Inhibition of programmed cell death by melanoma cell subpopulations reveals mechanisms of melanoma metastasis and potential therapeutic targets by Yuepeng An, Fu Zhao, Hongling Jia, Siyu Meng, Ziwei Zhang, Shuxiao Li, Jiusi Zhao

“…Our findings revealed a close relationship between the pivotal C0 SOD3 + Melanoma cells subpopulation and oxidative pathways in metastatic tumor tissues. Additionally, we analyzed prognostically relevant differentially expressed genes (DEGs) within the C0 SOD3 + Melanoma cells subpopulation and built a predictive model associated with melanoma outcomes. …”
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An approach to boost adherence to self-data reporting in mHealth applications for users without specific health conditions by Maria Aguiar, Ander Cejudo, Gorka Epelde, Deisy Chaves, Maria Trujillo, Garazi Artola, Unai Ayala, Roberto Bilbao, Itziar Tueros

“…Conclusion This study evidences the effectiveness of the gamification category of behavior change techniques in increasing the overall user adherence, expectations, and perceived usability. In addition, the results provide quantitative results on the effect of the most common categories of behavior change techniques for the self-report of lifestyle data. …”
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Pharmacogenomics predictors of aromatic antiepileptic drugs-induced SCARs in the Iraqi patients by Ali Fadhel Ahmed, Dzul Azri Mohamed Noor, Majeed Arsheed Sabbah, Nur Fadhlina Musa, Nur Aizati Athirah Daud

“…For AED-induced TEN, HLA-A∗01:02, HLA-B∗15:02, and HLA-B∗52:01 showed significant associations (OR = 6.92; 95 % CI: 1.39–34.37 and OR = 6.55; 95 % CI: 1.62–26.52, respectively), with HLA-DRB1∗03:01 being highly significant (OR = 5.09; 95 % CI: 1.72–15.00). Additionally, HLA-B∗40:02 was strongly associated with AED-induced DRESS (OR = 29.33; 95 % CI: 3.50–245.32). …”
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Systematic review of amyloid-beta clearance proteins from the brain to the periphery: implications for Alzheimer’s disease diagnosis and therapeutic targets by Letian Huang, Mingyue Liu, Ze Li, Bing Li, Jiahe Wang, Ke Zhang

“…The inclusion criteria included studies comparing the levels of functional proteins associated with amyloid-beta clearance in the blood, cerebrospinal fluid, and brain of healthy controls, patients with mild cognitive impairment, and patients with Alzheimer’s disease. Additionally, we analyzed the correlation between these functional proteins and amyloid-beta levels in patients with Alzheimer’s disease. …”
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Air Quality Index, Indicatory Air Pollutants and Impact of COVID-19 Event on the Air Quality near Central China by Kaijie Xu, Kangping Cui, Li-Hao Young, Ya-Fen Wang, Yen-Kung Hsieh, Shun Wan, Jiajia Zhang

“…However, the O3 average concentration (80.6 ppb) did not show significant fluctuations and even slightly increased by 3.6%. …”
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Capturing the extent of climate's dynamic effects on runoff and nutrient yields across short- and long-term scales by Di Chang, Shuo Li

“…For coupled effects, long–term temperature variation suppressed precipitation's promotion on runoff and TP outputs but enhanced its impact on TN outputs. Additionally, wind speed and radiation amplified precipitation's effects. …”
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The Electroanatomic Volume of the Left Atrium as a Determinant of Recurrences in Patients with Atrial Fibrillation After Pulmonary Vein Isolation: A Prospective Study by Amaia Martínez León, David Testa Alonso, María Salgado, Ruth Álvarez Velasco, Minel Soroa, Daniel Gracia Iglesias, David Calvo

“…In patients selected for catheter ablation, EAV by EAM provides additional insights that could contribute to therapeutic decision-making and risk stratification of AF recurrences.…”
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Risk of Dysglycemia in Pregnancy amongst Kenyan Women with HIV Infection: A Nested Case-Control Analysis from the STRiDE Study by Sonak D. Pastakia, Wycliffe K. Kosgei, Astrid Christoffersen-Deb, Benson Kiragu, John N. Hector, Gertrude Anusu, Ponnusamy Saravanan

“…While significant differences were not seen in this cohort, additional investigation is needed to better describe the association of dysglycemia with HIV, especially in Kenyan populations with a higher prevalence of GDM.…”
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Meta-synthesizing of Practices of Corporate Social Responsibility: External Stake-holders Approach by Maryam Khalatbari Moazam, Hamidreza Yazdani, Naser Asgari

“…The classifications of actions related to customers are delineated based on the nature of customer interactions, the quality of customer service provided, the intrinsic qualities of the products, and the delivery methods of these products. Additionally, the expectations of stakeholders compel banks not only to act ethically towards their suppliers and competitors but also to avoid any unethical practices. …”
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The Glucose/Potassium Ratio Exhibits a Predictive Role That is Both Earlier and More Efficacious Compared to The İnflammatory Response in The Context of Isolated Thoracic Trauma by Demet Acar, Emine Kadıoğlu, Nazlı Kenan, Emine Doğan, Asiye Müminat Çap, Yavuz Yılmaz

“… Background/Aim: This study was designed to elucidate the relationship between the AIS 90 thoracic score, which is commonly used to assess the severity of trauma in trauma patients, and the relatively limited studies and data available on the Glucose Potassium Ratio (GPR). Additionally, the study aims to highlight the superiority, if any, of GPR in terms of trauma severity and prognosis, along with the Neutrophil Lymphocyte Ratio (NLR), which plays an important role in trauma severity and prognosis. …”
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AI Chatbots and Cognitive Control: Enhancing Executive Functions Through Chatbot Interactions: A Systematic Review by Pantelis Pergantis, Victoria Bamicha, Charalampos Skianis, Athanasios Drigas

“…It included studies using AI-based chatbots or conversationalists to support executive functions, such as anxiety, stress, depression, memory, attention, cognitive load, and behavioral changes. In addition, this study included general populations with specific neurological conditions, all peer-reviewed, written in English, and with full-text access. …”
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Early Mobilization in Post-Orthopedic Surgery Patients: A Scoping Review by Rhamelani P, Mahdhiya NZ, Yoviana I, Jessica J, Komariah M

“…Maximum care through early mobilization intervention can accelerate the return of body function and minimize medical complications. …”
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Clinical Utility of the Trajectory of Serum Bilirubin and International Normalized Ratio Values in Hepatitis B Virus-Related Acute-on-Chronic Liver Failure by Song YQ, Fu XY, Yan SY, Qi RB, Zhou YJ, Liang JW, Zhang JQ, Ye LP, Mao XL, Li SW

“…Artificial liver support did not improve short-term prognosis for the stable group; instead, it was a risk factor (OR 2.16, 95% CI [0.23– 3.79], P=0.007). …”
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SURGICAL TREATMENT OF PATIENTS WITH RESECTABLE NON SMALL CELL LUNG CANCER by K. I. Kolbanov, A. Kh. Trakhtenberg, O. V. Pikin, V. A. Glushko, A. B. Ryabov

“…The main prognostic factors should be considered the type of the treatment, stage of disease, especially the state of regional hilar lymph nodes. Additional adverse prognostic factor in patients with N0 is adenogenous and macrocellular morphological type of cancer, at N1 - T4 tumors and macrocellular carcinoma, and N2 - Metastasis in some or all areas of the mediastinum and the volume of surgery - bilobectomy.…”
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Association between chronic kidney disease and oxidative balance score: National Health and Nutrition Examination Survey (NHANES) 2005–2018 by Cong Liu, Jiju Yang, Hongdian Li, Yuanyuan Deng, Pengfei He, Jiao Zhang, Mianzhi Zhang, Mianzhi Zhang, Mianzhi Zhang

“…The relationship between OBS and CKD was explored using multiple logistic regression analysis and restricted cubic spline models. Additionally, subgroup analyses, interaction tests, and sensitivity analyses were conducted to validate the stability of the results.ResultsA total of 25,118 NHANES participants were included in this study. …”
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Tousled-like kinase loss confers PARP inhibitor resistance in BRCA1-mutated cancers by impeding non-homologous end joining repair by Min-ah Kim, Banseok Kim, Jihyeon Jeon, Jonghyun Lee, Hyeji Jang, Minjae Baek, Sang-Uk Seo, Dongkwan Shin, Anindya Dutta, Kyung Yong Lee

“…Cell viability assays were conducted to evaluate resistance to PARP inhibitors. Additionally, bioinformatic analyses of public databases were performed to investigate the association between TLK expression and BRCA1 status. …”
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Analisis Pengaruh Kualitas Layanan BCA Mobile terhadap Tingkat Kepuasan dan Liyalitas Nasabh Berdasarkan Model E-S-Qual dan E-Recs-Qual by Roshidah Nur Halimah, Yusi Tyroni Mursityo, Alfi Nur Rusydi

“… Turunnya indeks brand BCA Mobile secara signifikan pada tahun 2019 serta banyaknya kritik terkait layanan di App Store dan Play Store menjadi alasan utama penelitian ini dilakukan, dengan tujuan mengetahui seberapa besar pengaruh mutu layanan BCA Mobile pada kepuasan serta loyalitas nasabah BCA Kota Surabaya. …”
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Effects of Yanghe Decoction on IL-1 and TNF-α of Papain in Rabbit Knee Osteoarthritis by Zhenqiang HONG, Hongjian GAO, Junjun HE, Zeling HUANG

“…The control group and the model group were given 0.9%saline, the Yanghe decoction group was given 6 g/ (kg·d) Yanghe decoction, the Jingu Tongxiao pill group was given 6 g/ (kg·d) Jingu Tongxiao pills. …”
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Learning how to swim in 5- to 12-year-old children: a scoping review of evidence-based motor learning methods by Carola Minkels, Carola Minkels, John van der Kamp, Ralph de Vries, Peter J. Beek, Peter J. Beek

“…Specifically, 87% of studies did not incorporate retention or transfer tests, 35% lacked control or comparison groups, and 48% did not provide detailed descriptions of the investigated intervention(s). …”
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Continuous underground observation of the geomagnetic field in Xuzhou City, North China, and its time-varying characteristics by Mei Han, Mei Han, Lianghui Guo, Lianghui Guo, Lianghui Guo, Yun Wang, Yun Wang, Xiang Wang, Xiang Wang

“…Furthermore, we analyzed the features of the wavelet spectrum of these observed data, variation curves of the geomagnetic field, and coupling of the geomagnetic-field variations between underground and ground. In addition, we investigated the characteristics of different frequency bands and horizontal gradient of the underground geomagnetic variation. …”
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