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66481
Overexpression of miR-21-5p as a potential pathogenesis marker for ovarian endometriosis
Published 2025-01-01“…In this study, we screened the expression levels of 11-selected miRNAs, namely miR-21-5p, miR-200c-3p, miR-19a-3p, miR-203-3p, miR-181b-5p, miR-182-5p, miR-let7a-5p, miR-205-5p, miR-200b-3p, miR-16-5p, and miR-222-3p in ovarian endometriomas relative to eutopic endometrial tissues using quantitative real-time PCR (qPCR). In addition, the level of mRNA expression of lumican (LUM), an extracellular matrix proteoglycan (PG), and a putative target of miR-21-5p was quantified by qPCR. …”
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66482
Eicosapentaenoic Acid and Docosahexaenoic Acid as an Antimicrobial Agent in Orthopedics—An In Vitro Study About the Race for Surface
Published 2025-01-01“…After establishing the co-culture, cell culture and biofilm, we performed colony-forming unit counting and cell counting to examine cell survivability. In addition, we carried out scanning electron microscopy to study the race for surface behaviour of the cells. …”
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66483
Kinetic Analysis of the Reduction Processes of a Cisplatin Pt(IV) Prodrug by Mesna, Thioglycolic Acid, and Thiolactic Acid
Published 2020-01-01“…The species versus pH and reactivity of species versus pH distribution diagrams were constructed, demonstrating that the species ‒SCH2CH2SO3‒ of Mesna largely governs the total reactivity when pH > 5; in contrast, the form of Mesna per se (mainly as HSCH2CH2SO3‒) makes a negligible contribution. In addition, a well-determined dissociation constant for the Mesna thiol group (pKa2 = 8.85 ± 0.05 at 25.0°C and μ = 1.0 M) is offered in this work, which was determined by both kinetic approach and spectrophotometic titration method.…”
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66484
Unity in diversity: navigating global connections through cultural exchange
Published 2025-01-01“…Future studies could incorporate interviews and surveys to gain first-hand perspectives. In addition, the geographic focus on documented globalization effects limits broader applicability; more inclusive case studies across diverse cultural contexts are recommended. …”
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66485
Failure of Value Co-creation; Co-destruction of Brand Value in Social Media
Published 2024-06-01“…The application of the Dematel-ISM technique revealed that "poor customer relationship management" emerged as the most influential variable, while "negative interactions" was identified as the most affected variable. Additionally, "conflict in co-creating brand value management" stood out as the most relevant variable among others in the analysis. …”
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66486
The Language-Learning Potential of Writing for Learners of Spanish: Languaging and Task Complexity in Foreign Language Writing
Published 2019-12-01“…The keystroke-logging software Inputlog was also used to gather process data about the writers' behavior to solve the LREs. In addition, students were asked to complete a questionnaire to gauge their perception of task complexity. …”
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66487
Effect of Planting Systems on the Physicochemical Properties and Bioactivities of Strawberry Polysaccharides
Published 2025-01-01“…A higher extraction yield was observed for EP-SP (5.88%) than for GP-SP (4.67%), and slightly higher values were measured for the average molecular weight (632.10 kDa vs. 611.88 kDa) and total sugar content (39.38% vs. 34.92%) in EP-SP. …”
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66488
Incidence and predictors of seizure-related injuries among epileptic patients undergoing follow-up treatment at public hospitals in Central Ethiopia
Published 2025-01-01“…Risk factors identified included experiencing generalized tonic–clonic seizures, having at least one additional health condition, being on multiple medications, and consuming alcohol. …”
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66489
Dynamic selectout and voting-based federated learning for enhanced medical image analysis
Published 2025-01-01“…Based on how much their local performance has improved from the last communication cycle, we arbitrarily remove clients. Additionally eliminated are clients whose model weights when combined with the global model adversely affect its performance. …”
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66490
Penerapan Animasi 3D pada Media Pembelajaran Mengenal Huruf Vocal untuk Anak 2-4 Tahun
Published 2020-12-01“…This makes the child easily saturated and uninterested. In addition there is no media learning in the form of 3D animation. …”
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66491
Clinical Significance of Negative Costimulatory Molecule PD-1/PD-L1 on Peripheral Blood Regulatory T Cell Levels among Patients with Pulmonary Tuberculosis
Published 2022-01-01“…The PD-1 (6.13% ± 3.53% vs. 24.78% ± 7.73%, P<0.05) and PD-L1 levels (2.97% ± 2.00% vs. 9.23% ± 5.76%, P<0.05) were lower on peripheral blood CD4+CD25+CD127low Tregs among the TB group than in the control group. In addition, Pearson correlation analysis revealed a positive correlation between PD-1 and PD-L1 expression on peripheral blood CD4+CD25+CD127low Tregs among patients with active pulmonary TB (r = 0.435, P=0.016) and a negative correlation between the proportion of peripheral blood CD4+CD25+CD127low Tregs and PD-1 (r = ‒0.344, P=0.024) and PD-L1 expression among patients with active pulmonary TB (r = ‒0.310, P=0.043). …”
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66492
Developing a Prototype Machine Learning Model to Predict Quality of Life Measures in People Living With HIV
Published 2025-01-01“…R² = 0.698), reflecting variability in model accuracy across instruments. Additionally, the model demonstrated strong reliability in maintaining standardized prediction errors below 0.2 for most instruments, with probabilities of achieving this threshold being 96.43% for WHOQoL HIV Bref and 88.44% for ESTAR, while lower probabilities were observed for TSQM (44%) and WRFQ (51%).Conclusion: The results from our machine learning algorithms are promising for predicting PROMs and PREMs in AIDS settings. …”
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66493
Unveiling and validating biomarkers related to the IL-10 family in chronic sinusitis with nasal polyps: insights from transcriptomics and single-cell RNA sequencing analysis
Published 2025-01-01“…A competing endogenous RNA (ceRNA) network and a biomarker-drug interaction network were also established. Additionally, the mRNALocater database was utilized to determine the cellular localization of the identified biomarkers.ResultsThe intersection of 1817 DEGsall and 24 DEGsNP yielded 15 candidate genes. …”
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66494
CD28 Genetic Variants Increase Susceptibility to Diabetic Kidney Disease in Chinese Patients with Type 2 Diabetes: A Cross-Sectional Case Control Study
Published 2021-01-01“…Under additive genetic models, CD28-rs3116494 (OR=1.29 [95% CI 1.11, 1.51], P=0.0011) and CD80-rs3850890 (OR=1.16 [95% CI 1.02, 1.31], P=0.0283) were associated with DKD susceptibility adjusted for age, gender, body mass index (BMI), duration of diabetes, and HbA1c. …”
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66495
Thermodynamic Assessment of Different Feedstocks Gasification Using Supercritical Water and CO<sub>2</sub> for Hydrogen and Methane Production
Published 2025-01-01“…The impact of pressure change on the equilibrium compositions was not as significant as the effect observed by varying temperature; this behavior was observed in both gasification processes studied. Additionally, the behavior of the H<sub>2</sub>/CO molar ratio for each biomass in the studied gasification processes was analyzed to assess the potential uses of the produced syngas. …”
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66496
ON THE THIN PRACTICAL RATIONALITY AND ITS THICKENINGS
Published 1998-01-01“…Relatively practically rational is the choice of an agent whose preferences in addition to the standard 6 axioms of the theory of expected utility satisfy two supplementary ones: (7) preferences are realistic and (8) they are shaped in some specific way. …”
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66497
Study on the impact of Kinesiophobia after Total Knee Arthroplasty on the rehabilitation of patients during hospitalization: A pilot study.
Published 2025-01-01“…Patients in the kinesiophobia group delayed getting out of bed for the first time (35.39±9.82vs28.77±9.81hours; P<0.01), had shorter activity time (4.12±1.36vs5.80±1.96minutes; P<0.01) and distance (19.12±3.36vs30.17±5.64meters;P<0.01), and experienced higher pain scores during activity (6.30±1.10vs5.48±0.95scoresP<0.05). Additionally, patients in the kinesiophobia group walked shorter distances in the 2-MWT test on the day of discharge compared to the non-kinesiophobia group (37.60±5.76vs50.68±5.37meters;P<0.05), and had longer hospitalization time (8.11±1.31vs50.68±5.37days; P<0.05). …”
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66498
Assessment of upper respiratory and gut bacterial microbiomes during COVID-19 infection in adults: potential aerodigestive transmission
Published 2025-01-01“…The presence of increased RSI scores, combined with elevated levels of Pepsin, suggests that increased micro-aspiration may occur, which is consistent with of under-recognized interactions between the GI and lung microbiomes in COVID-19 patients and requires additional study. Such studies would benefit from the insights provided by biological samples which reflect the continuum of the aerodigestive tract.…”
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66499
Optimization design of an acoustic cover layer for a cylindrical cavity based on porous materials
Published 2025-03-01“…However, increasing the coverage rate of the porous material did not lead to proportional improvements in noise reduction or vibration damping. …”
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66500
Parejas heterosexuales serodiscordantes en Chiapas, México. La influencia del género en la expresión de la agencia/Heterosexual HIV-Discordant Couples in Chiapas, Mexico. The Influ...
Published 2019-06-01“…They had more difficulties than the two men, in their eagerness to maintain a stable couple relationship. In addition, they were exposed to risks of unwanted pregnancy and violence, for hiding the diagnosis. …”
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