid, Sumit Bedi, Maha El Tantawi, Mazin AlGahtani, Yousef AlYousef

“…This study was registered with clinical trial registry of the United States National Institutes of Health (NIH) at ClinicalTrials.gov (NCT03953001).…”
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LncRNA GAS5 inhibits glioma progression through miR-135b-5p/APC axis by ZHANG Jidong, WANG Yutao, JI Jianwen

“…Moreover, dual luciferase reporter analysis were utilized to elucidate the regulatory mechanisms of GAS5 and miR-135b-5p/APC. …”
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Clinical Holistic Medicine: Metastatic Cancer by Søren Ventegodt, Elin Solheim, Mads E. Saunte, Mohammed Morad, Isack Kandel, Joav Merrick

“…We hope to be able not only to improve the quality of life, but also to improve survival and in some cases even induce spontaneous remission of the metastasized cancer. …”
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CD2AP deficiency aggravates Alzheimer’s disease phenotypes and pathology through p38 MAPK activation by Yan-Yan Xue, Zhe-Sheng Zhang, Rong-Rong Lin, Hui-Fen Huang, Ke-Qing Zhu, Dian-Fu Chen, Zhi-Ying Wu, Qing-Qing Tao

“…Abstract Background Alzheimer’s disease (AD) is the most common form of neurodegenerative disorder, which is characterized by a decline in cognitive abilities. Genome-wide association and clinicopathological studies have demonstrated that the CD2-associated protein (CD2AP) gene is one of the most important genetic risk factors for AD. …”
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Mechanism of melanoma suppression by Prosopis juliflora derived alkaloids: Apoptosis induction and signaling pathway inhibition by Jasoda Choudhari, Snehal K. Nimal, Shridhar Chougule, Trupti Shinde, N.R. Dhatrak, Gopal C. Kundu, Rajesh N. Gacche

“…In-vitro spheroid assay was performed to explored the PJLME-AF cytotoxic effects on tumour spheroid forming ability of melanoma cells. Additionally, the anti-tumor efficacy of PJLME-AF was tested in an in-vivo C57BL/6 mouse model. …”
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MHRA-MS-3D-ResNet-BiLSTM: A Multi-Head-Residual Attention-Based Multi-Stream Deep Learning Model for Soybean Yield Prediction in the U.S. Using Multi-Source Remote Sensing Data by Mahdiyeh Fathi, Reza Shah-Hosseini, Armin Moghimi, Hossein Arefi

“…Recent advances have highlighted the effectiveness and ability of Machine Learning (ML) models in analyzing Remote Sensing (RS) data for this purpose. …”
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β-Caryophyllene and Statins in Bone Fracture Healing – A Narrative Review by Marom H, Khan MA, Darvish N, Tornetta III P, Khoury A, Weil YA, Skelley NW, Allison DC, Meiron S, Ehrmann Barr T

“…BCP, a naturally occurring anti-inflammatory and antioxidant compound found in essential oils, enhances osteoblast activity and inhibits osteoclastogenesis. …”
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Rematuration Periods and Sperm Characteristics of Litopenaeus vannamei by L. Okmawati Anwar, K. Sumantadinata, O. Carman

“… The reproduction ability of male has an important role in seeds production of Litopenaeus vannamei. …”
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Obstacle recognition and elimination method for humanoid robots based on point cloud processing by Naigong YU, Qiusheng XIE, Hongzheng LI

“…In stair parameter estimation experiments, obstacles significantly hinder the humanoid robot’s ability to accurately measure step height and depth. …”
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The effect of acute branched-chain amino acids ingestion on rate of force development in different time intervals: a controlled crossover study by Xi-Nuan Zhang, Long-Ji Li, Yan-Hao Tu, Li-Feng Zhang, Hua-Yu Shang, Meng Liu, Ming-Da Li

“…Additional outcome measures, including strength and jump tests, agility and sprinting tests, and physiological responses, were also assessed. …”
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Impact of Year and Genotype on Benzoxazinoids and Their Microbial Metabolites in the Rhizosphere of Early-Vigour Wheat Genotypes in Southern Australia by Paul A. Weston, Shahnaj Parvin, Pieter-W. Hendriks, Saliya Gurusinghe, Greg J. Rebetzke, Leslie A. Weston

“…Wheat (<i>Triticum aestivum</i>) is grown on more arable acreage than any other food crop and has been well documented to produce allelochemicals. …”
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Computational insights into Sitahe (Leuconotis eugenifolia) bioactive compounds: A promising approach for radioprotection through p53 inhibition by Dian Pribadi Perkasa, Iin Kurnia, Taufik Muhammad Fakih, Teja Kisnanto, Dwi Ramadhani, Harry Nugroho Eko Surniyantoro, Boky Jeanne Tuasikal, Alfian Mahardika Forentin, Mukh Syaifudin

“…Molecular docking studies identified strong binding affinities between these compounds and the p53 DNA binding domain, with baurenol demonstrating the highest binding affinity at −6.75 kcal/mol, which is better compared to rhazinilam (−4.55 kcal/mol), leuconolam (−4.36 kcal/mol), leuconoxine (−4.26 kcal/mol), and dehydroleuconoxine (−4.76 kcal/mol). …”
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Development and Validation of a Predictive Model Based on Serum Silent Information Regulator 6 Levels in Chinese Older Adult Patients: Cross-Sectional Descriptive Study by Yuzi You, Wei Liang, Yajie Zhao

“…ConclusionsSIRT6 shows promise in predicting CAD, with enhanced predictive abilities when combined with the TyG index. In clinical settings, monitoring fluctuations in SIRT6 and TyG may offer valuable insights for early CAD detection. …”
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Determinants of school-going adolescent girls’ health and nutritional status in district Malir, Karachi: a baseline cross-sectional study by Saira Zafar, Babar Tasneem Shaikh, Zoha Imtiaz Malik, Abdul Momin Rizwan Ahmad

“…Adequate nutrition is essential during this developmental stage, leading to significant physical performance, improved cognitive ability, and productivity. Improving adolescent girls’ nutrition is crucial for breaking the intergenerational cycle of malnutrition, but research in Pakistan has largely focused on children under five and pregnant women, often neglecting this vulnerable group.ObjectiveThis study aimed to determine the contextual and sociodemographic factors contributing toward undernutrition to improve the health and nutritional status of adolescent girls.MethodsA school based cross sectional study was conducted as the baseline survey for a mixed methods study leading to a pilot cluster randomized controlled trial. n = 84 girls (10–14 years) from two public schools were selected by simple random sampling. …”
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Anti-Inflammatory and Anti-Migratory Effects of Morin on Non-Small-Cell Lung Cancer Metastasis via Inhibition of NLRP3/MAPK Signaling Pathway by Punnida Arjsri, Kamonwan Srisawad, Sonthaya Umsumarng, Pilaiporn Thippraphan, Songyot Anuchapreeda, Pornngarm Dejkriengkraikul

“…Our findings demonstrated the significant ability of morin to decrease the production of IL-1β, IL-18, and IL-6 in a dose-dependent manner (<i>p</i> < 0.05), as well as suppress NSCLC cell migration and invasion. …”
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Correlation Analysis of Twig and Leaf Characteristics and Leaf Thermal Dissipation of <i>Hippophae rhamnoides</i> in the Riparian Zone of the Taohe River in Gansu Province, China by Qun Li, Min Ma, Yurui Tang, Tingting Zhao, Chengzhang Zhao, Bo Li

“…<b>Aims</b>: The functional traits of twigs and leaves are closely related to the ability of plants to cope with heterogeneous environments. …”
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Knowledge, attitudes, and beliefs regarding acute coronary syndrome in patients with type 2 diabetes: a cross-sectional study by Mohammad Amerzadeh, Mahdie Bahrami, Mojtaba Senmar, Zahra Hosseinkhani, Zahra Shafiei Kisomi

“…Patients had a low attitude towards heart disease, with approximately 36.4% being somewhat or completely confident in their ability to assist others with a heart attack. Regarding performance, 45.7% of individuals believed that they should promptly go to the hospital during a heart attack. …”
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Physicians’, pharmacists’, and nurses’ education of patients about antibiotic use and antimicrobial resistance in primary care settings: a qualitative systematic literature review... by Lavinia Bianca Balea, Ragnhild J. A. Gulestø, Hongxuan Xu, Hongxuan Xu, Stinne Glasdam

“…Two main themes emerged: (1) Relationships between professionals and patients influenced educational strategies, showing that trust and rapport between healthcare professionals and patients played a crucial role in shaping educational strategies around antibiotic use; (2) The organizational structures challenged professionals in guiding and educating patients, highlighting how limited resources, time constraints, and system-level pressures hindered healthcare professionals’ ability to provide consistent and effective education. …”
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External validation and revision of the Lafontaine criteria for unstable distal radius fractures: a retrospective study by Pornpanit Dissaneewate, Phatklao Thanavirun, Yanin Tangjaroenpaisan, Kantapon Dissaneewate

“…Therefore, we aimed to evaluate the Lafontaine criteria as a diagnostic prediction rule for distal radius fractures, assess the inter-rater reliability and predictive ability of various parameters for distal radius instability, and develop new criteria for fracture instability using reliable and highly predictive factors. …”
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