Lifetime history of concussion among children and adolescents with attention-deficit/hyperactivity disorder: examining differences stratified by age, medication status, and parent-... by Julia E. Maietta, Julia E. Maietta, Julia E. Maietta, Grant L. Iverson, Grant L. Iverson, Grant L. Iverson, Grant L. Iverson, Nathan E. Cook, Nathan E. Cook, Nathan E. Cook, Nathan E. Cook

“…A Mantel–Haenszel analysis was used to assess the associations between ADHD and lifetime concussion history across five age groups (ages 5–7, 8–10, 11–13, 14–15, and 16–17). Additional Mantel–Haenszel analyses were used to assess the associations between lifetime history of concussion and ADHD severity as well as medication status across five age groups.ResultsOverall, 6.2% of youth had a parent-reported history of concussion and 12.3% had parent-reported current ADHD. …”
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Supplementation of astaxanthin and vitamin E in feed on the development of gonads white shrimp broodstock Litopenaeus vannamei Boone 1931 by Fajar Maulana, Harton Arfah, Mita Istifarini, Mia Setiawati

“…ABSTRACT   The quality of white shrimp Litopenaeus vannamei broodstock can be improved through the addition of astaxanthin and vitamin E in the diet. …”
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Therapeutic Potential of Social Chatbots in Alleviating Loneliness and Social Anxiety: Quasi-Experimental Mixed Methods Study by Myungsung Kim, Seonmi Lee, Sieun Kim, Jeong-in Heo, Sangil Lee, Yu-Bin Shin, Chul-Hyun Cho, Dooyoung Jung

“…These findings indicate higher baseline loneliness, lower self-disclosure to the chatbot, and higher resilience significantly predicted higher loneliness at week 4. Additionally, higher baseline social anxiety significantly predicted higher social anxiety at week 4. …”
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Effects of Microbial Fertilizer Application on Soil Ecology in Saline–Alkali Fields by Xingguo Tian, Xiu Zhang, Guoping Yang, Yu Wang, Qianru Liu, Jingjing Song

“…The results indicated that, compared to NS0 and NS2 (the initial sowing period without microbial fertilizer addition), the soil pH and electrical conductivity (EC) levels significantly decreased by 4.1% and 8.49% and 60.56% and 39.66% for NS1 (after the first harvest) and NS3 (after the second harvest), respectively. …”
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Neuronal cell type specific roles for Nprl2 in neurodevelopmental disorder-relevant behaviors by Brianne Dentel, Lidiette Angeles-Perez, Abigail Y. Flores, Katherine Lei, Chongyu Ren, Andrea Pineda Sanchez, Peter T. Tsai

“…In contrast, deleting Nprl2 from inhibitory neurons led to increased motor learning, hyperactive behavior, in addition to social and learning deficits. Lastly, Purkinje cell (PC) loss of Nprl2 also led to learning and social deficits but did not affect locomotor activity. …”
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Adaptation for Staphylococcus aureus to hosts via insertion mutation in the accessory gene regulator agrC gene: decreased virulence and enhanced persistence capacity by Jiawei Chen, Yun Wu, Ying Zhu, Li Zhang, Yingchun Xu, Yali Liu

“…This mutated strain warrants clinical attention because it may lead to treatment failures and persist in patients.IMPORTANCEIn clinical antimicrobial therapy, bacterial strains often develop resistance to antimicrobial agents. Additionally, mutations in their gene regulatory networks can increase their persistence, especially in immunocompromised patients. …”
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Exploring the alleviating effects of Bifidobacterium metabolite lactic acid on non-alcoholic steatohepatitis through the gut-liver axis by Hongmei Zhao, Hongmei Zhao, Juan Zhou, Lingzhi Yuan, Zhiyi Sun, Yi Liu, Xinyu Zhao, Feng Ye

“…The evaluation of liver function and lipid metabolism was conducted using the liver-to-body weight ratio, histological staining, and biochemical assays. …”
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Performance of antiretroviral drugs supply chain management and related challenges in Amhara National Regional State, Ethiopia. In the case of public health facilities found in the... by Meseret Tilahun Zeleke, Berhanemeskel Weldegerima Atsbeha, Belachew Yebeyin Melaku, Yesuneh Tefera Mekasha, Abibo Wondie Mekonen, Shimelis Dagnachew Nigatu

“…Conclusion: Overall, the study indicated that the surveyed health facilities were not satisfied with the timely updating of bin cards. Additionally, it identified issues such as stock outs of ARV drugs, poor storage conditions (particularly in health centers), inadequate infrastructure, a shortage of trained and qualified staff, and a lack of vehicles. …”
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PIK3CA mutational status in tissue and plasma as a prognostic biomarker in HR+/HER2− breast cancer by Eduardo Terán, Rebeca Lozano, César A. Rodríguez, Mar Abad, Luis Figuero, José Antonio Muñoz, Belén Cigarral, Aline Rodrígues, Magdalena Sancho, M. Asunción Gómez, Daniel Morchón, Juan Carlos Montero, José María Sayagués, M. Dolores Ludeña, Emilio Fonseca

“…Conclusions Our findings suggest the PIK3CA evaluation in tissue as the diagnostic method of choice, however, additional investigations are required to improve the role of liquid biopsy in the PIK3CA assessment. …”
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Mark loss can strongly bias estimates of demographic rates in multi-state models: a case study with simulated and empirical datasets by Touzalin, Frédéric, Petit, Eric J., Cam, Emmanuelle, Stagier, Claire, Teeling, Emma C., Puechmaille, Sébastien J.

“…We assessed parameter bias by simulating a metapopulation system with varying capture and survival rates. Additionally, we demonstrated how mark loss can be easily estimated and accounted for using a 10-year empirical CMR dataset of bats. …”
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Prevalence of carbapenemase-encoding genes carriage in patients admitted to multidisciplinary hospital in Moscow by Ni O.G., Shifman E.M., Yakovlev S.V., Bykov A.O., Gorbacheva A.A., Kruglov A.N., Belotserkovskiy B.Z., Matyushkov N.S., Galata A.A., Protsenko D.N.

“…Rectal swab and oropharyngeal swab were collected from each patient. Additional lower respiratory tract samples were collected from patients who were undergoing mechanical ventilation. …”
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Characterization of the colostrum proteome of primiparous Holstein cows and its association with colostrum immunoglobulin G concentrations by Ezequias Castillo-Lopez, Patrick Biber, Arife Sener-Aydemir, Karin Hummel, Ebrahim Razzazi-Fazeli, Nicole Reisinger, Qendrim Zebeli, Susanne Kreuzer-Redmer, Thomas Hartinger

“…This resulted in enrichment of the biological processes predominantly for complement activation alternative pathway, complement activation, complement activation classical pathway, humoral immune response, leukocyte mediated immunity, and negative regulation of endopeptidase activity in excellent-quality colostrum. Additionally, some colostrum proteins were found to be correlated with the blood globulin level of cows and with the passive immunity level of calves (P < 0.05; r ≥ 0.57). …”
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Hubungan Antara Cache, Energy Consumption dan Runtime Performance pada Progressive Web Apps by Wakhid Kurniawan, Agung Fatwanto

“…Progresive Web Apps merupakan teknologi mutakhir di pengembangan web. Kehadiran Progresive Web Apps memberikan dampak positif bagi pengembang Web, yang mana keunggulannya memberikan peningkatan performa secara signifikan. …”
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Polysaccharides of Atractylodes Macrocephala Koidz Alleviate LPS-Induced Bursa of Fabricius Injury in Goslings by Inhibiting EREG Expression by Shuying Gong, Bingqi Zhang, Xiang Sun, Weijun Liang, Longsheng Hong, Xiang Zhou, Wanyan Li, Yunbo Tian, Danning Xu, Zhongping Wu, Bingxin Li

“…Further research showed that the addition of PAMKs significantly inhibited the LPS-induced EREG expression, increased the cell viability, promoted the cell cycle entry into the S and G2 phases, and inhibited apoptosis. …”
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Chemical Synthesis, Efficacy, and Safety of Antimalarial Hybrid Drug Comprising of Sarcosine and Aniline Pharmacophores as Scaffolds by Jean Baptiste Niyibizi, Peter G. Kirira, Francis T. Kimani, Fiona Oyatsi, Joseph K. Ng’ang’a

“…Currently, there is no effective vaccine for malaria control. In addition, although there are effective drugs for treatment of malaria, this could be lost to the drug resistance in different Plasmodium species. …”
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Synthesizing field plot and airborne remote sensing data to enhance national forest inventory mapping in the boreal forest of Interior Alaska by Pratima Khatri-Chhetri, Hans-Erik Andersen, Bruce Cook, Sean M. Hendryx, Liz van Wagtendonk, Van R. Kane

“…Among the various topographic factors, we found that elevation was the most important factor for discriminating all forest types. In addition, we found that canopy height and vegetation indices including Photochemical Reflectance Index (PRI) (R531 &amp; R570), Pigment Specific Normalized Difference (PSND) (R635 &amp; R800), and Gitelson and Merzlyak (GM1) (R550 &amp; R750) were important for differentiating between hardwood and softwood while Anthocyanin Reflectance Index (ARI1) (R550 &amp; R700) was important for differentiating between forest and nonforest. …”
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β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis by Yijia Zhang, Xinya Zhu, Liyuan Chen, Tianyu Gao, Guang Chen, Jin Zhu, Guoyu Wang, Daiying Zuo

“…Furthermore, the functional impact of TAM-derived OSM on PDAC progression was evaluated through in vitro co-culture systems and an in vivo Panc02 lung metastasis model. Additionally, mechanistic studies employed pharmacological inhibitors and genetic approaches targeting β-catenin, OSM, and STAT3 signaling.Notably, elevated expression of OSM and LOXL2 in PDAC specimens significantly correlated with poor patient survival. …”
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Growth, Development and Reproduction of Meadow Moth <i>Loxostege sticticalis</i> Fed on Pea Seedlings Grown Under Elevated CO₂ by Jingxian Zhou, Zun Xu, Zuoheng Yu, Huirong Mai, Jiacheng Huang, Xiaoli Chang, Fajun Chen

“…Host pea seedlings grown under eCO₂ exhibited significant increases in soluble sugar (SS), soluble protein (SP) and total amino acid (TAA) contents by 42.52%, 77.06% and 62.50%, respectively, relative to those grown under aCO₂. In addition, total phenol (TP), ethylene (ET) and jasmonic acid (JA) contents grown under eCO₂ increased significantly by 20.60%, 71.72% and 36.22%, respectively, under eCO₂ compared to aCO₂. …”
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3D-QSAR, design, molecular docking and dynamics simulation studies of novel 6-hydroxybenzothiazole-2-carboxamides as potentially potent and selective monoamine oxidase B inhibitors by Dong Xie, Dong Xie, Yongzheng Tian, Li Cao, Penghang Guo, Penghang Guo, Zhibiao Cai, Jie Zhou

“…MD simulation results showed that compound 31.j3 was stable in binding to the MAO-B receptor, and the RMSD values fluctuated between 1.0 and 2.0 Å, indicating its conformational stability. In addition, energy decomposition analysis revealed the contribution of key amino acid residues to the binding energy, especially Van der Waals interactions and electrostatic interactions play an important role in stabilizing the complex.ConclusionIn this study, the potential of 6-hydroxybenzothiazole-2-carboxamide derivatives as MAO-B inhibitors was systematically investigated by 3D-QSAR, molecular docking and MD simulations. …”
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Research on carbon emission accounting model for open-pit mines in alpine ecologically fragile areas by Guoqing LI, Bin BAI, Guiqi LI, Kai GUAN, Jie HOU, Chunping LIN

“…The energy-intensive nature of mining, along with the substantial transportation requirements over challenging terrains, significantly contributes to the carbon footprint. Additionally, beneficiation processes involving the separation and refinement of raw materials are highly energy-consuming, increasing indirect emissions. …”
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