Crisis response strategies of universities during the ongoing war: Beyond experience and responsibilities by Oleksandr Spivakovsky, Serhii Omelchuk, Daria Malchykova

“…Department of State’s Bureau of Educational and Cultural Affairs (ECA), with additional funding provided by Harvard University and administered by the American Councils for International Education. …”
Get full text

Are Electromyography Data a Fingerprint for Patients with Cerebral Palsy (CP)? by Mehrdad Davoudi, Firooz Salami, Robert Reisig, Dimitrios A. Patikas, Nicholas A. Beckmann, Katharina S. Gather, Sebastian I. Wolf

“…Using Repeated Measures ANOVA, we examined the norm-distance (ND) of the kinematics, kinetics, and EMG patterns, in addition to the Kerpape-Rennes EMG-based Gait Index (EDI), EMG Profile Score (EPS), and Walking Dynamic Motor Control Index (DMC) before and after surgery. …”
Get full text

Association of female genital schistosomiasis and human papillomavirus and cervical pre-cancer: a systematic review by Amy Sturt, Tanvier Omar, Isaiah Hansingo, Paul Kamfwa, Amaya Bustinduy, Helen Kelly

“…However, a study in Madagascar did not show increased odds of any HPV among women with visual-FGS compared to women without FGS (OR 1.0 [0.82 – 1.2). …”
Get full text

SUMO modified ETV1 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by facilitating CCL2 transcription in esophageal squamous cell carcinoma ce... by Tianci Han, Xiaoqi Guo, Junwei Xie, Wei Tong, Liang Zhang

“…Mechanism study demonstrated that ETV1 facilitated M2 macrophage infiltration via the transcriptional modulation of CCL2. In addition, the cause of the changes in ETV1 activity and expression was investigated. …”
Get full text

Diagnostic value of interleukins 23 and 17 in the assessment of ulcerative colitis severity by M.V. Stoikevych, O.M. Tatarchuk, T.S. Tarasova

“…The median level of IL-23 was significantly higher in moderate (by 8.3 times, р < 0.05) and severe UC (by 13.2 times, р < 0.05) compared to that of the control group. In addition, with severe UC, the concentration of IL-23 was 1.6 times than in moderate UC. …”
Get full text

Development and validation of a nomogram for predicting cough variant asthma diagnosis by Jiao Min, Xiaomiao Tang, Di Zhang, Jin Yang, Fei Li, Wei Lei

“…A nomogram was constructed using these predictors and validated using Bootstrap resampling (B = 200) to calculate the C-index. Additionally, receiver operating characteristic (ROC) curve analysis and decision curve analysis (DCA) were employed to assess the model's accuracy. …”
Get full text

Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy by Jun Peng, Wenqi Zhao, Lu Zhou, Kun Ding

“…Weighted Gene Co-expression Network Analysis (WGCNA) was employed to screen the DN-related genes, then the differential CSRGs (DCSRGs) were identified, followed by protein–protein interaction (PPI) network construction. In addition, key biomarkers were acquired by two machine learning algorithms, then immune infiltration analysis, Gene Set Enrichment Analysis (GSEA), and potential drugs screening were conducted. …”
Get full text

Machine learning models predicting risk of revision or secondary knee injury after anterior cruciate ligament reconstruction demonstrate variable discriminatory and accuracy perfor... by Benjamin Blackman, Prushoth Vivekanantha, Rafay Mughal, Ayoosh Pareek, Anthony Bozzo, Kristian Samuelsson, Darren de SA

“…Future research should focus on validating current models in addition to developing new multimodal neural networks to improve accuracy and reliability.…”
Get full text

CSGD-YOLO: A Corn Seed Germination Status Detection Model Based on YOLOv8n by Wenbin Sun, Meihan Xu, Kang Xu, Dongquan Chen, Jianhua Wang, Ranbing Yang, Quanquan Chen, Songmei Yang

“…Simultaneously, a detection module dubbed Ghost_Detection, leveraging the GhostConv architecture, is devised to boost detection efficiency while simultaneously reducing parameter counts and computational overhead. Additionally, during the downsampling process of the backbone network, a downsampling module based on receptive field attention convolution (RFAConv) is designed to boost the model’s focus on areas of interest. …”
Get full text

Evaluasi SIMRS pada Manajemen Sumber Daya Manusia dengan Framework COBIT 5 by I Nyoman Angga Prabawa, I Made Oka Widyantara, Made Sudarma

“…Salah satu prasyarat terhadap standar sebuah rumah sakit di Indonesia, termasuk di Rumah Sakit Umum Daerah (RSUD) Klungkung adalah adanya penggunaan Sistem Informasi Manajemen Rumah Sakit (SIMRS). …”
Get full text

New acorane-sesequiterpenes and anti-retinoblastoma constituents from the marine algicolous fungus Trichoderma harzianum NTU2180 guided by molecular networking strategy by Andrea Gu, Fan-Li Lin, Chung-Kuang Lu, Tz-Wei Yeh, Yih-Fung Chen, Ho-Cheng Wu, Tzong-Huei Lee

“…Among them, six compounds (1, 2, 3, 4, 5, and 11) were annotated as terpenoids by the NPClassifier on FBMN. 5-Hydroxy-3-hydroxmethyl-2-methyl-7-methoxychromone (7) and ergosterol peroxide (11) showed significant anti-angiogenic activity in ex vivo experiments with respective 0.57 ± 0.12- and 0.20 ± 0.12-fold changes. In addition, compound 11 displayed cytotoxicity against Y79 retinoblastoma cells with IC50 value of 35.3 ± 6.9 µM. …”
Get full text

Dietary practice and associated factors among lactating mothers in Dangila District in the Awi Zone Amhara region Ethiopia, 2022: a cross-sectional study by Sileshi Mulatu, Getasew Mulatu, Azeb Gedif

“…Additionally, daily laborers exhibited a striking 9.35 times higher likelihood of poor dietary practices (AOR = 9.35; 95% CI: 8.02, 19.96), and food-insecure mothers had 4.93 times higher odds of inadequate nutrition (AOR = 4.93; 95% CI: 3.40, 7.16).ConclusionIn conclusion, the dietary practices of lactating mothers were found to be suboptimal, falling below WHO and FAO recommendations. …”
Get full text

Research on pipeline-type power frequency electromagnetic heating system and multi-layer winding based power regulation method by Feng Zhou, Longyun Liu, Zixuan Wang, Xin Tong, Yanping Liu

“…Temperature field analysis of the heating device demonstrated that setting the fluid inside the pipeline to a certain water flow rate can achieve efficient heating of the fluid. Additionally, for applications requiring power regulation, a multi-layer winding-based power regulation method is proposed. …”
Get full text

Study on the protective effect of naringin-regulated lncRNA GAS5 against mitochondrial apoptosis in osteoarthritic chondrocytes by LIN Qin, ZHU Yingkai, LIN Yanming, LAN Shujie, CHEN Changxing, FU Changlong

“…In vitro experiments, Lenti-lncRNA GAS5 was used to infect sodium nitroprusside (SNP)-induced chondrocytes, and the expression of lncRNA GAS5 was detected by fluorescence in situ hybridization in rat chondrocytes; after silencing of lncRNA GAS5, the expression level of lncRNA GAS5 in rat chondrocytes was detected by Real-time PCR; Western blot detected the protein levels of Caspase-3, Bax, MMP-13 and Cyt-C.Results① Pathological changes of cartilage tissue: The articular cartilage matrix in naringenin group was relatively complete, the surface was relatively smooth, the structure was clear, the tide line was more complete, the number of chondrocytes was more full, the arrangement was more orderly, the cartilage staining was more uniform, and the structure was significantly restored than that in the model group. ② lncRNA GAS5 expression in cartilage tissue: Compared with model group, lncRNA GAS5 expression in naringin group was decreased (<italic>P</italic>&lt;0.01). ③ Expression of proteins related to mitochondrial apoptosis in cartilage tissues: Compared with model group, the expressions of Caspase-3, Bax, MMP-13 and Cyt-C in cartilage tissues of naringin group were decreased (<italic>P</italic>&lt;0.01). ④ Fluorescence expression of lncRNA GAS5 in chondrocytes: FISH results showed that the fluorescence expression of lncRNA GAS5 was decreased after naringin treatment of SNP-induced chondrocytes (<italic>P</italic>&lt;0.01). ⑤ The protein expressions of Caspase-3, Bax, MMP-13 and Cyt-C in chondrocytes: Compared with the model group, the protein expressions of Caspase-3, Bax, MMP-13 and Cyt-C in naringin group were significantly decreased (<italic>P</italic>&lt; 0.01). In addition, silencing lncRNA GAS5 will weaken the therapeutic effect of naringin on OA.ConclusionNaringin inhibits chondrocyte mitochondrial apoptosis and protects degraded cartilage tissues by down-regulating the expression of lncRNA GAS5, which has therapeutic value for OA diseases.…”
Get full text

A machine learning model to predict the risk factors causing feelings of burnout and emotional exhaustion amongst nursing staff in South Africa by Maria Magdalena Van Zyl-Cillié, Jacoba H. Bührmann, Alwiena J. Blignaut, Derya Demirtas, Siedine K. Coetzee

“…The models were evaluated on their accuracy score, Area Under the Curve (AUC) score and confusion matrix performance. Additionally, the accuracy score of models using demographic data alone was compared to the full survey data models. …”
Get full text

The Double-Edged Sword of Third-Party Resources: Examining Use and Financial Burden of Extracurricular Tools in Medical Students [version 2; peer review: 1 approved, 2 approved wit... by Dimitrios Papanagnou, Saaniya Farhan, Andres Fernandez, Meryem Guler, Drake Kienzle, Faizaan Siddique

“…References were mined for additional results, per the discretion of each reviewer. …”
Get full text

Human exploitation of adult horseshoe crab and public awareness campaign in Hong Kong SAR, China by Pui Yi Tang, Hei Wut Fong, Shan Yee Lee, Wing Tung Chang, Lee Yan Pang, Tin Yan Hui, Kelvin Jun Yin So

“…The market survey recorded a total of 80 adult horseshoe crabs for sale in seafood restaurants or fish stalls out of the 98 shops surveyed. In addition, phone interviews revealed a low level of awareness among Hong Kong citizens (N = 1005 respondents), with 53 % having no prior knowledge and never heard of “horseshoe crab”. …”
Get full text

Domestic sewage irrigation on dynamics of nutrients and heavy metals in soil and wheat (Triticum aestivum L.) production by S. R. Salakinkop, C. S. Hunshal

“…None of the treatments did show accumulation of these heavy metals in wheat plant parts more than normal range found in food plants. …”
Get full text

L-shaped association between dietary iron intake and HPV infection: a cross-sectional analysis based on national health and nutrition examination survey 2005–2016 by Xiaotong Chen, Haiwei Chen, Yuling Chen, Lixin Tang, Jiaqi Liu, Yu-Hua Ou

“…To statistically assess this relationship, we utilized weighted multivariate logistic regression models. Additionally, we implemented smooth curve fitting and threshold effect analysis, to delineate the complex, nonlinear association between iron intake and HPV infection. …”
Get full text

Synthesis and evaluation of antitumor activity of new 4-substituted thieno[3,2-d]pyrimidine and thienotriazolopyrimidine derivatives by Hafez Hend N., El-Gazzar Abdel-Rhman B. A.

“…On the other hand, compound 2 was used to synthesize ethyl-[(3-methyl-6-phenyl-2-thioxo-2,3-dihydrothieno[ 3,2-d]pyrimidin-4-yl)-oxy]acetate (10), 2-hydrazinyl- -3-methyl-6-phenyl-thieno[3,2-d]pyrimidin-4(3H)-one (11), 3-methyl-2-(methyl-sulfanyl)-6-phenyl-thieno[3,2-d]pyrimidin- 4(3H)-one (12) and N-(phenyl)/4-chlorophenyl or methoxy- phenyl)-2-[(3-methyl-4-oxo-6-phenyl-3,4-dihydrothieno[ 3,2-d]pyrimidin-2-yl)-sulfanyl]-acetamide (13a-c). In addition, compound 12 was used to synthesize thieno[1,2,4] triazolopyrimidine derivatives 14 and 15 and 3-methyl-2-(methyl-sulfonyl)-6-phenyl-thieno[3,2-d]pyrimidin-4(3H)-one (16) through the reaction with the respective reagents. …”
Get full text