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65961
BiomiX, a user-friendly bioinformatic tool for democratized analysis and integration of multiomics data
Published 2025-01-01“…The metabolomics annotation for Liquid Chromatography-Mass Spectrometry untargeted metabolomics is additionally supported using the mass-to-charge ratio in the CEU Mass Mediator database and fragmentation spectra in the TidyMass package. …”
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65962
The potential utility of synovial C-reactive protein, interleukin-6, and presepsin in diagnostics of periprosthetic joint infection
Published 2024-12-01“…In cases where synovial leukocyte counts are at borderline levels, the additional assessment of synovial fluid cellular composition and simple, cost-effective markers such as synovial CRP and IL-6 may be recommended to confirm PJI.…”
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65963
‘I no longer worry about money for transport to the health centre’ - economic empowerment of caregivers of children living with HIV through Village Savings and Loan Associations: e...
Published 2025-02-01“…Data were collected through 31 focus group discussions (FGDs) with VSLA members, children and adolescents living with HIV, networks of people living with HIV and Village Health Team members (VHTs). In addition, we conducted 11 interviews with children and their caregivers at TAFU supported health facilities as well as 43 interviews with health workers and district officials involved in HIV programming. …”
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65964
Investigating the effect of using a home safety training application by caregivers on accident risk management in the elderly
Published 2025-01-01“…Repeated measures ANOVA revealed a significant time effect (F(1, 60) = 408, p < 0.001, Partial η2 = 0.872) and a significant group effect (F(1, 60) = 5, p = 0.025, Partial η2 = 0.081). Additionally, the interaction between time and group was significant (F(1, 60) = 6, p = 0.015, Partial η2 = 0.095), indicating a greater improvement in accident risk management scores in the intervention group compared to the control group. …”
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65965
Decarbonizing Saudi Arabia energy and industrial sectors: Assessment of carbon capture cost
Published 2025-03-01“…In contrast, the Western region requires additional focus on storage alternatives such as mineralization. …”
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65966
The Upregulation of IL-1β Induced by Cisplatin Triggers PI3K/AKT/MMP9 Pathway in Pericytes Mediating the Leakage of the Blood Labyrinth Barrier
Published 2025-01-01“…In vitro BLB models, the effect of IL-1β on MMP9 expression, PI3K-AKT pathway activation, and endothelial barrier permeability were examined via Western blot, TEER value test, and FITC extraction analysis. In addition, inhibitors of IL-1β, MMP9, and PI3K-AKT were used to analyze the specific mechanisms.Results: After CDDP treatment, IL-1β upregulation in the stria vascularis disrupted tight junctions, increased BLB permeability, and led to hearing loss. …”
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65967
Prevalence and molecular characteristics of colistin-resistant isolates among carbapenem-resistant Klebsiella pneumoniae in Central South China: a multicenter study
Published 2025-01-01“…Diverse mutations of colistin resistance-related genes were observed, with mgrB inactivation by insertions and the T157P deleterious mutation in pmrB being detected in 57.7% and 42.3% of the colistin-resistant isolates, respectively. In addition, a novel deleterious mutation, R248P, in the crrB gene was found in two ST11 isolates. 88.5% of the 26 isolates presented an increase in pmrK transcription, and 69.2% of them had an overexpression of the pmrC gene. …”
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65968
Effect of KRAS mutation status on clinicopathological characteristics and overall survival in patients with rectal cancer
Published 2025-01-01“…In comparison to the wKRAS group, the overall survival duration was notably reduced in the KRASG12D group (p = 0.0482), whereas no significant difference was observed in the KRASG13D group (p = 0.1848). Additionally, a COX survival analysis was conducted, revealing that KRASG12D, along with higher TNM stage, LVI, tumor deposits, and PNI, were all associated with a decrease in survival time for patients with rectal cancer; however, these factors did not reach statistical significance (p > 0.05). …”
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65969
Buffalo whey proteins performance at the oil/water interface: rheology characterization of the interfacial films
Published 2023-11-01“…Then, the equilibrium interfacial pressure (πeq) was registered through the Wilhelmy plate method. Additionally, adsorption dynamics at the O/W interface at protein concentrations of 0.5 and 1% were obtained over three h with a drop tensiometer. …”
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65970
Study of a Deep Learning Reconstruction Algorithm for Displaying Small- and Medium-sized Blood Vessels in Upper Abdominal Energy Spectrum CT
Published 2025-01-01“…The CT and standard deviation (SD) values of common hepatic, left gastric, splenic, and superior mesenteric arteries were measured, and the CT and SD values of the vertical spinal muscle at the same level were measured. In addition, the signal-to-noise (SNR) and contrast-to-noise (CNR) ratios of each branch vessel were calculated. …”
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65971
Dengue dynamics, predictions, and future increase under changing monsoon climate in India
Published 2025-01-01“…We find that moderate rains spread over the summer monsoon season lead to an increase in dengue mortality, whereas heavy rains reduce it through the flushing effect, indicating the links between dengue and monsoon intraseasonal variability. Additionally, warm temperatures above 27°C and humidity levels between 60% and 78% elevate the risk of dengue. …”
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65972
Influence of elevated temperature exposure on the residual compressive strength and radiation shielding efficiency of ordinary concrete incorporating granodiorite and ceramic powde...
Published 2025-01-01“…The impact of these waste materials on the compressive strength and radiation shielding effectiveness of traditional concrete was evaluated under both ambient and elevated temperature conditions. Additionally, several microstructural tests like X-ray diffraction (XRD), Thermogravimetric analysis (TGA), and Energy dispersive X-ray (EDX) were conducted to assess the influence of using the optimal replacement ratios of the investigated waste powders on the studied properties of concrete. …”
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65973
Effects of Dietary Pectin and Lactobacillus salivarius ATCC 11741 on Growth Performance, Immunocompetence, Gut Microbiota, Antioxidant Capacity, and Disease Resistance in Narrow-Cl...
Published 2022-01-01“…The glutathione peroxidase (GPx) and superoxide dismutase (SOD) activity remarkably enhanced in LS1PE1 and LS2PE2, while malondialdehyde (MDA) content reduced in these two treatments. In addition, specimens belonging to LS1, LS2, PE2, LS1PE1, and LS2PE2 groups presented higher resistance against A. hydrophila compared to the control group. …”
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65974
Can Large Language Models Aid Caregivers of Pediatric Cancer Patients in Information Seeking? A Cross‐Sectional Investigation
Published 2025-01-01“…Five pediatric oncology experts assessed the generated LLM responses using measures including accuracy, clarity, inclusivity, completeness, clinical utility, and overall rating. Additionally, the content quality was evaluated including readability, AI disclosure, source credibility, resource matching, and content originality. …”
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65975
Effects of physical activity on depressive and anxiety symptoms of women in the menopausal transition and menopause: a comprehensive systematic review and meta-analysis of randomiz...
Published 2025-01-01“…Abstract Background Depression and anxiety may significantly affect women in the menopausal transition and menopause. In addition to traditional treatment strategies such as hormone therapy, antidepressants, and psychotherapy, physical activity (PA) have been increasingly studied, but there is no consensus about their role in menopausal women with depression and anxiety. …”
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65976
Exploring the correlations between six serological inflammatory markers and different stages of type 2 diabetic retinopathy
Published 2025-01-01“…Abstract To determine the correlations between six serological inflammatory markers, namely the systemic immune-inflammation index (SII), systemic inflammatory response index (SIRI), aggregate index of systemic inflammation (AISI), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR), and various stages of type 2 diabetic retinopathy (T2DR). Additionally, the diagnostic value of these markers in T2DR was evaluated. …”
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65977
Gastric Peroral Endoscopic Myotomy (G-POEM) as a Treatment for Refractory Gastroparesis: Long-Term Outcomes
Published 2018-01-01“…This study included 11 males and 5 females; in addition, 13 patients had postsurgical gastroparesis, and 3 patients had diabetes. …”
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65978
The Association between ER, PR, HER2, and ER−/PR+ Expression and Lung Cancer Subsequent in Breast Cancer Patients: A Retrospective Cohort Study Based on SEER Database
Published 2023-01-01“…Furthermore, it appears that the prognosis of BC-LuC may be influenced by the presence of ER+ and PR+. Therefore, additional research is warranted to fully investigate and validate this association.…”
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65979
Trends and Gaps in Digital Precision Hypertension Management: Scoping Review
Published 2025-02-01“…In total, 45% (21/46) of the studies either did not report race or ethnicity data (14/46, 30%) or partially reported this information (7/46, 15%). …”
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65980
Exploration of pulse wave analysis under reactive hyperemia and close to an arteriovenous fistula: a comparative analysis
Published 2025-02-01“…The area under the curve and the mean slope between the systolic peak and the end of systole of pulse waves and duplex flow velocities were analysed as parameter differences under high flow and physiological conditions (∆A2 and ∆m2, ∆Vmax and ∆Vdiast). In addition, the augmentation index was evaluated (only) under physiological conditions. …”
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