Prevalence, cessation, and geographical variation of smoking among middle-aged and elderly adults in China: A population-based study by Qingjia Zeng, Chongyang Zhang, Feiyu Su, Yanli Wan, Wen-jun Tu, Hongpu Hu

“…Urban residents and those with advanced education had lower smoking rates and higher cessation rates. Additionally, the dose-response relationship indicated a more pronounced association between higher smoking pack-years and elevated health risks, including hypertension (aOR=1.30, 95% CI: 1.24-1.36), diabetes (aOR=1.26, 95% CI: 1.20-1.33), hyperlipidemia (aOR=1.22, 95% CI: 1.16-1.28), heart disease (aOR=1.40, 95% CI: 1.26-1.54), and stroke (aOR=1.23, 95% CI: 1.10-1.36). …”
Get full text

Epidemiological characteristics of stroke incidence from 2017 to 2022 in Songjiang District, Shanghai by SU Xuyan, WANG Yuzhuo, WU Yiling, HE Jingyi, YANG Peng, LANG Dongchen, JIANG Yonggen, ZHAO Genming, ZHENG Yang

“…ObjectiveTo investigate the prevalence of stroke in Songjiang District from 2017 to 2022, to analyze the epidemiological characteristics of stroke incidence, so as to provide a scientific basis for the formulation of stroke prevention and control policies.MethodsData of new stroke incidence from 2017 to 2022 in Songjiang District were obtained from the Shanghai Stroke and Acute Myocardial Infarction Registration and Reporting Information System. In addition, different classifications such as time of onset, gender, age group and types of stroke, were statistically analyzed. …”
Get full text

Assessment of genetic conservation units of an endangered glacial relict insular species, Amentotaxus formosana, based on fine-scale genetic structures of multiple fragmented mount... by Ya-Zhu Ko, Huie-Chuan Shih, Chin-Shang Ho, Chaur-Tzuhn Chen, Tsai-Wen Hsu, Meng-Shin Shiao, Yu-Chung Chiang, Yu-Chung Chiang

“…Results indicated low genetic diversity, distinct genetic differentiation, and severe inbreeding within fragmented populations. Additionally, demographic analysis suggested a substantial downfall in effective population sizes and limited gene flow within and between populations. …”
Get full text

Anti-arthritic potential of crude sulfated polysaccharide from marine macroalgae Sargassum ilicifolium (Turner) C. Agardh: Regulation of cytokine cascade by Ramamoorthi Lavanya, Jeyabalan Srikanth, Sankar Seethalakshmi, Begum M. Yasmin, Duraipandian Chamundeeswari, Sekar Mahendran, Wong Ling Shing, Subramaniyan Vetriselvan

“…The isolated and freeze-dried polysaccharide was tested for acute oral toxicity based on OECD 423. …”
Get full text

Long-term changes in the thermodynamic structure of the lowermost stratosphere inferred from reanalysis data by F. Weyland, P. Hoor, D. Kunkel, T. Birner, T. Birner, F. Plöger, F. Plöger, K. Turhal, K. Turhal

“…In the Northern Hemisphere (NH), we find that the extratropical tropopause is rising, accompanied by decreasing pressure at an average rate of <span class="inline-formula">−</span>1 <span class="inline-formula">hPa</span> per decade. Additionally, our results indicate that the tropical tropopause in the NH has expanded poleward by 0.5<span class="inline-formula">°</span> latitude between 1998–2019. …”
Get full text

Association of triglyceride glucose-related obesity indices with sarcopenia among U.S. adults: a cross-sectional study from the National Health and Nutrition Examination Survey by Runtao Zhao, Xinqiang Ji, Fan Wang

“…In the fully adjusted regression model, a positive correlation was observed between the TyG-WHtR index and sarcopenia (for each one-unit increase in TyG-WHtR index: OR = 3.57, 95% CI: 2.71–4.71, P < 0.001). Additionally, regression analyses demonstrated TyG-WHtR as a significant predictor of sarcopenia with the highest odds ratio, reaching 12.50 (95% CI: 6.13–25.70, P < 0.001) for the upper fourth quartile (Q4) compared to the first quartile, followed by followed by TyG-BMI (Q4: 3.34; 95% CI: 1.92–5.80, P < 0.001) and TyG-WC (Q4: 1.95; 95% CI: 1.04–3.68, P < 0.001). …”
Get full text

Intra-operative nasal compression after lateral osteotomy to minimize post-operative Peri-orbital ecchymosis and edema by L. Sowerby, L. M. Kim, W. Chow, C. Moore

“…Although the effect may be variable to some degree, this is an intervention with no additional risks involved and thus can be used in a safe manner.…”
Get full text

Respectful maternity care and associated factors among mothers who gave birth at public health institutions in Debre Tabor town, Northwest Ethiopia: a mixed-methods study by Tadesse Ayana Fentie, Abayneh Aklilu Solomon, Mihretu Molla Enyew, Meseret Mekuriaw Beyene, Ayalew Kassie Melese, Alamirew Enyew Belay, Gebrie Getu Alemu

“…A multivariable logistic regression analysis was performed to identify factors associated with the outcome variable. Adjusted odds ratios with 95% confidence intervals were computed to determine the significance level. …”
Get full text

Adaptive Hierarchical Multi-Headed Convolutional Neural Network With Modified Convolutional Block Attention for Aerial Forest Fire Detection by Md. Najmul Mowla, Davood Asadi, Shamsul Masum, Khaled Rabie

“…Compared to the baseline hierarchical MHCNN with CBAM (HMHCNN-CBAM), AHMHCNN-mCBAM demonstrated significant performance gains, including a 6.80% and 6.59% increase in accuracy, a 9.26% and 14.11% improvement in cKappa, and a 13.87% and 13.76% reduction in parameter size on the UAVs-FFDB and FLAME datasets, respectively. Additionally, AHMHCNN-mCBAM outperformed HMHCNN-CBAM in recall (25% improvement), precision (21.95%), F1-score (14.94%), and fire detection rate (FDR) reduction (25.01%), while achieving a 100% reduction in error warning rate (EWR). …”
Get full text

Evaluation of an interprofessional education program involving medical and pharmacy students: a mixed-method study by Josephine F. Mertens, Marleen H. M. Hessel, Thomas G. H. Kempen, Stefan Böhringer, Adriaan F. Norbart, Chris W. Walinga, Teun van Gelder

“…Semi-structured interviews provided additional qualitative insights, which were analyzed using thematic analysis. …”
Get full text

Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction by Jingrun Lin, Xiaoqiu Zhu, Xuan Li, Yu Hong, Yaohui Liang, Siqi Chen, Chenzhuo Feng, Lin Cao

“…We identified several key lncRNAs and miRNAs implicated in neurogenesis regulation. Additionally, drugs were predicted as potential therapeutic candidates for POCD treatment. …”
Get full text

Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice by Yan Yang, Wenting Zhang, Xiaohui Wu, Jing Wu, Chengjun Sun, Feihong Luo, Zhou Pei

“…Hence, our study suggests that the management of NAFLD should be targeted to reduce the overall amount of body fat and improve metabolic status before the progression to nonalcoholic steatohepatitis occurs.…”
Get full text

US-guided high-intensity focused ultrasound in pancreatic cancer treatment: a consensus initiative between Chinese and European HIFU centers by Kun Zhou, Holger Strunk, Dobromir Dimitrov, Joan Vidal-Jove, Maria A. Gonzalez-Carmona, Markus Essler, Chengbin Jin, Zhechuan Mei, Hui Zhu, Milka Marinova

“…This treatment method significantly alleviates disease-related symptoms and reduces pancreatic tumor volume. However, the current body of evidence is constrained by a lack of randomized controlled trials. …”
Get full text

Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism by Yang Yang, Yang Yang, Qing Hong, Qing Hong, Xuehong Zhang, Zhenmin Liu, Zhenmin Liu

“…Alterations in gut microbiota and metabolites were assessed by 16S rDNA and non-targeted metabolomics.ResultsThe findings reveal that administering Bifidobacterium animalis BD400 orally led to a significant reduction in arthritis clinical scores and paw swelling thickness in CIA rats. Additionally, there was a decrease in osteo-facial fusion and calcified cartilage thickening in the knee joint. …”
Get full text

The genetic duet of concurrent RASAL1 and PTEN alterations promotes cancer aggressiveness by cooperatively activating the PI3K–AKT pathway by Xiaopei Shen, Jie Tan, Rengyun Liu, Guangwu Zhu, Lisa Rooper, Mingzhao Xing

“…This was enhanced by additional tumor protein p53 (TP53) gene alterations, with cancer progression and mortality rates being 47.65% and 34.46% with coexisting RASAL1, PTEN, and TP53 alterations versus 25.30% and 13.11% with no alteration (HR 2.21, 95% CI 1.92–2.56 and 2.76, 95% CI 2.31–3.30), respectively. …”
Get full text

A User-Centered Design Approach for a Screening App for People With Cognitive Impairment (digiDEM-SCREEN): Development and Usability Study by Michael Zeiler, Nikolas Dietzel, Fabian Haug, Julian Haug, Klaus Kammerer, Rüdiger Pryss, Peter Heuschmann, Elmar Graessel, Peter L Kolominsky-Rabas, Hans-Ulrich Prokosch

“…The texts were also adapted to the German-speaking context. Additional instructions were developed and supplemented. …”
Get full text

Psychological well-being and academic performance of Ukrainian medical students under the burden of war: a cross-sectional study by Mykhaylo Korda, Arkadii Shulhai, Oksana Shevchuk, Oleksandra Shulhai, Anna-Mariia Shulhai, Anna-Mariia Shulhai

“…Severe and extremely severe depressive symptoms were observed in 25.6% of students, anxiety in 31.9%, and stress in 29.7%, with a higher prevalence among female students. Additionally, 44.2% of responders had significant symptoms of post-traumatic stress disorder, with the highest scores on the hyperarousal subscale (&gt;37). …”
Get full text

The mediating effect of the budget process on the performance of small- and medium-sized enterprises in Ho Chi Minh City, Vietnam by Vuong Khanh Tuan, Premkumar Rajagopal

“…This research model can be applied to management practices to restructure, innovate, and improve the overall performance of SMEs. Additionally, this study will provide SMEs with management procedures to compete, adapt, and enhance their sustainability within the global market. …”
Get full text

Lactobacillus fermentum B153 from human colostrum modulates intestinal immunity and gut microbiota in obese mice model by Juqing Huang, Xiaohui Cai, Xiaoyan Liu, Gongti Lai, Xuefang Guan, Bingyan Chen, Qi Wang

Get full text

The impact of Covid-19 on harm reduction policies in Iran: an interrupted time series analysis by Siavash Beiranvand, Meysam Behzadifar, Aidin Aryankhesal, Seyed Jafar Ehsanzadeh, Masoud Behzadifar

“…Methadone dispensation, crucial for opioid harm reduction, also witnessed a substantial level change, decreasing by 5,007.60 cc per month (95% CI: -6,251.75 to -3,763.45). Additionally, the provision of syringes decreased significantly, with a level change of -601.01 units per month (95% CI: -706.39 to -495.62). …”
Get full text