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65781
Increasing Access to Mental Health Supports for 18- to 25-Year-Old Indigenous Youth With the JoyPop Mobile Mental Health App: Study Protocol for a Randomized Controlled Trial
Published 2025-01-01“… BackgroundTransitional-aged youth have a high burden of mental health difficulties in Canada, with Indigenous youth, in particular, experiencing additional circumstances that challenge their well-being. …”
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65782
The Climate-forming role of the production process of the forests of Ukraine
Published 2024-09-01“…The indicators of the material-and-energy balance that determine the general enrichment of the air with oxygen (atomic), which is a useful environment-forming sanitary and hygienic factor, grow in proportion to the productivity of the stands. In addition, large masses of water vapor moisten the air and significantly cool it. …”
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65783
The dual anti-inflammatory and anticoagulant effects of Jianpi Huashi Tongluo prescription on Rheumatoid Arthritis through inhibiting the activation of the PI3K/AKT signaling pathw...
Published 2025-02-01“…Furthermore, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) results suggested that the pharmacodynamic mechanism of XFC may be closely related to the regulation of the PI3K/AKT signaling pathway. Additionally, network pharmacology and molecular docking results show that the main active components of XFC, namely, calycosin-7-O-beta-D-glucoside, calycosin, and formononetin, exhibit excellent docking with the core targets HIF1A, PTGS2, and MMP9. …”
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65784
MANAGING MAXILLARY BONE LOSS USING GROWTH FACTORS IN PRE-IMPLANT THERAPY
Published 2024-06-01“…A retrospective study by Dragonas et al. (2020) reported a remarkable implant survival rate of 95.8% one year post-augmentation using PRGF combined with various bone grafts. Additionally, a case report by Raţiu et al. (2018) documented significant osseous regeneration over eight months following augmentation performed solely with PRGF and fibrin clot, with histological examination confirming new bone formation. …”
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65785
Health Care Professionals and Data Scientists’ Perspectives on a Machine Learning System to Anticipate and Manage the Risk of Decompensation From Patients With Heart Failure: Quali...
Published 2025-01-01“…Adequate variable selection, risk stratification, and response models were identified as essential components for the effective implementation of ML models in health care. In addition, the study identified technical, regulatory and ethical, and adoption and acceptance challenges that need to be overcome for the successful integration of ML models into clinical workflows. …”
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65786
Corneal nerve abnormalities in early-stage diabetic retinopathy evaluated by corneal confocal microscopy
Published 2025-01-01“…We collected the clinical data (gender, age, body mass index), laboratory indicators (fasting blood glucose, glycosylated hemoglobin), and confocal laser scanning microscopy images for further analysis. …”
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65787
Telomerase inhibiting phytochemicals derived from Blumea eriantha for cancer treatment: A comprehensive computational analysis
Published 2025-02-01“…The phytochemical also exhibited a robust binding affinity mediated by consistent magnesium metal ion interactions involving key residues such as Asp251, Asp252, Ile252, and Asp343, along with additional hydrogen bonding and water-mediated contacts that enhance its stability and selectivity. …”
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65788
MLinvitroTox reloaded for high-throughput hazard-based prioritization of high-resolution mass spectrometry data
Published 2025-01-01“…While the original proof of concept study was accompanied by the release of a MLinvitroTox v1 KNIME workflow, in this study, we release a Python MLinvitroTox v2 package, which, in addition to automation, expands functionality to include predicting toxicity from structures, cleaning up and generating chemical fingerprints, customizing models, and retraining on custom data. …”
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65789
Anti-inflammatory treatment using alpha melanocyte stimulating hormone (α-MSH) does not alter osteoblasts differentiation and fracture healing
Published 2025-02-01“…Bone tissue is significantly affected in inflammatory joint diseases. Additionally, inflammatory signaling is essential -in bone regeneration during fracture healing. …”
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65790
Three-dimensional evaluation of tongue position and volume in adult patients with different skeletal malocclusions
Published 2025-01-01“…Tongue volume was positively correlated with U1-SN and negatively correlated with overbite and overjet (<i>P </i>< 0.05). Additionally, tongue volume showed a significant positive correlation with Go-Gn and Pg-Np (<i>P </i>< 0.01), as well as with maxillary and mandibular dental arch width and basal bone arch width (<i>P </i>< 0.01). …”
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65791
Digital Platform for Pediatric Mental Health Support During Armed Conflicts: Development and Usability Study
Published 2024-12-01“…The goal was to create a comprehensive resource that addresses a wide range of emotional and behavioral challenges in children and adolescents, with a particular focus on those affected by armed conflict and significant trauma exposure. In addition, the study aimed to evaluate the platform’s usability and relevance through feedback from primary users, thereby assessing its potential for implementation in pediatric practice. …”
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65792
BananaImageBD: A comprehensive banana image dataset for classification of banana varieties and detection of ripeness stages in BangladeshMendeley Data
Published 2025-02-01“…Such ML and DL models can be leveraged to develop automated systems to determine the optimal harvest time, establish standards for quality control of bananas, develop products and marketing strategies through analysis of consumer preferences for various banana varieties and ripeness levels, and streamline the banana supply chain through improvements in harvesting, sorting, packaging, and inventory management. Additionally, researchers aiming to contribute to developing Computer Vision technologies in food and agricultural sciences will find this dataset valuable in advancing precision farming and food processing mechanisms. …”
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65793
Association Between Diurnal Temperature Range and Risk of Cardiomyopathy-Induced Hospitalisation in Henan, China: A Time-Series Study
Published 2025-01-01“…Zhaolin Zhang,1,* Yongbin Wang,2,* Yifeng Zhou,1 Jiachao Pei,1 Guoan Zhao,1,3 Pingshuan Dong,4 Kan Yang,5 Hui Liu,6 Na Xie,7 Xuefang Li,3 Xiayan Zang,3 Fei Lin,1,3 Zhigang Chen1 1Department of Cardiology,The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, People’s Republic of China; 2Department of Epidemiology and Health Statistics, Xinxiang Medical University, Xinxiang, 453003, People’s Republic of China; 3Henan Engineering Technology Research Center of Environmental Meteorological Medicine, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, People’s Republic of China; 4Department of Cardiology,The First Affiliated Hospital of Henan University of Science and Technology, Luoyan, 471000, People’s Republic of China; 5Department of Cardiology,Nanyang Central Hospital, Nanyang, 473005, People’s Republic of China; 6Department of Cardiology,Anyang District Hospital, Anyang, 455000, People’s Republic of China; 7Department of Cardiology,The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, 453003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fei Lin; Zhigang Chen, Department of Cardiology,The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui, Henan, People’s Republic of China, Tel +86 18567557937, Email 1fy2000129@xxmu.edu.cn; 1fy2015157@xxmu.edu.cnPurpose: The effect of the diurnal temperature range (DTR) on human health in diverse geographic areas and the potential confounding factors are not fully understood. Additionally, while a robust association has been reported between temperature and cardiomyopathy (CM), evidence of the impact of DTR is relatively limited. …”
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65794
Research on the impact of land use and land cover changes on local meteorological conditions and surface ozone in the north China plain from 2001 to 2020
Published 2025-01-01“…Below 500 m, vertical transport increased O3 concentrations, while horizontal transport decreased O3 concentrations. Additionally, the meteorological and chemical processes induced by LULCC showed enhanced effects above the surface, whereas the dry deposition process had a smaller impact on O3 concentrations above the surface. …”
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65795
The application of biochar and organic fertilizer substitution regulates the diversities of habitat specialist bacterial communities within soil aggregates in proso millet farmland
Published 2025-01-01“…The impacts of biochar and fertilizer additions, as well as soil aggregates, on the community structure and composition of specialists were greater than those of generalists. …”
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65796
Modeling Stock High-Low Price Range: Fractional Cointegrating VAR Approach (FCVAR)
Published 2024-03-01“…ObjectiveThis paper seeks to employ fractional cointegration methodology to model high and low stock prices, as well as the range series, indicating the difference between high and low stock prices. Additionally, it tries to examine the regime-switching characteristic in the cointegrating relationship between price series. …”
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65797
The impact of side and top arm techniques during the backstroke breakout phase on 15-meter swimming performance
Published 2025-01-01“…Results Both male and female swimmers exhibited a significantly faster top arm velocities of (1.72 ± 0.20 and 1.47 ± 0.16 m/s, respectively) compared to the side arm velocities (1.51 ± 0.23 and 1.29 ± 0.19 m/s, respectively) during the breakout phase. Additionally, significant differences were found between the two genders (F = 11.189, p = 0.002, η2 = 0.286) and breakout techniques (F = 8.014, p = 0.008, η2 = 0.223), with no interaction effect (F = 0.037, p = 0.849, η2 = 0.001). …”
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65798
Pharmacokinetics of 7,8-dihydroxyflavone in neonatal mice with hypoxia-ischemia related brain injury
Published 2025-01-01“…The distribution of 7,8-DHF to the brain was rapid; however, the extent of brain distribution was low with the right and left brain-to-plasma partition coefficients being 8.6% and 9.9%, respectively. Additionally, both O-methylated metabolites of 7,8-DHF were detected in the plasma and brain.ConclusionThe plasma and brain PK of 7,8-DHF in neonatal mice were similar between males and females. …”
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65799
Syntheses and structures of two coordination polymers formed by Ni(cyclam)2+ cations and sulfate anions
Published 2025-02-01“…In II it includes additionally a molecule of the undissociated acid (2,2′,4,4′,6,6′-hexamethyl[1,1′-biphenyl]-3,3′,5,5′-tetrayl)tetra(benzoic acid) located on a crystallographic twofold axis and nine highly disordered water molecules of crystallization. …”
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65800
Preparation, Modification, Characterization and Antioxidant Activities of Apigenin Liposomes
Published 2025-01-01“…The particle size of AP-L was 157.34±1.87 nm, the polydispersity index (PDI) was 0.240±0.025, and the encapsulation efficiency was 66.50%±1.00%. …”
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