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65761
Racial differences in takotsubo cardiomyopathy outcomes in a large nationwide sample
Published 2020-06-01“…After the adjustment for differences in age, gender, comorbidities (using the enhanced Charlson comorbidity index), hospital location/teaching status, and socio‐economic factors, all differences were significantly attenuated or eliminated. Additionally, the adjusted risk was lower in AA compared with Caucasians, for cardiogenic shock [odds ratio (OR) 0.61 (0.47–0.78), P < 0.0001], mechanical ventilation [OR 0.8 (0.70–0.92), P = 0.002] and intraaortic balloon pump insertion [OR 0.63 (0.41–0.99), P = 0.04]. …”
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65762
miR-129-5p Promotes Osteogenic Differentiation of BMSCs and Bone Regeneration via Repressing Dkk3
Published 2021-01-01“…Luciferase and western blot data showed that Dickkopf3 (Dkk3) is a target gene of miR-129-5p and the expression of Dkk3 was inhibited in BMSCs transduced with miR-129-5p mimic but enhanced in BMSCs transduced with miR-129-5p inhibitor. In addition, Dkk3 interacted with β-catenin directly. …”
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65763
The StbHLH47 transcription factor negatively regulates drought tolerance in potato (Solanum tuberosum L.)
Published 2025-01-01“…Therefore, it is speculated that StbHLH47 may regulate drought resistance mainly through these two pathways. Additionally, RT‒qPCR was used for fluorescence quantification of the expression of StNCED1 and StERD11, which are known for their drought resistance, and the results revealed that the expression levels were much lower in OE-StbHLH47 than in WT plants. …”
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65764
Managing cardiovascular events, hyperglycemia, and obesity in type 2 diabetes through microRNA regulation linked to glucagon-like peptide-1 receptor agonists
Published 2025-01-01“…Eventually, GLP-1RAs regulation of exosomal miRNAs, such as miR-192, implicated in the development of fibrosis and inflammation in T2DM micro-cardiovascular outcomes like DKD and DR. Conclusion Additional studies will be needed in the elucidation of the relations between GLP-1RA-induced miRNAs and clinical-laboratory findings concerning the diverse populations, gender, and presence of other comorbid states in treated patients with T2DM.…”
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65765
Eco-benign synthesis of multifunctional silver nanoparticles using leptochloa fusca for enhanced biomedical and catalytic applications
Published 2025-01-01“…The biosynthesized LF-AgNPs were also found to have effective antioxidant (70%) and H _2 O _2 scavenging (77%) properties. Additionally, the agar well diffusion technique demonstrated efficient antibacterial efficacy for LF-AgNPs against both Gram +ve ( Staphylococcus aureus ) and Gram -ve ( Klebsiella pneumoniae ) strains with ZOI values of 19 ± 0.7 mm and 19 ± 0.5 mm, respectively. …”
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65766
Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfu...
Published 2025-02-01“…Compared with the IR group, the above indexes were all alleviated in the IR+Fer-1 or IR+ATF3KD groups. In addition, the protein expressions of ATF3, Nrf2 and HO-1 in the IR group were increased than those in sham group. …”
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65767
Immune regulatory genes impact the hot/cold tumor microenvironment, affecting cancer treatment and patient outcomes
Published 2025-01-01“…Kyoto Encyclopedia of Genes and Genomes and Hallmark pathway enrichment were evaluated through gene set variation analysis. Additionally, hub genes that regulate the tumor microenvironment were identified, and their expression patterns were analyzed using single-cell RNA sequencing. …”
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65768
Social Media Use and Oral Health–Related Misconceptions in Saudi Arabia: Cross-Sectional Study
Published 2025-02-01“…Logistic regression models provided odds ratios and adjusted odds ratios with 95% CI to assess the presence of oral health misconceptions. …”
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65769
Prioritization of Alternative Agricultural Products Based on Market Signals as a Tool for the Development of Innovative Projects
Published 2021-08-01“…The definition of a set of agricultural products with high potential at the primary level and/or in agroindustrial processes that are not deeply explored required determining market signals to identify new medium- and long-term commercial possibilities for Chimborazo farmers. Additionally, it was recognized that the management of the province of Chimborazo was based on its management of the Millennium Development Goals, the Constitution of the Republic, the National Plan for Development in a Supra-Provincial Framework, as well as the Plan Development of Chimborazo, the Territorial Planning Plan and others that promoted planning with a focus on territorial and solidarity sustainable development. …”
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65770
Boosting electrocatalytic generation of FDCA and H2 from 2,5-furanedimethanol solution by carbonized wood supported Fe-CoP nanoleaves
Published 2025-01-01“…The obtained Fe-CoP/CW as an anode in FDM solution afforded a current density of 100 mA cm−2 with a yield of 90% FDCA at a potential no more than 1.50 V vs RHE, which was 90 mV and 350 mV lower than Fe-CoP/carbon cloth (CC) and IrO2. In addition, Fe-CoP/CW showed excellent long-term stability for 108-h FDM oxidation in strong alkaline solution. …”
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65771
Inhibition of p70 Ribosomal S6K1 Protects the Myocardium against Ischemia/Reperfusion-Induced Necrosis through Downregulation of RIP3
Published 2025-01-01“…Results: Inhibition of S6K1 reduces I/R-induced myocardial tissue damage, improves myocardial function, and inhibits myocardial tissue necrosis (p < 0.05). In addition, RIP3 is a direct target of S6K1, and activation of RIP3 blocked the protective effect of the S6K1 inhibitor PF-4708671 against myocardial I/R injury (p < 0.05). …”
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65772
Exploring the relationship between mental health issues and academic performance of undergraduate students in a Ghanaian tertiary institution: a cross-sectional study
Published 2025-01-01“…This study investigated the relationship between mental health incidence and academic performance among university students in a public university in Ghana. Additionally, we study students’ level of mental health awareness. …”
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65773
Life cycle assessment of agricultural waste recycling for sustainable environmental impact
Published 2024-01-01“…When integrating agricultural waste, including composting, anaerobic digestion, and pyrolysis, biochar is highlighted as a waste recycling method that is promising for sustainable waste management. In addition to efficiently managing agricultural waste, these technologies help generate electricity and sequester carbon, thereby advancing the objectives of climate change mitigation and circular economy. …”
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65774
Factors influencing gender and youth integration in agricultural research and innovation in Africa
Published 2024-02-01“…There is increased recognition among the research and development community that effective gender and youth integration in R & I would help increase the adoption of products, services, and processes of R & I. In addition, gender and youth integration helps in the promotion and dissemination of R & I as well as in increasing accessibility of innovation and technology by end users. …”
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65775
Investigating the Asymmetric Impact of the Stock Market Index on the Real Estate Price Index
Published 2024-03-01“…This is because high returns in the stock market augment the overall wealth of homeowners, enhancing their capacity to invest in additional real estate. Therefore, the stock market index can have a positive or negative effect on housing prices. …”
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65776
Prevalence and Determinants of Home Delivery among Women with Easy Access to Health Facilities in Sub-Saharan African Countries: A Multi-level Mixed Effect Analysis
Published 2025-01-01“…To develop appropriate policies and methods that could aid in addressing the issues, it is important to understand the burden of home delivery despite having easy access to health facilities in low-income nations such as sub-Saharan Africa. In addition, identifying and prioritizing determinants could help executives to review their perinatal policies. …”
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65777
Circular economy and inclusion as effective tools to prevent ecological threats in rural areas during military operations
Published 2024-07-01“…The main methods applied included quantitative data analysis through regression modeling, which helped identify the relationship between the level of inclusion and circular economy practices with changes in the level of ecological threaten. Additionally, the use of taxonomy allowed determining the level of ecological threaten, while cluster analysis was used to distribute territories based on the level of ecological threaten ecocide. …”
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65778
Magnitude of consistent condom use and associated factors among people living with HIV/AIDS in Ethiopia: Implication for reducing infections and re-infection. A systematic review a...
Published 2024-01-01“…The factors associated with a consistent use of condom were described using the pooled odds ratio (OR) and calculated based on binary outcomes from the included primary studies. …”
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65779
Effects of exercise intensity and diet on cardiac tissue structure and FGF21/β-Klotho signaling in type 2 diabetic mice: a comparative study of HFD and HFD + STZ induced type 2 dia...
Published 2025-01-01“…Post hoc and subgroup analysis showed a superior effect of MICT over HIIT in decreasing fasting blood glucose and serum level of FGF21 (p < 0.001). Additionally, the results of the myocardial tissue qualitative analyses differed between the diabetic mouse models and the ET groups. …”
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65780
The landscape of immunogenic cell death-related genes predicts the overall survival and immune infiltration status of non-small-cell lung carcinoma
Published 2025-01-01“…The results of the external validation were then used to identify the appropriate genes for use in predicting the survival outcome of patients with this type of cancer. In addition, a nomogram was created to help visualise the clinical presentation of the patients. …”
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