Protective effects of berbamine against arginase-1 deficiency-induced injury in human brain microvascular endothelial cells by Xiaolan Wei, Weiwei Li, Zixuan Chen, Jintu Chen, Yun Chen, Jiangping Cai, Huasong Lin

“…We examined the effects of ARG1 expression levels on HCMEC/D3 cell viability, migration, apoptosis, adhesion, and angiogenesis through cellular experiments. Additionally, we explored how ARG1 expression levels influenced arginine (Arg), nitric oxide (NO), and ROS levels in HCMEC/D3 cells. …”
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Development and effectiveness evaluation of an interactive e-learning environment to enhance digital health literacy in cancer patients: study protocol for a randomized controlled... by Lukas Lange-Drenth, Hellena Willemer, Mirjam Banse, Anke Ernst, Anne Daubmann, Anja Holz, Christiane Bleich, Susanne Weg-Remers, Holger Schulz

“…However, the quality of online information varies widely and is often inaccurate or does not provide all the details patients need to make informed decisions. Additionally, patients’ often limited ability to find and evaluate cancer-related online information can lead to misinformation.ObjectiveAn interactive e-learning environment to promote digital health literacy will be developed and evaluated for effectiveness.Primary hypothesisCancer patients who use the e-learning environment (IG1.1–IG1.3) or the content of the environment as a non-interactive PDF file (IG2) will show greater improvement in their digital health literacy from baseline to 8 weeks after baseline compared to patients who receive no such intervention, but are referred to a standard information brochure.MethodsThe hypothesis will be tested in a stratified randomized controlled superiority trial with five parallel groups and the primary endpoint of digital health literacy. …”
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Performance of perisel as shelter and periphyton substrate in the floating cage of Pacific white shrimp culture by Rifka Liling Palinggi, Tatag Budiardi, Daniel Djokosetiyanto

“…It was concluded that the addition of perishel inside the floating cage may contribute as natural feed source for the shrimp and thus increase the production performance of shrimp. …”
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Prospects of two-port vitrectomy in the treatment of patients with epiretinal fibrosis by D.V. Borisova, I.A. Frolychev, N.A. Pozdeeva

“…Russian Journal of Clinical Ophthalmology. 2022;22(4):224–227 (in Russ.). DOI: 10.32364/2311-7729-2022-22-4-224-227. </p> <br>…”
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Verbal paired associates learning lateralizes left hippocampal sclerosis in temporal lobe epilepsy by Andy Sitoh, David Weintrob, Jacqueline F. I. Anderson, Angela R. Jackman, Marie F. O'Shea, Graeme D. Jackson, Piero Perucca, Chris Tailby

“…Significance Although the RAVLT delayed recall was the strongest predictor of left‐sided HS, PAL Hard Pairs also demonstrated excellent discriminatory capacity, offering an additional cognitive marker of left hippocampal integrity to complement word list learning in clinical assessments. …”
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Genetic diversity and transmission pattern of multidrug-resistant tuberculosis based on whole-genome sequencing in Wuhan, China by Liqing Wei, Jun Chen, Zhen Deng, Zefang Zhang, Zhengbin Zhang, Qionghong Duan

“…Whole genome sequencing (WGS) was used to identify resistance-conferring mutations, examine their associations with specific Mycobacterium tuberculosis lineages or sublineages, and assess clustering profiles.ResultsAmong the 149 analyzed strains, the most prevalent mutations associated with resistance to 11 anti-tuberculosis drugs were identified as follows: rpoB Ser450Leu (59.73%, rifampicin), katG Ser315Thr (62.42%, isoniazid), embB Met306Val (42.86%, ethambutol), rpsL Lys43Arg (68.13%, streptomycin), pncA Trp68Arg (10.53%, pyrazinamide), gyrA Asp94Gly (22.50%, fluoroquinolones), and rrs 1401A &gt; G (50.00–100.00%, second-line injectable aminoglycosides). Additional mutations were detected in fabG1 c-15C &gt; T (42.86%, ethionamide) and thyX c-16C &gt; T (21.43%, p-aminosalicylic acid). …”
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The Association of Inflammatory Indexes Derived from Peripheral Blood Cell Count and Clinical Signs with Response to Treatment with Dupilumab in Pediatric Patients with Moderate-to... by Zhang L, Pi J, Wang J, Chen J, Zhang Y, Li J, Wang L, Li Y, Chen A, Luo X, Wang H

“…Logistic regression and ROC curve was employed to explore factors associated with treatment efficacy.Results: Baseline ELR and ENR were positively correlated with the baseline Eczema Area and Severity Index (EASI) and the Scoring Atopic Dermatitis (SCORAD). Additionally, baseline ENR levels showed a positive correlation with the baseline Peak Pruritus Numeric Rating Scale (PP-NRS). …”
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Association of MTHFD1 G1958A (rs2236225) gene polymorphism with the risk of congenital heart disease: a systematic review and meta-analysis by Kang Yi, Shao-E He, Tao Guo, Zi-Qiang Wang, Xin Zhang, Jian-Guo Xu, Hao-Yue Zhang, Wei-Guo Liu, Tao You

“…Abstract Background We did this study to better clarify the correlations of methylenetetrahydrofolate dehydrogenase 1 (MTHFD1)-G1958A (rs2236225) gene polymorphism with the risk of congenital heart diseases (CHD) and its subgroups. …”
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Effect of technology application in enhancing the weaknesses of market access, financial resources, and supplier resources on the aluminum industry by M.S. Mohamad Salleh, H. Vasudevan

“…It can assist in identifying areas for additional investment and growth and serve as a guide for planning, carrying out, and assessing economic development efforts. …”
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Defining geosciences research data through metadata reuse: by Alexandre Ribas Semeler, Luana Farias Sales, Adilson Luiz Pinto, Roberta Pereira da Silva de Paula, Valquer Cleyton Paes Gandra, Heloisa Costa

“…The data come from a range of disciplines, including geochemistry, atmospheric science, paleontology, oceanography, geophysics, and hydrology, using technologies such as satellites, electronics microscopes, climate sensors, ships, computer modeling, and others. In addition, the data are augmented by other sources related to the study of the Earth and its processes. …”
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A simple model of the rheological curve of HPAM solutions at different temperatures by Eduar Pérez, Dario Alviso, Mauricio Carmona, Eduardo Manrique, Guillermo Artana

“…The regression model developed was fitted with a training dataset and has exhibited satisfactory results, as tested with additional experimental datasets from different authors. …”
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Are Saudi Radiological Sciences Students Prepared for Emergencies? Exploring Knowledge, and Attitudes Towards Basic Life Support and Cardiopulmonary Resuscitation by Alshamrani KM, Alkhayyat AA, Arif RN, Alahmadi AAS, Aldahery ST, Alsharif WM, Qurashi AA

“…Notably, 80.8% of students without BLS training lacked knowledge of cardiac massage, compared to only 30.4% of those with training. Additionally, 30.6% of students were familiar with defibrillators, and 44.1% knew AED locations (P = 0.0007). …”
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Predictive value of peripheral blood SNORD55 for prognosis of atrial fibrillation patients by WANG Yu, WANG Yu, WU Na, YANG Lanqing

“…In predicting the outcomes of all-cause mortality and stroke， the addition of relative expression SNORD55 level with the CHA2DS2-VASc score obtained higher AUC value ［0.80 （95%CI： 0.67~0.93） vs 0.67 （95%CI： 0.53~0.81）， P<0.05］. …”
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Efficacy and Safety of Recombinant Human Thrombopoietin (rhTPO) on Coagulation Function and Inflammatory Factors in the Treatment of Patients with Sepsis-Related Thrombocytopenia by Huijuan Wang MD, Dong Chen MD, Ming He MD

“…The Group R required significantly fewer red blood cell transfusions compared to the Group C and did not require Plt suspension ( P  < 0.05). No significant differences were found between the groups in terms of mechanical ventilation time, intensive care unit (ICU) length of stay, and total hospital stay ( P  > 0.05). …”
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Evaluation of the effects of thyroid functions on frailty in geriatric patients using the Edmonton, SOF and FRAIL Scales by Galip Can Uyar, Mustafa Kemal Kılıç

“…Abnormal TSH levels were strongly associated with frailty on the SOF scale, suggesting the need to consider thyroid dysfunction as a modifiable risk factor. Additionally, factors such as age, sex, education, thyroid medication use, and comorbidities influenced frailty status. …”
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Investigation on the effectiveness of a new hoof care product to sustainably reduce and prevent digital dermatitis in dairy cow herds by K. Grimm, A. Fiedler, C. Kröger

“…Results B: Two-step regression analysis for the outcome category at evaluation day (with exclusion of the first baseline evaluation) showed that during the trial, compared with the treatment group, odds of having a lesion rather than none was 4 times higher in the control group and the odds of having an active lesion compared with an inactive one were almost 6 times higher in the control group. …”
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Defining ecological thresholds to detect potential ecological risks of offshore wind power using macrobenthic biodiversity and indicator species in Cangnan, China by Wanhong Han, Chen Song, Yurong Zhang, Weiwei Zhou, Yushu Yang, Danyi Ke, Aoxiang Huang, Xiaobo Wang, Qingxi Han

“…Community responses were analyzed via the Shannon–Wiener diversity index, taxonomic β diversity, and conditional probability analysis (CPA) to evaluate the probability of biodiversity damage on the basis of chlorophyll-a (Chl-a) and suspended solids concentrations. Additionally, the pruned exact linear time (PELT) algorithm was applied to detect key CPA change points, and threshold indicator taxa analysis (TITAN) was used to confirm reliable ecological thresholds. …”
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An FPGA-Based SiNW-FET Biosensing System for Real-Time Viral Detection: Hardware Amplification and 1D CNN for Adaptive Noise Reduction by Ahmed Hadded, Mossaad Ben Ayed, Shaya A. Alshaya

“…A high-gain folded-cascade amplifier enhances the Signal-to-Noise Ratio (SNR) to approximately 70 dB, verified through COMSOL and MATLAB simulations. Additionally, a 1D CNN model is employed for adaptive noise reduction, filtering out non-linear noise patterns and achieving an approximate 75% noise reduction across a broad frequency range. …”
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Application of Biochar-Immobilized <i>Bacillus megaterium</i> for Enhancing Phosphorus Uptake and Growth in Rice by Keru Yu, Zhenyu Wang, Wenyan Yang, Shuai Li, Dongtao Wu, Hongtao Zheng, Zhengqian Ye, Shaona Yang, Dan Liu

“…Furthermore, the bioavailable P reservoir (H₂O–Pi and NaHCO₃–Pi) in soil was greatly increased through the fertilizer input and microbial turnover, with the highest H₂O–Pi (3.66 mg kg⁻¹) in OF treatment and the highest NaHCO₃–Pi (52.65 mg kg⁻¹) in MOF treatment. Additionally, carbon utilization analysis was applied using the commercial Biolog system, revealing that the MOF treatment significantly increased the utilization of carbohydrates, polymers, and amino acid carbon sources. …”
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Adherence and efficacy outcomes in young Australians with suicidal ideation using a self-management app and digital engagement strategy compared with a sham app: a three-arm random... by Michelle Torok, Lauren McGillivray, Daniel Z.Q. Gan, Jin Han, Sarah Hetrick, Quincy J.J. Wong

“…Interpretation: A third wave CBT app helped to reduce ideation severity, however providing additional online resources to promote therapeutic engagement did not enhance these effects. …”
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