Effect of multispecies swards on ruminal fermentation, methane emission and potential for climate care cattle farming − an in vitro study by M.U. Hassan, P. Sidoruk, D. Lechniak, M. Szumacher-Strabel, J. Bocianowski, S. Ślusarczyk, P.R. Hargreaves, D. Ruska, A. Dorbe, Dz. Kreismane, K. Klumpp, J. Bloor, R.M. Rees, A. Kuipers, P. Galama, Z. Váradyová, K. Čobanová, A. Cieślak

“…This plant blend also increased propionate concentration (P < 0.05) and reduced acetate and butyrate concentrations and the acetate-propionate ratio (P < 0.01). Additionally, the total protozoal and methanogen counts were mostly reduced by the PLA+RC blend (P < 0.01) among all blends investigated. …”
Get full text

AutoLDP: An accurate and efficient artificial intelligence-based tool for automatic labeling of digital pathology by Yingnan Zhao, Huifen Ye, Jing Yang, Su Yao, Maohua Lv, Zhihong Chen, Yunrui Ye, Qingru Hu, Cheng Lu, Zaiyi Liu, Ke Zhao, Zhihua Chen

“…The results show that we achieved an accuracy of 97.60 ​% in just 87.62 ​s in validation set 1 with 200 cases, which was significantly better than that of the other models. In addition, the accuracy reached 96.98 ​% in validation set 2 with 13,667 cases, confirming the generalization ability of the model. …”
Get full text

Genotype-driven sensitivity of mice to tick-borne encephalitis virus correlates with differential host responses in peripheral macrophages and brain by Michaela Berankova, Jiri Holoubek, Vaclav Hönig, Zuzana Matusova, Martin Palus, Jiri Salat, Imtissal Krayem, Jarmila Vojtiskova, Pavel Svoboda, Veronika Pranclova, Lukas Valihrach, Peter Demant, Marie Lipoldova, Daniel Ruzek

“…Methods TBEV growth and the production of key cytokines and chemokines were measured and compared in macrophages derived from BALB/c, CcS-11, and STS mice. In addition, brains from these TBEV-infected mouse strains underwent in-depth transcriptomic analysis. …”
Get full text

Early Myocardial Strain Reduction and miR-122-5p Elevation Associated with Interstitial Fibrosis in Anthracycline-Induced Cardiotoxicity by María de Regla Caballero-Valderrama, Elisa Bevilacqua, Miriam Echevarría, Francisco Javier Salvador-Bofill, Antonio Ordóñez, José Eduardo López-Haldón, Tarik Smani, Eva M. Calderón-Sánchez

“…Methods: Echocardiography and blood tests were examined in 33 breast cancer patients with low baseline risk for cardiotoxicity during anthracycline treatment, with a follow-up at 12 months. Additionally, 16 Wistar rats received epirubicin (20 mg/kg over 4 weeks) to examine cardiac strain and structural changes. …”
Get full text

Angelica sinensis polysaccharide as potential protectants against recurrent spontaneous abortion: focus on autophagy regulation by Yeli Sun, Guohua Li, Mengwen Kong, Junyuan Li, Shuyun Wang, Yuan Tan

“…Autophagy flux in the decidua was compared between eight RSA patients and eight healthy pregnant women. Additionally, changes in autophagy flux were assessed in an RSA mouse model following ASP treatment, with embryos and placental tissues collected for subsequent metabolomic profiling.ResultsOur results revealed a significant reduction in Beclin 1 protein levels in the decidua of RSA patients compared to the normal pregnancy group. …”
Get full text

Mavi Kod çağrısına bağlı kardiyo-pulmoner resüsitasyon uygulamaları sonuçlarının değerlendirilmesi by Sait Selçuk Atıcı, Faruk Çiçekci

Subjects: “…mavi kod…”
Get full text

Genome-wide linkage mapping of Fusarium crown rot in common wheat (Triticum aestivum L.) by Faji Li, Can Guo, Qi Zhao, Weie Wen, Shengnan Zhai, Xinyou Cao, Cheng Liu, Dungong Cheng, Jun Guo, Yan Zi, Aifeng Liu, Jianmin Song, Jianjun Liu, Jindong Liu, Haosheng Li

“…The favorable alleles of QFCR.caas-3DL and QFCR.caas-5BL were contributed by Zhoumai 16, while the favorable alleles for QFCR.caas-3AL, QFCR.caas-6BS, and QFCR.caas-7DS originated from Gaocheng 8901. Additionally, this study identified seven candidate genes that encode disease resistance proteins, the BTB/POZ domains, peroxidase activity, and leucine-rich repeat receptor-like protein kinase. …”
Get full text

A Network Pharmacology-Based Strategy for Unveiling the Mechanisms of Tripterygium Wilfordii Hook F against Diabetic Kidney Disease by Yuyang Wang, Tongtong Liu, Fang Ma, Xiaoguang Lu, Huimin Mao, Weie Zhou, Liping Yang, Ping Li, Yongli Zhan

“…Diabetic kidney disease (DKD) poses a major public-health burden globally. …”
Get full text

Metabolic response to burn injury: a comprehensive bibliometric study by Yixu Li, Yixu Li, Yifan Liu, Sujie Xie, Sujie Xie, Yushu Zhu, Yushu Zhu, Xinran Ding, Xinran Ding, Wei Zhang, Wei Zhang, Shuyuan Xian, Shuyuan Xian, Guosheng Wu, Guosheng Wu, Hanlin Sun, Hanlin Sun, Jiale Yan, Bingnan Lu, Yuntao Yao, Weijin Qian, Yuwei Lu, Yiting Yang, Dayuan Xu, Dayuan Xu, Runzhi Huang, Runzhi Huang, Shizhao Ji, Shizhao Ji

“…The role of propranolol, insulin, oxandrolone, and nutritional interventions in modulating the hypermetabolic state was discussed. Additionally, our study underscored the challenges of managing sepsis and drug-resistant infections in burn patients as an important future area of research.…”
Get full text

Associations of sociodemographic and smoking characteristics with intention to quit among Chinese adults aged 20–69 years who smoke: Findings from nationwide China Health Literacy... by Zhen-xiao Huang, Ying-hua Li, Ying Xie, Yi Liu, Zheng Su, Xin Xia, Dan Xiao, Chen Wang

“…Objective: To identify factors influencing the intention to quit (ItQ) among Chinese who smoke, focusing on 10th Revision of the International Classification of Diseases (ICD-10) Nicotine dependence. Additionally, to estimate the number of individuals with ItQ, supporting optimal allocation of cessation resources. …”
Get full text

Burden of NASH related liver cancer from 1990 to 2021 at the global, regional, and national levels by Shuang Li, Shuang Li, Shuangjiang Li, Linjing Guan, Mingjuan Li, Jiahui Zhao, Min Wu, Qiuyun Li, Hui Li, Guoqing Ouyang, Guangdong Pan, Guangdong Pan

“…Regionally, ASRs initially declined but then increased as SDI rose. At the national level, ASRs consistently decreased with higher SDI.ConclusionThis study highlights the substantial burden of NRLC at global, regional, and national levels. …”
Get full text

Spatial transcriptomics reveals unique metabolic profile and key oncogenic regulators of cervical squamous cell carcinoma by Limin Zhou, Jiejie Liu, Peipei Yao, Xing Liu, Fei Chen, Yu Chen, Li Zhou, Chao Shen, You Zhou, Xin Du, Junbo Hu

“…Conclusions Utilizing ST, scRNA-seq, and TCGA database, we examined the spatial metabolic profiles of CSCC tissues, including metabolism distribution, metabolic variations, and the relationship between metabolism and tumor differentiation degree. Additionally, potential cancer-promoting factors were proposed, offering a valuable foundation for the development of more effective treatment strategies for CSCC.…”
Get full text

Effects of intranasal oxytocin on neural reward processing in children and adolescents with reactive attachment disorder: A randomized controlled trial by Shinichiro Takiguchi, Shinichiro Takiguchi, Kai Makita, Takashi X. Fujisawa, Takashi X. Fujisawa, Shota Nishitani, Shota Nishitani, Akemi Tomoda, Akemi Tomoda, Akemi Tomoda

“…In the RAD group, OT significantly increased subjective motivation scores, significantly enhanced activation in the right middle frontal gyrus, and reduced activation in the right precentral gyrus during the monetary reward task. Additional analyses revealed increased activation in the bilateral caudate at a more lenient threshold. …”
Get full text

One-pot synthesis and characterization of a BSA-Cu2S/CuS quantum dots drug delivery system based on biuret’s reaction by Porfirio Estrada-Rojas, Juan Francisco Hernández-Paz, Claudia Alejandra Rodríguez-González, Mónica Elvira Mendoza-Duarte, Santos Adriana Martel-Estrada, Laura Elizabeth Valencia-Gómez, Héctor Camacho-Montes, Imelda Olivas-Armendáriz

“…Fourier-transform infrared (FTIR) spectroscopy confirmed the structural integrity of BSA after functionalization, while x-ray diffraction (XRD) analysis verified the formation of CuS and Cu _2 S crystals. Additional tests, including fluorescence and UV–vis spectroscopy, validated the optical properties of the quantum dots. …”
Get full text

Efficacy of Fetal Wharton’s Jelly Mesenchymal Stem Cells-Derived Small Extracellular Vesicles in Metabolic Syndrome by Illayaraja Krishnan, Magdalene Tan Mei Ling, Min Hwei Ng, Jia Xian Law, Mohd Rafizul Mohd Yusof, Thavachelvi Thangarajah, Zalina Mahmood, Nurul Izzati Uda Zahli, Shathiya Rajamanickam, Baskar Subramani, Yogeswaran Lokanathan

“…Non-significant associations were found between fasting CRP, leptin, and adiponectin levels with MetS rats after treatment. In addition, sEVs preparations improved inflammation and hemorrhage in the lung and mineralisation in the renal of the treated group. …”
Get full text

Establishment and evaluation of a UPLC-MS/MS method for simultaneous determination of bongkrekic acid and dehydroacetic acid in rice noodles by Lingguo Zhao, Ronggui Lv, Ronggui Lv, Jiang Song, Xi Chen, Lei Lei, Weixian Zeng, Miaowen She, Miaowen She, Dabing Li, Xiaxia Yu, Zhanguo Liu, Xiao Wang, Yong Liu

“…The limits of detection (LOD) were determined to be 0.1 μg/kg for BA and 0.6 μg/kg for DHA. Additionally, the method exhibited good recovery of 90.1%∼105.4% for BA and 80.4%∼102% for DHA. …”
Get full text

High Data-Rate Hilbert-Curved-Shaped MIMO Antenna With Improved Bandwidth and Circular Polarization for Wireless Capsule Endoscopy by Syed Misbah Un Noor, Syed Ahson Ali Shah, Shahid Khan, Izaz Ali Shah, Jamal Nasir, Salahuddin Khan, Slawomir Koziel

“…Simultaneously, employing the curve&#x2019;s inherent natural symmetry and adopting an orthogonal port arrangement led to a noteworthy improvement in isolation up to 27 dB with an enhanced gain of &#x2212;27.9 dBi. Comprehensive simulation analysis of antenna-integrated WCE systems in homogeneous and hetrogenous environments is conducted in the stomach, small intestine, and large intestine. …”
Get full text

DFT and molecular docking analyses of the effects of solvent polarity and temperature on the structural, electronic, and thermodynamic properties of p-coumaric acid: Insights for a... by Umer Sherefedin, Abebe Belay, Kusse Gudishe, Alemu Kebede, Alemayehu Getahun Kumela, Tadesse Lemma Wakjira, Dereje Gelanu, Tesfaye Feyise, Jebel Haji Mahamud, Abdulkerim Abdela, Kebede Shankute Gizew

“…This work investigated the impact of these factors via computational techniques, including semiempirical methods (MP6), Hartree–Fock (HF) calculations with the 6-311＋＋G (d, p) basis set, and density functional theory (DFT) with various basis sets, such as STO-3G*, SDD, 3-21＋G*, Aug-CC-pVDZ, 6-31＋＋G (d, p), LANL2DZ, 6-31＋＋G’ (d, p), and 6-311＋＋G (d, p). …”
Get full text

Triglyceride-independent associations between circulating levels of apolipoprotein C-III and biomarkers of inflammation by Dídac Llop, Pere Rehues, Silvia Paredes, Montse Guardiola, Josefa Girona, Roser Rosales, Yaiza Esteban, Lluís Masana, Daiana Ibarretxe, Joan-Carles Vallvé, Josep Ribalta

“…Our results suggest that apoCIII is associated with the low-grade inflammatory profile represented by glycoproteins, independent of triglyceride levels. Additionally, we observed a negative association with hsCRP, which, while seemingly paradoxical, has been reported in previous studies.…”
Get full text

Efficacy of TIPS plus extrahepatic collateral embolisation in real-world data: a validation study by Chao Chen, Feng Zhang, Hao Wu, Wei Wu, Hui Xue, Yuzheng Zhuge, Chunqing Zhang, Guangchuan Wang, Zhengjie Li, Qiong Wu, Bo Wei, Jun Tie, Xiubin Sun, Lianhui Zhao, Yifu Xia, Jiao Xu, Peijie Li

“…However, there were no differences in overall or subgroup survival analysis. Additionally, the random forest models showed higher accuracy and AUROC comparing to other models. …”
Get full text