Early warning systems for identifying severe maternal outcomes: findings from the WHO global maternal sepsis studyResearch in context by Yamikani Chimwaza, Alexandra Hunt, Livia Oliveira-Ciabati, Laura Bonnett, Edgardo Abalos, Cristina Cuesta, João Paulo Souza, Mercedes Bonet, Vanessa Brizuela, David Lissauer, Yamikani Chimwaza, Alexandra Hunt, Livia Oliveira-Ciabati, Laura Bonnett, Edgardo Abalos, Cristina Cuesta, João Paulo Souza, Mercedes Bonet, Vanessa Brizuela, David Lissauer, Mohammad Iqbal Aman, Bashir Noormal, Marisa Espinoza, Julia Pasquale, Charlotte Leroy, Kristien Roelens, Griet Vandenberghe, M. Christian Urlyss Agossou, Sourou Goufodji Keke, Christiane Tshabu Aguemon, Patricia Soledad Apaza Peralta, Víctor Conde Altamirano, Rosalinda Hernández Muñoz, José Guilherme Cecatti, Carolina Ribeiro do Valle, Vincent Batiene, Kadari Cisse, Henri Gautier Ouedraogo, Kannitha Cheang, Phirun Lam, Tung Rathavy, Elie Simo, Pierre-Marie Tebeu, Emah Irene Yakana, Javier Carvajal, María Fernanda Escobar, Paula Fernández, Lotte Berdiin Colmorn, Jens Langhoff-Roos, Wilson Mereci, Paola Vélez, Yasser Salah Eldin, Alaa Sultan, Alula M. Teklu, Dawit Worku, Richard Adanu, Philip Govule, Charles Noora Lwanga, William Enrique Arriaga Romero, María Guadalupe Flores Aceituno, Carolina Bustillo, Bredy Lara, Vijay Kumar, Vanita Suri, Sonia Trikha, Irene Cetin, Serena Donati, Carlo Personeni, Guldana Baimussanova, Saule Kabylova, Balgyn Sagyndykova, George Gwako, Alfred Osoti, Zahida Qureshi, Raisa Asylbasheva, Aigul Boobekova, Damira Seksenbaeva, Saad Eddine Itani, Meilė Minkauskienė, Diana Ramašauskaitė, Owen Chikhwaza, Luis Gadama, Eddie Malunga, Haoua Dembele, Hamadoun Sangho, Fanta Eliane Zerbo, Filiberto Dávila Serapio, Nazarea Herrera Maldonado, Juan I. Islas Castañeda, Tatiana Cauaus, Ala Curteanu, Victor Petrov, Yadamsuren Buyanjargal, Seded Khishgee, Bat-Erdene Lkhagvasuren, Amina Essolbi, Rachid Moulki, Zara Jaze, Arlete Mariano, Nafissa Bique Osman, Hla Mya Thway Einda, Thae Maung Maung, Khaing Nwe Tin, Tara Gurung, Amir Babu Shrestha, Sangeeta Shrestha, Kitty Bloemenkamp, Marcus J. Rijken, Thomas Van Den Akker, María Esther Estrada, Néstor J. Pavón Gómez, Olubukola Adesina, Chris Aimakhu, Bukola Fawole, Rizwana Chaudhri, Saima Hamid, M. Adnan Khan, María del Pilar Huatuco Hernández, Nelly M. Zavaleta Pimentel, Maria Lu Andal, Zenaida Dy Recidoro, Carolina Paula Martin, Mihaela Budianu, Lucian Pușcașiu, Léopold Diouf, Dembo Guirassy, Philippe Marc Moreira, Miroslav Borovsky, Ladislav Kovac, Alexandra Kristufkova, Sylvia Cebekhulu, Laura Cornelissen, Priya Soma-Pillay, Vicenç Cararach, Marta López, María José Vidal Benedé, Hemali Jayakody, Kapila Jayaratne, Dhammica Rowel, Wisal Nabag, Sara Omer, Victoria Tsoy, Urunbish Uzakova, Dilrabo Yunusova, Thitiporn Siriwachirachai, Thumwadee Tangsiriwatthana, Catherine Dunlop, Marian Knight, Jhon Roman, Gerardo Vitureira, Dinh Anh Tuan, Luong Ngoc Truong, Nghiem Thi Xuan Hanh, Mugove Madziyire, Thulani Magwali, Stephen Munjanja, Adama Baguiya, Mónica Chamillard, Bukola Fawole, Marian Knight, Seni Kouanda, Pisake Lumbiganon, Ashraf Nabhan, Ruta Nadisauskiene, Linda Bartlett, Fernando Bellissimo-Rodrigues, Shevin T. Jacob, Sadia Shakoor, Khalid Yunis, Liana Campodónico, Hugo Gamerro, Daniel Giordano, Fernando Althabe, A. Metin Gülmezoglu

“…Sensitivity, specificity, positive and negative likelihood ratios, diagnostic odds ratios, and J statistics were calculated to assess EWS performance. …”
Get full text

Expression‐based machine learning models for predicting plant tissue identity by Sourabh Palande, Jeremy Arsenault, Patricia Basurto‐Lozada, Andrew Bleich, Brianna N. I. Brown, Sophia F. Buysse, Noelle A. Connors, Sikta Das Adhikari, Kara C. Dobson, Francisco Xavier Guerra‐Castillo, Maria F. Guerrero‐Carrillo, Sophia Harlow, Héctor Herrera‐Orozco, Asia T. Hightower, Paulo Izquierdo, MacKenzie Jacobs, Nicholas A. Johnson, Wendy Leuenberger, Alessandro Lopez‐Hernandez, Alicia Luckie‐Duque, Camila Martínez‐Avila, Eddy J. Mendoza‐Galindo, David Cruz Plancarte, Jenny M. Schuster, Harry Shomer, Sidney C. Sitar, Anne K. Steensma, Joanne Elise Thomson, Damián Villaseñor‐Amador, Robin Waterman, Brandon M. Webster, Madison Whyte, Sofía Zorilla‐Azcué, Beronda L. Montgomery, Aman Y. Husbands, Arjun Krishnan, Sarah Percival, Elizabeth Munch, Robert VanBuren, Daniel H. Chitwood, Alejandra Rougon‐Cardoso

Get full text

Impact of COVID-19 pandemic restrictions and relaxation on pediatric respiratory virus hospitalizations in Southwest China: a retrospective study by Ting Gong, Fengqi He, Yongle Zhao, Shuya Lu, Daiyin Tian, Daiyin Tian

“…The significance of vaccination, hygiene practices, public health interventions and etc. was emphasized in addressing pandemics. Additionally, ongoing dynamic monitoring is essential due to the evolving epidemiology.…”
Get full text

Effects of Sewage Sludge Compost on Carbon, Nitrogen, Phosphorus, and Sulfur Ratios and Soil Enzyme Activities in a Long-Term Experiment by Csilla Almási, Viktória Orosz, Timea Tóth, Mostafa M. Mansour, Ibolya Demeter, István Henzsel, Zsolt Bogdányi, Tamás András Szegi, Marianna Makádi

“…We conclude that the addition of SSC could improve soil health through increasing the pH, OM, nutrient content, and microbial activity. …”
Get full text

Permafrost pore structure and its influence on microbial diversity: Insights from X-ray computed tomography by Nathan D. Blais, Joy M. O’Brien, Hannah Holland-Moritz, Lauren Farnsworth, Robyn A. Barbato, Thomas A. Douglas, Alexandra Contosta, Julie Bobyock, Erin C. Rooney, Taylor Sullivan, Jessica Gilman Ernakovich

“…For example, we found that pores in the range of 75–1000 µm are the dominant pore size class and a positive relationship between total porosity and pore connectivity. Additionally, we identified pore connectivity as a potential driver of microbial diversity and provided evidence that conditions before the formation of permafrost exert a strong legacy effect on currently observed permafrost microbial diversity. …”
Get full text

Whole-genome sequencing identifies novel loci for keratoconus and facilitates risk stratification in a Han Chinese population by Yinghao Yao, Xingyong Li, Lan Wu, Jia Zhang, Yuanyuan Gui, Xiangyi Yu, Yang Zhou, Xuefei Li, Xinyu Liu, Shilai Xing, Gang An, Zhenlin Du, Hui Liu, Shasha Li, Xiaoguang Yu, Myopia Associated Genetics Intervention and Consortiums, Hua Chen, Jianzhong Su, Shihao Chen

“…Our study validated three well known predisposition loci, COL5A1, EIF3A and FNDC3B. Additionally, a significant correlation of allelic effects was observed for suggestive SNPs between the largest multi-ethnic meta-genome-wide association study (GWAS) and our study. …”
Get full text

Compatibility and antimicrobial activity of silver nanoparticles synthesized using Lycopersicon esculentum peels by Esraa Ali, Samah H. Abu-Hussien, Esraa Hesham, Shimaa Ahmed, Habiba Mostafa, Ahmed Gamal, Salwa M. El-Sayed, Bahaa Hemdan, Ashraf Bakry, Naglaa M. Ebeed, Hesham Elhariry, Ahmed Galal, Basma T. Abd-Elhalim

“…The current study focused on the environmentally friendly synthesis of silver nanoparticles (AgNPs) using Lycopersicon esculentum peel. In addition to studying the intrinsic cytotoxic effectiveness of Le-AgNPs contribute to their antibacterial, and antifungal activities and the effect of nanoparticles on the integrity of their morphological behavior. …”
Get full text

Design of Command and Dispatch System for Automatic Reading of Meter Images in Substations by UAV Inspection Photos by Guanghong Deng, Liangpei Lin, Baihao Lin, Wenlong Jing, Xiaodan Zhao, Yong Li, Rui Yang, Shidun Xie, Pengfeng Wei

“…In order to solve the problem of inaccurate pointer meter readings, to begin with, the segmented image is corroded; in addition, the circular dial area is flattened into a rectangular area by concentric circle sampling method. …”
Get full text

The Positive Regulatory Effect of DBT on Lipid Metabolism in Postpartum Dairy Cows by Zheng Zhou, Kang Yong, Zhengzhong Luo, Zhenlong Du, Tao Zhou, Xiaoping Li, Xueping Yao, Liuhong Shen, Shumin Yu, Yixin Huang, Suizhong Cao

“…Results: Our research shows that, in dairy cows 7 days postpartum, DBT significantly reduced serum 3-hydroxybutyric acid (BHB) concentrations and the number of cows with BHB concentrations ≥ 1 mmol/L. Additionally, DBT increased serum total cholesterol contents at both 7 and 14 days postpartum. …”
Get full text

Incidence and prevalence of traumatic and non-traumatic wounds and burns and access to wound care in Sierra Leone; data from a nationwide household survey (PRESSCO) 2020 by Jonathan H. Vas Nunes, Alex J. van Duinen, Daniel Boateng, Amidu J. Tommy, Osman Sankoh, Martin P. Grobusch, Håkon A. Bolkan

“…The survey was based on Surgeons OverSeas Assessment of Surgical Need (SOSAS). Additional questions relating to wounds and burns were added. …”
Get full text

Associations of fasting plasma glucose and glycosylated hemoglobin levels at less than 24 weeks of gestation with hypertensive disorders of pregnancy: the BOSHI study by Seiya Izumi, Noriyuki Iwama, Hirotaka Hamada, Taku Obara, Mami Ishikuro, Michihiro Satoh, Takahisa Murakami, Masatoshi Saito, Takayoshi Ohkubo, Takashi Sugiyama, Shinichi Kuriyama, Nobuo Yaegashi, Kazuhiko Hoshi, Yutaka Imai, Hirohito Metoki, the BOSHI Study Group

“…When FPG and HbA1c were included in the model separately, quartile 4 (Q4) of FPG (87–125 mg/dL) and HbA1c (5.2–6.3% [33–45 mmol/mol]) levels had higher odds of HDP than quartile 1. The odds ratios (ORs) were 1.334 (95% confidence interval [CI]: 1.002–1.775) for Q4 of FPG and 1.405 (95% CI: 1.051–1.878) for Q4 of HbA1c. …”
Get full text

Identification of novel autoantibodies in Sjögren’s disease by Fiona Engelke, Petra Budde, Salvatore De Vita, Thomas Dörner, Diana Ernst, Jan Gras, Harald Heidecke, Annika Loredana Kilian, Katja Kniesch, Ann-Sophie Lindemann, Luca Quartuccio, Jacob Ritter, Kai Schulze-Forster, Benjamin Seeliger, Hans-Dieter Zucht, Torsten Witte

“…We have developed a three and five marker panel for the detection of Ro/SSA negative patients, consisting of anti-FNBP4, anti-SNRPC, anti-CCL4, anti-M3 and anti-KDM6B, which had a sensitivity of up to 46% with a specificity of 95% (SjD vs. …”
Get full text

Effectiveness and Safety of Treatments for Early‐Stage Merkel Cell Carcinoma: A Systematic Review and Meta‐Analysis of Randomized and Non‐Randomized Studies by Yves Paul Vincent Mbous, Rowida Mohamed, Usha Sambamoorthi, Murtuza Bharmal, Khalid M. Kamal, Traci LeMasters, Joanna Kolodney, George A. Kelley

“…The E‐value suggested that the RTx dose was a confounder of the observed effectiveness of adjuvant RTx; and also, the use of CTx following adjuvant RTx, did not impact the strength of evidence for OS. …”
Get full text

A preliminary study of linear accelerator-based spatially fractionated radiotherapy by Young Kyu Lee, Yunji Seol, Byeong Jin Kim, Kyu Hye Choi, Ji Hyun Hong, Chan-beom Park, Sun Hwa Kim, Hyeong Wook Park, Wonjoong Cheon, Young Nam Kang, Byung‑Ock Choi

“…Peak-to-valley dose ratio (PVDR) was calculated along three orthogonal axes, and normal tissue dose and monitor units (MU) were analyzed. Additionally, the modulation complexity score (MCS) was calculated for each plan to quantitatively assess treatment plan complexity.ResultsThe PVDR analysis demonstrated heterogeneous dose distribution, with optimal values below 30% in all directions for 5.0 cm separation. …”
Get full text

Loneliness and Social Isolation with Risk of Incident Non-alcoholic Fatty Liver Disease, UK Biobank 2006 to 2022 by Ya Miao, Xiaoke Kong, Bin Zhao, Fang Fang, Jin Chai, Jiaqi Huang

“…No significant multiplicative or additive interaction was found between loneliness and social isolation on the risk of NAFLD. …”
Get full text

Prognostic role of the pathological status following neoadjuvant chemoradiotherapy and surgery in esophageal squamous cell carcinoma by Xiaofeng Duan, Jie Yue, Shangren Wang, Fangdong Zhao, Wencheng Zhang, Shuo Qie, Hongjing Jiang

“…There were 39 (28.7%) patients with ypT0N0 disease, 49 (36.0%) ypT + N0, 11 (8.1%) ypT0N+, and 37 (27.2%) ypT + N+. Additionally, 126 patients had a median follow-up period of 30 (1–90) months. …”
Get full text

Assessment of vitamin D status in obese and non-obese patients: A case-control study by Salma Derbel, Lamiae Zarraa, Imane Assarrar, Nisrine Bouichrat, Siham Rouf, Hanane Latrech

“…In addition, the correlation between vitamin D, blood pressure, and body mass index was significant (p = 0.004) as well as between vitamin D and triglycerides (p = 0.015) and cholesterol (p = 0.014). …”
Get full text

Correlations among lymphocyte count, white matter hyperintensity and brain atrophy in patients with ischemic stroke by Chenchen Liu, Dai Shi, Xiaoqiong Ni, Shoujiang You, Shoujiang You, Xiaofen Wu, Sheng Zhuang, Sheng Zhuang, Wu Cai, Liang Xu, Liang Xu

“…After adjustment for potential covariates, the highest quartiles of lymphocyte counts were significantly associated with lower risk of WMH (adjusted odds ratio [aOR] 0.57, 95% confidence intervals [CI] 0.32–0.99), PVH (aOR 0.52, 95% CI 0.31–0.87), DWMH (aOR 0.53 95% CI 0.32–0.90) as well as brain atrophy (aOR 0.46, 95% CI 0.23–0.92) compared with the lowest quartiles of lymphocyte counts, respectively. …”
Get full text

Newly identified c-di-GMP pathway putative EAL domain gene STM0343 regulates stress resistance and virulence in Salmonella enterica serovar Typhimurium by Kaifeng Chen, Lili Li, Nanwei Wang, Zhouping Zhou, Peng Pan, Chenggang Xu, Dage Sun, Jiayi Li, Changzhi Dai, Dai Kuang, Ming Liao, Jianmin Zhang

Subjects: Get full text

Efficacy of the Bushen Jianpi Huoxue Formula on Beclin-1/Bcl-2-mediated autophagy and apoptosis in osteoblasts by Yanping Lin, Yanping Lin, Rui Zhao, Rui Zhao, Jiachun Huang, Tongying Chen, Tongying Chen, Haolin Yang, Haolin Yang, Haiwei Guo, Lei Wan, Zhihai Zhang, Ying Li, Genfu Zhu, Hongxing Huang, Hongxing Huang

“…This study first investigates whether the Bushen Jianpi Huoxue Formula can enhance the cellular function of osteoblasts. Additionally, it initially explores the functional mechanism of Beclin-1/Bcl-2-related apoptosis.MethodsOsteoblasts were isolated from the calvaria of three-day-old Sprague-Dawley female rats. …”
Get full text