Characterisation of pregnancy-induced alterations in apolipoproteins and their associations with maternal metabolic risk factors and offspring birth outcomes: a preconception and l... by Li Chen, Karen Mei-Ling Tan, Melvin Khee-Shing Leow, Kok Hian Tan, Jerry Kok Yen Chan, Shiao-Yng Chan, Yap Seng Chong, Peter D. Gluckman, Johan G. Eriksson, Markus R. Wenk, Sartaj Ahmad Mir

“…The Singapore Lipidomics Incubator (SLING) is supported by grants from the National University of Singapore via the Life Sciences Institute, the National Research Foundation (NRF, NRFI2015-05 and NRFSBP-P4) and A∗STAR IAF-ICP I1901E0040. Additional funding is provided by Institute for Human Development and Potential (IHDP)—Agency for Science, Technology and Research (A∗STAR), Singapore.…”
Get full text

Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks by Chen Shaopeng, Cui Changze, Qi Youpeng, Mi Baohong, Zhang Meixian, Jiao Chenyue, Zhu Chune, Wang Xiangyan, Hu Jiang, Hu Jiang, Shi Bingang, Shi Bingang, Ma Xueming, Zhao Zhidong, Zhao Zhidong, Zhang Xiaolan

“…Among these, the propionic acid concentration in the jejunum was significantly lower than in the abomasum and colon. Additionally, correlation analysis results indicated that acetic acid and butyric acid were significantly positively correlated with the ruminal bacterial community (p < 0.05). …”
Get full text

Should the Food and Drug Administration Limit Placebo-Controlled Trials? by Max Goodman, Connor Pedersen

“…Ann Afr Med. 2017;16(3):97-100. doi:10.4103/aam.aam_211_16; Rothman KJ, Michels KB. …”
Get full text

Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) by Junyu Yan, Kai Luo, Bo Wang, Jiaxin He, Can Li, Jiang Zhou, Wenhao Lai, Xin Zhou, Jingwei Ye, Mingzhu Pan, Yingbing Su, Weihua Gao, Kai Guo, Chengmin Zhao

“…A total of 648 fish with similar initial body weight (143.77 ± 0.73 g) were randomly placed into 18 tanks, with 36 fish in each tank. …”
Get full text

High-quality targeted temperature management combined with decompressive craniectomy in patients with poor-grade aneurysmal subarachnoid hemorrhage: a secondary analysis of a multi... by Yang Liu, Bingsha Han, Yanru Li, Zhiqiang Ren, Yong Chen, Ming Zhang, Jiao Li, Jv Wang, Fan Yang, Mengyuan Xu, Jiaqi Zhang, Pengzhao Zhang, Tiancai Wang, Jinying Tian, Guang Feng

“…After propensity score matching, the TTM combined with DC improved favorable outcome at 3 months (mRS 0–3: 61% vs. 22%, OR 5.50, 95%CI 1.36–26.3, p = 0.022). In addition, the TTM-DC group increased GCS score at discharge compared with the DC-alone group (9 vs. 3, β 2.58, 95%CI 0.32–4.84, p = 0.032). …”
Get full text

Économie végétale à partir des études carpologiques du boulevard Dr Henri-Henrot à Reims/Durocortorum by Véronique Matterne

“…From the 2nd c. onward, choice of meats is more varied, with the addition of poultry, game, and seafood (Toulemonde et al. 2017). …”
Get full text

Xixin Decoction’s novel mechanism for alleviating Alzheimer’s disease cognitive dysfunction by modulating amyloid-β transport across the blood–brain barrier to reduce neuroinflamma... by Chaokai Yang, Enlong Zhao, Hu Zhang, Liqi Duan, Xinyue Han, Hongli Ding, Yan Cheng, Dengkun Wang, Dengkun Wang, Dengkun Wang, Xiaojing Lei, Xiaojing Lei, Xiaojing Lei, Yongchang Diwu, Yongchang Diwu, Yongchang Diwu

“…In vivo studies demonstrated that XXD improved spatial learning and memory abilities in SAMP8 mice, reduced the amount of Evans blue extravasation in brain tissues, modulated the BBB-associated P-gp/ECS axis, RAGE/LRP1 receptor system, as well as MRP2 and Mfsd2a proteins, and decreased the accumulation of Aβ in the brains of SAMP8 mice. Additionally, XXD upregulated the expression of TREM2, downregulated IBA1, TLR1, TLR2, and CMPK2 expression, and reduced the levels of pro-inflammatory factors NLRP3, NF-κB p65, COX-2, TNF-α, and IL-1β in the hippocampal tissues.ConclusionXXD may exert its effects by regulating the P-gp/ECS axis, the RAGE/LRP1 receptor system, and the expression of MRP2 and Mfsd2a proteins, thereby modulating the transport function of the BBB to expedite the clearance of Aβ, reduce cerebral Aβ accumulation, and consequently inhibit the activation of microglia induced by Aβ aggregation. …”
Get full text

Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis by Bing Xia, Yan-lin Lu, Jin Peng, Jing-wei Liang, Fang-qin Li, Jiu-yang Ding, Chang-wu Wan, Cui-yun Le, Jia-lin Dai, Jie-Wang, Bing Guo, Jiang Huang

“…ROC curve analysis revealed GAL8 DNA methylation as an independent risk factor for atherosclerosis: GAL8, along with inflammation-related proteins MCP-1, MMP9, and TNF-α, were upregulated in the mouse lesion group, while expression of autophagy-related proteins LC3 and Beclin1 was downregulated. Additionally, phosphorylated MAPK/mTOR pathway proteins were detected in the mouse model of atherosclerosis. …”
Get full text

Study on applicability of Death Attitude Profile-Revised in medical students (死亡态度描绘量表在医学生中的适用性研究) by CHEN Qiannan (陈倩楠), ZHANG Jing (张静), QIAN Zhigang (钱志刚)

“…Except for item 1, the load of other items on the corresponding factor was greater than 0. 4. In addition to the naturally accepted dimension, the r value of other dimensions ranged from 0. 208 to 0. 709, and the r value between dimension and total scale ranged from 0. 663 to 0. 834. …”
Get full text

Clinical observation of Shenfu injection in treating patients with internal watershed cerebral infarction (参附注射液治疗内分水岭脑梗死临床观察) by YANG Junhang (杨俊行), LI Jie (李杰), HU Zhe (胡哲), FU Jingna (付景娜), FENG Huimin (冯慧敏)

“…Patients in the experimental group were additionally given Shenfu injection for 14 days as a course of treatment. …”
Get full text

Surgeons are apprehensive to use DCD lungs despite similar post-transplant outcomes: A 20-year UNOS retrospective analysis by J. Sam Meyer, MSc, Oliver K. Jawitz, MD, MHS, Yury Peysakhovich, MD, Dan Aravot, MD, Matthew G. Hartwig, MD, MHS, Yaron D. Barac, MD, PhD

“…DCD, and 2.43 [95% 1.83, 3.22, p < 0.001] times higher than patients >50 in DBD vs DCD donors. In addition, for each era, the odds for procuring DCD vs. …”
Get full text

Characteristics of the Volunteer Service Management System for National Parks in the United Kingdom by Tianyi REN, Chuanbo HONG, Yinglin WANG

“…Meanwhile, on the basis of literature review, this research searches relevant official data on the first batch of national parks announced in China, analyzes such contents as management documents, activity management, and personnel recruitment management, and compares the same horizontally with the volunteer service management system for national parks in the UK so as to analyze the shortcomings of the volunteer service management system for national parks in China and put forward corresponding suggestions.ResultsThe research finds that the 14 national parks in the UK have sound volunteer service management policies, management system structures and volunteer recruitment websites, as well as open and transparent volunteer screening mechanisms and volunteer feedback channels. In addition, most of the national parks have public data on the management of volunteer service funds, and a small number of national parks have public statistics on the number of volunteers and the total number of volunteer hours per year. …”
Get full text

[Translated article] Surgical treatment of ipsilateral bifocal tibial fractures: A challenge for the surgeon by A. Ortega-Yago, M. Barrés-Carsí, A. Balfagón-Ferrer

“…Conclusions: Bifocal tibia fractures can be treated using a combination of intramedullary nailing and plate osteosynthesis with good long-term results, obtaining an optimal union rate and low complications. In addition, it facilitates the reduction of the fracture, thus facilitating the patient's recovery and obtaining good long-term functional results. …”
Get full text

The Term ‘Ebda’ in the Comparative View of Fakhr Razi and Allameh Tabatabai by Mohammad Bahrami

“…However, they diverge in their methodologies: al-Razi predominantly uses Quranic verses, while Tabatabai incorporates both rational and scriptural proofs. Additionally, while al-Razi emphasizes the non-material aspects of creation, Tabatabai extends Ebda to all creations, including human actions.The study reveals a shared understanding of Ebda as dependent on God’s will, reflecting a common theological stance. …”
Get full text

Personalized approach in the management of women with heart failure with preserved ejection fraction and carbohydrate metabolism disorders by L.R. Petrovska, I.O. Kostitska, T.R. Petrovskyy, R.V. Petrovskyy

“…When using the studied treatments in individuals with HFpEF and prediabetes, it was confirmed a reliable normalization of glycemic control and a high chance (odds ratio 0.12, 95% confidence interval 0.011–1.339) of preventing the risk of T2DM. …”
Get full text

The Role of Potassium Phosphite in Enhancing the Activity of Defense Enzymes in Rice Infected by Sheath Blight by Milad Habibi Daronkolaei, Mohammad Ali Tajick Ghanbary, Valiollah Babaeizad, Heshmatollah Rahimian, Ali Dehestani

“…The severity of the disease was more pronounced in the control plants than in the plants treated with potassium phosphite, and in the sensitive variety (Khazar) than in the resistant variety (Tarom). Additionally, in both the control and treated plants, the disease progressed more by the 10th day after infection than on the 21st day. …”
Get full text

Ophthalmological monitoring in patients with hypertension and coronary heart disease by L.K. Moshetova, I.V. Vorobyeva, A. Dgebuadze, O.D. Ostroumova, A.V. Arablinskiy, E.P. Delver, A.A. Belogurov

“…Russian Journal of Clinical Ophthalmology. 2021;21(2):51–57. DOI: 10.32364/2311-7729-2021-21-2-51-57.</i> </p>…”
Get full text

Crystal structure and elastic properties of parabreyite: a new high-pressure ring silicate in the CaSiO₃ system by B. Chrappan Soldavini, M. Merlini, M. Gemmi, P. Parlanti, P. Fumagalli, S. Milani, B. Joseph, G. Bais, M. Polentarutti, A. Kurnosov, S. Poli

“…Thermal expansion was also determined by low- and high-temperature SC-XRD measurements and resulted in a larger value compared to breyite. Additionally, we performed in situ synchrotron SC-XRD on synthetic pseudowollastonite in the pressure interval 0–14 GPa and did not observe any structural phase transition in this ring-type polymorph. …”
Get full text

Effects of auricular acupoint pressing combined with modified Wendan decoction in the treatment of essential hypertension and accompanying insomnia (耳穴压豆联合加味温胆汤口服治疗原发性高血压伴失眠的效果观察)... by ZHAO Liyun (赵丽云), LIU Qing (刘青), LI Yigen (李乙根), XU Wenwei (徐文伟)

“…In the control group, patients received conventional antihypertensive drug therapy and standard nursing care; In the observation group, in addition to receiving the same standard treatment as the control group, patients also received auricular acupoint pressing therapy and oral treatment with modified Wenpan decoction. …”
Get full text

Key experimental technologies and their development directions for the exploration and production of deep coalbed methane by Xia YAN, Fengyin XU, Xianyue XIONG, Feng WANG, Chunhu LI, Jiyuan ZHANG, Borui XU, Qianhui CHENG, Xiong HU, Xueguang ZHU, Wei LIANG, Pu YUAN, Yanqing FENG, Zhenji WEI

“…ObjectiveDeep coalbed methane (CBM) production enjoys advantages including rapid gas shows, high single-well yield, and continuous resource distribution, which establish deep CBM as a significant target for reserve growth and production addition of natural gas. However, the exploration and production of deep CBM are still confronted with many technical challenges, and there is a lack of studies on key experimental technologies related to the geological characteristics and engineering assessment of deep CBM reservoirs, the occurrence characteristics and production mechanisms of gas and water, the formulation of production systems, and methods for enhanced CBM recovery. …”
Get full text